TWI567375B - 光元件、分析裝置及分光方法 - Google Patents
光元件、分析裝置及分光方法 Download PDFInfo
- Publication number
- TWI567375B TWI567375B TW100114336A TW100114336A TWI567375B TW I567375 B TWI567375 B TW I567375B TW 100114336 A TW100114336 A TW 100114336A TW 100114336 A TW100114336 A TW 100114336A TW I567375 B TWI567375 B TW I567375B
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- Prior art keywords
- incident
- wavelength
- light
- raman scattering
- resonance peak
- Prior art date
Links
- 230000003287 optical effect Effects 0.000 title claims description 59
- 238000004611 spectroscopical analysis Methods 0.000 title description 5
- 238000001069 Raman spectroscopy Methods 0.000 claims description 74
- 238000000034 method Methods 0.000 claims description 48
- 230000005284 excitation Effects 0.000 claims description 47
- 238000004416 surface enhanced Raman spectroscopy Methods 0.000 claims description 36
- 239000004020 conductor Substances 0.000 claims description 22
- 238000004458 analytical method Methods 0.000 claims description 14
- 239000006185 dispersion Substances 0.000 claims description 11
- 239000000284 extract Substances 0.000 claims description 2
- 239000002184 metal Substances 0.000 description 72
- 229910052751 metal Inorganic materials 0.000 description 72
- 239000000758 substrate Substances 0.000 description 44
- 230000005684 electric field Effects 0.000 description 36
- 230000035945 sensitivity Effects 0.000 description 16
- 239000010419 fine particle Substances 0.000 description 11
- 230000008569 process Effects 0.000 description 11
- 230000010287 polarization Effects 0.000 description 10
- 230000000694 effects Effects 0.000 description 9
- 239000010931 gold Substances 0.000 description 9
- 239000010408 film Substances 0.000 description 8
- 230000000052 comparative effect Effects 0.000 description 7
- 230000008859 change Effects 0.000 description 6
- 238000000862 absorption spectrum Methods 0.000 description 5
- 230000002708 enhancing effect Effects 0.000 description 5
- 230000001965 increasing effect Effects 0.000 description 5
- 239000013076 target substance Substances 0.000 description 5
- 238000002835 absorbance Methods 0.000 description 4
- 238000010586 diagram Methods 0.000 description 4
- 239000003574 free electron Substances 0.000 description 4
- 239000011521 glass Substances 0.000 description 4
- 239000000463 material Substances 0.000 description 4
- 238000012986 modification Methods 0.000 description 4
- 230000004048 modification Effects 0.000 description 4
- 230000003204 osmotic effect Effects 0.000 description 4
- 238000001179 sorption measurement Methods 0.000 description 4
- 238000003745 diagnosis Methods 0.000 description 3
- 239000002923 metal particle Substances 0.000 description 3
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Substances [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 description 3
- 238000001228 spectrum Methods 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- 238000002198 surface plasmon resonance spectroscopy Methods 0.000 description 3
- 239000010409 thin film Substances 0.000 description 3
- XKRFYHLGVUSROY-UHFFFAOYSA-N Argon Chemical compound [Ar] XKRFYHLGVUSROY-UHFFFAOYSA-N 0.000 description 2
- 238000001237 Raman spectrum Methods 0.000 description 2
- 230000005260 alpha ray Effects 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 239000010949 copper Substances 0.000 description 2
- 230000008878 coupling Effects 0.000 description 2
- 238000010168 coupling process Methods 0.000 description 2
