TWI528964B - 治療關節失調之長效藥劑 - Google Patents
治療關節失調之長效藥劑 Download PDFInfo
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- TWI528964B TWI528964B TW102138965A TW102138965A TWI528964B TW I528964 B TWI528964 B TW I528964B TW 102138965 A TW102138965 A TW 102138965A TW 102138965 A TW102138965 A TW 102138965A TW I528964 B TWI528964 B TW I528964B
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Classifications
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/728—Hyaluronic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/738—Cross-linked polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
- C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Dermatology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Rheumatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Materials Engineering (AREA)
- Biochemistry (AREA)
- Polymers & Plastics (AREA)
- Inorganic Chemistry (AREA)
- Neurology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US86879806P | 2006-12-06 | 2006-12-06 |
Publications (2)
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| TW201414479A TW201414479A (zh) | 2014-04-16 |
| TWI528964B true TWI528964B (zh) | 2016-04-11 |
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| TW096146443A TWI419697B (zh) | 2006-12-06 | 2007-12-06 | 治療關節失調之長效藥劑 |
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| TW096146443A TWI419697B (zh) | 2006-12-06 | 2007-12-06 | 治療關節失調之長效藥劑 |
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| EP (3) | EP2386306A1 (enExample) |
| JP (3) | JP5291621B2 (enExample) |
| KR (1) | KR101460815B1 (enExample) |
| CN (2) | CN101573123B (enExample) |
| AU (1) | AU2007328871B2 (enExample) |
| CA (1) | CA2672002C (enExample) |
| TW (2) | TWI528964B (enExample) |
| WO (1) | WO2008069348A1 (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2008069348A1 (en) | 2006-12-06 | 2008-06-12 | Seikagaku Corporation | Pharmaceutical agent having long-lasting effect of treating arthritic disorders |
| JO3008B1 (ar) | 2009-08-13 | 2016-09-05 | Seikagaku Kogyo Co Ltd | تركيب صيدلي لتخفيف الألم |
| ITTO20110428A1 (it) * | 2011-05-13 | 2012-11-14 | Rottapharm Spa | Esteri dell'acido ialuronico, loro preparazione ed uso in dermatologia |
| JO3564B1 (ar) | 2013-03-08 | 2020-07-05 | Novartis Ag | ببتيدات وتركيبات لعلاج ضرر المفاصل |
| US9301971B2 (en) | 2013-03-08 | 2016-04-05 | Novartis Ag | Peptides and compositions for treatment of joint damage |
| EP3020733A4 (en) | 2013-07-08 | 2017-03-15 | Denka Company Limited | Core-shell crosslinked hyaluronic acid gel particles, production method for same, and medical material |
| US20150133561A1 (en) * | 2013-11-12 | 2015-05-14 | Vizuri Health Sciences Llc | Aqueous based capsaicinoid formulations and methods of manufacture and use |
| KR20160002256A (ko) * | 2014-06-30 | 2016-01-07 | (주)메디톡스 | 가교된 히알루론난을 유효성분으로 포함하는 골관절염 치료용 약제학적 조성물 및 그를 이용한 골관절염 치료 방법 |
