TWI316405B - A pharmaceutical composition for reducing pain in a mammal suffering from a neoplasm - Google Patents

A pharmaceutical composition for reducing pain in a mammal suffering from a neoplasm Download PDF

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Publication number
TWI316405B
TWI316405B TW092112420A TW92112420A TWI316405B TW I316405 B TWI316405 B TW I316405B TW 092112420 A TW092112420 A TW 092112420A TW 92112420 A TW92112420 A TW 92112420A TW I316405 B TWI316405 B TW I316405B
Authority
TW
Taiwan
Prior art keywords
reovirus
virus
pharmaceutical composition
pain
tumor
Prior art date
Application number
TW092112420A
Other languages
English (en)
Chinese (zh)
Other versions
TW200402305A (en
Inventor
Donald Morris
Matthew C Coffey
Bradley G Thompson
Original Assignee
Oncolytics Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oncolytics Biotech Inc filed Critical Oncolytics Biotech Inc
Publication of TW200402305A publication Critical patent/TW200402305A/zh
Application granted granted Critical
Publication of TWI316405B publication Critical patent/TWI316405B/zh

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/76—Viruses; Subviral particles; Bacteriophages
    • A61K35/765—Reovirus; Rotavirus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011—Details
    • C12N2720/12011—Reoviridae
    • C12N2720/12211—Orthoreovirus, e.g. mammalian orthoreovirus
    • C12N2720/12232—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
TW092112420A 2002-05-09 2003-05-07 A pharmaceutical composition for reducing pain in a mammal suffering from a neoplasm TWI316405B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US37867502P 2002-05-09 2002-05-09
US44317703P 2003-01-29 2003-01-29

Publications (2)

Publication Number Publication Date
TW200402305A TW200402305A (en) 2004-02-16
TWI316405B true TWI316405B (en) 2009-11-01

Family

ID=29423642

Family Applications (1)

Application Number Title Priority Date Filing Date
TW092112420A TWI316405B (en) 2002-05-09 2003-05-07 A pharmaceutical composition for reducing pain in a mammal suffering from a neoplasm

Country Status (19)

Country Link
US (2) US20040091458A1 (https=)
EP (1) EP1505992B1 (https=)
JP (1) JP5241059B2 (https=)
AR (1) AR039986A1 (https=)
AT (1) ATE404213T1 (https=)
AU (1) AU2003229431B8 (https=)
BR (1) BR0309825A (https=)
CA (1) CA2484398C (https=)
DE (2) DE03722131T1 (https=)
DK (1) DK1505992T3 (https=)
ES (1) ES2239928T3 (https=)
IL (1) IL164695A (https=)
MX (1) MXPA04011007A (https=)
NZ (1) NZ536102A (https=)
PT (1) PT1505992E (https=)
SI (1) SI1505992T1 (https=)
TR (1) TR200501460T3 (https=)
TW (1) TWI316405B (https=)
WO (1) WO2003094938A1 (https=)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPQ425699A0 (en) 1999-11-25 1999-12-23 University Of Newcastle Research Associates Limited, The A method of treating a malignancy in a subject and a pharmaceutical composition for use in same
AU2002953436A0 (en) 2002-12-18 2003-01-09 The University Of Newcastle Research Associates Limited A method of treating a malignancy in a subject via direct picornaviral-mediated oncolysis
US10260049B2 (en) 2005-08-01 2019-04-16 Virocure, Inc. Attenuated reovirus
US10668119B2 (en) 2005-08-01 2020-06-02 Virocure, Inc. Attenuated reovirus
US10369171B2 (en) 2007-03-13 2019-08-06 Virocure, Inc. Attenuated reoviruses for selection of cell populations
WO2008144067A1 (en) * 2007-05-21 2008-11-27 Board Of Regents, University Of Texas System Methods and compositions for treatment of cancer using oncolytic rsv activity
US8450106B2 (en) * 2007-10-17 2013-05-28 The Ohio State University Research Foundation Oncolytic virus
EP2296678A4 (en) * 2008-05-27 2012-03-21 Oncolytics Biotech Inc MODULATION OF INTERSTITIAL PRESSURE AND ONCOLYTIC VIRUS RELIEF AND DISTRIBUTION
KR20100054358A (ko) * 2008-11-14 2010-05-25 김재은 스틱 연고
RU2554740C2 (ru) * 2009-05-01 2015-06-27 Апталис Фарматек, Инк. Композиции перорально распадающихся таблеток, содержащие комбинации высоко- и низкодозовых лекарственных средств
EP2383577A1 (en) * 2010-04-30 2011-11-02 Deutsches Krebsforschungszentrum Diagnostic method for predicting the response of a patient to chemovirotherapy or radiovirotherapy
JP6827467B2 (ja) 2015-06-19 2021-02-10 シルラジェン，インコーポレイテッド ウイルス塞栓術のための組成物および方法
EP3417866B1 (en) 2016-02-16 2020-12-23 Osaka University Medicinal composition for treating fibrosis

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5023252A (en) * 1985-12-04 1991-06-11 Conrex Pharmaceutical Corporation Transdermal and trans-membrane delivery of drugs
US6110461A (en) * 1997-08-13 2000-08-29 Oncolytics Biotech Inc. Reovirus for the treatment of neoplasia
US6136307A (en) * 1997-08-13 2000-10-24 Oncolytics Biotech Inc. Reovirus for the treatment of cellular proliferative disorders
CN101618049A (zh) * 1997-10-09 2010-01-06 威尔斯塔特生物公司 使用病毒来治疗赘生物
US6428968B1 (en) * 1999-03-15 2002-08-06 The Trustees Of The University Of Pennsylvania Combined therapy with a chemotherapeutic agent and an oncolytic virus for killing tumor cells in a subject
TWI289158B (en) * 2000-08-10 2007-11-01 Oncolytics Biotech Inc Method of producing infectious reovirus

Also Published As

Publication number Publication date
IL164695A0 (en) 2005-12-18
WO2003094938A1 (en) 2003-11-20
CA2484398A1 (en) 2003-11-20
ES2239928T1 (es) 2005-10-16
JP5241059B2 (ja) 2013-07-17
AU2003229431A1 (en) 2003-11-11
US20040091458A1 (en) 2004-05-13
JP2005526124A (ja) 2005-09-02
US20080081032A1 (en) 2008-04-03
PT1505992E (pt) 2008-10-06
NZ536102A (en) 2008-01-31
TW200402305A (en) 2004-02-16
DE03722131T1 (de) 2005-09-15
HK1070565A1 (en) 2005-06-24
AR039986A1 (es) 2005-03-09
EP1505992B1 (en) 2008-08-13
SI1505992T1 (sl) 2009-02-28
ES2239928T3 (es) 2009-02-16
ATE404213T1 (de) 2008-08-15
BR0309825A (pt) 2005-03-01
MXPA04011007A (es) 2005-02-14
TR200501460T3 (tr) 2005-06-21
IL164695A (en) 2010-12-30
DK1505992T3 (da) 2008-10-06
DE60322885D1 (de) 2008-09-25
AU2003229431B2 (en) 2008-01-17
EP1505992A1 (en) 2005-02-16
CA2484398C (en) 2014-01-21
AU2003229431B8 (en) 2009-07-02

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