TWI306406B - Regenerative bone implants - Google Patents

Regenerative bone implants Download PDF

Info

Publication number
TWI306406B
TWI306406B TW091120185A TW91120185A TWI306406B TW I306406 B TWI306406 B TW I306406B TW 091120185 A TW091120185 A TW 091120185A TW 91120185 A TW91120185 A TW 91120185A TW I306406 B TWI306406 B TW I306406B
Authority
TW
Taiwan
Prior art keywords
bone
matrix
biocompatible
biodegradable
bone regenerative
Prior art date
Application number
TW091120185A
Other languages
English (en)
Chinese (zh)
Inventor
Thomas Lai Wen-Fu
Wen Ping Deng
Yu Hmi Tsai
Wing P Chan
Wei Chung Yang
Pham Wellington
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Application granted granted Critical
Publication of TWI306406B publication Critical patent/TWI306406B/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L89/00—Compositions of proteins; Compositions of derivatives thereof
    • C08L89/04—Products derived from waste materials, e.g. horn, hoof or hair
    • C08L89/06—Products derived from waste materials, e.g. horn, hoof or hair derived from leather or skin, e.g. gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/227—Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/42—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having an inorganic matrix
    • A61L27/425—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having an inorganic matrix of phosphorus containing material, e.g. apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56—Porous materials, e.g. foams or sponges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/28—Bones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30003—Material related properties of the prosthesis or of a coating on the prosthesis
    • A61F2002/3006—Properties of materials and coating materials
    • A61F2002/30062—(bio)absorbable, biodegradable, bioerodable, (bio)resorbable, resorptive
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2210/0004—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof bioabsorbable
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005—The prosthesis being constructed from a particular material
    • A61F2310/00179—Ceramics or ceramic-like structures
    • A61F2310/00293—Ceramics or ceramic-like structures containing a phosphorus-containing compound, e.g. apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005—The prosthesis being constructed from a particular material
    • A61F2310/00365—Proteins; Polypeptides; Degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Dermatology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Composite Materials (AREA)
  • Materials Engineering (AREA)
  • Materials For Medical Uses (AREA)
TW091120185A 2001-09-05 2002-09-04 Regenerative bone implants TWI306406B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/946,914 US20030045942A1 (en) 2001-09-05 2001-09-05 Regenerative bone implants

Publications (1)

Publication Number Publication Date
TWI306406B true TWI306406B (en) 2009-02-21

Family

ID=25485174

Family Applications (1)

Application Number Title Priority Date Filing Date
TW091120185A TWI306406B (en) 2001-09-05 2002-09-04 Regenerative bone implants

Country Status (4)

Country Link
US (1) US20030045942A1 (OSRAM)
JP (1) JP4796261B2 (OSRAM)
CN (1) CN1268307C (OSRAM)
TW (1) TWI306406B (OSRAM)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8758438B2 (en) * 2000-12-08 2014-06-24 Warsaw Orthopedic, Inc. Implant for orthopedic applications
EP1528938A2 (en) * 2002-08-12 2005-05-11 Osteotech, Inc. Synthesis of a bone-polymer composite material
EP1549359A2 (en) * 2002-10-08 2005-07-06 Osteotech, Inc. Coupling agents for orthopedic biomaterials
US9107751B2 (en) * 2002-12-12 2015-08-18 Warsaw Orthopedic, Inc. Injectable and moldable bone substitute materials
US20050251267A1 (en) * 2004-05-04 2005-11-10 John Winterbottom Cell permeable structural implant
KR20050088380A (ko) * 2002-12-12 2005-09-05 오스테오테크, 인코포레이티드 성형 가능하며 고정 가능한 폴리머 뼈 복합재료 및 그 제조방법
EP1701672A4 (en) * 2003-12-19 2011-04-27 Osteotech Inc TISSUE-BASED MESH FOR BONE REGENERATION
US8012210B2 (en) * 2004-01-16 2011-09-06 Warsaw Orthopedic, Inc. Implant frames for use with settable materials and related methods of use
WO2005074850A1 (en) * 2004-01-30 2005-08-18 Osteotech, Inc. Stacking implants for spinal fusion
US20060045902A1 (en) * 2004-09-01 2006-03-02 Serbousek Jon C Polymeric wrap for in vivo delivery of osteoinductive formulations
US8323348B2 (en) * 2005-02-22 2012-12-04 Taiyen Biotech Co., Ltd. Bone implants
WO2007084609A2 (en) * 2006-01-19 2007-07-26 Osteotech, Inc. Porous osteoimplant
US8673019B2 (en) * 2006-04-13 2014-03-18 Warsaw Orthopedic, Inc. Use of anti-inflammatory compounds with allograft tissue implantation
WO2010138627A2 (en) * 2009-05-29 2010-12-02 The Regents Of The University Of California A method of enhancing bioactivity of implant materials
TWI671420B (zh) * 2018-07-27 2019-09-11 光弘生醫科技股份有限公司 植體電漿鍍膜與分子交聯流程及結構

