TW224098B - - Google Patents
Info
- Publication number
- TW224098B TW224098B TW082101987A TW82101987A TW224098B TW 224098 B TW224098 B TW 224098B TW 082101987 A TW082101987 A TW 082101987A TW 82101987 A TW82101987 A TW 82101987A TW 224098 B TW224098 B TW 224098B
- Authority
- TW
- Taiwan
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/856,611 US5196424A (en) | 1992-03-24 | 1992-03-24 | N-[2-amino-4-substituted[[(pyrrollo or pyrido)[2,3-d]pyrimidinyl]-alkyl]benzoyl]-L-glutamic acids |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TW224098B true TW224098B (enExample) | 1994-05-21 |
Family
ID=25324069
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW082101987A TW224098B (enExample) | 1992-03-24 | 1993-03-18 |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US5196424A (enExample) |
| EP (1) | EP0567223A1 (enExample) |
| JP (1) | JPH0625246A (enExample) |
| KR (1) | KR930019676A (enExample) |
| CN (1) | CN1078235A (enExample) |
| AU (1) | AU3542993A (enExample) |
| BR (1) | BR9301273A (enExample) |
| CA (1) | CA2091978A1 (enExample) |
| CZ (1) | CZ44093A3 (enExample) |
| FI (1) | FI931251A7 (enExample) |
| HU (1) | HUT70036A (enExample) |
| IL (1) | IL105100A0 (enExample) |
| MX (1) | MX9301544A (enExample) |
| MY (1) | MY131322A (enExample) |
| NO (1) | NO931008L (enExample) |
| NZ (1) | NZ247193A (enExample) |
| TW (1) | TW224098B (enExample) |
| ZA (1) | ZA931944B (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5457056A (en) * | 1993-07-06 | 1995-10-10 | Fiberchem, Inc. | Halohydrocarbon sensing chemistry with base modifier |
| US6537999B2 (en) * | 1996-06-06 | 2003-03-25 | Duquesne University Of The Holy Ghost | Pyrimidine derivatives and methods of making and using these derivatives |
| EP0923287A4 (en) * | 1996-08-30 | 2001-08-01 | Lilly Co Eli | NON-CLASSIC PYRROLO (2,3-D) PYRIMIDINE ANTIFOLATE |
| EP1554572B1 (en) | 2001-07-25 | 2009-10-14 | Raptor Pharmaceutical Inc. | Compositions and methods for modulating blood-brain barrier transport |
| US8030319B2 (en) * | 2005-02-10 | 2011-10-04 | Duquesne University Of The Holy Ghost | Methods for treating cancer and other pathological proliferating disorders by inhibiting mitosis using pyrrolo[2 3-d]pyrimidines |
| DK1889198T3 (da) | 2005-04-28 | 2015-02-09 | Proteus Digital Health Inc | Farma-informatiksystem |
| CN1962658B (zh) * | 2005-11-10 | 2010-05-12 | 北京大学 | 一种四氢吡啶并[3,2-d]嘧啶类化合物及制备抗肿瘤药物的用途 |
| KR20090071598A (ko) | 2006-09-18 | 2009-07-01 | 랩터 파마슈티컬 인코포레이티드 | 수용체 결합 단백질(ｒａｐ)-접합체 투여에 의한 간 질환의 치료 |
| WO2010095940A2 (en) | 2009-02-20 | 2010-08-26 | To-Bbb Holding B.V. | Glutathione-based drug delivery system |
| TWI556839B (zh) | 2009-05-06 | 2016-11-11 | 研究室護膚股份有限公司 | 包含活性劑－磷酸鈣粒子複合物之皮膚遞送組成物及其使用方法 |
| WO2011056957A2 (en) * | 2009-11-06 | 2011-05-12 | Chelsea Therapeutics, Inc. | Enzyme inhibiting compounds |
| US20120077778A1 (en) | 2010-09-29 | 2012-03-29 | Andrea Bourdelais | Ladder-Frame Polyether Conjugates |
| CN102977107B (zh) * | 2012-12-25 | 2015-04-22 | 山西普德药业股份有限公司 | 一种培美曲塞二钠化合物及其组合物 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS59170091A (ja) * | 1983-03-17 | 1984-09-26 | Takeda Chem Ind Ltd | ６−チオ−７−デアザプリン誘導体およびその製造法 |
| EP0119591B1 (en) * | 1983-03-17 | 1988-06-22 | Takeda Chemical Industries, Ltd. | Thiodeazapurine derivatives |
| GB2160525B (en) * | 1983-12-27 | 1987-08-26 | Stanford Res Inst Int | 8,10-dideazaminopterins |
