TWI325890B - - Google Patents
Download PDFInfo
- Publication number
- TWI325890B TWI325890B TW96105782A TW96105782A TWI325890B TW I325890 B TWI325890 B TW I325890B TW 96105782 A TW96105782 A TW 96105782A TW 96105782 A TW96105782 A TW 96105782A TW I325890 B TWI325890 B TW I325890B
- Authority
- TW
- Taiwan
- Prior art keywords
- cordyceps
- culture
- report
- cordycepic
- cordyceps militaris
- Prior art date
Links
- 241001264174 Cordyceps militaris Species 0.000 claims description 37
- 235000007164 Oryza sativa Nutrition 0.000 claims description 29
- 240000000111 Saccharum officinarum Species 0.000 claims description 29
- 235000007201 Saccharum officinarum Nutrition 0.000 claims description 29
- 235000009566 rice Nutrition 0.000 claims description 29
- 239000000835 fiber Substances 0.000 claims description 24
- 241000190633 Cordyceps Species 0.000 claims description 22
- 238000009941 weaving Methods 0.000 claims description 9
- 239000007787 solid Substances 0.000 claims description 5
- 241000894007 species Species 0.000 claims description 4
- 238000011049 filling Methods 0.000 claims description 2
- 241000209094 Oryza Species 0.000 claims 4
- 240000007594 Oryza sativa Species 0.000 description 25
- 241001248610 Ophiocordyceps sinensis Species 0.000 description 24
- 238000004458 analytical method Methods 0.000 description 12
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 description 10
- 239000000047 product Substances 0.000 description 10
- 239000002609 medium Substances 0.000 description 9
- 102000019197 Superoxide Dismutase Human genes 0.000 description 8
- 108010012715 Superoxide dismutase Proteins 0.000 description 8
- KQLDDLUWUFBQHP-UHFFFAOYSA-N Cordycepin Natural products C1=NC=2C(N)=NC=NC=2N1C1OCC(CO)C1O KQLDDLUWUFBQHP-UHFFFAOYSA-N 0.000 description 7
- OFEZSBMBBKLLBJ-BAJZRUMYSA-N cordycepin Chemical compound C1=NC=2C(N)=NC=NC=2N1[C@@H]1O[C@H](CO)C[C@H]1O OFEZSBMBBKLLBJ-BAJZRUMYSA-N 0.000 description 7
- OFEZSBMBBKLLBJ-UHFFFAOYSA-N cordycepine Natural products C1=NC=2C(N)=NC=NC=2N1C1OC(CO)CC1O OFEZSBMBBKLLBJ-UHFFFAOYSA-N 0.000 description 7
- 230000000694 effects Effects 0.000 description 7
- 238000012360 testing method Methods 0.000 description 7
- 238000012136 culture method Methods 0.000 description 6
- 150000004676 glycans Chemical class 0.000 description 6
- 238000007689 inspection Methods 0.000 description 6
- 229920001282 polysaccharide Polymers 0.000 description 6
- 239000005017 polysaccharide Substances 0.000 description 6
- 241000894006 Bacteria Species 0.000 description 5
- 241000233866 Fungi Species 0.000 description 5
- 230000000844 anti-bacterial effect Effects 0.000 description 5
- 239000008280 blood Substances 0.000 description 5
- 210000004369 blood Anatomy 0.000 description 5
- 235000013399 edible fruits Nutrition 0.000 description 5
- 241001018099 Alloteropsis Species 0.000 description 4
- 235000017898 Digitaria ciliaris Nutrition 0.000 description 4
- 241000238631 Hexapoda Species 0.000 description 4
- 235000013305 food Nutrition 0.000 description 4
- 239000007788 liquid Substances 0.000 description 4
- 210000004072 lung Anatomy 0.000 description 4
- 239000000203 mixture Substances 0.000 description 4
- 230000000144 pharmacologic effect Effects 0.000 description 4
- 150000003254 radicals Chemical class 0.000 description 4
- 241000193830 Bacillus <bacterium> Species 0.000 description 3
