TWI444188B - 雜環化合物 - Google Patents

Info

Publication number

TWI444188B

TWI444188B TW097142682A TW97142682A TWI444188B TW I444188 B TWI444188 B TW I444188B TW 097142682 A TW097142682 A TW 097142682A TW 97142682 A TW97142682 A TW 97142682A TW I444188 B TWI444188 B TW I444188B

Authority

TW

Taiwan

Prior art keywords

compound

group

alkyl

preparation

solution

Prior art date

2008-04-21

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• 238000002360 preparation method Methods 0.000 claims description 161
• 125000000217 alkyl group Chemical group 0.000 claims description 62
• 125000000592 heterocycloalkyl group Chemical group 0.000 claims description 60
• 125000001072 heteroaryl group Chemical group 0.000 claims description 59
• 125000002947 alkylene group Chemical group 0.000 claims description 57
• 125000003118 aryl group Chemical group 0.000 claims description 52
• 125000000753 cycloalkyl group Chemical group 0.000 claims description 48
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• 125000004432 carbon atom Chemical group C* 0.000 claims description 26
• 229910052739 hydrogen Inorganic materials 0.000 claims description 26
• 229910052760 oxygen Inorganic materials 0.000 claims description 23
• 229910052736 halogen Inorganic materials 0.000 claims description 21
• 150000002367 halogens Chemical class 0.000 claims description 21
• 229910052757 nitrogen Inorganic materials 0.000 claims description 20
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• 125000005842 heteroatom Chemical group 0.000 claims description 19
• 229910052717 sulfur Inorganic materials 0.000 claims description 18
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• 101000922348 Homo sapiens C-X-C chemokine receptor type 4 Proteins 0.000 claims description 13
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