TWI630009B - 用於雙腔室混合型注射器的組合式活塞裝置 - Google Patents
用於雙腔室混合型注射器的組合式活塞裝置 Download PDFInfo
- Publication number
- TWI630009B TWI630009B TW102143401A TW102143401A TWI630009B TW I630009 B TWI630009 B TW I630009B TW 102143401 A TW102143401 A TW 102143401A TW 102143401 A TW102143401 A TW 102143401A TW I630009 B TWI630009 B TW I630009B
- Authority
- TW
- Taiwan
- Prior art keywords
- piston
- mixing
- syringe
- delivery
- needle
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
- A61M5/178—Syringes
- A61M5/28—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle
- A61M5/284—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle comprising means for injection of two or more media, e.g. by mixing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2093—Containers having several compartments for products to be mixed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
- A61M5/178—Syringes
- A61M5/19—Syringes having more than one chamber
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/3148—Means for causing or aiding aspiration or plunger retraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/3205—Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
- A61M5/321—Means for protection against accidental injuries by used needles
- A61M5/322—Retractable needles, i.e. disconnected from and withdrawn into the syringe barrel by the piston
- A61M5/3234—Fully automatic needle retraction, i.e. in which triggering of the needle does not require a deliberate action by the user
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F31/00—Mixers with shaking, oscillating, or vibrating mechanisms
- B01F31/40—Mixers with shaking, oscillating, or vibrating mechanisms with an axially oscillating rotary stirrer
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F31/00—Mixers with shaking, oscillating, or vibrating mechanisms
- B01F31/44—Mixers with shaking, oscillating, or vibrating mechanisms with stirrers performing an oscillatory, vibratory or shaking movement
- B01F31/441—Mixers with shaking, oscillating, or vibrating mechanisms with stirrers performing an oscillatory, vibratory or shaking movement performing a rectilinear reciprocating movement
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F33/00—Other mixers; Mixing plants; Combinations of mixers
- B01F33/50—Movable or transportable mixing devices or plants
- B01F33/501—Movable mixing devices, i.e. readily shifted or displaced from one place to another, e.g. portable during use
- B01F33/5011—Movable mixing devices, i.e. readily shifted or displaced from one place to another, e.g. portable during use portable during use, e.g. hand-held
- B01F33/50112—Movable mixing devices, i.e. readily shifted or displaced from one place to another, e.g. portable during use portable during use, e.g. hand-held of the syringe or cartridge type
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/20—Measuring; Control or regulation
- B01F35/22—Control or regulation
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/71—Feed mechanisms
- B01F35/716—Feed mechanisms characterised by the relative arrangement of the containers for feeding or mixing the components
- B01F35/7162—A container being placed inside the other before contacting the contents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M2005/3117—Means preventing contamination of the medicament compartment of a syringe
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/3205—Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
- A61M5/321—Means for protection against accidental injuries by used needles
- A61M5/322—Retractable needles, i.e. disconnected from and withdrawn into the syringe barrel by the piston
- A61M5/3221—Constructional features thereof, e.g. to improve manipulation or functioning
- A61M2005/3231—Proximal end of needle captured or embedded inside piston head, e.g. by friction or hooks
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/3205—Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
- A61M5/321—Means for protection against accidental injuries by used needles
