TWI668010B - 使用ｇｌｐ－１及抗ｉｌ－２１治療糖尿病 - Google Patents
使用ｇｌｐ－１及抗ｉｌ－２１治療糖尿病 Download PDFInfo
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- TWI668010B TWI668010B TW104114239A TW104114239A TWI668010B TW I668010 B TWI668010 B TW I668010B TW 104114239 A TW104114239 A TW 104114239A TW 104114239 A TW104114239 A TW 104114239A TW I668010 B TWI668010 B TW I668010B
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- glp
- agonist
- peptide
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- function inhibitor
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Classifications
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- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/26—Glucagons
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- A—HUMAN NECESSITIES
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- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
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- Molecular Biology (AREA)
- Diabetes (AREA)
- General Chemical & Material Sciences (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Obesity (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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| EP14189732 | 2014-10-21 | ||
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| TW (1) | TWI668010B (enExample) |
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| US20190070266A1 (en) * | 2016-03-04 | 2019-03-07 | Novo Nordisk A/S | Liraglutide in Diabetic Foot Ulcer |
| US12012441B2 (en) | 2020-10-26 | 2024-06-18 | Neptune Biosciences Llc | Engineered human IL-21 cytokines and methods for using the same |
| WO2025257327A1 (en) | 2024-06-13 | 2025-12-18 | Almirall, S.A. | Therapeutic approaches for the management of hidradenitis suppurativa |
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| CN102027011A (zh) * | 2007-12-07 | 2011-04-20 | 津莫吉尼蒂克斯公司 | 抗人il-21单克隆抗体 |
| CN102711805A (zh) * | 2009-11-13 | 2012-10-03 | 赛诺菲-安万特德国有限公司 | 包含glp-1激动剂、胰岛素和甲硫氨酸的药物组合物 |
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| IL128332A0 (en) | 1996-08-30 | 2000-01-31 | Novo Nordisk As | GLP-1 derivatives |
| US7186683B2 (en) | 2000-09-18 | 2007-03-06 | Sanos Bioscience A/S | Use of GLP for the treatment, prevention, diagnosis, and prognosis of bone-related and nutrition-related disorders |
| JP5562510B2 (ja) * | 2001-06-28 | 2014-07-30 | ノヴォ ノルディスク アー／エス | 修飾ｇｌｐ−１の安定な処方剤 |
| JP2005508915A (ja) * | 2001-10-04 | 2005-04-07 | ジェネティックス・インスチチュート・リミテッド・ライアビリティ・カンパニー | インターロイキン２１受容体活性を調節する方法および組成物 |
| EP1515749B1 (en) | 2002-06-14 | 2012-08-15 | Novo Nordisk A/S | Combined use of a modulator of cd3 and a glp-1 compound |
| WO2005023291A2 (en) | 2003-09-11 | 2005-03-17 | Novo Nordisk A/S | Use of glp1-agonists in the treatment of patients with type i diabetes |
| CN100444898C (zh) * | 2003-09-19 | 2008-12-24 | 诺沃挪第克公司 | 治疗肽的清蛋白结合型衍生物 |
| DE602004031455D1 (de) * | 2003-12-09 | 2011-03-31 | Novo Nordisk As | Regulierung der nahrungspräferenz mit glp-1-agonisten |
| US7393827B2 (en) | 2004-12-30 | 2008-07-01 | Diakine Therapeutics, Inc. | Pharmaceutical compositions and methods for restoring β-cell mass and function |
| TWI362392B (en) | 2005-03-18 | 2012-04-21 | Novo Nordisk As | Acylated glp-1 compounds |
| EA013821B1 (ru) | 2005-05-25 | 2010-08-30 | Кьюрдм, Инк. | Проостровковые пептиды человека, их производные и аналоги и способы их применения |
| WO2007005738A2 (en) * | 2005-06-30 | 2007-01-11 | Societe De Conseils De Recherches Et D'applications Scientifiques S.A.S. | Glp-1 pharmaceutical compositions |
| EP1924293A4 (en) | 2005-08-06 | 2008-12-24 | Qinghua Wang | COMPOSITION AND METHOD FOR THE PREVENTION AND TREATMENT OF DIABETES TYPE I |
| DK3524261T5 (da) * | 2005-08-19 | 2024-09-02 | Amylin Pharmaceuticals Llc | Exendin til anvendelse til behandling af diabetes og reduktion af kropsvægt |
| CN101291685A (zh) * | 2005-08-19 | 2008-10-22 | 安米林药品公司 | 治疗糖尿病和降低体重的毒蜥外泌肽 |
| US8084022B2 (en) * | 2006-06-23 | 2011-12-27 | Aegis Therapeutics, Llc | Stabilizing alkylglycoside compositions and methods thereof |
| NZ574710A (en) * | 2006-09-07 | 2012-02-24 | Nycomed Gmbh | Combination treatment comprising the PDE4 inhibitor Compound A ((2R,4aR, 10bR)6-(2,6-Dimethoxy-pyridin-3-yl)-9-ethoxy-8-methoxy-1 ,2,3,4,4a,10b-hexahydrophenanthridin-2-ol) for diabetes mellitus |
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Also Published As
| Publication number | Publication date |
|---|---|
| US10105442B2 (en) | 2018-10-23 |
| RS60316B1 (sr) | 2020-07-31 |
| JP6672175B2 (ja) | 2020-03-25 |
| US20170043014A1 (en) | 2017-02-16 |
| PL3139948T3 (pl) | 2020-08-10 |
| EP3139948A1 (en) | 2017-03-15 |
| JP2017514860A (ja) | 2017-06-08 |
| CN106999553B (zh) | 2021-11-26 |
| EP3139948B1 (en) | 2020-03-04 |
| SI3139948T1 (sl) | 2020-07-31 |
| WO2015169789A1 (en) | 2015-11-12 |
| CN106999553A (zh) | 2017-08-01 |
| TW201625289A (zh) | 2016-07-16 |
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