TWI369981B - Hmb compositions and uses thereof - Google Patents

Hmb compositions and uses thereof

Info

Publication number
TWI369981B
TWI369981B TW094109357A TW94109357A TWI369981B TW I369981 B TWI369981 B TW I369981B TW 094109357 A TW094109357 A TW 094109357A TW 94109357 A TW94109357 A TW 94109357A TW I369981 B TWI369981 B TW I369981B
Authority
TW
Taiwan
Prior art keywords
hmb
compositions
hmb compositions
Prior art date
Application number
TW094109357A
Other languages
English (en)
Chinese (zh)
Other versions
TW200539860A (en
Inventor
Jeffrey H Baxter
Anne C Voss
Pradip Mukerji
Michael J Tisdale
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of TW200539860A publication Critical patent/TW200539860A/zh
Application granted granted Critical
Publication of TWI369981B publication Critical patent/TWI369981B/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Molecular Biology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Child & Adolescent Psychology (AREA)
  • Urology & Nephrology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Dermatology (AREA)
  • Nutrition Science (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pulmonology (AREA)
  • AIDS & HIV (AREA)
TW094109357A 2004-03-26 2005-03-25 Hmb compositions and uses thereof TWI369981B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10/810,762 US20050215640A1 (en) 2004-03-26 2004-03-26 HMB compositions and uses thereof

Publications (2)

Publication Number Publication Date
TW200539860A TW200539860A (en) 2005-12-16
TWI369981B true TWI369981B (en) 2012-08-11

Family

ID=34990887

Family Applications (1)

Application Number Title Priority Date Filing Date
TW094109357A TWI369981B (en) 2004-03-26 2005-03-25 Hmb compositions and uses thereof

Country Status (14)

Country Link
US (9) US20050215640A1 (enExample)
EP (3) EP1727534A2 (enExample)
JP (3) JP5145033B2 (enExample)
KR (2) KR20130010912A (enExample)
CN (1) CN101212961A (enExample)
AU (1) AU2005235133B2 (enExample)
BR (1) BRPI0509017A (enExample)
CA (2) CA2807787C (enExample)
EC (1) ECSP066873A (enExample)
ES (2) ES2586402T3 (enExample)
IL (1) IL178039A0 (enExample)
MX (1) MXPA06010922A (enExample)
TW (1) TWI369981B (enExample)
WO (1) WO2005102301A2 (enExample)

