TWI370741B - Stable liquid compositions for treating stomatitis comprising epidermal growth factor - Google Patents
Stable liquid compositions for treating stomatitis comprising epidermal growth factorInfo
- Publication number
- TWI370741B TWI370741B TW096137828A TW96137828A TWI370741B TW I370741 B TWI370741 B TW I370741B TW 096137828 A TW096137828 A TW 096137828A TW 96137828 A TW96137828 A TW 96137828A TW I370741 B TWI370741 B TW I370741B
- Authority
- TW
- Taiwan
- Prior art keywords
- growth factor
- epidermal growth
- liquid compositions
- stable liquid
- treating stomatitis
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1808—Epidermal growth factor [EGF] urogastrone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/485—Epidermal growth factor [EGF] (urogastrone)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1020060097734A KR100784134B1 (ko) | 2006-10-09 | 2006-10-09 | 상피세포성장인자를 함유하는 안정한 구내염 치료용 액상조성물 |
Publications (2)
Publication Number | Publication Date |
---|---|
TW200824719A TW200824719A (en) | 2008-06-16 |
TWI370741B true TWI370741B (en) | 2012-08-21 |
Family
ID=39140442
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TW096137828A TWI370741B (en) | 2006-10-09 | 2007-10-09 | Stable liquid compositions for treating stomatitis comprising epidermal growth factor |
Country Status (8)
Country | Link |
---|---|
US (1) | US9155697B2 (zh) |
EP (1) | EP2083797A4 (zh) |
JP (1) | JP2010505942A (zh) |
KR (1) | KR100784134B1 (zh) |
CN (1) | CN101541305B (zh) |
MY (1) | MY144321A (zh) |
TW (1) | TWI370741B (zh) |
WO (1) | WO2008044852A1 (zh) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20100190735A1 (en) * | 2006-03-28 | 2010-07-29 | Myrex Pharmaceuticals Inc. | Mouthwash and Method of Using Same for the Treatment of Mucositis or Stomatitis |
US8221994B2 (en) * | 2009-09-30 | 2012-07-17 | Cilag Gmbh International | Adhesive composition for use in an immunosensor |
AU2012202981B2 (en) * | 2009-09-30 | 2014-01-23 | Cilag Gmbh International | Adhesive Composition for Use in an Immunosensor |
WO2015077227A1 (en) | 2013-11-19 | 2015-05-28 | Aqua Metals Inc. | Devices and methods for smelterless recycling of lead acid batteries |
EP3294929B1 (en) | 2015-05-13 | 2021-04-14 | Aqua Metals Inc. | Closed loop systems and methods for recycling lead acid batteries |
US10689769B2 (en) | 2015-05-13 | 2020-06-23 | Aqua Metals Inc. | Electrodeposited lead composition, methods of production, and uses |
KR102274210B1 (ko) | 2015-05-13 | 2021-07-06 | 아쿠아 메탈스 인크. | 납산 배터리로부터 납의 회수를 위한 시스템 및 방법들 |
US10316420B2 (en) | 2015-12-02 | 2019-06-11 | Aqua Metals Inc. | Systems and methods for continuous alkaline lead acid battery recycling |
JP7183268B2 (ja) * | 2017-11-20 | 2022-12-05 | ジャスト-エヴォテック バイオロジックス、インコーポレイテッド | 等張化剤としてリジン塩を含有するアフリベルセプト製剤及びその使用 |
Family Cites Families (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4717717A (en) | 1986-11-05 | 1988-01-05 | Ethicon, Inc. | Stabilized compositions containing epidermal growth factor |
NZ235556A (en) | 1986-11-05 | 1991-06-25 | Ethicon Inc | Breast milk substitute containing recombinant human egf |
NZ226171A (en) * | 1987-09-18 | 1990-06-26 | Ethicon Inc | Gel formulation containing polypeptide growth factor |
US5705485A (en) * | 1987-09-18 | 1998-01-06 | Ethicon, Inc. | Gel formulations containing growth factors |
US5102870A (en) | 1989-04-14 | 1992-04-07 | Schering Ag | Treatment and prevention of oral mucositis with growth factors |
US5130298A (en) * | 1989-05-16 | 1992-07-14 | Ethicon, Inc. | Stabilized compositions containing epidermal growth factor |
US5272135A (en) * | 1991-03-01 | 1993-12-21 | Chiron Ophthalmics, Inc. | Method for the stabilization of methionine-containing polypeptides |
EP0648113A4 (en) | 1992-04-23 | 1996-12-04 | Berlex Lab | BIOADHAESIVE FIXED MINERAL OIL EMULSION. |
KR960013439B1 (ko) | 1993-04-26 | 1996-10-05 | 주식회사 대웅제약 | 안정한 상피세포 성장인자(egf) 조성물 |