- MUBZPKHOEPUJKR-UHFFFAOYSA-N Oxalic acid Chemical compound OC(=O)C(O)=O MUBZPKHOEPUJKR-UHFFFAOYSA-N 0.000 description 3
- 239000004480 active ingredient Substances 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 3
- 239000001963 growth medium Substances 0.000 description 3
- 210000003734 kidney Anatomy 0.000 description 3
- 235000015097 nutrients Nutrition 0.000 description 3
- 238000011160 research Methods 0.000 description 3
- 229920001817 Agar Polymers 0.000 description 2
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
- 244000025254 Cannabis sativa Species 0.000 description 2
- 206010011224 Cough Diseases 0.000 description 2
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 2
- 206010062717 Increased upper airway secretion Diseases 0.000 description 2
- 240000004808 Saccharomyces cerevisiae Species 0.000 description 2
- 244000269722 Thea sinensis Species 0.000 description 2
- OIRDTQYFTABQOQ-KQYNXXCUSA-N adenosine Chemical compound C1=NC=2C(N)=NC=NC=2N1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O OIRDTQYFTABQOQ-KQYNXXCUSA-N 0.000 description 2
- 239000008272 agar Substances 0.000 description 2
- 235000001014 amino acid Nutrition 0.000 description 2
- 150000001413 amino acids Chemical class 0.000 description 2
- 230000003712 anti-aging effect Effects 0.000 description 2
- 230000001093 anti-cancer Effects 0.000 description 2
- 230000000259 anti-tumor effect Effects 0.000 description 2
- 230000000840 anti-viral effect Effects 0.000 description 2
- 230000000740 bleeding effect Effects 0.000 description 2
- 229910052799 carbon Inorganic materials 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 238000003306 harvesting Methods 0.000 description 2
- 230000000147 hypnotic effect Effects 0.000 description 2
- 230000036039 immunity Effects 0.000 description 2
- 239000002398 materia medica Substances 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 208000026435 phlegm Diseases 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 230000001624 sedative effect Effects 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 238000011282 treatment Methods 0.000 description 2
- 239000012137 tryptone Substances 0.000 description 2
- 201000008827 tuberculosis Diseases 0.000 description 2
- 210000001835 viscera Anatomy 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- OILXMJHPFNGGTO-UHFFFAOYSA-N (22E)-(24xi)-24-methylcholesta-5,22-dien-3beta-ol Natural products C1C=C2CC(O)CCC2(C)C2C1C1CCC(C(C)C=CC(C)C(C)C)C1(C)CC2 OILXMJHPFNGGTO-UHFFFAOYSA-N 0.000 description 1
- RQOCXCFLRBRBCS-UHFFFAOYSA-N (22E)-cholesta-5,7,22-trien-3beta-ol Natural products C1C(O)CCC2(C)C(CCC3(C(C(C)C=CCC(C)C)CCC33)C)C3=CC=C21 RQOCXCFLRBRBCS-UHFFFAOYSA-N 0.000 description 1
- XDIYNQZUNSSENW-UUBOPVPUSA-N (2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanal Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C=O XDIYNQZUNSSENW-UUBOPVPUSA-N 0.000 description 1
- MQWCQFCZUNBTCM-UHFFFAOYSA-N 2-tert-butyl-6-(3-tert-butyl-2-hydroxy-5-methylphenyl)sulfanyl-4-methylphenol Chemical compound CC(C)(C)C1=CC(C)=CC(SC=2C(=C(C=C(C)C=2)C(C)(C)C)O)=C1O MQWCQFCZUNBTCM-UHFFFAOYSA-N 0.000 description 1
- OQMZNAMGEHIHNN-UHFFFAOYSA-N 7-Dehydrostigmasterol Natural products C1C(O)CCC2(C)C(CCC3(C(C(C)C=CC(CC)C(C)C)CCC33)C)C3=CC=C21 OQMZNAMGEHIHNN-UHFFFAOYSA-N 0.000 description 1
- 241001600407 Aphis <genus> Species 0.000 description 1
- 208000006820 Arthralgia Diseases 0.000 description 1
