TWI417096B - 用於發炎及免疫相關用途之苯基及吡啶基化合物 - Google Patents

用於發炎及免疫相關用途之苯基及吡啶基化合物 Download PDF

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TWI417096B
TWI417096B TW096102797A TW96102797A TWI417096B TW I417096 B TWI417096 B TW I417096B TW 096102797 A TW096102797 A TW 096102797A TW 96102797 A TW96102797 A TW 96102797A TW I417096 B TWI417096 B TW I417096B
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optionally substituted
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methyl
alkyl
phenyl
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TW096102797A
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TW200744592A (en
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Jun Jiang
Junyi Zhang
Nha Huu Vo
Shoujun Chen
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Synta Pharmaceuticals Corp
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    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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TW096102797A 2006-01-25 2007-01-25 用於發炎及免疫相關用途之苯基及吡啶基化合物 TWI417096B (zh)

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US76201506P 2006-01-25 2006-01-25
US76193106P 2006-01-25 2006-01-25

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TW200744592A TW200744592A (en) 2007-12-16
TWI417096B true TWI417096B (zh) 2013-12-01

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US (1) US20070275960A1 (https=)
EP (1) EP1983831A4 (https=)
JP (1) JP2009524678A (https=)
AU (1) AU2007208227A1 (https=)
CA (1) CA2639913A1 (https=)
TW (1) TWI417096B (https=)
WO (1) WO2007087429A2 (https=)

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WO2007087442A2 (en) * 2006-01-25 2007-08-02 Synta Pharmaceuticals Corp. Substituted biaryl compounds for inflammation and immune-related uses
WO2007087441A2 (en) * 2006-01-25 2007-08-02 Synta Pharmaceuticals Corp. Substituted aromatic compounds for inflammation and immune-related uses
CA2639910A1 (en) * 2006-01-25 2007-08-02 Synta Pharmaceuticals Corp. Thiazole and thiadiazole compounds for inflammation and immune-related uses
WO2007087443A2 (en) 2006-01-25 2007-08-02 Synta Pharmaceuticals Corp. Vinyl-phenyl derivatives for inflammation and immune-related uses
US8119643B2 (en) * 2006-03-20 2012-02-21 Synta Pharmaceuticals Corp. Benzoimidazolyl-pyrazine compounds for inflammation and immune-related uses
JP2010501567A (ja) 2006-08-24 2010-01-21 ノバルティス アクチエンゲゼルシャフト 代謝系、心血管系および他の障害の処置のためのステアロイル−CoA不飽和化酵素(SCD)阻害剤としての2−(ピラジン−2−イル)−チアゾールおよび2−(1H−ピラゾール−3−イル)チアゾール誘導体ならびに関連化合物
KR20090053923A (ko) 2006-09-22 2009-05-28 노파르티스 아게 헤테로시클릭 유기 화합물
US8779154B2 (en) * 2006-09-26 2014-07-15 Qinglin Che Fused ring compounds for inflammation and immune-related uses
CN101595105B (zh) 2006-12-20 2013-01-23 诺瓦提斯公司 作为scd抑制剂的2-取代的5元杂环化合物
AR067354A1 (es) 2007-06-29 2009-10-07 Sunesis Pharmaceuticals Inc Compuestos utiles como inhibidores de la raf quinasa
EP2184994B1 (en) * 2007-08-01 2013-09-25 Synta Pharmaceuticals Corp. Heterocycle-aryl compounds for inflammation and immune-related uses
JP5411141B2 (ja) 2007-09-10 2014-02-12 カルシメディカ,インク. 細胞内カルシウムを調節する化合物
US8389567B2 (en) 2007-12-12 2013-03-05 Calcimedica, Inc. Compounds that modulate intracellular calcium
UA103319C2 (en) 2008-05-06 2013-10-10 Глаксосмитклайн Ллк Thiazole- and oxazole-benzene sulfonamide compounds
EP2307421A4 (en) 2008-06-30 2011-07-13 Cylene Pharmaceuticals Inc oxindole
US7906553B2 (en) 2008-08-27 2011-03-15 Calcimedica, Inc. Substituted thiophene modulators of intracellular calcium
US8524763B2 (en) 2008-09-22 2013-09-03 Calcimedica, Inc. Inhibitors of store operated calcium release
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