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996024392A1 (en) * 1995-02-07 1996-08-15 Fidia Advanced Biopolymers, S.R.L. Process for the coating of objects with hyaluronic acid, derivatives thereof, and semisynthetic polymers
US6613544B1 (en) * 1995-12-22 2003-09-02 Amgen Inc. Osteoprotegerin
JP2001527451A (ja) * 1997-05-16 2001-12-25 ノバルティス アクチエンゲゼルシャフト 細胞結合活性を有するコラーゲン様ポリマー
JPH1158067A (ja) * 1997-08-13 1999-03-02 Furukawa Electric Co Ltd:The ろう付け用ペースト及びろう付け用アルミニウム材
US6296667B1 (en) * 1997-10-01 2001-10-02 Phillips-Origen Ceramic Technology, Llc Bone substitutes
DE19803673A1 (de) * 1998-01-30 1999-08-05 Norbert M Dr Meenen Biohybrider Gelenkflächenersatz
JP3729700B2 (ja) * 2000-02-29 2005-12-21 株式会社ノリタケカンパニーリミテド ドレッシング工具の製造方法
JP4809963B2 (ja) * 1999-11-11 2011-11-09 オリンパス株式会社 骨補填材
US20020132753A1 (en) * 2000-01-31 2002-09-19 Rosen Craig A. Nucleic acids, proteins, and antibodies

Also Published As

Publication number Publication date
US20030045942A1 (en) 2003-03-06
CN1268307C (zh) 2006-08-09
JP2003175098A (ja) 2003-06-24
JP4796261B2 (ja) 2011-10-19
CN1440731A (zh) 2003-09-10
HK1059206A1 (en) 2004-06-25

Similar Documents

Publication Publication Date Title
JP5399264B2 (ja) 骨成長粒子及びそれの骨誘導組成物
US8101676B2 (en) Osteogenic paste compositions and uses thereof
US6478825B1 (en) Implant, method of making same and use of the implant for the treatment of bone defects
JP4796261B2 (ja) 再生骨インプラント
JPS60253455A (ja) 骨形成因子を含有する生体材料とその製造方法
JPH0522547B2 (OSRAM)
JPH09505305A (ja) 骨形成促進生成物および骨形成方法
HUP0102991A2 (hu) Osteoimplantum és az előállítására szolgáló módszer
JP2002532159A (ja) 骨移植片及び誘導型骨再生法
KR100871396B1 (ko) 생체활성 아파타이트의 제조방법
KR101348336B1 (ko) 이종골 유래 골이식재 및 그 제조방법
KR101348335B1 (ko) 이종골 유래 골이식재 및 그 제조방법
US20050107286A1 (en) Composite biomaterial comprising phospholine
KR101885896B1 (ko) 인체뼈 유래 무기질을 포함하는 천연 골재생재
JP2005531339A (ja) 組織工学的な整形外科用スキャッフォールド
JPS6040298B2 (ja) 骨欠損部及び空隙部充てん材
CN111526896B (zh) 制备骨引导性聚合物制品的方法和由此制备的骨引导性聚合物制品
US8586099B2 (en) Method for preparing a prion-free bond grafting substitute
JPH07275343A (ja) 自然骨置換型人工骨とその製造方法
HK1059206B (en) Regenerative bone implants
RU2393819C1 (ru) Способ приготовления заменителя костного трансплантата, не содержащего прионов
KR100487693B1 (ko) 골아세포의 부착을 촉진하는 자연골 대체용 인공골 구조재료

Legal Events

Date Code Title Description
MM4A Annulment or lapse of patent due to non-payment of fees