- 241001480043 Arthrodermataceae Species 0.000 description 1
- 241000235349 Ascomycota Species 0.000 description 1
- 241000193738 Bacillus anthracis Species 0.000 description 1
- 208000035143 Bacterial infection Diseases 0.000 description 1
- 108091085748 Bat family Proteins 0.000 description 1
- OMPJBNCRMGITSC-UHFFFAOYSA-N Benzoylperoxide Chemical compound C=1C=CC=CC=1C(=O)OOC(=O)C1=CC=CC=C1 OMPJBNCRMGITSC-UHFFFAOYSA-N 0.000 description 1
- 241001674044 Blattodea Species 0.000 description 1
- 239000002126 C01EB10 - Adenosine Substances 0.000 description 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
- DNVPQKQSNYMLRS-NXVQYWJNSA-N Ergosterol Natural products CC(C)[C@@H](C)C=C[C@H](C)[C@H]1CC[C@H]2C3=CC=C4C[C@@H](O)CC[C@]4(C)[C@@H]3CC[C@]12C DNVPQKQSNYMLRS-NXVQYWJNSA-N 0.000 description 1
- 235000019733 Fish meal Nutrition 0.000 description 1
- 206010018367 Glomerulonephritis chronic Diseases 0.000 description 1
- 241000330899 Hepialus Species 0.000 description 1
- 206010021143 Hypoxia Diseases 0.000 description 1
- ONIBWKKTOPOVIA-BYPYZUCNSA-N L-Proline Chemical compound OC(=O)[C@@H]1CCCN1 ONIBWKKTOPOVIA-BYPYZUCNSA-N 0.000 description 1
- CKLJMWTZIZZHCS-REOHCLBHSA-N L-aspartic acid Chemical compound OC(=O)[C@@H](N)CC(O)=O CKLJMWTZIZZHCS-REOHCLBHSA-N 0.000 description 1
- 241000222722 Leishmania <genus> Species 0.000 description 1
- 229930195725 Mannitol Natural products 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 241000699670 Mus sp. Species 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 206010067482 No adverse event Diseases 0.000 description 1
- 241000256259 Noctuidae Species 0.000 description 1
- 206010059013 Nocturnal emission Diseases 0.000 description 1
- 208000002193 Pain Diseases 0.000 description 1
- 239000001888 Peptone Substances 0.000 description 1
- 108010080698 Peptones Proteins 0.000 description 1
- 206010036790 Productive cough Diseases 0.000 description 1
- ONIBWKKTOPOVIA-UHFFFAOYSA-N Proline Natural products OC(=O)C1CCCN1 ONIBWKKTOPOVIA-UHFFFAOYSA-N 0.000 description 1
- 206010039509 Scab Diseases 0.000 description 1
- 241001558929 Sclerotium <basidiomycota> Species 0.000 description 1
- 241000239226 Scorpiones Species 0.000 description 1
- 206010039897 Sedation Diseases 0.000 description 1
- 241000191940 Staphylococcus Species 0.000 description 1
- 229920002472 Starch Polymers 0.000 description 1
- 241000194017 Streptococcus Species 0.000 description 1
- 230000005856 abnormality Effects 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 229960005305 adenosine Drugs 0.000 description 1
- 230000032683 aging Effects 0.000 description 1
- 238000010171 animal model Methods 0.000 description 1
- 230000002929 anti-fatigue Effects 0.000 description 1
- 230000003064 anti-oxidating effect Effects 0.000 description 1
- 230000002155 anti-virotic effect Effects 0.000 description 1
- 230000000890 antigenic effect Effects 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 230000003078 antioxidant effect Effects 0.000 description 1
- 235000003704 aspartic acid Nutrition 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 230000003385 bacteriostatic effect Effects 0.000 description 1
- OQFSQFPPLPISGP-UHFFFAOYSA-N beta-carboxyaspartic acid Natural products OC(=O)C(N)C(C(O)=O)C(O)=O OQFSQFPPLPISGP-UHFFFAOYSA-N 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 238000009534 blood test Methods 0.000 description 1