- A61M5/322—Retractable needles, i.e. disconnected from and withdrawn into the syringe barrel by the piston
- A61M5/3234—Fully automatic needle retraction, i.e. in which triggering of the needle does not require a deliberate action by the user
- A61M2005/3235—Fully automatic needle retraction, i.e. in which triggering of the needle does not require a deliberate action by the user triggered by radial deflection of the anchoring parts between needle mount and syringe barrel or needle housing, e.g. spreading of needle mount retaining hooks having slanted surfaces by engagement with correspondingly shaped surfaces on the piston at the end of an injection stroke
- A61M2005/3238—Trigger provided at the proximal end, i.e. syringe end opposite to needle mounting end
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/0007—Special media to be introduced, removed or treated introduced into the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2207/00—Methods of manufacture, assembly or production
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31596—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms comprising means for injection of two or more media, e.g. by mixing
- A61M5/31598—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms comprising means for injection of two or more media, e.g. by mixing having multiple telescopically sliding coaxial pistons encompassing volumes for components to be mixed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/3205—Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
- A61M5/321—Means for protection against accidental injuries by used needles
- A61M5/322—Retractable needles, i.e. disconnected from and withdrawn into the syringe barrel by the piston
- A61M5/3221—Constructional features thereof, e.g. to improve manipulation or functioning
Landscapes
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Anesthesiology (AREA)
- Vascular Medicine (AREA)
- Environmental & Geological Engineering (AREA)
- Pharmacology & Pharmacy (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261731972P | 2012-11-30 | 2012-11-30 | |
| US61/731,972 | 2012-11-30 | ||
| PCT/US2013/070494 WO2014085118A1 (en) | 2012-11-30 | 2013-11-18 | Combination plunger device for a dual chamber mixing syringe |
| ??PCT/US2013/070494 | 2013-11-18 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TW201429511A TW201429511A (zh) | 2014-08-01 |
| TWI630009B true TWI630009B (zh) | 2018-07-21 |
Family
ID=49709841
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW102143401A TWI630009B (zh) | 2012-11-30 | 2013-11-28 | 用於雙腔室混合型注射器的組合式活塞裝置 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US10130768B2 (enExample) |
| EP (1) | EP2925391B1 (enExample) |
| JP (1) | JP6362145B2 (enExample) |
| AU (1) | AU2013353059B2 (enExample) |
| CA (1) | CA2892088A1 (enExample) |
| DK (1) | DK2925391T3 (enExample) |
| PT (1) | PT2925391T (enExample) |
| TW (1) | TWI630009B (enExample) |
| WO (1) | WO2014085118A1 (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6186379B2 (ja) | 2012-02-10 | 2017-08-23 | カウンスィル オブ サイエンティフィック アンド インダストリアル リサーチCouncil Of Scientific & Industrial Research | 遊離生体アミノ酸の精製のための無溶媒プロセス |
| US9522235B2 (en) | 2012-05-22 | 2016-12-20 | Kaleo, Inc. | Devices and methods for delivering medicaments from a multi-chamber container |
| US10130768B2 (en) | 2012-11-30 | 2018-11-20 | Unl Holdings Llc | Combination plunger device for a dual chamber mixing syringe |
| KR20170097020A (ko) | 2014-12-23 | 2017-08-25 | 오토메드 피티와이 리미티드 | 딜리버리 장치, 시스템 및 관련 방법 |
| US10695495B2 (en) | 2015-03-24 | 2020-06-30 | Kaleo, Inc. | Devices and methods for delivering a lyophilized medicament |
| DE102015112203A1 (de) * | 2015-07-27 | 2017-02-02 | Aap Biomaterials Gmbh | Mischvorrichtung, insbesondere für Knochenzement |
| SG10201509159TA (en) * | 2015-11-05 | 2017-06-29 | Arrow-Med Design Pte Ltd | Injection device |
| US10960144B2 (en) | 2016-11-01 | 2021-03-30 | Credence Medsystems, Inc. | System and method for safety syringe |
| EP3655070B1 (en) * | 2017-07-21 | 2025-08-27 | Becton Dickinson France | Assisted injection device for injecting a composition contained in a medical container with reduced efforts |