Families Citing this family (107)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050215640A1 (en) 2004-03-26 2005-09-29 Baxter Jeffrey H HMB compositions and uses thereof
PL371081A1 (pl) * 2004-11-08 2006-05-15 Sgp & Sons Ab Preparat farmaceutyczny wpływający na procesy wzrostu i mineralizacji układu kostno-szkieletowego oraz chorób kości i chrząstki wieku dojrzałego u ludzi i zwierząt oraz zastosowanie preparatu farmaceutycznego w procesie wzrostu i mineralizacji układu kostno-szkieletowego oraz chorób kości i chrząstki wieku dojrzałego u ludzi i zwierząt
ES2548432T3 (es) * 2005-12-19 2015-10-16 Abbott Laboratories Uso de beta-hidroxi-beta-metilbutirato para modular el desequilibrio en la producción de citoquinas de tipo 1 y tipo 2
US9358242B2 (en) * 2007-08-30 2016-06-07 Prelief Inc. Calcium glycerophosphate for treating and preventing respiratory diseases or conditions
US9770424B2 (en) 2008-12-09 2017-09-26 Metabolic Technologies, Inc. Nutritional intervention for improving muscular function and strength
US9707241B2 (en) 2008-12-09 2017-07-18 Metabolic Technologies, Inc. Nutritional intervention for improving muscular function and strength
US9259430B2 (en) 2008-12-09 2016-02-16 Metabolic Technologies, Inc. Nutritional intervention for improving muscular function and strength
ES2689700T3 (es) * 2008-12-09 2018-11-15 Metabolic Technologies, Inc. Intervención nutricional para mejorar la función y resistencia muscular
US11173167B2 (en) 2008-12-09 2021-11-16 Metabolic Technologies, Inc. Nutritional intervention for improving muscular function and strength
US9539224B2 (en) 2008-12-09 2017-01-10 Metabolic Technologies, Inc. Nutritional intervention for improving muscular function and strength
WO2010098822A1 (en) 2009-02-24 2010-09-02 Ritter Pharmaceuticals, Inc. Prebiotic formulations and methods of use
CN102458109B (zh) 2009-04-29 2015-02-11 阿马里纳制药公司 稳定的药物组合物和使用其的方法
MX2011011517A (es) 2009-04-29 2012-06-19 Amarin Corp Plc Composiciones farmaceuticas que comprenden epa y un agente cardiovascular y metodos para utilizar el mismo.
LT2443246T (lt) 2009-06-15 2018-03-26 Amarin Pharmaceuticals Ireland Limited Kompozicijos ir būdai, skirti trigliceridų sumažinimui, nepakeliant ldl-c lygio subjekte, kartu taikant statino terapiją
US20110071176A1 (en) 2009-09-23 2011-03-24 Amarin Pharma, Inc. Pharmaceutical composition comprising omega-3 fatty acid and hydroxy-derivative of a statin and methods of using same
CN101704736A (zh) * 2009-10-30 2010-05-12 黄再新 β-羟基-β-甲基丁酸生产过程中氯气逸出时的应急处理方法
US8490829B2 (en) 2009-11-24 2013-07-23 Pepsico, Inc. Personalized beverage dispensing device
US8335592B2 (en) 2009-11-24 2012-12-18 Pepsico, Inc. Beverage dispensing device
US9754437B2 (en) * 2009-11-24 2017-09-05 Pepsico, Inc. Automated beverage formulation
EP2512236B1 (en) * 2009-12-18 2016-10-19 Metabolic Technologies, Inc. Improved method of administering beta-hydroxy-beta-methylbutyrate (hmb)
US9693577B2 (en) 2010-01-29 2017-07-04 Abbott Laboratories Method of preparing a nutritional powder comprising spray dried HMB
EP2528457B1 (en) * 2010-01-29 2015-01-14 Abbott Laboratories Plastic packaged nutritonal liquids comprising hmb
PE20121730A1 (es) * 2010-01-29 2013-01-13 Abbott Lab Liquidos nutricionales envasados asepticamente que comprenden beta-hidroxi-beta-metilbutirato (hmb)
WO2011094549A1 (en) * 2010-01-29 2011-08-04 Abbott Laboratories Nutritional powders comprising spray dried hmb
MX340405B (es) * 2010-01-29 2016-07-07 Abbott Lab Emulsiones nutricionales que comprenden beta-hidroxi-beta-metilbut irato (hmb) de calcio y proteina soluble.
MX2012008785A (es) * 2010-01-29 2012-08-17 Abbott Lab Emulsiones nutricionales que comprenden beta-hidroxi-beta-metilbut irato (hmb) de calcio.
EP3202406A1 (en) 2010-04-28 2017-08-09 Ritter Pharmaceuticals, Inc. Prebiotic formulations and methods of use
TWI526161B (zh) * 2010-06-10 2016-03-21 亞培公司 包含鈣ｈｍｂ及可溶性蛋白質之實質上透明營養液
EP2444083A1 (en) 2010-10-21 2012-04-25 Nestec S.A. Cysteine and food intake
AU2011336856A1 (en) 2010-11-29 2013-07-04 Amarin Pharmaceuticals Ireland Limited Low eructation composition and methods for treating and/or preventing cardiovascular disease in a subject with fish allergy/hypersensitivity
US11712429B2 (en) 2010-11-29 2023-08-01 Amarin Pharmaceuticals Ireland Limited Low eructation composition and methods for treating and/or preventing cardiovascular disease in a subject with fish allergy/hypersensitivity
MX2013007347A (es) * 2010-12-22 2013-08-01 Abbott Lab Productos nutricionales que comprenden beta-hidroxi-beta metilbutirato de calcio y acido linoleico conjugado.
CA2821312A1 (en) * 2010-12-27 2012-07-05 Abbott Laboratories Methods for facilitating muscle recovery after a period of disuse using beta-hydroxy-beta-methylbutyrate
ES2689225T3 (es) * 2011-02-07 2018-11-12 Abbott Laboratories Productos nutricionales que comprenden beta-hidroxi-beta-metilbutirato
US8951514B2 (en) 2011-02-16 2015-02-10 Pivotal Therapeutics Inc. Statin and omega 3 fatty acids for reduction of apolipoprotein-B levels
US8715648B2 (en) 2011-02-16 2014-05-06 Pivotal Therapeutics Inc. Method for treating obesity with anti-obesity formulations and omega 3 fatty acids for the reduction of body weight in cardiovascular disease patients (CVD) and diabetics
