PT1891962E - Sistema de administração à base de glutationa - Google Patents

Sistema de administração à base de glutationa Download PDF

Info

Publication number
PT1891962E
PT1891962E PT52928207T PT05292820T PT1891962E PT 1891962 E PT1891962 E PT 1891962E PT 52928207 T PT52928207 T PT 52928207T PT 05292820 T PT05292820 T PT 05292820T PT 1891962 E PT1891962 E PT 1891962E
Authority
PT
Portugal
Prior art keywords
delivery system
based delivery
glutathione based
glutathione
delivery
Prior art date
Application number
PT52928207T
Other languages
English (en)
Inventor
Ae-June Wang
Chi-Heng Jian
Yi-Fong Lin
Shih-Jr Liu
Shyh-Dar Li
Original Assignee
Ind Tech Res Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ind Tech Res Inst filed Critical Ind Tech Res Inst
Publication of PT1891962E publication Critical patent/PT1891962E/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06Tripeptides
    • A61K38/063Glutathione
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6905Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion
    • A61K47/6911Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion the form being a liposome
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02Muscle relaxants, e.g. for tetanus or cramps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00Nanotechnology
    • Y10S977/70Nanostructure
    • Y10S977/773Nanoparticle, i.e. structure having three dimensions of 100 nm or less

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Neurology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Polyethers (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PT52928207T 2005-12-19 2005-12-29 Sistema de administração à base de glutationa PT1891962E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US11/303,934 US7446096B2 (en) 2005-12-19 2005-12-19 Glutathione based delivery system

Publications (1)

Publication Number Publication Date
PT1891962E true PT1891962E (pt) 2014-11-11

Family

ID=36217526

Family Applications (1)

Application Number Title Priority Date Filing Date
PT52928207T PT1891962E (pt) 2005-12-19 2005-12-29 Sistema de administração à base de glutationa

Country Status (11)

Country Link
US (4) US7446096B2 (pt)
EP (2) EP1891962B1 (pt)
JP (2) JP4773200B2 (pt)
CN (2) CN1985804B (pt)
CY (1) CY1115542T1 (pt)
DK (1) DK1891962T3 (pt)
ES (1) ES2516665T3 (pt)
PL (1) PL1891962T3 (pt)
PT (1) PT1891962E (pt)
SI (1) SI1891962T1 (pt)
TW (1) TWI365754B (pt)

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* Cited by examiner, † Cited by third party
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AUPR549901A0 (en) * 2001-06-06 2001-07-12 Vital Health Sciences Pty Ltd Topical formulation containing tocopheryl phosphates
AU2002950713A0 (en) 2002-08-09 2002-09-12 Vital Health Sciences Pty Ltd Carrier
US20040057983A1 (en) 2002-09-25 2004-03-25 David Schmidt Biomolecular wearable apparatus
CA2557354C (en) * 2004-03-03 2013-05-07 Vital Health Sciences Pty Ltd. Alkaloid formulations
CA2575587C (en) * 2004-08-03 2014-06-17 Vital Health Sciences Pty Ltd Carrier for enteral administration
US20090239827A1 (en) * 2005-03-03 2009-09-24 Esra Ogru Compounds having lipid lowering properties
US9168216B2 (en) 2005-06-17 2015-10-27 Vital Health Sciences Pty. Ltd. Carrier comprising one or more di and/or mono-(electron transfer agent) phosphate derivatives or complexes thereof
US8067380B2 (en) * 2005-12-19 2011-11-29 Industrial Technology Research Institute Glutathione-based delivery system
US7446096B2 (en) * 2005-12-19 2008-11-04 Industrial Technology Research Institute Glutathione based delivery system
EP2125024B1 (en) * 2007-03-23 2013-02-13 TO-BBB Holding B.V. Targeted intracellular delivery of antiviral agents
FR2926725B1 (fr) * 2008-01-25 2010-09-03 Biochimie Appliquee Soc Compositions cosmetiques et/ou dermatologiques cicatrisantes
US8602961B2 (en) 2008-05-15 2013-12-10 Lifewave Products Llc Apparatus and method of stimulating elevation of glutathione levels in a subject
WO2010061881A1 (ja) 2008-11-26 2010-06-03 中外製薬株式会社 C型肝炎ウイルスの働きを阻害するオリゴリボヌクレオチドまたはペプチド核酸
KR101727333B1 (ko) * 2008-11-26 2017-04-14 추가이 세이야쿠 가부시키가이샤 베시클 제제
DK2398500T3 (da) * 2009-02-20 2019-05-13 2 Bbb Medicines B V Glutathion-baseret lægemiddelafgivelsessystem
AU2011213557B2 (en) 2010-02-05 2015-05-07 Phosphagenics Limited Carrier comprising non-neutralised tocopheryl phosphate
BR112012024835A2 (pt) * 2010-03-30 2016-06-07 Phosphagenics Ltd adesivo de distribuição transdérmica
WO2012122586A1 (en) 2011-03-15 2012-09-20 Phosphagenics Limited New composition
GB201302427D0 (en) 2013-02-12 2013-03-27 Midatech Ltd Nanoparticle delivery compositions
EP3038657A2 (en) 2013-08-28 2016-07-06 Bioasis Technologies Inc. Cns-targeted conjugates having modified fc regions and methods of use thereof
JP6529012B2 (ja) 2013-10-08 2019-06-12 エイアイ・セラピューティクス・インコーポレーテッド リンパ脈管筋腫症の処置のためのラパマイシン
US10765755B1 (en) * 2013-11-20 2020-09-08 University Of South Florida Preparation and characterization of methylene blue nanoparticles for Alzheimer's disease and other tauopathies
CA2944075C (en) 2014-04-04 2022-06-28 Lam Therapeutics, Inc. An inhalable rapamycin formulation for treating age-related conditions
WO2015154897A1 (en) * 2014-04-08 2015-10-15 Wolfgang Stremmel Means and methods for treating disorders of copper metabolism
WO2015161295A1 (en) * 2014-04-17 2015-10-22 The Corporation Of Mercer University Vitamin e-based nanocarriers for drug delivery and methods of making and using the same
RU2732908C2 (ru) 2014-10-07 2020-09-24 ЭйАй ТЕРАПЬЮТИКС, ИНК. Ингаляционная лекарственная форма рапамицина для лечения легочной гипертензии
US10758520B1 (en) 2015-05-20 2020-09-01 University Of South Florida Glutathione-coated nanoparticles for delivery of MKT-077 across the blood-brain barrier
EP3383371B1 (en) 2015-12-09 2024-05-01 Avecho Biotechnology Limited Pharmaceutical formulation
CA3045702A1 (en) 2016-12-21 2018-06-28 Phosphagenics Limited Phosphorylation process of complex alcohols
US10226442B2 (en) * 2017-07-10 2019-03-12 Syneurx International (Taiwan) Corp. Lithium salts of N-substituted glycine compounds and uses thereof
US10842755B2 (en) 2018-03-23 2020-11-24 University Of South Carolina Nanoparticles for brain targeted drug delivery
US20200048305A1 (en) * 2018-08-10 2020-02-13 South Dakota Board Of Regents Glutathione-cholesterol derivatives as brain targeting agents
KR102465308B1 (ko) * 2019-05-28 2022-11-11 울산과학기술원 글루타치온-s-전이효소 및 표적 세포 또는 표적 단백질 결합능을 갖는 단백질을 포함하는 리포좀 및 이의 용도
CA3128035A1 (en) 2020-08-13 2022-02-13 Bioasis Technologies, Inc. Combination therapies for delivery across the blood brain barrier
TW202228792A (zh) 2020-10-09 2022-08-01 殷漢生技股份有限公司 吸入用奈米載體製劑