- 238000005859 coupling reaction Methods 0.000 description 2
- 229910052737 gold Inorganic materials 0.000 description 2
- 238000007689 inspection Methods 0.000 description 2
- 230000003993 interaction Effects 0.000 description 2
- 238000005259 measurement Methods 0.000 description 2
- 229910052709 silver Inorganic materials 0.000 description 2
- 230000003595 spectral effect Effects 0.000 description 2
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 229910052782 aluminium Inorganic materials 0.000 description 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
- 230000003444 anaesthetic effect Effects 0.000 description 1
- 239000000427 antigen Substances 0.000 description 1
- 102000036639 antigens Human genes 0.000 description 1
- 108091007433 antigens Proteins 0.000 description 1
- 229910052786 argon Inorganic materials 0.000 description 1
- 235000013361 beverage Nutrition 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 229910052802 copper Inorganic materials 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 230000006866 deterioration Effects 0.000 description 1
- 238000006073 displacement reaction Methods 0.000 description 1
- 238000002848 electrochemical method Methods 0.000 description 1
- -1 excitation light Substances 0.000 description 1
- 239000002360 explosive Substances 0.000 description 1
- 239000011888 foil Substances 0.000 description 1
- 239000003193 general anesthetic agent Substances 0.000 description 1
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 230000010354 integration Effects 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 150000002739 metals Chemical class 0.000 description 1
- 239000011859 microparticle Substances 0.000 description 1
- 239000002086 nanomaterial Substances 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 230000000737 periodic effect Effects 0.000 description 1
- 239000000575 pesticide Substances 0.000 description 1
- 230000000704 physical effect Effects 0.000 description 1
- 229910052697 platinum Inorganic materials 0.000 description 1
- 229910021420 polycrystalline silicon Inorganic materials 0.000 description 1
- 229920005591 polysilicon Polymers 0.000 description 1
- 230000001902 propagating effect Effects 0.000 description 1
- 239000010453 quartz Substances 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 229910052594 sapphire Inorganic materials 0.000 description 1
- 239000010980 sapphire Substances 0.000 description 1
- 239000004065 semiconductor Substances 0.000 description 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N silicon dioxide Inorganic materials O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 1
- 239000004332 silver Substances 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- 238000004073 vulcanization Methods 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/27—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using photo-electric detection ; circuits for computing concentration
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/65—Raman scattering
- G01N21/658—Raman scattering enhancement Raman, e.g. surface plasmons
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/55—Specular reflectivity
- G01N21/552—Attenuated total reflection
- G01N21/553—Attenuated total reflection and using surface plasmons
- G01N21/554—Attenuated total reflection and using surface plasmons detecting the surface plasmon resonance of nanostructured metals, e.g. localised surface plasmon resonance
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/65—Raman scattering
