TWI365754B - Glutathione based delivery system - Google Patents
Glutathione based delivery systemInfo
- Publication number
- TWI365754B TWI365754B TW094147661A TW94147661A TWI365754B TW I365754 B TWI365754 B TW I365754B TW 094147661 A TW094147661 A TW 094147661A TW 94147661 A TW94147661 A TW 94147661A TW I365754 B TWI365754 B TW I365754B
- Authority
- TW
- Taiwan
- Prior art keywords
- delivery system
- based delivery
- glutathione based
- glutathione
- delivery
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/06—Tripeptides
- A61K38/063—Glutathione
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6905—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion
- A61K47/6911—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion the form being a liposome
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/70—Nanostructure
- Y10S977/773—Nanoparticle, i.e. structure having three dimensions of 100 nm or less
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Dispersion Chemistry (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Neurosurgery (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Pain & Pain Management (AREA)
- Toxicology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Polyethers (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12/244,563 US8067380B2 (en) | 2005-12-19 | 2008-10-02 | Glutathione-based delivery system |
US13/287,480 US8673863B2 (en) | 2005-12-19 | 2011-11-02 | Glutathione-based delivery system |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11/303,934 US7446096B2 (en) | 2005-12-19 | 2005-12-19 | Glutathione based delivery system |
Publications (1)
Publication Number | Publication Date |
---|---|
TWI365754B true TWI365754B (en) | 2012-06-11 |
Family
ID=36217526
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TW094147661A TWI365754B (en) | 2005-12-19 | 2005-12-30 | Glutathione based delivery system |
Country Status (11)
Country | Link |
---|---|
US (4) | US7446096B2 (zh) |
EP (2) | EP2837384A1 (zh) |
JP (2) | JP4773200B2 (zh) |
CN (2) | CN1985804B (zh) |
CY (1) | CY1115542T1 (zh) |
DK (1) | DK1891962T3 (zh) |
ES (1) | ES2516665T3 (zh) |
PL (1) | PL1891962T3 (zh) |
PT (1) | PT1891962E (zh) |
SI (1) | SI1891962T1 (zh) |
TW (1) | TWI365754B (zh) |
Families Citing this family (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AUPR549901A0 (en) * | 2001-06-06 | 2001-07-12 | Vital Health Sciences Pty Ltd | Topical formulation containing tocopheryl phosphates |
AU2002950713A0 (en) | 2002-08-09 | 2002-09-12 | Vital Health Sciences Pty Ltd | Carrier |
US20040057983A1 (en) | 2002-09-25 | 2004-03-25 | David Schmidt | Biomolecular wearable apparatus |
RU2477136C2 (ru) * | 2004-03-03 | 2013-03-10 | Вайтал Хэлф Сайнсис Пти Лтд | Алкалоидные составы |
MX2007001356A (es) * | 2004-08-03 | 2007-04-23 | Vital Health Sciences Pty Ltd | Portador para administracion enterica. |
US20090239827A1 (en) * | 2005-03-03 | 2009-09-24 | Esra Ogru | Compounds having lipid lowering properties |
EP2548581A3 (en) | 2005-06-17 | 2013-02-20 | Vital Health Sciences Pty Ltd. | A carrier comprising one or more di and/or mono-(electron transfer agent) phosphate derivatives or complexes thereof |
US7446096B2 (en) * | 2005-12-19 | 2008-11-04 | Industrial Technology Research Institute | Glutathione based delivery system |
US8067380B2 (en) * | 2005-12-19 | 2011-11-29 | Industrial Technology Research Institute | Glutathione-based delivery system |
DK2308514T3 (da) * | 2007-03-23 | 2013-09-02 | To Bbb Holding B V | Konjugater til målrettet lægemiddeltransport gennem blod-hjerne barrieren |
FR2926725B1 (fr) * | 2008-01-25 | 2010-09-03 | Biochimie Appliquee Soc | Compositions cosmetiques et/ou dermatologiques cicatrisantes |
US8602961B2 (en) | 2008-05-15 | 2013-12-10 | Lifewave Products Llc | Apparatus and method of stimulating elevation of glutathione levels in a subject |
