TWI592156B - 使用胺基吡啶以治療與中風有關之感覺動作損傷之方法 - Google Patents

使用胺基吡啶以治療與中風有關之感覺動作損傷之方法 Download PDF

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Publication number
TWI592156B
TWI592156B TW101136564A TW101136564A TWI592156B TW I592156 B TWI592156 B TW I592156B TW 101136564 A TW101136564 A TW 101136564A TW 101136564 A TW101136564 A TW 101136564A TW I592156 B TWI592156 B TW I592156B
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TW
Taiwan
Prior art keywords
months
aminopyridine
stroke
weeks
days
Prior art date
Application number
TW101136564A
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English (en)
Chinese (zh)
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TW201321000A (zh
Inventor
安德魯R 布萊特
安東尼O 卡吉亞諾
湯姆J 派瑞
珍妮佛F 艾希
Original Assignee
艾可達醫療公司
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Publication of TW201321000A publication Critical patent/TW201321000A/zh
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Publication of TWI592156B publication Critical patent/TWI592156B/zh

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4409—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 4, e.g. isoniazid, iproniazid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Psychology (AREA)
  • Urology & Nephrology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
TW101136564A 2011-10-04 2012-10-03 使用胺基吡啶以治療與中風有關之感覺動作損傷之方法 TWI592156B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161543150P 2011-10-04 2011-10-04
US201261591833P 2012-01-27 2012-01-27
US201261648695P 2012-05-18 2012-05-18

Publications (2)

Publication Number Publication Date
TW201321000A TW201321000A (zh) 2013-06-01
TWI592156B true TWI592156B (zh) 2017-07-21

Family

ID=47143280

Family Applications (1)

Application Number Title Priority Date Filing Date
TW101136564A TWI592156B (zh) 2011-10-04 2012-10-03 使用胺基吡啶以治療與中風有關之感覺動作損傷之方法

Country Status (22)

Country Link
US (2) US20130085167A1 (enExample)
EP (1) EP2766017B1 (enExample)
JP (1) JP6134722B2 (enExample)
KR (1) KR20140084120A (enExample)
CN (2) CN104220072B (enExample)
AR (1) AR088764A1 (enExample)
AU (2) AU2012318719B2 (enExample)
BR (1) BR112014008082A8 (enExample)
CA (1) CA2850635A1 (enExample)
CL (1) CL2014000799A1 (enExample)
CO (1) CO7061067A2 (enExample)
CR (1) CR20140153A (enExample)
EA (1) EA029558B1 (enExample)
HK (1) HK1201204A1 (enExample)
IL (1) IL231809B (enExample)
MX (1) MX354667B (enExample)
PH (1) PH12014500739B1 (enExample)
SG (2) SG11201401248YA (enExample)
TW (1) TWI592156B (enExample)
UA (1) UA114486C2 (enExample)
WO (1) WO2013052575A1 (enExample)
ZA (1) ZA201402432B (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2909527A1 (en) * 2013-04-15 2014-10-23 Acorda Therapeutics, Inc. Methods for treating sensorimotor impairments associated with certain types of stroke using aminopyridines
US10172842B2 (en) 2015-09-11 2019-01-08 PharmaDax Inc. Sustained release oral dosage form containing dalfampridine
DE102017115701B4 (de) * 2017-07-12 2022-03-03 Lts Lohmann Therapie-Systeme Ag Fampridin-TTS
CN109172573B (zh) * 2018-09-12 2021-01-26 黑龙江中桂制药有限公司 一种口服抗血栓药物及其用途
CN115018836A (zh) * 2022-08-08 2022-09-06 四川大学 一种癫痫病灶自动分割与预测方法、系统及设备

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0696575B2 (ja) * 1987-09-17 1994-11-30 三菱化成株式会社 4−アミノピリジン誘導体及びその酸付加塩
WO1989009600A1 (en) 1988-04-08 1989-10-19 Massachusetts Institute Of Technology Method and composition for treating neurological disorders
IE82916B1 (en) 1990-11-02 2003-06-11 Elan Corp Plc Formulations and their use in the treatment of neurological diseases
CA2085785C (en) * 1992-12-18 2005-03-15 Robert R. Hansebout The use of 4-aminopyridine in the treatment of a neurological condition
US5952357A (en) 1993-12-23 1999-09-14 Cornell Research Foundation, Inc. Treating diseases of the anterior horn cells
EP1152760B1 (en) * 1999-02-09 2007-03-28 UAB Research Foundation Use of 4-amino pyridine for treatment of peripheral neuropathies
FR2791571B1 (fr) * 1999-04-02 2002-10-04 Sod Conseils Rech Applic Association inhibiteur(s) de no synthase et antioxydant(s) metabolique(s)
CA2403555A1 (en) * 2000-03-28 2001-10-04 Queen's University At Kingston Methods for effecting neuroprotection
GB0119435D0 (en) * 2001-02-15 2001-10-03 Aventis Pharm Prod Inc Method of treating of demyelinating diseases or conditions
US8007826B2 (en) * 2003-12-11 2011-08-30 Acorda Therapeutics, Inc. Sustained release aminopyridine composition
US8354437B2 (en) 2004-04-09 2013-01-15 Acorda Therapeutics, Inc. Method of using sustained release aminopyridine compositions
EP2667869A1 (en) * 2011-01-28 2013-12-04 Acorda Therapeutics, Inc. Use of potassium channel blockers to treat cerebral palsy

Also Published As

Publication number Publication date
JP6134722B2 (ja) 2017-05-24
AU2012318719A1 (en) 2014-04-17
SG11201401248YA (en) 2014-05-29
US20130085167A1 (en) 2013-04-04
EA029558B1 (ru) 2018-04-30
CR20140153A (es) 2014-07-04
KR20140084120A (ko) 2014-07-04
IL231809A0 (en) 2014-05-28
CN104220072B (zh) 2018-04-17
NZ623255A (en) 2016-08-26
UA114486C2 (uk) 2017-06-26
SG10201600410SA (en) 2016-02-26
PH12014500739A1 (en) 2014-05-26
IL231809B (en) 2019-06-30
MX354667B (es) 2018-03-15
TW201321000A (zh) 2013-06-01
ZA201402432B (en) 2020-08-26
AU2012318719B2 (en) 2017-10-19
PH12014500739B1 (en) 2019-05-10
US20160067232A1 (en) 2016-03-10
WO2013052575A1 (en) 2013-04-11
BR112014008082A8 (pt) 2018-01-16
EP2766017A1 (en) 2014-08-20
CA2850635A1 (en) 2013-04-11
AU2018200114A1 (en) 2018-01-25
EP2766017B1 (en) 2020-07-01
HK1204965A1 (en) 2015-12-11
CL2014000799A1 (es) 2014-11-03
CO7061067A2 (es) 2014-09-19
BR112014008082A2 (pt) 2017-07-18
CN104220072A (zh) 2014-12-17
JP2014531470A (ja) 2014-11-27
EA201490562A1 (ru) 2014-08-29
MX2014003997A (es) 2014-07-22
HK1201204A1 (en) 2015-08-28
AR088764A1 (es) 2014-07-02
CN108451953A (zh) 2018-08-28

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