- 230000037396 body weight Effects 0.000 description 1
- 238000009835 boiling Methods 0.000 description 1
- 210000000621 bronchi Anatomy 0.000 description 1
- 229940041514 candida albicans extract Drugs 0.000 description 1
- 239000001913 cellulose Substances 0.000 description 1
- 229920002678 cellulose Polymers 0.000 description 1
- 208000013116 chronic cough Diseases 0.000 description 1
- 230000000052 comparative effect Effects 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 229940098364 cordyceps sinensis preparation Drugs 0.000 description 1
- 238000012364 cultivation method Methods 0.000 description 1
- 230000037304 dermatophytes Effects 0.000 description 1
- 239000008121 dextrose Substances 0.000 description 1
- 238000000921 elemental analysis Methods 0.000 description 1
- DNVPQKQSNYMLRS-SOWFXMKYSA-N ergosterol Chemical compound C1[C@@H](O)CC[C@]2(C)[C@H](CC[C@]3([C@H]([C@H](C)/C=C/[C@@H](C)C(C)C)CC[C@H]33)C)C3=CC=C21 DNVPQKQSNYMLRS-SOWFXMKYSA-N 0.000 description 1
- 239000000284 extract Substances 0.000 description 1
- 238000000855 fermentation Methods 0.000 description 1
- 230000004151 fermentation Effects 0.000 description 1
- 239000004467 fishmeal Substances 0.000 description 1
- 238000004186 food analysis Methods 0.000 description 1
- 235000021022 fresh fruits Nutrition 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 229910001385 heavy metal Inorganic materials 0.000 description 1
- 238000007602 hot air drying Methods 0.000 description 1
- 239000000413 hydrolysate Substances 0.000 description 1
- 230000036737 immune function Effects 0.000 description 1
- 230000003832 immune regulation Effects 0.000 description 1
- 201000001881 impotence Diseases 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 238000011081 inoculation Methods 0.000 description 1
- 230000003907 kidney function Effects 0.000 description 1
- 208000024765 knee pain Diseases 0.000 description 1
- 208000037805 labour Diseases 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
- 238000009630 liquid culture Methods 0.000 description 1
- 230000003908 liver function Effects 0.000 description 1
- 239000000594 mannitol Substances 0.000 description 1
- 235000010355 mannitol Nutrition 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000000691 measurement method Methods 0.000 description 1
- 230000007721 medicinal effect Effects 0.000 description 1
- 238000002844 melting Methods 0.000 description 1
- 230000008018 melting Effects 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 235000006408 oxalic acid Nutrition 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 230000003071 parasitic effect Effects 0.000 description 1
- 235000019319 peptone Nutrition 0.000 description 1
- 230000037081 physical activity Effects 0.000 description 1
- 230000003405 preventing effect Effects 0.000 description 1
- 235000018102 proteins Nutrition 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 238000004451 qualitative analysis Methods 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 238000004626 scanning electron microscopy Methods 0.000 description 1
- 230000002000 scavenging effect Effects 0.000 description 1
- 230000036280 sedation Effects 0.000 description 1
- 239000000932 sedative agent Substances 0.000 description 1
- 230000001568 sexual effect Effects 0.000 description 1
- 239000002893 slag Substances 0.000 description 1
- 239000002689 soil Substances 0.000 description 1
