TW546382B - Method of detecting genetic polymorphism using PCR and restriction enzymes - Google Patents

Method of detecting genetic polymorphism using PCR and restriction enzymes Download PDF

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Publication number
TW546382B
TW546382B TW085104439A TW85104439A TW546382B TW 546382 B TW546382 B TW 546382B TW 085104439 A TW085104439 A TW 085104439A TW 85104439 A TW85104439 A TW 85104439A TW 546382 B TW546382 B TW 546382B
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TW
Taiwan
Prior art keywords
nucleic acid
pcr
endonuclease
amplification
polymorphism
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Application number
TW085104439A
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English (en)
Chinese (zh)
Inventor
Alison Velyian Todd
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Johnson & Johnson Res Pty Ltd
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Publication of TW546382B publication Critical patent/TW546382B/zh

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6858—Allele-specific amplification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/16—Primer sets for multiplex assays

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
TW085104439A 1995-04-13 1996-04-13 Method of detecting genetic polymorphism using PCR and restriction enzymes TW546382B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AUPN2452A AUPN245295A0 (en) 1995-04-13 1995-04-13 Assay for genetic abnormalities

Publications (1)

Publication Number Publication Date
TW546382B true TW546382B (en) 2003-08-11

Family

ID=3786805

Family Applications (1)

Application Number Title Priority Date Filing Date
TW085104439A TW546382B (en) 1995-04-13 1996-04-13 Method of detecting genetic polymorphism using PCR and restriction enzymes

Country Status (17)

Country Link
US (1) US6261768B1 (xx)
EP (1) EP0871767B1 (xx)
JP (1) JPH11503027A (xx)
KR (1) KR19980703858A (xx)
CN (1) CN1185181A (xx)
AR (1) AR001619A1 (xx)
AT (1) ATE214429T1 (xx)
AU (1) AUPN245295A0 (xx)
BR (1) BR9604814A (xx)
CA (1) CA2218026A1 (xx)
DE (1) DE69619864T2 (xx)
DK (1) DK0871767T3 (xx)
ES (1) ES2174063T3 (xx)
IL (1) IL117884A0 (xx)
TW (1) TW546382B (xx)
WO (1) WO1996032500A1 (xx)
ZA (1) ZA962941B (xx)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR9908567A (pt) * 1998-03-05 2000-12-12 Johnson & Johnson Res Pty Ltd Processos de detecção de ácido nucléico zimogênico e moléculas relacionadas e kits
EP0953635B1 (en) 1998-04-28 2012-08-29 Ortho-Clinical Diagnostics, Inc. Improved methods for extracting nucleic acids from tissue samples and paraffin-embedded tissues
US6469159B1 (en) 1999-04-26 2002-10-22 Robert T. Belly Methods for extracting nucleic acids from tissue samples and paraffin-embedded tissues
WO2000066783A2 (en) 1999-05-04 2000-11-09 Ortho-Clinical Diagnostics, Inc. Rapid and efficient capture of dna from sample without using cell lysing reagent
AUPQ495700A0 (en) * 2000-01-05 2000-02-03 Johnson & Johnson Research Pty. Limited Method for concurrent amplification and real time detection of polymorphic nucleic acid sequences
US7262006B1 (en) 2000-05-01 2007-08-28 Ortho-Clinical Diagnostics, Inc. Rapid and efficient capture of DNA from sample without using cell lysing reagent
CA2424584A1 (en) * 2000-10-02 2002-04-11 Ortho-Clinical Diagnostics, Inc. Detection of ras mutations
US7052837B2 (en) * 2001-03-13 2006-05-30 The Board Of Trustees Of The University Of Arkansas Histoplasma capsulatum catalase sequences and their use in the detection of Histoplamsa capsulatum and histoplasmosis
US20030162174A1 (en) * 2001-06-11 2003-08-28 Sutherland John W. Detecting nucleic acid deletion sequences
KR20040009054A (ko) * 2002-07-22 2004-01-31 김철욱 인적 유전인자의 개체별 특성파악을 위한 유전자 검사방법
US20040054160A1 (en) * 2002-09-16 2004-03-18 Santona Pal Nucleic-acid ink compositions for arraying onto a solid support
DE10315640A1 (de) * 2003-04-04 2004-10-14 Ignatov, Konstantin Verfahren zur kontrollierten Freisetzung von Komponenten in eine Lösung
WO2004106555A2 (en) * 2003-05-22 2004-12-09 Dow Agrosciences Llc High-throughput methods of screening dna for deletions and other mutations
TWI585411B (zh) * 2004-07-23 2017-06-01 太平洋愛吉生技股份有限公司 檢測膀胱癌之尿液標記物
US7902345B2 (en) 2006-12-05 2011-03-08 Sequenom, Inc. Detection and quantification of biomolecules using mass spectrometry
CN101641452B (zh) 2007-03-26 2013-10-23 塞昆纳姆股份有限公司 限制性核酸内切酶增强的多态序列检测
US8999634B2 (en) 2007-04-27 2015-04-07 Quest Diagnostics Investments Incorporated Nucleic acid detection combining amplification with fragmentation
US9689031B2 (en) 2007-07-14 2017-06-27 Ionian Technologies, Inc. Nicking and extension amplification reaction for the exponential amplification of nucleic acids
ATE549419T1 (de) 2007-08-29 2012-03-15 Sequenom Inc Verfahren und zusammensetzungen für die universelle grössenspezifische polymerasekettenreaktion
CN101280338B (zh) * 2007-12-13 2011-08-17 中国人民解放军第三军医大学第一附属医院 一种检测核酸多态性的核酸扩增方法
CA2718137A1 (en) * 2008-03-26 2009-10-01 Sequenom, Inc. Restriction endonuclease enhanced polymorphic sequence detection
WO2010107946A2 (en) * 2009-03-18 2010-09-23 Sequenom, Inc. Use of thermostable endonucleases for generating reporter molecules
WO2013003630A2 (en) * 2011-06-28 2013-01-03 Igor Kutyavin Methods and compositions for enrichment of nucleic acids in mixtures of highly homologous sequences
US9352312B2 (en) 2011-09-23 2016-05-31 Alere Switzerland Gmbh System and apparatus for reactions
CN105189746B (zh) 2013-03-14 2018-12-04 宝生物工程株式会社 用于使用耐热的错配内切核酸酶的方法
WO2016039377A1 (ja) 2014-09-11 2016-03-17 タカラバイオ株式会社 耐熱性のミスマッチエンドヌクレアーゼの利用方法
CN107614681A (zh) * 2015-03-20 2018-01-19 宝生物工程株式会社 用于检测靶核酸的高灵敏度方法
CN114014472B (zh) * 2022-01-07 2022-04-26 山东玲珑轮胎股份有限公司 一种废旧轮胎回收中产生的废水处理方法及系统