US9119826B2 (en) 2011-02-16 2015-09-01 Pivotal Therapeutics, Inc. Omega 3 fatty acid for use as a prescription medical food and omega 3 fatty acid diagniostic assay for the dietary management of cardiovascular patients with cardiovascular disease (CVD) who are deficient in blood EPA and DHA levels
US8952000B2 (en) 2011-02-16 2015-02-10 Pivotal Therapeutics Inc. Cholesterol absorption inhibitor and omega 3 fatty acids for the reduction of cholesterol and for the prevention or reduction of cardiovascular, cardiac and vascular events
EP2675298A1 (en) 2011-02-17 2013-12-25 Abbott Laboratories Methods for improving brain development and cognitive function using beta-hydroxy-beta-methylbutyrate
BR112013025047A2 (pt) * 2011-03-31 2017-02-14 Nestec Sa composições nutricionais para aumentar os níveis de arginina e métodos para usar as mesmas
US8183227B1 (en) 2011-07-07 2012-05-22 Chemo S. A. France Compositions, kits and methods for nutrition supplementation
CA2846041A1 (en) * 2011-08-15 2013-02-21 Yao-En Li Process for manufacturing hmb and salts thereof
US8168611B1 (en) 2011-09-29 2012-05-01 Chemo S.A. France Compositions, kits and methods for nutrition supplementation
US11291643B2 (en) 2011-11-07 2022-04-05 Amarin Pharmaceuticals Ireland Limited Methods of treating hypertriglyceridemia
US20130131170A1 (en) 2011-11-07 2013-05-23 Amarin Pharmaceuticals Ireland Limited Methods of treating hypertriglyceridemia
WO2013103958A1 (en) 2012-01-06 2013-07-11 Amarin Pharmaceuticals Ireland Limited Compositions and methods for lowering levels of high-sensitivity (hs-crp) in a subject
ES2421187B1 (es) * 2012-02-23 2014-11-26 Abbott Laboratories Metodo para mejorar el desarrollo cerebral y la funcion cognitiva usando beta-hidroxi-beta-metilbutirato
US20150119339A1 (en) * 2012-06-11 2015-04-30 Abbott Laboratories Use of hmb to improve health outcomes for hospitalized patients
BR112014032905B1 (pt) 2012-06-29 2022-02-22 Amarin Pharmaceuticals Ireland Limited Uso de éster etílico do ácido eicosapentaenóico para redução do risco de morte cardiovascular, revascularização coronária e/ou angina instável em um indivíduo em terapia com estatina
US20140037813A1 (en) * 2012-08-02 2014-02-06 Mead Johnson Nutrition Company Nutritional creamer composition
JP6258943B2 (ja) * 2012-09-10 2018-01-10 メタボリック・テクノロジーズ，インコーポレーテッド Ｈｍｂおよびａｔｐの組成物ならびに使用方法
EP2895013A1 (en) * 2012-09-17 2015-07-22 Abbott Laboratories Beta-hydroxy-beta-methylbutryic acid- containing compositions and uses thereof
JP6346896B2 (ja) * 2012-09-21 2018-06-20 アボット・ラボラトリーズＡｂｂｏｔｔ Ｌａｂｏｒａｔｏｒｉｅｓ カルシウムβ−ヒドロキシ−β−メチルブチレート、タンパク質および低レベルの電解質を含む栄養組成物
US20150265566A1 (en) 2012-11-06 2015-09-24 Amarin Pharmaceuticals Ireland Limited Compositions and Methods for Lowering Triglycerides without Raising LDL-C Levels in a Subject on Concomitant Statin Therapy
US20140187633A1 (en) 2012-12-31 2014-07-03 Amarin Pharmaceuticals Ireland Limited Methods of treating or preventing nonalcoholic steatohepatitis and/or primary biliary cirrhosis
WO2014113404A1 (en) 2013-01-15 2014-07-24 Nusirt Sciences, Inc. Treating pulmonary conditions
US9452151B2 (en) 2013-02-06 2016-09-27 Amarin Pharmaceuticals Ireland Limited Methods of reducing apolipoprotein C-III
US9624492B2 (en) 2013-02-13 2017-04-18 Amarin Pharmaceuticals Ireland Limited Compositions comprising eicosapentaenoic acid and mipomersen and methods of use thereof
US9820504B2 (en) 2013-03-08 2017-11-21 Axiom Foods, Inc. Rice protein supplement and methods of use thereof
BR112015020977A2 (pt) 2013-03-08 2017-07-18 Axiom Foods Inc suplemento de proteína de arroz e métodos de uso do mesmo
CN105188695A (zh) 2013-03-14 2015-12-23 雅培制药有限公司 与长期体力活动不足有关的胰岛素抗性的治疗
US20140271841A1 (en) 2013-03-15 2014-09-18 Amarin Pharmaceuticals Ireland Limited Pharmaceutical composition comprising eicosapentaenoic acid and derivatives thereof and a statin
US10966968B2 (en) 2013-06-06 2021-04-06 Amarin Pharmaceuticals Ireland Limited Co-administration of rosiglitazone and eicosapentaenoic acid or a derivative thereof
US20150057350A1 (en) * 2013-08-23 2015-02-26 Abbott Laboratories Fibrosis biomarkers and methods of using same
US20150065572A1 (en) 2013-09-04 2015-03-05 Amarin Pharmaceuticals Ireland Limited Methods of treating or preventing prostate cancer
US9585859B2 (en) 2013-10-10 2017-03-07 Amarin Pharmaceuticals Ireland Limited Compositions and methods for lowering triglycerides without raising LDL-C levels in a subject on concomitant statin therapy
JP6349575B2 (ja) * 2013-12-03 2018-07-04 小林香料株式会社 Ｈｍｂを含有する酸性飲料
WO2015094767A1 (en) * 2013-12-18 2015-06-25 Abbott Laboratories Methods for maintaining or increasing bodyweight using decaffeinated green tea extract
WO2015094925A1 (en) 2013-12-18 2015-06-25 Capsugel Belgium Nv Stable liquid filled hard capsule comprising beta-hydroxy-beta-methylbutyric acid
WO2015105981A2 (en) * 2014-01-09 2015-07-16 Abbott Laboratories Conditional essentiality of hmb
JP6480964B2 (ja) * 2014-03-14 2019-03-13 メタボリック・テクノロジーズ，インコーポレーテッド 遊離酸形のβ−ヒドロキシ−β−メチル酪酸（ＨＭＢ）を含有する液体及び食品ならびにその製造法
US10561631B2 (en) 2014-06-11 2020-02-18 Amarin Pharmaceuticals Ireland Limited Methods of reducing RLP-C
US10172818B2 (en) 2014-06-16 2019-01-08 Amarin Pharmaceuticals Ireland Limited Methods of reducing or preventing oxidation of small dense LDL or membrane polyunsaturated fatty acids