EP2610343A3 (en) | 2008-11-26 | 2013-09-25 | Chugai Seiyaku Kabushiki Kaisha | Method for designing siRNA and oligoribonucleotides inhibiting HCV |
JP5600299B2 (ja) * | 2008-11-26 | 2014-10-01 | 中外製薬株式会社 | ベシクル製剤 |
PT3395372T (pt) * | 2009-02-20 | 2022-05-05 | Enhanx Biopharm Inc | Sistema de entrega de medicamentos à base de glutationa |
EP2531047A4 (en) | 2010-02-05 | 2014-03-19 | Phosphagenics Ltd | CARRIER WITH AN UNINUTRALIZED TOCOPHERYL PHOSPHATE |
AU2011235597B2 (en) * | 2010-03-30 | 2015-07-16 | Phosphagenics Limited | Transdermal delivery patch |
US9561243B2 (en) | 2011-03-15 | 2017-02-07 | Phosphagenics Limited | Composition comprising non-neutralised tocol phosphate and a vitamin A compound |
GB201302427D0 (en) * | 2013-02-12 | 2013-03-27 | Midatech Ltd | Nanoparticle delivery compositions |
US20150093399A1 (en) | 2013-08-28 | 2015-04-02 | Bioasis Technologies, Inc. | Cns-targeted conjugates having modified fc regions and methods of use thereof |
KR102256576B1 (ko) | 2013-10-08 | 2021-05-27 | 에이아이 테라퓨틱스, 인코포레이티드 | 림프관평활근종증의 치료를 위한 라파마이신 |
US10765755B1 (en) * | 2013-11-20 | 2020-09-08 | University Of South Florida | Preparation and characterization of methylene blue nanoparticles for Alzheimer's disease and other tauopathies |
PL3125875T3 (pl) | 2014-04-04 | 2023-11-20 | AI Therapeutics, Inc. | Nadający się do inhalacji preparat rapamycyny do leczenia stanów związanych z wiekiem |
WO2015154897A1 (en) * | 2014-04-08 | 2015-10-15 | Wolfgang Stremmel | Means and methods for treating disorders of copper metabolism |
EP3131944B1 (en) * | 2014-04-17 | 2018-12-05 | The Corporation OF Mercer University | Vitamin e-based nanocarriers for drug delivery and methods of making and using the same |
WO2016057712A1 (en) | 2014-10-07 | 2016-04-14 | Lam Therapeutics, Inc. | An inhalable rapamycin formulation for the treatment of pulmonary hypertension |
US10758520B1 (en) | 2015-05-20 | 2020-09-01 | University Of South Florida | Glutathione-coated nanoparticles for delivery of MKT-077 across the blood-brain barrier |
CN108601732A (zh) | 2015-12-09 | 2018-09-28 | 磷肌酸有限公司 | 药物制剂 |
WO2018112512A1 (en) | 2016-12-21 | 2018-06-28 | Phosphagenics Limited | Process |
US10226442B2 (en) | 2017-07-10 | 2019-03-12 | Syneurx International (Taiwan) Corp. | Lithium salts of N-substituted glycine compounds and uses thereof |
US10842755B2 (en) | 2018-03-23 | 2020-11-24 | University Of South Carolina | Nanoparticles for brain targeted drug delivery |
WO2021054927A2 (en) * | 2018-08-10 | 2021-03-25 | South Dakota Board Of Regents | Glutathione-cholesterol derivatives as brain targeting agents |
WO2020242217A1 (ko) * | 2019-05-28 | 2020-12-03 | 울산과학기술원 | 글루타치온-s-전이효소 및 표적 세포 또는 표적 단백질 결합능을 갖는 단백질을 포함하는 리포좀 및 이의 용도 |
EP3954393A1 (en) | 2020-08-13 | 2022-02-16 | Bioasis Technologies Inc. | Combination therapies for delivery across the blood brain barrier |
TW202228792A (zh) | 2020-10-09 | 2022-08-01 | 殷漢生技股份有限公司 | 吸入用奈米載體製劑 |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS60142915A (ja) | 1983-12-28 | 1985-07-29 | Lion Corp | 口腔用組成物 |
JPS632922A (ja) | 1986-06-20 | 1988-01-07 | Yamanouchi Pharmaceut Co Ltd | ドラツグキヤリア |
JPH0714865B2 (ja) * | 1986-10-28 | 1995-02-22 | 武田薬品工業株式会社 | リポソ−ム製剤およびその製造法 |
FR2627385B3 (fr) | 1988-02-23 | 1991-08-23 | Serobiologiques Lab Sa | Composition notamment utile comme matiere de base pour la preparation de compositions pharmaceutiques, notamment dermatologiques et/ou cosmetiques |
US5695751A (en) | 1993-04-08 | 1997-12-09 | Cornell Research Foundation, Inc. | Enhancing delivery of large neutral amino acid drugs |
JPH0834779A (ja) * | 1994-05-20 | 1996-02-06 | Senju Pharmaceut Co Ltd | トコフェロール誘導体 |
US6653331B2 (en) | 1996-07-03 | 2003-11-25 | Pharmacia & Upjohn Company | Targeted drug delivery using sulfonamide derivatives |
WO1998008490A1 (en) * | 1996-09-01 | 1998-03-05 | Pharmos Corporation | Solid coprecipitates for enhanced bioavailability of lipophilic substances |