SE9400036D0 (sv) | 1994-01-10 | 1994-01-10 | Pharmacia Ab | Low modecular weight hyaluronic acid |
US5580856A (en) | 1994-07-15 | 1996-12-03 | Prestrelski; Steven J. | Formulation of a reconstituted protein, and method and kit for the production thereof |
TW518219B (en) * | 1996-04-26 | 2003-01-21 | Chugai Pharmaceutical Co Ltd | Erythropoietin solution preparation |
WO1999009992A1 (fr) * | 1997-08-27 | 1999-03-04 | Yoshitomi Pharmaceutical Industries, Ltd. | Promoteurs de neovascularisation |
JP2001526239A (ja) | 1997-12-22 | 2001-12-18 | ヒューマン・ジェノム・サイエンシズ・インコーポレイテッド | 角質細胞増殖因子−2製剤 |
JP2000056344A (ja) * | 1998-06-05 | 2000-02-25 | Fuji Xerox Co Ltd | 光導波路素子およびその製造方法 |
WO2000056344A1 (fr) | 1999-03-24 | 2000-09-28 | Seikagaku Corporation | Salive artificielle |
US6458387B1 (en) * | 1999-10-18 | 2002-10-01 | Epic Therapeutics, Inc. | Sustained release microspheres |
AU1979201A (en) * | 1999-12-09 | 2001-06-18 | Bio Syntech Canada Inc | Mineral-polymer hybrid composition |
KR100366439B1 (ko) | 2000-02-21 | 2003-01-09 | 주식회사 대웅 | 상피세포 성장인자를 유효성분으로 하는 안정한 약제학적조성물 |
JP5058404B2 (ja) * | 2000-07-03 | 2012-10-24 | 株式会社シリウス | スロットマシン |
US7998929B2 (en) | 2000-09-01 | 2011-08-16 | Chugai Seikyaku Kabushiki Kaisha | Solution preparations stabilized over long time |
US7544348B2 (en) | 2001-02-15 | 2009-06-09 | Access Pharmaceuticals, Inc. | Liquid formulations for the prevention and treatment of mucosal diseases and disorders |
JP2002255852A (ja) * | 2001-03-01 | 2002-09-11 | Toa Eiyo Ltd | 口内炎用スプレー製剤 |
CN1129452C (zh) | 2001-04-10 | 2003-12-03 | 王非 | 表皮生长因子口含片 |
US7202066B2 (en) | 2002-01-29 | 2007-04-10 | Carrington Laboratories, Inc. | Combination of a growth factor and a protease enzyme |
WO2004028557A1 (ja) | 2002-09-26 | 2004-04-08 | Shionogi & Co., Ltd. | 安定化されたタンパク組成物 |
US20060193783A1 (en) | 2003-02-17 | 2006-08-31 | Bhowmick Balaram S | Low dose corticosteroid composition |
EP1532983A1 (en) * | 2003-11-18 | 2005-05-25 | ZLB Bioplasma AG | Immunoglobulin preparations having increased stability |
KR20050055858A (ko) | 2003-12-09 | 2005-06-14 | 주식회사 엘지생활건강 | 구강 약물 전달 시스템 |
FI20041425A0 (fi) | 2004-11-05 | 2004-11-05 | Orion Corp | Transmukosaalinen veterinäärinen koostumus |
ES2504441T3 (es) * | 2004-12-15 | 2014-10-08 | Swedish Orphan Biovitrum Ab (Publ) | Formulaciones terapéuticas del factor de crecimiento de queratinocitos |
SG161209A1 (en) | 2004-12-22 | 2010-05-27 | Ambrx Inc | Formulations of human growth hormone comprising a non-naturally encoded amino acid |
CA2600836A1 (en) * | 2005-03-08 | 2006-09-14 | Pharmacia & Upjohn Company Llc | Composition comprising an antibody against macrophage colony-stimulating factor (m-csf) and a chelating agent |
WO2008088922A2 (en) * | 2007-01-19 | 2008-07-24 | Genentech, Inc. | Prevention of hydrogel viscosity loss |
-
2006
- 2006-10-09 KR KR1020060097734A patent/KR100784134B1/ko active IP Right Grant
-
2007
- 2007-10-09 MY MYPI20091421A patent/MY144321A/en unknown
- 2007-10-09 TW TW096137828A patent/TWI370741B/zh active
- 2007-10-09 CN CN2007800437524A patent/CN101541305B/zh active Active
- 2007-10-09 WO PCT/KR2007/004911 patent/WO2008044852A1/en active Application Filing
- 2007-10-09 JP JP2009532289A patent/JP2010505942A/ja active Pending
- 2007-10-09 EP EP07833222A patent/EP2083797A4/en not_active Withdrawn
- 2007-10-09 US US12/444,961 patent/US9155697B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
EP2083797A4 (en) | 2012-10-31 |
CN101541305A (zh) | 2009-09-23 |
US20100035809A1 (en) | 2010-02-11 |
JP2010505942A (ja) | 2010-02-25 |
EP2083797A1 (en) | 2009-08-05 |
WO2008044852A1 (en) | 2008-04-17 |
TW200824719A (en) | 2008-06-16 |
MY144321A (en) | 2011-08-29 |
CN101541305B (zh) | 2012-04-11 |
KR100784134B1 (ko) | 2007-12-12 |
US9155697B2 (en) | 2015-10-13 |
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