US20160184248A1 (en) * 2014-12-15 2016-06-30 University Of Central Florida Research Foundation Inc. Compositions and methods of use of -hydroxy-methylbutyrate (hmb) resulting in an acute endocrine response
EP3302704B1 (en) * 2015-06-01 2023-01-25 Metabolic Technologies, Inc. Compositions and methods of use of beta-hydroxy-beta-methylbutyrate (hmb) for decreasing fat mass
US10758504B2 (en) 2015-09-16 2020-09-01 Metabolic Technologies, Inc. Compositions and methods of use of β-hydroxy-β-methylbutyrate (HMB) for enhancing recovery from soft tissue trauma
US12208073B2 (en) 2015-09-16 2025-01-28 Metabolic Technologies, LLC Compositions and methods of use of beta-hydroxy-beta-methylbutyrate (HMB) for enhancing recovery from soft tissue trauma
WO2017123922A1 (en) * 2016-01-13 2017-07-20 Metabolic Technologies, Inc. COMPOSITIONS AND METHODS OF USE OF β-HYDROXY-β-METHYLBUTYRATE (HMB) FOR JOINT STABILITY
BR112018014920A2 (pt) * 2016-01-21 2018-12-18 Metabolic Tech Inc métodos de autofagia por modulação, de tratamento ou redução da probabilidade do início de uma condição mediada por autofagia, de tratamento, inibição, redução, diminuição, ou prevenção de um distúrbio relacionado à idade, de modulação da expressão ou atividade de pelo menos um fator de transcrição, de tratamento, prevenção, diminuição, inibição ou redução de uma condição patológica atribuível a um estado de excesso de nutriente, de promoção de longevidade por autofagia por modulação, de aumento da duração de tempo que um mamífero pode levar um estilo de vida ativo sem sofrer de condições associadas com envelhecimento e de prolongamento do período de saúde de um mamífero.
US11406609B2 (en) 2016-01-21 2022-08-09 Metabolic Technologies, Inc. Compositions and methods of use of β-hydroxy-β-methylbutyrate (HMB) for modulating autophagy and lipophagy
US10406130B2 (en) 2016-03-15 2019-09-10 Amarin Pharmaceuticals Ireland Limited Methods of reducing or preventing oxidation of small dense LDL or membrane polyunsaturated fatty acids
MX2018014407A (es) 2016-05-25 2019-02-21 Tsi Group Ltd Estabilizacion de formulaciones de acido beta-hidroxiisovalerico en capsulas de gel blando.
JOP20190146A1 (ar) 2016-12-19 2019-06-18 Axcella Health Inc تركيبات حمض أميني وطرق لمعالجة أمراض الكبد
JP7136807B2 (ja) 2017-04-17 2022-09-13 ザ・ユニバーシティ・オブ・シカゴ ヒトの健康及び疾患の治療用途向けの短鎖脂肪酸の腸への送達用ポリマー材料
EP3634155A4 (en) 2017-05-12 2021-02-17 Axiom Foods Inc. RICE PRODUCTS AND SYSTEMS AND PROCESSES FOR THEIR PRODUCTION
WO2018213663A1 (en) 2017-05-19 2018-11-22 Amarin Pharmaceuticals Ireland Limited Compositions and methods for lowering triglycerides in a subject having reduced kidney function
MA49906A (fr) 2017-08-14 2020-06-24 Axcella Health Inc Acides aminés à chaîne ramifiée pour le traitement d'une maladie du foie
US11058661B2 (en) 2018-03-02 2021-07-13 Amarin Pharmaceuticals Ireland Limited Compositions and methods for lowering triglycerides in a subject on concomitant statin therapy and having hsCRP levels of at least about 2 mg/L
CN108558707A (zh) * 2018-04-13 2018-09-21 太仓运通新材料科技有限公司 一种三肌酸hmb盐的制备方法
AU2019261476B2 (en) * 2018-04-25 2021-11-18 Oncocross Co.,Ltd. Composition for preventing and treating muscular disease
EP3810123A1 (en) 2018-06-20 2021-04-28 Axcella Health Inc. Compositions and methods for the treatment of fat infiltration in muscle
IL261670B (en) * 2018-09-06 2019-06-30 Tudu Holdings Ltd A preparation that includes magnesium and its uses
MA51766A (fr) 2018-09-24 2020-12-16 Amarin Pharmaceuticals Ie Ltd Procédés de réduction du risque d'événements cardiovasculaires chez un sujet
US10888576B2 (en) 2018-10-08 2021-01-12 Metabolic Technologies, Inc. Composition of HMB and ATP and methods of use
JP7286964B2 (ja) * 2018-12-28 2023-06-06 日油株式会社 β－ヒドロキシ－β－メチル酪酸、タンパク質、及び液状油脂を含有する液状栄養組成物
CN111714616A (zh) * 2019-07-17 2020-09-29 江苏西宏生物医药有限公司 一种用于抗肿瘤的组合物
JP7594356B2 (ja) * 2019-10-30 2024-12-04 小林製薬株式会社 経口組成物
CN114980973A (zh) 2019-11-12 2022-08-30 阿马里纳药物爱尔兰有限公司 降低心房纤颤和/或心房扑动受试者心血管事件风险的方法
CA3171034A1 (en) * 2020-03-12 2021-09-16 Suzette Pereira Methods of treating diarrhea or inflammatory conditions of the gut
CN116600660A (zh) * 2020-06-17 2023-08-15 代谢科技有限责任公司 在未锻炼下改善肌肉量、力量和肌肉功能的β-羟基-β-甲基丁酸(HMB)的组合物和使用方法
EP4236945A1 (en) * 2020-10-30 2023-09-06 Société des Produits Nestlé S.A. Compositions containing nicotinamide and vitamin b6 and methods of using such compositions for promoting muscle growth
US20230398104A1 (en) * 2020-10-30 2023-12-14 Societe Des Produits Nestle S.A. Compositions containing nicotinamide and vitamin b6 and methods of using such compositions for rehabilitation
BR112023004232A2 (pt) * 2020-10-30 2023-05-09 Nestle Sa Composições contendo nicotinamida e vitamina b6 e métodos de uso de tais composições para tratar sarcopenia e debilidade
WO2022090457A1 (en) * 2020-10-30 2022-05-05 Société des Produits Nestlé S.A. Compositions containing nicotinamide and vitamin b6 and methods of using such compositions for treating cachexia or precachexia
AU2022263358A1 (en) 2021-04-21 2023-11-30 Amarin Pharmaceuticals Ireland Limited Methods of reducing the risk of heart failure
WO2023031226A1 (en) * 2021-08-31 2023-03-09 INSERM (Institut National de la Santé et de la Recherche Médicale) Use of branched chain fatty acids (bcfas) for the treatment of intestinal inflammation
DE202023107635U1 (de) * 2023-12-22 2024-02-08 RenaCare NEPHROMED GmbH Zusammensetzung zur Eiweißsubstitution