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1284931C (en) 1986-03-13 1991-06-18 Henry A. Erlich Process for detecting specific nucleotide variations and genetic polymorphisms present in nucleic acids
ES2092527T3 (es) 1990-06-08 1996-12-01 Behringwerke Ag Metodo para la determinacion cuantitativa de secuencias de adn.
US5455166A (en) * 1991-01-31 1995-10-03 Becton, Dickinson And Company Strand displacement amplification
AU652214B2 (en) * 1991-01-31 1994-08-18 Becton Dickinson & Company Strand displacement amplification "Sealing Clerk - sealing is to be refunded"
US5648211A (en) * 1994-04-18 1997-07-15 Becton, Dickinson And Company Strand displacement amplification using thermophilic enzymes
US5547861A (en) * 1994-04-18 1996-08-20 Becton, Dickinson And Company Detection of nucleic acid amplification
US5512441A (en) 1994-11-15 1996-04-30 American Health Foundation Quantative method for early detection of mutant alleles and diagnostic kits for carrying out the method

Also Published As

Publication number Publication date
CN1185181A (zh) 1998-06-17
EP0871767A1 (en) 1998-10-21
EP0871767A4 (en) 1999-09-01
KR19980703858A (ko) 1998-12-05
DE69619864T2 (de) 2002-11-07
EP0871767B1 (en) 2002-03-13
MX9707885A (es) 1998-06-28
JPH11503027A (ja) 1999-03-23
DK0871767T3 (da) 2002-07-08
CA2218026A1 (en) 1996-10-17
WO1996032500A1 (en) 1996-10-17
BR9604814A (pt) 2000-05-09
ZA962941B (en) 1996-12-04
ES2174063T3 (es) 2002-11-01
US6261768B1 (en) 2001-07-17
IL117884A0 (en) 1996-08-04
DE69619864D1 (de) 2002-04-18
ATE214429T1 (de) 2002-03-15
AR001619A1 (es) 1997-11-26
AUPN245295A0 (en) 1995-05-11

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