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Nanotechnology (AREA)
- Mathematical Physics (AREA)
- Theoretical Computer Science (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2010103035A JP5609241B2 (ja) | 2010-04-28 | 2010-04-28 | 分光方法及び分析装置 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TW201213791A TW201213791A (en) | 2012-04-01 |
| TWI567375B true TWI567375B (zh) | 2017-01-21 |
Family
ID=44317620
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW100114336A TWI567375B (zh) | 2010-04-28 | 2011-04-25 | 光元件、分析裝置及分光方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US8848182B2 (enExample) |
| EP (1) | EP2383565A1 (enExample) |
| JP (1) | JP5609241B2 (enExample) |
| KR (1) | KR20110120233A (enExample) |
| CN (1) | CN102608823B (enExample) |
| TW (1) | TWI567375B (enExample) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5560891B2 (ja) * | 2010-05-13 | 2014-07-30 | セイコーエプソン株式会社 | 光デバイス及び分析装置 |
| JP5821511B2 (ja) | 2011-10-17 | 2015-11-24 | セイコーエプソン株式会社 | 光デバイス及び検出装置 |
| KR101333482B1 (ko) * | 2012-03-08 | 2013-11-26 | 단국대학교 산학협력단 | 표면 플라즈몬 산란 및 공명 검출에 기반한 생체 물질 측정 시스템 |
| JP5928026B2 (ja) * | 2012-03-15 | 2016-06-01 | セイコーエプソン株式会社 | センサーチップおよびその製造方法並びに検出装置 |
| JP2013234941A (ja) * | 2012-05-10 | 2013-11-21 | Seiko Epson Corp | センサーチップ並びにセンサーカートリッジおよび検出装置 |
| JP2014169955A (ja) | 2013-03-05 | 2014-09-18 | Seiko Epson Corp | 分析装置、分析方法、これらに用いる光学素子および電子機器、並びに光学素子の設計方法 |
| JP2014206463A (ja) * | 2013-04-12 | 2014-10-30 | 日本精工株式会社 | 標的物質捕捉装置 |
| JP6180834B2 (ja) * | 2013-07-24 | 2017-08-16 | 株式会社クラレ | プラズモン共鳴構造体 |
| US9297772B2 (en) | 2013-07-30 | 2016-03-29 | Industrial Technology Research Institute | Apparatus for amplifying intensity during transmission small angle—X-ray scattering measurements |
| JP6269008B2 (ja) * | 2013-12-12 | 2018-01-31 | 株式会社豊田中央研究所 | 電磁波−表面ポラリトン変換素子。 |
| KR101494679B1 (ko) * | 2013-12-30 | 2015-02-24 | 한국과학기술원 | 표면 증강 라만 산란을 위한 국부 표면 플라즈몬 공명 파장의 설계 방법 |
| JP6365817B2 (ja) | 2014-02-17 | 2018-08-01 | セイコーエプソン株式会社 | 分析装置、及び電子機器 |
| JP2015152492A (ja) * | 2014-02-17 | 2015-08-24 | セイコーエプソン株式会社 | 分析装置、及び電子機器 |
| JP2016142617A (ja) * | 2015-02-02 | 2016-08-08 | セイコーエプソン株式会社 | 電場増強素子、分析装置、及び電子機器 |
| JP6613736B2 (ja) * | 2015-09-07 | 2019-12-04 | セイコーエプソン株式会社 | 物質検出方法および物質検出装置 |
| US9772290B2 (en) * | 2015-10-23 | 2017-09-26 | King Fahd University Of Petroleum And Minerals | Anisotropic monolayer gold nanoassembly: a highly SERS-active substrate for molecular detection |
| CN106125175A (zh) * | 2016-06-24 | 2016-11-16 | 中国科学院长春光学精密机械与物理研究所 | 一种慢光结构、吸光度检测方法及微流控芯片 |
| US20190391302A1 (en) * | 2017-01-30 | 2019-12-26 | Aalto University Foundation Sr | A plasmonic device |
| CN110244392B (zh) * | 2019-07-31 | 2021-07-20 | 华中科技大学 | 一种不对称传输器 |
| JP7210067B2 (ja) * | 2019-08-02 | 2023-01-23 | 国立研究開発法人物質・材料研究機構 | 光センサー、センサーユニット及び光センサーを利用した物体検出装置 |
| JP7534984B2 (ja) | 2021-03-03 | 2024-08-15 | 株式会社日立ハイテク | 分光測定装置 |
| US11959859B2 (en) * | 2021-06-02 | 2024-04-16 | Edwin Thomas Carlen | Multi-gas detection system and method |
| US20240248033A1 (en) * | 2023-01-19 | 2024-07-25 | Academia Sinica | Surface Plasmon Resonance Sensor, Surface Plasmon Resonance Sensing Instrument Comprising the Same and Method for Detecting an Analyte Using the Same |
| KR102897525B1 (ko) * | 2025-05-30 | 2025-12-08 | 경찰대학 산학협력단 | 인공지능 기반 지능형 마약류 탐지 시스템 |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW200718937A (en) * | 2005-11-03 | 2007-05-16 | Ind Tech Res Inst | Coupled waveguide-surface plasmon resonance biosensor |
| JP2008519254A (ja) * | 2004-11-04 | 2008-06-05 | ディー３ テクノロジーズ リミテッド | 増強ラマン分光法のための金属ナノ空隙フォトニック結晶 |