Family Cites Families (128)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US597650A (en) 1898-01-18 morris
US3408210A (en) * 1965-06-14 1968-10-29 Wilbert A. Heyman Dehydration of foods
US3542560A (en) * 1967-12-06 1970-11-24 American Home Prod Infant formula with fat composition like human milk
GB1446965A (en) * 1974-02-14 1976-08-18 Agricultural Vegetable Prod Preparation of food products
US4104290A (en) * 1975-02-07 1978-08-01 H.L.S. Ltd., Industrial Engineering Company Process for separating oils and fats into liquid and solid fractions
US4311645A (en) 1980-03-24 1982-01-19 Hoffmann-La Roche Inc. Synthesis of SRS-active compounds
US4871768A (en) 1984-07-12 1989-10-03 New England Deaconess Hospital Corporation Dietary supplement utilizing ω-3/medium chain trigylceride mixtures
US4866040A (en) * 1986-01-06 1989-09-12 Alfred Stracher Aminocarnitine directed pharmaceutical agents
US4742081A (en) * 1986-01-06 1988-05-03 Alfred Stracher Carnitine coupled pharmaceutical agents
DE3620433A1 (de) 1986-06-18 1987-12-23 Boehringer Ingelheim Kg Verwendung von 2-(n-2,6-dichlorphenyl-n-allyl-amino)-imidazolin-(2) als cytoprotektives mittel
ES2052066T3 (es) 1988-10-31 1994-07-01 Sandoz Nutrition Ltd Mejoras en o relacionadas con compuestos organicos.
US5000975A (en) * 1988-12-29 1991-03-19 American Home Products Corporation Randomized palm oil fat composition for infant formulas
CA2010511A1 (en) 1989-03-01 1990-09-01 Roberto L. Ceriani Method of enhancing cancer therapy by administration of unsaturated fatty acids
GB8906369D0 (en) * 1989-03-20 1989-05-04 Tisdale Michael J Eicosapentaenoic acid
US5457130A (en) * 1989-03-20 1995-10-10 Cancer Research Campaign Technology Limited Eicosapentaenoic acid used to treat cachexia
US5157022A (en) 1989-11-22 1992-10-20 Adrian Barbul Method for reducing blood cholesterol using arginine
US5028440A (en) * 1990-01-30 1991-07-02 Iowa State University Research Foundation, Inc. Method of raising meat producing animals to increase lean tissue development
US5087472A (en) * 1990-01-30 1992-02-11 Iowa State University Research Foundation, Inc. Feed compositions for domestics animals containing hydroxymethylbutyrate
US4992470A (en) * 1990-02-08 1991-02-12 Iowa State University Research Foundation, Inc. Method of enhancing immune response of mammals
US5167957A (en) * 1990-09-06 1992-12-01 Virginia Tech Intellectual Properties, Inc. Compositions and methods for the treatment of dietary deficiencies
US5601860A (en) * 1990-11-30 1997-02-11 American Home Products Corporation Corandomized fat compositions for infant formulas
FR2674102B1 (fr) 1991-03-18 1994-05-20 Meiji Seika Kaisha Ltd Aliment pour porcs et methode d'elevage des porcs utilisant cet aliment.
US5085883A (en) 1991-06-27 1992-02-04 Abbott Laboratories Blend of dietary fiber for nutritional products
US5171442A (en) * 1991-10-18 1992-12-15 Nakshbendi Ghassan F Water purification apparatus
US5223285A (en) * 1992-03-31 1993-06-29 Abbott Laboratories Nutritional product for pulmonary patients
NZ256300A (en) * 1992-09-16 1997-06-24 Univ Iowa State Res Found Inc Administration of beta-hydroxy-beta-methyl butyric acid, or its convertible forms, to lower cholesterol levels
US5447732A (en) 1992-11-25 1995-09-05 Ajinomoto Co., Inc. High-absorption mineral-containing composition and foods
US5348979A (en) 1992-12-23 1994-09-20 Iowa State University Research Foundation Inc. Method of promoting nitrogen retention in humans
JP2761294B2 (ja) 1993-05-13 1998-06-04 ロデルス−クロクラーン エステル交換トリグリセリドブレンド由来のヒト母乳脂肪代用品
US6136858A (en) * 1994-01-10 2000-10-24 Abbott Laboratories Infant formula and methods of improving infant stool patterns
US5952314A (en) * 1994-04-01 1999-09-14 Demichele; Stephen Joseph Nutritional product for a person having ulcerative colitis
US5444054A (en) * 1994-04-01 1995-08-22 Abbott Labatories Method of treating ulcerative colitis
US5780451A (en) * 1994-04-01 1998-07-14 Abbott Laboratories Nutritional product for a person having ulcerative colitis
US5576287A (en) * 1994-04-29 1996-11-19 Wake Forest University Method for treating acute renal disease and failure
US5726146A (en) * 1994-12-06 1998-03-10 Natural Supplement Association, Incorporated Non-steroidal, anabolic dietary supplement and method to increase lean mass without linked increase fat mass
KR0140248B1 (ko) 1995-03-23 1998-06-15 한상기 신규한 카제인 포스포펩티드, 그것을 포함하는 카제인 및 그 제조방법
DE19528461A1 (de) * 1995-08-03 1997-02-06 Braun Melsungen Ag Präparat zur Ernährung
US5641531A (en) 1995-09-28 1997-06-24 Abbott Laboratories Nutritional liquid supplement beverage and method of making same
CN1086282C (zh) 1995-12-15 2002-06-19 普罗克特和甘保尔公司 含有多磷酸盐防腐剂体系和少量黄原胶的,具有稳定的风味乳浊液/混浊乳浊液的饮料
WO1997037546A1 (en) * 1996-04-11 1997-10-16 Loders Croklaan B.V. Free flowing fat compositions
US6077828A (en) * 1996-04-25 2000-06-20 Abbott Laboratories Method for the prevention and treatment of cachexia and anorexia
US5756469A (en) 1996-07-26 1998-05-26 Beale; Paxton K. Composition of pyruvate and anti-cortisol compounds and method for increasing protein concentration in a mammal
US7504376B2 (en) * 1996-08-12 2009-03-17 Natural Alternatives International Methods and compositions for increasing the anaerobic working capacity in tissues