| KR102357341B1 (ko) * | 2014-11-06 | 2022-02-03 | 주식회사 엘지생활건강 | 숙지황 추출물을 포함하는 히알루론산 생성 촉진용 조성물과 이의 이용 |
| KR101521411B1 (ko) * | 2015-02-05 | 2015-05-19 | 박재우 | 뼈 및 연골을 포함한 관절질환 치료용 조성물 및 이의 제조방법 |
| ES2914684T3 (es) * | 2015-08-19 | 2022-06-15 | Univ Iowa Res Found | Terapia preventiva para la artrosis postraumática |
| KR101637883B1 (ko) * | 2015-09-30 | 2016-07-21 | 선바이오(주) | 폴리에틸렌글리콜 수화젤 주사제 |
| KR101895950B1 (ko) * | 2015-12-18 | 2018-09-06 | (주)한국비엠아이 | 골관절염 치료를 위한 친수화된 설파살라진 및 히알루론산을 포함하는 조성물 및 이의제조방법 |
| EP3597199A4 (en) | 2017-03-14 | 2021-01-20 | Seikagaku Corporation | JOINT DISEASE TREATMENT COMPOSITION AND KIT WITH IT |
| TW202027794A (zh) | 2018-10-03 | 2020-08-01 | 瑞士商諾華公司 | 血管生成素樣３多肽之持續遞送 |
| FR3105729B1 (fr) * | 2019-12-31 | 2023-07-21 | Mrs Biotech | Composition pour la gestion du poids d’un sujet |
| CN115444840B (zh) * | 2022-09-15 | 2023-08-25 | 四川大学 | 一种前药、两性离子水凝胶及其制备方法、应用 |
Family Cites Families (22)
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| JPS61210034A (ja) | 1985-03-15 | 1986-09-18 | Seikagaku Kogyo Co Ltd | 関節症治療剤 |
| US5356883A (en) | 1989-08-01 | 1994-10-18 | Research Foundation Of State University Of N.Y. | Water-insoluble derivatives of hyaluronic acid and their methods of preparation and use |
| JPH0574571A (ja) | 1990-12-25 | 1993-03-26 | Ricoh Co Ltd | 電界発光素子 |
| JP2855307B2 (ja) * | 1992-02-05 | 1999-02-10 | 生化学工業株式会社 | 光反応性グリコサミノグリカン、架橋グリコサミノグリカン及びそれらの製造方法 |
| US6025444A (en) | 1994-11-17 | 2000-02-15 | Seikagaku Kogyo Kabushiki Kaisha (Seikagaku Corporation) | Cinnamic acid derivative |
| JP3343181B2 (ja) * | 1995-09-20 | 2002-11-11 | 生化学工業株式会社 | 桂皮酸誘導体 |
| US5690961A (en) * | 1994-12-22 | 1997-11-25 | Hercules Incorporated | Acidic polysaccharides crosslinked with polycarboxylic acids and their uses |
| JP3955107B2 (ja) * | 1995-05-01 | 2007-08-08 | 生化学工業株式会社 | 架橋多糖の製造法 |
| HU224697B1 (en) * | 1995-11-15 | 2006-01-30 | Seikagaku Kogyo Co Ltd | Photocured cross-linked-hyaluronic acid gel and method of preparation thereof |
| DE69822285T2 (de) | 1998-02-27 | 2005-01-27 | Stichting Hyppomedics | Verfahren zur Herstellung von vernetzter Hyaluronsäure |
| ITPD980169A1 (it) | 1998-07-06 | 2000-01-06 | Fidia Advanced Biopolymers Srl | Ammidi dell'acido ialuronico e dei suoi derivati e processo per la loro preparazione. |
| WO2001057093A1 (en) * | 2000-02-03 | 2001-08-09 | Denki Kagaku Kogyo Kabushiki Kaisha | Hyaluronic acid gel, process for producing the same, and medical material containing the same |
| JP4172176B2 (ja) * | 2000-12-19 | 2008-10-29 | 生化学工業株式会社 | 光反応性ヒアルロン酸およびその製造方法ならびに光架橋ヒアルロン酸および医用材料 |
| DE60117502T2 (de) | 2000-12-19 | 2006-08-24 | Seikagaku Corp. | Photohärtbare Derivate von Hyaluronsäure, Verfahren zu deren Herstellung, vernetztes und photogehärtetes Derivat der Hyaluronsäure und diese enthaltendes medizinisches Material |
| JP4990446B2 (ja) | 2001-05-28 | 2012-08-01 | 電気化学工業株式会社 | 関節症治療用注入剤 |
| JP4958368B2 (ja) | 2002-02-28 | 2012-06-20 | 電気化学工業株式会社 | 架橋ヒアルロン酸 |