- 208000024794 sputum Diseases 0.000 description 1
- 210000003802 sputum Anatomy 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 238000010025 steaming Methods 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 235000013619 trace mineral Nutrition 0.000 description 1
- 239000011573 trace mineral Substances 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 239000012138 yeast extract Substances 0.000 description 1
Landscapes
- Mushroom Cultivation (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Plant Substances (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| TW96105782A TW200833836A (en) | 2007-02-15 | 2007-02-15 | An improved method of cultivating the Cordyceps Militaris by adding sugar cane fiber |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| TW96105782A TW200833836A (en) | 2007-02-15 | 2007-02-15 | An improved method of cultivating the Cordyceps Militaris by adding sugar cane fiber |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TW200833836A TW200833836A (en) | 2008-08-16 |
| TWI325890B true TWI325890B (https=) | 2010-06-11 |
Family
ID=44819243
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW96105782A TW200833836A (en) | 2007-02-15 | 2007-02-15 | An improved method of cultivating the Cordyceps Militaris by adding sugar cane fiber |
Country Status (1)
| Country | Link |
|---|---|
| TW (1) | TW200833836A (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102405763B (zh) * | 2010-09-26 | 2013-06-19 | 王美才 | 一种冬虫夏草的培育方法 |
| CN102835245B (zh) * | 2011-06-24 | 2014-03-26 | 浙江泛亚生物医药股份有限公司 | 一种蝉花的仿生培养方法 |
| CN103733875B (zh) * | 2013-11-08 | 2016-11-16 | 吉林省农业科学院 | 北虫草工厂化生产方法及工艺 |
| CN109479613A (zh) * | 2018-11-12 | 2019-03-19 | 广州玖玖伍捌健康科技股份有限公司 | 一种用离子维c桑叶培养虫草菌丝的组合物及其培养方法 |
| CN113980820A (zh) * | 2021-11-04 | 2022-01-28 | 锬酃藏虫草生物科技(深圳)有限公司 | 一种蛹虫草中虫草素和腺苷含量的培养方法 |
-
2007
- 2007-02-15 TW TW96105782A patent/TW200833836A/zh not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| TW200833836A (en) | 2008-08-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN104145719B (zh) | 一种冬虫夏草菌菌丝体发酵生产方法 | |
| CN103315362B (zh) | 一种茯苓固态发酵功能饮品及制备方法 | |
| CN104920065B (zh) | 一种梵净山野生红托竹荪母种制作方法 | |
| CN102835245B (zh) | 一种蝉花的仿生培养方法 | |
| CN104285669B (zh) | 一株桑黄菌株及其应用 | |
| CN116162551B (zh) | 一种滇中灵芝菌株l4741与应用 | |
| JP2023099425A (ja) | オニノヤガラの有機栽培方法 | |
| CN101991043A (zh) | 液体发酵松茸菌丝体多糖复合燕麦营养餐加工方法 | |
| TWI325890B (https=) | ||
| CN103215311A (zh) | 一种利用黑曲霉菌转化生产优质沉香的方法 | |
| US20250333805A1 (en) | Hericium erinaceus strain he015, molecular markers and uses thereof | |
| CN107027516A (zh) | 一种富硒蝉花虫草、其培养方法及应用 | |
| CN104254594A (zh) | 添加硒原液可排出放射性锶的功能性马格利酒及其制造方法 | |
| KR101799400B1 (ko) | 아미노산을 포함하는 꽃송이버섯 균사체의 배양배지 조성물 및 이를 이용한 감마-아미노부티르산이 증진된 꽃송이버섯 균사체 생산 방법 | |
| CN114989986A (zh) | 一种富含多种活性成分的野生桑黄菌及其培养方法、应用 | |
| CN118879514A (zh) | 一种黑木耳菌株l7013及其栽培方法 | |
| CN103555618A (zh) | 一株解淀粉芽孢杆菌及其液体制剂在治疗松烂皮病中的应用 | |
| CN102613186A (zh) | 壳聚糖在防治植物细菌性果斑病中的应用 | |
| KR20140089242A (ko) | 박쥐나방 동충하초 균사체의 배양방법 및 그 배양방법으로 배양된 박쥐나방동충하초 균사체 | |
| CN118020827A (zh) | 一种挥发油复合物及其在桃贮藏中的应用 | |
| CN107828664B (zh) | 裂褶菌xt-1及其栽培方法与应用 | |
| CN104322272A (zh) | 一种以蚯蚓为载体培养人工蛹虫草的方法 | |
| CN117044561A (zh) | 一种替代松木的茯苓种植方法以及茯苓接种基质 | |
| CN117337847A (zh) | 纳豆芽孢杆菌和米曲霉复合发酵豆粕产物在减轻苹果连作障碍上的应用 | |
| CN109652479A (zh) | 一种提高石斛多糖抗氧化能力的方法 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | Annulment or lapse of patent due to non-payment of fees |