US6080788A (en) * 1997-03-27 2000-06-27 Sole; Michael J. Composition for improvement of cellular nutrition and mitochondrial energetics
DE29707308U1 (de) 1997-04-23 1997-06-26 Kunz, Armin, 66450 Bexbach Präparat zur Muskelerhaltung bzw. zur Förderung des Muskelaufbaus
US6660258B1 (en) * 1997-05-09 2003-12-09 Pharma Pacific Pty Ltd Oromucosal cytokine compositions and uses thereof
US6103764A (en) * 1997-11-07 2000-08-15 Iowa State University Research Foundation, Inc. Method for increasing the aerobic capacity of muscle
US6013665A (en) 1997-12-16 2000-01-11 Abbott Laboratories Method for enhancing the absorption and transport of lipid soluble compounds using structured glycerides
US6194379B1 (en) 1998-05-01 2001-02-27 Abbott Laboratories Elemental enteral formula
US6475539B1 (en) 1998-05-07 2002-11-05 Abbott Laboratories Nutritionally complete low pH enteral formula
JP4175698B2 (ja) * 1998-06-19 2008-11-05 サントリー株式会社 新規なトリグリセリド及びそれを含む組成物
US6031000A (en) * 1998-06-23 2000-02-29 Iowa State University Research Foundation, Inc. Composition comprising β-hydroxy-β-methylbutyric acid and at least one amino acid and methods of use
JP4703851B2 (ja) * 1998-07-30 2011-06-15 シグマ−タウ・インドゥストリエ・ファルマチェウチケ・リウニテ・ソシエタ・ペル・アチオニ Ｌ−カルニチンおよびそのアルカノイル誘導体の、抗癌作用を有する医薬品の製造のための使用
US5976550A (en) * 1998-11-20 1999-11-02 Engel; Peter H. Dietary food supplement
US20010008641A1 (en) * 1998-11-25 2001-07-19 R. Douglas Krotzer Nutritionally active composition for bodybuilding
JP3973786B2 (ja) 1998-12-28 2007-09-12 松下電器産業株式会社 スパッタリング方法及び装置
US6294206B1 (en) * 1999-04-09 2001-09-25 Abbott Laboratories Powdered human milk fortifier
US6291525B1 (en) * 1999-09-08 2001-09-18 Iowa State University Research Foundation, Inc. Method for improving a human's perception of his emotional state
JP2003511094A (ja) * 1999-10-18 2003-03-25 マッスルテク リサーチ アンド ディヴェロプメント インコーポレーション 無脂肪体重及び体力を増強するための食物補充物質
GB9929919D0 (en) 1999-12-17 2000-02-09 Hannah Research Inst The Calcium phosphate nanoclusters and their applications
US6521591B1 (en) * 2000-02-10 2003-02-18 N.V. Nutricia Pharmaceutical composition for muscular anabolism
US7250397B2 (en) * 2000-02-23 2007-07-31 Zealand Pharma A/S Antiarrhythmic peptides
WO2001077271A2 (en) 2000-04-06 2001-10-18 Conlinco, Inc. Conjugated linoleic acid compositions
JP4625156B2 (ja) * 2000-04-10 2011-02-02 イーエヌ大塚製薬株式会社 癌化学療法に伴う副作用軽減剤
US6420342B1 (en) * 2000-05-08 2002-07-16 N.V. Nutricia Nutritional preparation comprising ribose and medical use thereof
US20050106219A1 (en) * 2000-05-30 2005-05-19 Karlheinz Bortlik Primary composition comprising a lipophilic bioactive compound
AU2001279129A1 (en) 2000-08-03 2002-02-18 North Carolina State University Enhancement of development of oviparous species by in ovo feeding
US20030176514A1 (en) 2000-08-29 2003-09-18 Martin Fuhrmann Method for preparing a mixture that can be granulated and carnitine-magnesium hydroxycitrate
US20030203070A1 (en) * 2000-09-26 2003-10-30 The Procter & Gamble Company Compositions containing sorbitan monoesters
EP1198991B1 (en) * 2000-10-20 2012-12-19 Nutriz N.V: Non-dairy products derived from rice
US20030165604A1 (en) * 2001-02-15 2003-09-04 Kazufumi Tsubaki Products containing $g(b)-glucan
JP3735070B2 (ja) * 2001-03-26 2006-01-11 花王株式会社 容器詰乳化飲料
US6620427B2 (en) * 2001-04-24 2003-09-16 Abbott Laboratories Method for improving bone mineralization
US20030021877A1 (en) * 2001-06-13 2003-01-30 Cain Frederick William Micronised fat particles
DE10145818C1 (de) * 2001-09-17 2002-10-10 Alfill Engineering Gmbh & Co K Sterilisiervorrichtung mit H202-Verdampfer
JP2003137790A (ja) * 2001-11-01 2003-05-14 Mie Kariyou Kk β−２，１（β２→β１）結合連鎖フラクトースオリゴマーを含有するフラクトオリゴ糖を有効成分とする医薬
GB2381451A (en) * 2001-11-01 2003-05-07 New Technology Res Ltd Pharmaco-dietary preparation having nutrition-supplementing and nutrition-enhancing effect
EP2261312A1 (en) * 2001-12-12 2010-12-15 Martek Biosciences Corporation Extraction and Winterization of Lipids from Oilseed and Microbial Sources
DE10163676A1 (de) 2001-12-21 2003-07-10 Phenion Gmbh & Co Kg Verwendung von Hyperforin oder Extrakten aus Johanniskraut gegen anaphylaktische Schockzustände oder Osteoporose
US7168581B2 (en) * 2001-12-21 2007-01-30 Rexam Medical Packaging Inc. Closure for a retort processed container having a peelable seal
US20030165579A1 (en) 2002-02-27 2003-09-04 Chih-Hui Lin Euphorbia antiquorum extract, a pharmaceutical composition containing the same and methods for treatment of cancers
DE60313769T2 (de) 2002-04-23 2008-03-06 Aventis Pharmaceuticals Inc. 3-(pyridinyl-amino)-1h-indol-2-carbonsäure-verbindungen als inhibitoren der interleukin-4 genexpression
SE0201581D0 (sv) * 2002-05-29 2002-05-29 Scandinavian Biotechnology Res New improved acyltransferase
WO2004002232A1 (en) * 2002-06-28 2004-01-08 Theuer Richard C Fat compositions for infant formula and methods therefor
US20040048925A1 (en) * 2002-09-09 2004-03-11 Wiley David B. Composition and method for enhancing the bioavailability of calcium and magnesium in dietary supplements and food additives
US20040106678A1 (en) * 2002-09-17 2004-06-03 Dobbins Thomas A Compositions for the parenteral administration of calcium and magnesium
US7411039B2 (en) * 2002-10-14 2008-08-12 Novo Nordisk A/S GLP-2 compounds, formulations, and uses thereof
