TW458981B - Gemcitabine derivatives - Google Patents

Gemcitabine derivatives Download PDF

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Publication number
TW458981B
TW458981B TW087103708A TW87103708A TW458981B TW 458981 B TW458981 B TW 458981B TW 087103708 A TW087103708 A TW 087103708A TW 87103708 A TW87103708 A TW 87103708A TW 458981 B TW458981 B TW 458981B
Authority
TW
Taiwan
Prior art keywords
king
special product
special
ministry
cns
Prior art date
Application number
TW087103708A
Other languages
English (en)
Chinese (zh)
Inventor
Finn Myhren
Bernt Borretzen
Are Dalen
Marit Liland Sandvold
Original Assignee
Norsk Hydro As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Norsk Hydro As filed Critical Norsk Hydro As
Application granted granted Critical
Publication of TW458981B publication Critical patent/TW458981B/zh

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06Pyrimidine radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
TW087103708A 1997-01-24 1998-03-13 Gemcitabine derivatives TW458981B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB9701427A GB2321454A (en) 1997-01-24 1997-01-24 Gemcitabine esters and amides

Publications (1)

Publication Number Publication Date
TW458981B true TW458981B (en) 2001-10-11

Family

ID=10806509

Family Applications (1)

Application Number Title Priority Date Filing Date
TW087103708A TW458981B (en) 1997-01-24 1998-03-13 Gemcitabine derivatives

Country Status (7)

Country Link
CZ (1) CZ293245B6 (es)
ES (1) ES2196528T3 (es)
GB (1) GB2321454A (es)
IL (1) IL130971A0 (es)
RU (1) RU2194711C2 (es)
TW (1) TW458981B (es)
ZA (1) ZA98576B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0420722D0 (en) * 2004-09-17 2004-10-20 Addex Pharmaceuticals Sa Novel allosteric modulators
ATE405573T1 (de) * 2004-12-17 2008-09-15 Lilly Co Eli Amid-prodrug von gemcitabin, zusammensetzungen und verwendung damit
AU2008354754B2 (en) * 2008-04-17 2014-09-11 The Johns Hopkins University On01910. Na enhances chemotherapeutic agent activity in drug-resistant tumors
BR112015010941A2 (pt) 2012-11-13 2017-07-11 Boyen Therapeutics Inc pró-fármacos de gemcitabina e suas utilizações
CN110713502A (zh) * 2019-11-29 2020-01-21 南京科技职业学院 一种吉西他滨杂质的合成方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL89258A0 (en) * 1988-02-16 1989-09-10 Lilly Co Eli 2',3'-dideoxy-2',2'-difluoro-nucleosides
YU43193A (sh) * 1992-06-22 1997-01-08 Eli Lilly And Company 2'-deoksi-2',2'-difluoro(4-supstituisani)pirimidinski nukleozidi antivirusnog i antikancerogenog dejstva i međuproizvodi

Also Published As

Publication number Publication date
ZA98576B (en) 1998-07-23
IL130971A0 (en) 2001-01-28
RU2194711C2 (ru) 2002-12-20
GB9701427D0 (en) 1997-03-12
ES2196528T3 (es) 2003-12-16
GB2321454A (en) 1998-07-29
CZ293245B6 (cs) 2004-03-17
CZ247999A3 (cs) 1999-12-15

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