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JPS60142915A (ja) 1983-12-28 1985-07-29 Lion Corp 口腔用組成物
JPS632922A (ja) 1986-06-20 1988-01-07 Yamanouchi Pharmaceut Co Ltd ドラツグキヤリア
JPH0714865B2 (ja) * 1986-10-28 1995-02-22 武田薬品工業株式会社 リポソ−ム製剤およびその製造法
FR2627385B3 (fr) 1988-02-23 1991-08-23 Serobiologiques Lab Sa Composition notamment utile comme matiere de base pour la preparation de compositions pharmaceutiques, notamment dermatologiques et/ou cosmetiques
US5695751A (en) 1993-04-08 1997-12-09 Cornell Research Foundation, Inc. Enhancing delivery of large neutral amino acid drugs
JPH0834779A (ja) * 1994-05-20 1996-02-06 Senju Pharmaceut Co Ltd トコフェロール誘導体
US6653331B2 (en) 1996-07-03 2003-11-25 Pharmacia & Upjohn Company Targeted drug delivery using sulfonamide derivatives
WO1998008490A1 (en) * 1996-09-01 1998-03-05 Pharmos Corporation Solid coprecipitates for enhanced bioavailability of lipophilic substances
JP2001503396A (ja) * 1996-10-11 2001-03-13 アルザ コーポレイション 治療用リポソーム組成物および方法
US6228347B1 (en) 1997-12-01 2001-05-08 Thione International, Inc. Antioxidant gel for gingival conditions
CA2328731A1 (en) * 1998-04-16 1999-10-28 Atsushi Imaizumi Glutathione derivatives and dosage forms thereof
JP2004323486A (ja) * 2003-04-30 2004-11-18 National Institute Of Advanced Industrial & Technology 網膜及び/又はブドウ膜疾患の予防乃至治療用点眼薬
CN100515390C (zh) * 2005-04-14 2009-07-22 蔡海德 垂体前叶肾上腺皮质提取物纳米脂质体组合药物及其制备方法和用途
US7446096B2 (en) * 2005-12-19 2008-11-04 Industrial Technology Research Institute Glutathione based delivery system
US8067380B2 (en) * 2005-12-19 2011-11-29 Industrial Technology Research Institute Glutathione-based delivery system

Also Published As

Publication number Publication date
PL1891962T3 (pl) 2015-01-30
US20070141133A1 (en) 2007-06-21
CN1985804A (zh) 2007-06-27
US20100166849A1 (en) 2010-07-01
US20090060991A1 (en) 2009-03-05
EP1891962B1 (en) 2014-08-13
SI1891962T1 (sl) 2014-12-31
JP2007169252A (ja) 2007-07-05
EP1891962A1 (en) 2008-02-27
JP5394944B2 (ja) 2014-01-22
CN1985804B (zh) 2014-05-14
EP2837384A1 (en) 2015-02-18
US7704956B2 (en) 2010-04-27
US7446096B2 (en) 2008-11-04
US20080095836A1 (en) 2008-04-24
CY1115542T1 (el) 2017-01-04
ES2516665T3 (es) 2014-10-31
US8569239B2 (en) 2013-10-29
JP4773200B2 (ja) 2011-09-14
CN101385859B (zh) 2011-12-07
JP2010150264A (ja) 2010-07-08
DK1891962T3 (da) 2014-10-13
CN101385859A (zh) 2009-03-18
TWI365754B (en) 2012-06-11
US7700564B2 (en) 2010-04-20

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