US7445807B2 (en) * 2002-10-15 2008-11-04 Western Holdings, Llc Agglomerated granular protein-rich nutritional supplement
GB0301554D0 (en) 2003-01-23 2003-02-26 Molecularnature Ltd Immunostimulatory compositions
US7332178B2 (en) * 2003-04-25 2008-02-19 Abbott Laboratories Stable nutritional powder containing ascorbyl palmitate
FR2856596B1 (fr) 2003-06-27 2007-04-27 Bioprojet Soc Civ Nouvelle association medicamenteuse psychiatrique et utilisation d'une antagoniste ou agoniste inverse du recepteur h3 de l'histamine pour preparer un medicament prevenant des effets indesirables de psychotropes.
AU2004279621A1 (en) * 2003-10-14 2005-04-21 The Provost, Fellows And Scholars Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth Near Dublin Adenylate cyclase in the treatment and/or prophylaxis of immune-medicated disease
IL158555A0 (en) * 2003-10-22 2004-05-12 Enzymotec Ltd Human breast milk lipid mimetic as dietary supplement
WO2005060952A1 (en) * 2003-12-24 2005-07-07 N.V. Nutricia Compositions comprising pantothenic acid or derivatives thereof and their use for stimulating appetite
US7696241B2 (en) 2004-03-04 2010-04-13 Bristol-Myers Squibb Company Bicyclic compounds as modulators of androgen receptor function and method
US20050215640A1 (en) 2004-03-26 2005-09-29 Baxter Jeffrey H HMB compositions and uses thereof
US20050249650A1 (en) * 2004-05-07 2005-11-10 Fmc Technologies, Inc. Immersion retort
PT1799052E (pt) * 2004-09-09 2011-01-20 Nestec Sa Métodos para o fabrico de produtos nutricionais com qualidade melhorada
WO2006031699A2 (en) * 2004-09-10 2006-03-23 Diversa Corporation Compositions and methods for making and modifying oils
PL371081A1 (pl) 2004-11-08 2006-05-15 Sgp & Sons Ab Preparat farmaceutyczny wpływający na procesy wzrostu i mineralizacji układu kostno-szkieletowego oraz chorób kości i chrząstki wieku dojrzałego u ludzi i zwierząt oraz zastosowanie preparatu farmaceutycznego w procesie wzrostu i mineralizacji układu kostno-szkieletowego oraz chorób kości i chrząstki wieku dojrzałego u ludzi i zwierząt
US8067052B2 (en) * 2005-02-25 2011-11-29 Siddharth Shastri Nutritional composition and a container for the convenient transport and storage of the nutritional composition
CA2537452C (en) * 2005-03-09 2013-12-24 Abbott Laboratories Concentrated human milk fortifier liquid
KR20130136013A (ko) * 2005-04-27 2013-12-11 엔지모테크 리미티드 모유 지방 대체물
KR20080015071A (ko) * 2005-06-06 2008-02-18 브리스톨-마이어스스퀴브컴파니 저-피테이트 유아용 조제유
MX2008002701A (es) 2005-08-26 2008-03-18 Nestec Sa Nutricion para pacientes obesos.
MY147363A (en) * 2005-09-20 2012-11-30 Nestec Sa Water dispersible composition and method for preparing same
US20090182050A1 (en) 2005-10-07 2009-07-16 Ocean Nutrition Canada, Ltd. Salts of Fatty Acids and Methods of Making and Using thereof
WO2007056176A2 (en) * 2005-11-03 2007-05-18 Southwest Immunology, Inc. Compositions for preventing and reducing delayed onset muscle soreness
ES2548432T3 (es) 2005-12-19 2015-10-16 Abbott Laboratories Uso de beta-hidroxi-beta-metilbutirato para modular el desequilibrio en la producción de citoquinas de tipo 1 y tipo 2
ATE475328T1 (de) * 2006-01-31 2010-08-15 Nestec Sa Nährstoffzusammensetzung für säuglinge mit niedrigem geburtsgewicht
US20080119552A1 (en) * 2006-11-17 2008-05-22 Novus International Inc. Matrix-embedded compositions having organic acids and fatty acids
US20080194407A1 (en) 2007-02-14 2008-08-14 Ashmead H Dewayne High nitrogen containing chelate compositions suitable for plant delivery
US20090110674A1 (en) 2007-10-24 2009-04-30 Loizou Nicos C Health supplement
CA2649477C (en) * 2008-04-18 2016-04-19 Nuvocare Health Sciences Inc. Composition and method for promoting internal health and external appearance
WO2009143097A1 (en) 2008-05-21 2009-11-26 Stokely-Van Camp, Inc. Milk-based recovery beverage
ES2689700T3 (es) * 2008-12-09 2018-11-15 Metabolic Technologies, Inc. Intervención nutricional para mejorar la función y resistencia muscular
JP2009155336A (ja) 2009-03-31 2009-07-16 Tsujido Chemical Corp 治療剤
US20090312419A1 (en) 2009-08-12 2009-12-17 Kneller Bruce W CREATINE -ßALANINATE: A NOVEL SALT FOR INCREASING ATHLETIC PERFORMANCE
PL217815B1 (pl) 2009-12-14 2014-08-29 Olimp Lab Spółka Z Ograniczoną Odpowiedzialnością Napój izotoniczny z chelatami
CN101785566A (zh) 2010-01-22 2010-07-28 北京康比特体育科技股份有限公司 一种含有hmb的运动饮料
MX2012008785A (es) 2010-01-29 2012-08-17 Abbott Lab Emulsiones nutricionales que comprenden beta-hidroxi-beta-metilbut irato (hmb) de calcio.
TWI526161B (zh) 2010-06-10 2016-03-21 亞培公司 包含鈣ｈｍｂ及可溶性蛋白質之實質上透明營養液
US10869843B2 (en) 2010-11-23 2020-12-22 Chemi Nutra Method for increasing muscle mass and strength
CA2821312A1 (en) 2010-12-27 2012-07-05 Abbott Laboratories Methods for facilitating muscle recovery after a period of disuse using beta-hydroxy-beta-methylbutyrate
WO2012097061A1 (en) 2011-01-13 2012-07-19 Abbott Laboratories Nutritional compositions and methods for improving skeletal muscle protein metabolism
TW201320908A (zh) 2011-10-13 2013-06-01 Abbott Lab 包含β－丙胺酸之營養產品
WO2013170189A1 (en) 2012-05-11 2013-11-14 Abbott Laboratories Combination of beta - hydroxy - beta - methylbutyrate and beta - alanine for increasing muscle blood flow
US20150119339A1 (en) 2012-06-11 2015-04-30 Abbott Laboratories Use of hmb to improve health outcomes for hospitalized patients

