TWI729492B - 使用包含微脂體伊立替康（ｉｒｉｎｏｔｅｃａｎ）的組合療法治療胰臟癌的方法 - Google Patents

使用包含微脂體伊立替康（ｉｒｉｎｏｔｅｃａｎ）的組合療法治療胰臟癌的方法 Download PDF

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TWI729492B
TWI729492B TW108132921A TW108132921A TWI729492B TW I729492 B TWI729492 B TW I729492B TW 108132921 A TW108132921 A TW 108132921A TW 108132921 A TW108132921 A TW 108132921A TW I729492 B TWI729492 B TW I729492B
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irinotecan
treatment
dose
administered
patients
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TW108132921A
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TW202027727A (zh
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艾里爾 拜耶維
奈威里特 丁德薩
喬納森 菲索吉拉德
彼得 萊文斯
維克多 摩優
克雷特 尼伊基扎
金在淵
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英商益普生生技醫藥有限公司
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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    • A61K31/00—Medicinal preparations containing organic active ingredients
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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    • A61K31/00—Medicinal preparations containing organic active ingredients
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    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
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    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
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    • A61K9/00—Medicinal preparations characterised by special physical form
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    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
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    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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TW108132921A 2012-06-13 2013-06-11 使用包含微脂體伊立替康（ｉｒｉｎｏｔｅｃａｎ）的組合療法治療胰臟癌的方法 TWI729492B (zh)

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US201261659211P 2012-06-13 2012-06-13
US61/659,211 2012-06-13
US201361784382P 2013-03-14 2013-03-14
US61/784,382 2013-03-14

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TW202027727A TW202027727A (zh) 2020-08-01
TWI729492B true TWI729492B (zh) 2021-06-01

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TW108132921A TWI729492B (zh) 2012-06-13 2013-06-11 使用包含微脂體伊立替康（ｉｒｉｎｏｔｅｃａｎ）的組合療法治療胰臟癌的方法
TW102120630A TWI630924B (zh) 2012-06-13 2013-06-11 使用包含微脂體伊立替康（ｉｒｉｎｏｔｅｃａｎ）的組合療法治療胰臟癌的方法
TW107116721A TW201831168A (zh) 2012-06-13 2013-06-11 使用包含微脂體伊立替康（ｉｒｉｎｏｔｅｃａｎ）的組合療法治療胰臟癌的方法

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TW102120630A TWI630924B (zh) 2012-06-13 2013-06-11 使用包含微脂體伊立替康（ｉｒｉｎｏｔｅｃａｎ）的組合療法治療胰臟癌的方法
TW107116721A TW201831168A (zh) 2012-06-13 2013-06-11 使用包含微脂體伊立替康（ｉｒｉｎｏｔｅｃａｎ）的組合療法治療胰臟癌的方法

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US (10) US9452162B2 (enExample)
EP (3) EP2861210B1 (enExample)
JP (3) JP6310911B2 (enExample)
KR (3) KR101997206B1 (enExample)
CN (2) CN110051631A (enExample)
AU (3) AU2013202947B2 (enExample)
BR (1) BR112014031088A8 (enExample)
CA (1) CA2875824C (enExample)
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IL (3) IL294886A (enExample)
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PL (2) PL3266456T3 (enExample)
PT (2) PT3266456T (enExample)
RU (1) RU2663450C2 (enExample)
SI (2) SI3266456T1 (enExample)
TW (3) TWI729492B (enExample)
WO (1) WO2013188586A1 (enExample)
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