| USD1141122S1 (en) | 2017-09-15 | 2026-08-11 | Ethan Pedde | Volume limiter device |
| US10675416B2 (en) * | 2018-08-17 | 2020-06-09 | David Harold Kovacs | Retractable syringe |
| EP3738628A1 (de) * | 2019-05-16 | 2020-11-18 | Trenta2 S.r.l. | Medizinische spritze mit passivem nadelschutz |
| US11957542B2 (en) | 2020-04-30 | 2024-04-16 | Automed Patent Holdco, Llc | Sensing complete injection for animal injection device |
| EP4171683A4 (en) | 2020-06-30 | 2024-07-24 | Davol Inc. | MULTIPLE CHAMBER SYRINGE |
| US20230321361A1 (en) * | 2020-09-08 | 2023-10-12 | Trenta2 S.r.l. | Medical syringe with passive needle protection |
| US12220118B2 (en) | 2022-03-31 | 2025-02-11 | Ethicon, Inc. | Systems, devices and methods for reconstituting therapeutic powders, mixing precursor solutions, and expressing sealants for controlling bleeding and sealing fluid and air leaks |
| US12114843B2 (en) | 2022-03-31 | 2024-10-15 | Ethicon, Inc. | Sealant applicators having mixing and spraying assemblies with malleable sections and spray tips having reduced dimensions |
| US20240245863A1 (en) * | 2023-01-24 | 2024-07-25 | Gino Bradica | Separation Syringe and Processing Methods For Separation of Biological Fluids Into Fractions |
| USD1128904S1 (en) | 2023-12-08 | 2026-06-02 | Novo Nordisk Us Holdings, Inc. | Injection device |
| US12083318B1 (en) * | 2023-12-19 | 2024-09-10 | Albert Bold | Syringe assembly |
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| US20100082015A1 (en) * | 2008-09-30 | 2010-04-01 | Tyco Healthcare Group Lp | Device for Interfacing with Standard Luer Lock Syringes |
| CN102143776A (zh) * | 2008-07-04 | 2011-08-03 | Shl集团有限责任公司 | 带混合机构的药物输送器件 |
| CN102648014A (zh) * | 2009-12-04 | 2012-08-22 | 欧文蒙福德有限公司 | 注射设备 |
| CN102695533A (zh) * | 2009-11-11 | 2012-09-26 | 尤尼特拉克特注射器公司 | 医用注射器 |
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| US2591706A (en) | 1950-09-29 | 1952-04-08 | Compule Corp | Plural-compartment admixing hypodermic syringe ampoule for segregated storage of ingredients of liquid medicinal solutions and therapeutic preparations |
| NL106573C (enExample) | 1957-05-31 | |||
| AT318132B (de) | 1969-08-01 | 1974-09-25 | Dentaire Ivoclar Ets | Mischbehälter für die Aufnahme von miteinander reagierenden Substanzen für die Herstellung von gebrauchsfertigen pastenförmigen Dentalpräparaten |
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2013
- 2013-11-18 US US14/648,376 patent/US10130768B2/en not_active Expired - Fee Related
- 2013-11-18 DK DK13799451.3T patent/DK2925391T3/en active
- 2013-11-18 PT PT137994513T patent/PT2925391T/pt unknown
- 2013-11-18 JP JP2015545085A patent/JP6362145B2/ja not_active Expired - Fee Related
- 2013-11-18 CA CA2892088A patent/CA2892088A1/en not_active Abandoned
- 2013-11-18 WO PCT/US2013/070494 patent/WO2014085118A1/en not_active Ceased
- 2013-11-18 EP EP13799451.3A patent/EP2925391B1/en not_active Not-in-force
- 2013-11-18 AU AU2013353059A patent/AU2013353059B2/en not_active Ceased
- 2013-11-28 TW TW102143401A patent/TWI630009B/zh not_active IP Right Cessation
-
2018
- 2018-10-16 US US16/161,759 patent/US11191902B2/en not_active Expired - Fee Related
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Also Published As
| Publication number | Publication date |
|---|---|
| US10130768B2 (en) | 2018-11-20 |
| AU2013353059A1 (en) | 2015-07-02 |
| EP2925391A1 (en) | 2015-10-07 |
| WO2014085118A1 (en) | 2014-06-05 |
| EP2925391B1 (en) | 2017-05-03 |
| TW201429511A (zh) | 2014-08-01 |
| US11191902B2 (en) | 2021-12-07 |
| CA2892088A1 (en) | 2014-06-05 |
| JP2015536204A (ja) | 2015-12-21 |
| US20150320935A1 (en) | 2015-11-12 |
| JP6362145B2 (ja) | 2018-07-25 |
| AU2013353059B2 (en) | 2018-07-05 |
| US20190217010A1 (en) | 2019-07-18 |
| PT2925391T (pt) | 2017-08-10 |
| DK2925391T3 (en) | 2017-08-28 |
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Legal Events
| Date | Code | Title | Description |
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| MM4A | Annulment or lapse of patent due to non-payment of fees |