Also Published As

Publication number Publication date
ES2699161T3 (es) 2019-02-07
EP2301529A1 (en) 2011-03-30
US8778993B2 (en) 2014-07-15
EP2444082B1 (en) 2018-09-12
US20120177752A1 (en) 2012-07-12
CA2560042C (en) 2014-02-11
US20050215640A1 (en) 2005-09-29
US8785496B2 (en) 2014-07-22
US20070093553A1 (en) 2007-04-26
MXPA06010922A (es) 2006-12-15
WO2005102301A2 (en) 2005-11-03
TW200539860A (en) 2005-12-16
JP5145033B2 (ja) 2013-02-13
AU2005235133A1 (en) 2005-11-03
US20130011498A1 (en) 2013-01-10
EP1727534A2 (en) 2006-12-06
US20120189714A1 (en) 2012-07-26
CA2807787A1 (en) 2005-11-03
KR20130010912A (ko) 2013-01-29
US8778994B2 (en) 2014-07-15
EP2301529B1 (en) 2016-07-20
JP2015147773A (ja) 2015-08-20
KR101253063B1 (ko) 2013-04-11
ECSP066873A (es) 2006-11-24
EP2444082A3 (en) 2012-08-01
US20120189715A1 (en) 2012-07-26
IL178039A0 (en) 2007-07-04
AU2005235133B2 (en) 2010-06-17
HK1155972A1 (en) 2012-06-01
US8609725B2 (en) 2013-12-17
US20120189717A1 (en) 2012-07-26
US8217077B2 (en) 2012-07-10
EP2444082A2 (en) 2012-04-25
CN101212961A (zh) 2008-07-02
JP5732437B2 (ja) 2015-06-10
ES2586402T3 (es) 2016-10-14
US20120189716A1 (en) 2012-07-26
BRPI0509017A (pt) 2007-08-07
CA2807787C (en) 2014-08-12
CA2560042A1 (en) 2005-11-03
JP2007530542A (ja) 2007-11-01
US8785495B2 (en) 2014-07-22
KR20060134181A (ko) 2006-12-27
US20120196829A1 (en) 2012-08-02
WO2005102301A3 (en) 2006-10-26
JP2012229227A (ja) 2012-11-22

Similar Documents

Publication Publication Date Title
TWI369981B (en) Hmb compositions and uses thereof
GB0422525D0 (en) Dermatological compositions and methods
IL183581A0 (en) Viscosupplementation devices and compositions
ZA200704295B (en) Arthrospira-based compositions and uses thereof
EP1802588A4 (en) SUBSTITUTED AMINOPYRIMIDONE AND APPLICATIONS THEREOF
PL2218342T3 (pl) Nowe kompozycje nutraceutyczne i ich zastosowanie
IL180762A (en) Oligomer-insulin conjugates, formulations containing them and their use
GB0411940D0 (en) Methods and compositions
IL191072A0 (en) Therapeutic compositions and methods
EP1701725A4 (en) PROCESS AND COMPOSITIONS
IL183986A0 (en) Pharmaceutical compounds and compositions
IL182126A (en) Preparations containing and used in the history of 5-phenoxyalkoxypsoralen
EP1890677A4 (en) PHARMACEUTICAL COMPOSITIONS AND THEIR USE
ZA200706128B (en) Pesticide compositions and methods
IL179497A0 (en) Carboranylporphyrins and uses thereof
EP1807071A4 (en) ANTIPYRETIC METHODS AND COMPOSITIONS
IL186337A0 (en) Stannsoporfin compositions and administration
IL180365A0 (en) Carboranylporphyrins and uses thereof
GB0424051D0 (en) Compounds and compositions
GB0325942D0 (en) Compositions and uses thereof
GB0501348D0 (en) Compositions and methods
EP1865777A4 (en) STANNSOPORFIN COMPOSITIONS AND ADMINISTRATION
ZA200610727B (en) Compositions comprising strontium and vitamin D and uses thereof
GB0309509D0 (en) Pharmaceutical compositions and their uses
GB0428034D0 (en) Compositions and methods

Legal Events

Date Code Title Description
MM4A Annulment or lapse of patent due to non-payment of fees