TWI730012B - 化學化合物 - Google Patents
化學化合物 Download PDFInfo
- Publication number
- TWI730012B TWI730012B TW105136236A TW105136236A TWI730012B TW I730012 B TWI730012 B TW I730012B TW 105136236 A TW105136236 A TW 105136236A TW 105136236 A TW105136236 A TW 105136236A TW I730012 B TWI730012 B TW I730012B
- Authority
- TW
- Taiwan
- Prior art keywords
- methyl
- pyridine
- dihydroimidazo
- amino
- pyrazol
- Prior art date
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| US201562252726P | 2015-11-09 | 2015-11-09 | |
| US62/252,726 | 2015-11-09 | ||
| US201662401351P | 2016-09-29 | 2016-09-29 | |
| US62/401,351 | 2016-09-29 |
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| WO2017068412A1 (en) | 2015-10-21 | 2017-04-27 | Otsuka Pharmaceutical Co., Ltd. | Benzolactam compounds as protein kinase inhibitors |
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| GB201706327D0 (en) | 2017-04-20 | 2017-06-07 | Otsuka Pharma Co Ltd | A pharmaceutical compound |
| JP7352981B2 (ja) * | 2018-10-10 | 2023-09-29 | 深▲チェン▼市塔吉瑞生物医薬有限公司 | ジヒドロイミダゾピラジノン化合物、該化合物を含む組成物およびその使用 |
| KR20210145773A (ko) | 2019-03-28 | 2021-12-02 | 지앙수 헨그루이 메디슨 컴퍼니 리미티드 | 티에노헤테로고리형 유도체, 이의 제조 방법 및 이의 의약적 용도 |
| EP3978498A1 (en) | 2019-05-24 | 2022-04-06 | Jiangsu Hengrui Medicine Co., Ltd. | Substituted fused bicyclic derivative, preparation method therefor, and application thereof in medicines |
| PH12021553058A1 (en) | 2019-06-06 | 2022-07-25 | Hutchison Medipharma Ltd | Tricyclic compounds and their use |
| TW202134242A (zh) | 2019-12-05 | 2021-09-16 | 瑞典商阿斯特捷利康公司 | 用於生產式(i)之方法及中間體 |
| EP4071155A4 (en) * | 2019-12-06 | 2024-01-17 | D3 Bio (Wuxi) Co., Ltd. | Thiazololactam compound as erk inhibitor and use thereof |
| US20230331731A1 (en) | 2020-09-29 | 2023-10-19 | Jiangsu Hengrui Pharmaceuticals Co., Ltd. | Crystal form of pyrrolo heterocyclic derivative and preparation method therefor |
| AR126166A1 (es) * | 2021-06-18 | 2023-09-27 | Antengene Discovery Ltd | Combinación de un inhibidor de erk y un inhibidor de kras y usos de estos |
| WO2022268065A1 (en) * | 2021-06-22 | 2022-12-29 | Fochon Biosciences, Ltd. | Compounds as erk inhibitors |
| EP4378478A4 (en) | 2021-07-27 | 2025-11-12 | Toray Industries | MEDICINE FOR THE TREATMENT AND/OR PREVENTION OF CANCER |
| EP4426702A1 (en) | 2021-11-04 | 2024-09-11 | Skyhawk Therapeutics, Inc. | Condensed-pyrazine amine derivatives for treating sca3 |
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| US20260027118A1 (en) | 2022-05-12 | 2026-01-29 | Skyhawk Therapeutics, Inc. | Compositions useful for modulating splicing |
| WO2024006971A2 (en) * | 2022-07-01 | 2024-01-04 | The Scripps Research Institute | Antimalarial compounds |
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