WO1998016201A1 (en) * | 1996-10-11 | 1998-04-23 | Sequus Pharmaceuticals, Inc. | Therapeutic liposome composition and method |
US6228347B1 (en) | 1997-12-01 | 2001-05-08 | Thione International, Inc. | Antioxidant gel for gingival conditions |
AU766515B2 (en) | 1998-04-16 | 2003-10-16 | Teijin Limited | Glutathione derivatives and dosage forms thereof |
JP2004323486A (ja) * | 2003-04-30 | 2004-11-18 | National Institute Of Advanced Industrial & Technology | 網膜及び/又はブドウ膜疾患の予防乃至治療用点眼薬 |
CN100515390C (zh) * | 2005-04-14 | 2009-07-22 | 蔡海德 | 垂体前叶肾上腺皮质提取物纳米脂质体组合药物及其制备方法和用途 |
US8067380B2 (en) * | 2005-12-19 | 2011-11-29 | Industrial Technology Research Institute | Glutathione-based delivery system |
US7446096B2 (en) * | 2005-12-19 | 2008-11-04 | Industrial Technology Research Institute | Glutathione based delivery system |
-
2005
- 2005-12-19 US US11/303,934 patent/US7446096B2/en active Active
- 2005-12-27 JP JP2005374896A patent/JP4773200B2/ja active Active
- 2005-12-29 PT PT52928207T patent/PT1891962E/pt unknown
- 2005-12-29 EP EP14180310.6A patent/EP2837384A1/en not_active Ceased
- 2005-12-29 PL PL05292820T patent/PL1891962T3/pl unknown
- 2005-12-29 DK DK05292820.7T patent/DK1891962T3/da active
- 2005-12-29 SI SI200531880T patent/SI1891962T1/sl unknown
- 2005-12-29 EP EP05292820.7A patent/EP1891962B1/en active Active
- 2005-12-29 ES ES05292820.7T patent/ES2516665T3/es active Active
- 2005-12-30 TW TW094147661A patent/TWI365754B/zh active
-
2006
- 2006-01-19 CN CN200610005869.0A patent/CN1985804B/zh active Active
- 2006-01-19 CN CN2008101693581A patent/CN101385859B/zh active Active
-
2007
- 2007-12-11 US US12/000,261 patent/US7704956B2/en not_active Expired - Fee Related
-
2008
- 2008-11-03 US US12/263,885 patent/US7700564B2/en active Active
-
2010
- 2010-01-15 JP JP2010007125A patent/JP5394944B2/ja active Active
- 2010-03-11 US US12/721,633 patent/US8569239B2/en active Active
-
2014
- 2014-09-10 CY CY20141100728T patent/CY1115542T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
CN101385859B (zh) | 2011-12-07 |
EP1891962A1 (en) | 2008-02-27 |
US7704956B2 (en) | 2010-04-27 |
CN101385859A (zh) | 2009-03-18 |
DK1891962T3 (da) | 2014-10-13 |
EP1891962B1 (en) | 2014-08-13 |
JP2010150264A (ja) | 2010-07-08 |
PT1891962E (pt) | 2014-11-11 |
US20100166849A1 (en) | 2010-07-01 |
CN1985804B (zh) | 2014-05-14 |
US8569239B2 (en) | 2013-10-29 |
US20070141133A1 (en) | 2007-06-21 |
SI1891962T1 (sl) | 2014-12-31 |
JP2007169252A (ja) | 2007-07-05 |
PL1891962T3 (pl) | 2015-01-30 |
CY1115542T1 (el) | 2017-01-04 |
US7446096B2 (en) | 2008-11-04 |
CN1985804A (zh) | 2007-06-27 |
EP2837384A1 (en) | 2015-02-18 |
JP4773200B2 (ja) | 2011-09-14 |
US7700564B2 (en) | 2010-04-20 |
US20080095836A1 (en) | 2008-04-24 |
US20090060991A1 (en) | 2009-03-05 |
JP5394944B2 (ja) | 2014-01-22 |
ES2516665T3 (es) | 2014-10-31 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
TWI365754B (en) | Glutathione based delivery system | |
IL278979A (en) | Pharma-Informatics system | |
HK1113657A1 (zh) | 經頰遞送系統 | |
IL184824A0 (en) | Infusion delivery system | |
EP2061261A4 (en) | STEREO PROJECTION SYSTEM | |
GB0517035D0 (en) | Delivery system | |
EP1902360A4 (en) | SYSTEM FOR RELEASING CONTENT | |
GB2432827B (en) | Fragrance delivery system | |
ZA200804176B (en) | A delivery system | |
EP1891801A4 (en) | DOCUMENT DISTRIBUTION SYSTEM | |
GB2431563B (en) | Watersport hiking-support system | |
GB0511518D0 (en) | Nofog system | |
GB2433249B (en) | Pumping system | |
GB0504771D0 (en) | System | |
EP1857537A4 (en) | PUMPING SYSTEM FOR FLUIDS | |
GB0518674D0 (en) | System | |
GB2427760B (en) | Antenna-transceiver system | |
GB0519069D0 (en) | Delivery system | |
GB0525355D0 (en) | Delivery system | |
ZA200610015B (en) | Nutrient delivery system | |
GB2430017B (en) | Connection system | |
AU2005905750A0 (en) | Delivery system | |
AU2005902906A0 (en) | Delivery system | |
PL114959U1 (en) | Delivery system | |
GB0513683D0 (en) | Advanced parcel delivery system |