| AU2005283282B2 (en) | 2004-09-15 | 2011-05-19 | Seikagaku Corporation | Photoreactive polysaccharide, photocrosslinked polysaccharide products, the method of making them and medical materials therefrom |
| CA2590159C (en) | 2004-12-30 | 2011-07-12 | Genzyme Corporation | Regimens for intra-articular viscosupplementation |
| RU2429018C2 (ru) | 2005-07-06 | 2011-09-20 | Сейкагаку Корпорейшн | Гель, полученный из фотосшитой гиалуроновой кислоты с введенным лекарственным средством |
| ES2616295T3 (es) | 2005-10-12 | 2017-06-12 | Seikagaku Corporation | Agente para aplicar a mucosa y procedimiento para la producción del mismo |
| WO2008069348A1 (en) * | 2006-12-06 | 2008-06-12 | Seikagaku Corporation | Pharmaceutical agent having long-lasting effect of treating arthritic disorders |
| JO3008B1 (ar) | 2009-08-13 | 2016-09-05 | Seikagaku Kogyo Co Ltd | تركيب صيدلي لتخفيف الألم |
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- 2007-12-06 US US12/448,064 patent/US8889652B2/en active Active
- 2007-12-06 AU AU2007328871A patent/AU2007328871B2/en active Active
- 2007-12-06 TW TW096146443A patent/TWI419697B/zh active
- 2007-12-06 EP EP15154293.3A patent/EP2910248A1/en not_active Withdrawn
- 2007-12-06 JP JP2009524032A patent/JP5291621B2/ja active Active
- 2007-12-06 KR KR1020097014014A patent/KR101460815B1/ko not_active Expired - Fee Related
- 2007-12-06 CN CN201310232886.8A patent/CN103356694B/zh not_active Expired - Fee Related
-
2013
- 2013-06-07 JP JP2013120712A patent/JP5600192B2/ja active Active
-
2014
- 2014-08-14 JP JP2014165127A patent/JP5889976B2/ja active Active
- 2014-10-08 US US14/509,736 patent/US9616087B2/en active Active
- 2014-11-10 US US14/537,464 patent/US9301972B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP5291621B2 (ja) | 2013-09-18 |
| JP2013209417A (ja) | 2013-10-10 |
| US20110053885A1 (en) | 2011-03-03 |
| WO2008069348A9 (en) | 2009-08-20 |
| EP2094280A1 (en) | 2009-09-02 |
| CA2672002C (en) | 2015-06-02 |
| US20150094280A1 (en) | 2015-04-02 |
| US8889652B2 (en) | 2014-11-18 |
| EP2386306A1 (en) | 2011-11-16 |
| CN101573123A (zh) | 2009-11-04 |
| CN101573123B (zh) | 2013-06-05 |
| TWI419697B (zh) | 2013-12-21 |
| CA2672002A1 (en) | 2008-06-12 |
| HK1135923A1 (en) | 2010-06-18 |
| CN103356694A (zh) | 2013-10-23 |
| HK1185556A1 (en) | 2014-02-21 |
| KR101460815B1 (ko) | 2014-11-12 |
| US9301972B2 (en) | 2016-04-05 |
| AU2007328871B2 (en) | 2013-11-21 |
| JP5889976B2 (ja) | 2016-03-22 |
| AU2007328871A1 (en) | 2008-06-12 |
| TW201414479A (zh) | 2014-04-16 |
| KR20090087496A (ko) | 2009-08-17 |
| WO2008069348A1 (en) | 2008-06-12 |
| TW200831113A (en) | 2008-08-01 |
| US9616087B2 (en) | 2017-04-11 |
| US20150283169A1 (en) | 2015-10-08 |
| EP2910248A1 (en) | 2015-08-26 |
| JP2014237704A (ja) | 2014-12-18 |
| CN103356694B (zh) | 2015-09-02 |
| JP2010511596A (ja) | 2010-04-15 |
| JP5600192B2 (ja) | 2014-10-01 |
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