TWI730012B - 化學化合物 - Google Patents
化學化合物 Download PDFInfo
- Publication number
- TWI730012B TWI730012B TW105136236A TW105136236A TWI730012B TW I730012 B TWI730012 B TW I730012B TW 105136236 A TW105136236 A TW 105136236A TW 105136236 A TW105136236 A TW 105136236A TW I730012 B TWI730012 B TW I730012B
- Authority
- TW
- Taiwan
- Prior art keywords
- methyl
- pyridine
- dihydroimidazo
- amino
- pyrazol
- Prior art date
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| US201562252726P | 2015-11-09 | 2015-11-09 | |
| US62/252,726 | 2015-11-09 | ||
| US201662401351P | 2016-09-29 | 2016-09-29 | |
| US62/401,351 | 2016-09-29 |
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| GB201706327D0 (en) | 2017-04-20 | 2017-06-07 | Otsuka Pharma Co Ltd | A pharmaceutical compound |
| EP3845538B1 (en) * | 2018-10-10 | 2023-11-08 | Shenzhen TargetRx, Inc. | Dihydroimidazopyrazinone compound, composition including same, and use thereof |
| WO2020192750A1 (zh) | 2019-03-28 | 2020-10-01 | 江苏恒瑞医药股份有限公司 | 噻吩并杂环类衍生物、其制备方法及其在医药上的应用 |
| JP2022534224A (ja) | 2019-05-24 | 2022-07-28 | 江蘇恒瑞医薬股▲ふん▼有限公司 | 置換縮合二環式誘導体、その調製方法、および医薬におけるその適用 |
| CN113966336B (zh) | 2019-06-06 | 2023-11-07 | 和记黄埔医药（上海）有限公司 | 三环类化合物及其用途 |
| AU2020397222B2 (en) | 2019-12-05 | 2023-07-06 | Astrazeneca Ab | Process and intermediates for the production of formula (i) |
| KR102823103B1 (ko) * | 2019-12-06 | 2025-06-20 | 디3 바이오 (우씨) 컴퍼니, 리미티드 | Erk 억제제로서의 티아졸로락탐 화합물 및 이의 용도 |
| CN116437915B (zh) | 2020-09-29 | 2025-03-18 | 江苏恒瑞医药股份有限公司 | 一种吡咯并杂环类衍生物的晶型及其制备方法 |
| AR126166A1 (es) * | 2021-06-18 | 2023-09-27 | Antengene Discovery Ltd | Combinación de un inhibidor de erk y un inhibidor de kras y usos de estos |
| WO2022268065A1 (en) * | 2021-06-22 | 2022-12-29 | Fochon Biosciences, Ltd. | Compounds as erk inhibitors |
| KR20240041917A (ko) | 2021-07-27 | 2024-04-01 | 도레이 카부시키가이샤 | 암의 치료 및/또는 예방을 위한 의약품 |
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| WO2024006971A2 (en) * | 2022-07-01 | 2024-01-04 | The Scripps Research Institute | Antimalarial compounds |
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