| US7397559B1 (en) * | 2007-01-23 | 2008-07-08 | Hewlett-Packard Development Company, L.P. | Surface plasmon enhanced Raman spectroscopy |
| JP2009250951A (ja) * | 2008-04-11 | 2009-10-29 | Fujifilm Corp | 電場増強光デバイス |
| US20100067000A1 (en) * | 2004-09-10 | 2010-03-18 | University Of Southampton | Raman spectroscopy |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4209471B2 (ja) * | 1997-02-20 | 2009-01-14 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | プラズモン共鳴粒子、方法、および装置 |
| JP3452837B2 (ja) | 1999-06-14 | 2003-10-06 | 理化学研究所 | 局在プラズモン共鳴センサー |
| JP2005016963A (ja) * | 2003-06-23 | 2005-01-20 | Canon Inc | 化学センサ、化学センサ装置 |
| JP2006093055A (ja) | 2004-09-27 | 2006-04-06 | Toshiba Corp | 画像表示装置 |
| EP2278301A1 (en) | 2004-11-04 | 2011-01-26 | Renishaw Diagnostics Limited | Metal nano-void photonic crystal for enhanced raman spectroscopy |
| JP4117665B2 (ja) * | 2005-03-03 | 2008-07-16 | 独立行政法人物質・材料研究機構 | 光学分析用チップとその製造方法、光学分析用装置、および光学分析方法 |
| JP2006308511A (ja) * | 2005-05-02 | 2006-11-09 | Canon Inc | 化学分析装置及びその分析方法 |
| US7599066B2 (en) | 2005-06-01 | 2009-10-06 | Canon Kabushiki Kaisha | Localized plasmon resonance sensor |
| JP4878216B2 (ja) | 2005-06-01 | 2012-02-15 | キヤノン株式会社 | 局在プラズモン共鳴センサおよび局在プラズモン共鳴センサによる検出方法 |
| WO2008073601A2 (en) * | 2006-10-31 | 2008-06-19 | Trustees Of Boston University | Deterministic aperiodic patterned dielectric and plasmonic materials for localized electromagnetic field enhancement |
| US7639355B2 (en) * | 2007-06-26 | 2009-12-29 | Hewlett-Packard Development Company, L.P. | Electric-field-enhancement structure and detection apparatus using same |
| US8223331B2 (en) * | 2009-06-19 | 2012-07-17 | Hewlett-Packard Development Company, L.P. | Signal-amplification device for surface enhanced raman spectroscopy |
| US8865402B2 (en) * | 2009-08-26 | 2014-10-21 | Clemson University Research Foundation | Nanostructured substrates for surface enhanced raman spectroscopy (SERS) and detection of biological and chemical analytes by electrical double layer (EDL) capacitance |
-
2010
- 2010-04-28 JP JP2010103035A patent/JP5609241B2/ja active Active
-
2011
- 2011-04-25 TW TW100114336A patent/TWI567375B/zh active
- 2011-04-27 CN CN201110107698.3A patent/CN102608823B/zh active Active
- 2011-04-27 US US13/095,103 patent/US8848182B2/en active Active
- 2011-04-27 KR KR20110039320A patent/KR20110120233A/ko not_active Withdrawn
- 2011-04-28 EP EP20110164070 patent/EP2383565A1/en not_active Withdrawn
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100067000A1 (en) * | 2004-09-10 | 2010-03-18 | University Of Southampton | Raman spectroscopy |
| JP2008519254A (ja) * | 2004-11-04 | 2008-06-05 | ディー３ テクノロジーズ リミテッド | 増強ラマン分光法のための金属ナノ空隙フォトニック結晶 |
| TW200718937A (en) * | 2005-11-03 | 2007-05-16 | Ind Tech Res Inst | Coupled waveguide-surface plasmon resonance biosensor |
| US7397559B1 (en) * | 2007-01-23 | 2008-07-08 | Hewlett-Packard Development Company, L.P. | Surface plasmon enhanced Raman spectroscopy |
| JP2009250951A (ja) * | 2008-04-11 | 2009-10-29 | Fujifilm Corp | 電場増強光デバイス |
Also Published As
| Publication number | Publication date |
|---|---|
| JP5609241B2 (ja) | 2014-10-22 |
| EP2383565A1 (en) | 2011-11-02 |
| US20110267613A1 (en) | 2011-11-03 |
| CN102608823B (zh) | 2016-02-03 |
| CN102608823A (zh) | 2012-07-25 |
| TW201213791A (en) | 2012-04-01 |
| US8848182B2 (en) | 2014-09-30 |
| JP2011232186A (ja) | 2011-11-17 |
| KR20110120233A (ko) | 2011-11-03 |
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