| US5026851A (en) * | 1985-03-08 | 1991-06-25 | The Trustees Of Princeton University | Pyrido[2,3-]pyrimidine derivatives |
| US4684653A (en) * | 1985-03-08 | 1987-08-04 | The Trustees Of Princeton University | Pyrido(2,3-d)pyrimidine derivatives |
| ZA861235B (en) * | 1985-03-08 | 1986-10-29 | Univ Princeton | Pyrido(2,3-d)pyrimidine derivatives |
| US4927828A (en) * | 1985-03-08 | 1990-05-22 | The Trustees Of Princeton University | Diastereoisomeric tetrahydropyrido-(2,3,d) pyrimidine derivatives |
| US4923872A (en) * | 1986-08-26 | 1990-05-08 | Warner-Lambert Co. | Analogues of pyrrolo[3,2d]pyrimidin-4-ones |
| US4988702A (en) * | 1986-08-26 | 1991-01-29 | Warner-Lambert Company | Novel 9-deazaguanines |
| US4902796A (en) * | 1986-10-20 | 1990-02-20 | The Trustees Of Princeton University | 6-alkenyl and ethynyl derivatives of 2-amino-4-hydroxypyrido[2,3-d]pyrimidines |
| US4988813A (en) * | 1986-10-20 | 1991-01-29 | The Trustees Of Princeton University | Process for the preparation of fused pyridine compounds |
| US4921858A (en) * | 1986-10-24 | 1990-05-01 | Warner-Lambert Company | 7-deazaguanines as immunomodulators |
| JP2830008B2 (ja) * | 1988-04-01 | 1998-12-02 | 武田薬品工業株式会社 | 縮合ピリミジン誘導体 |
| NO169490C (no) * | 1988-03-24 | 1992-07-01 | Takeda Chemical Industries Ltd | Analogifremgangsmaate for fremstilling av terapeutisk aktive pyrrolopyrimidinderivater |
| US4882333A (en) * | 1988-05-25 | 1989-11-21 | The Trustess Of Princeton University | N-(5,6,7,8-tetrahydropyrido[2,3-d]pyrimidin-6-yl-alkanoyl)-glutamic acid derivatives |
| CH677140A5 (enExample) * | 1988-10-11 | 1991-04-15 | W & E Umwelttechnik Ag | |
| WO1991004254A1 (en) * | 1989-09-19 | 1991-04-04 | Teijin Limited | PYRROLO[2,3-d]PYRIMIDINE DERIVATIVE, PROCESS FOR PREPARING THE SAME, AND PHARMACEUTICAL PREPARATION COMPRISING THE DERIVATIVE AS ACTIVE INGREDIENT |
| CA2032695A1 (en) * | 1989-12-20 | 1991-06-21 | Hiroshi Akimoto | Condensed heterocyclic compounds, their production and use |
-
1992
- 1992-03-24 US US07/856,611 patent/US5196424A/en not_active Expired - Fee Related
-
1993
- 1993-03-18 TW TW082101987A patent/TW224098B/zh active
- 1993-03-18 CA CA002091978A patent/CA2091978A1/en not_active Abandoned
- 1993-03-18 MY MYPI93000474A patent/MY131322A/en unknown
- 1993-03-18 IL IL105100A patent/IL105100A0/xx unknown
- 1993-03-18 NZ NZ247193A patent/NZ247193A/en unknown
- 1993-03-18 EP EP93302063A patent/EP0567223A1/en not_active Withdrawn
- 1993-03-18 ZA ZA931944A patent/ZA931944B/xx unknown
- 1993-03-18 CZ CZ93440A patent/CZ44093A3/cs unknown
- 1993-03-19 MX MX9301544A patent/MX9301544A/es unknown
- 1993-03-19 HU HU9300804A patent/HUT70036A/hu unknown
- 1993-03-19 NO NO93931008A patent/NO931008L/no unknown
- 1993-03-22 KR KR1019930004440A patent/KR930019676A/ko not_active Withdrawn
- 1993-03-22 FI FI931251A patent/FI931251A7/fi not_active Application Discontinuation
- 1993-03-23 JP JP5063819A patent/JPH0625246A/ja active Pending
- 1993-03-23 AU AU35429/93A patent/AU3542993A/en not_active Abandoned
- 1993-03-23 CN CN93103205A patent/CN1078235A/zh not_active Withdrawn
- 1993-03-23 BR BR9301273A patent/BR9301273A/pt not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| MX9301544A (es) | 1994-07-29 |
| HUT70036A (en) | 1995-09-28 |
| CN1078235A (zh) | 1993-11-10 |
| CZ44093A3 (en) | 1994-02-16 |
| FI931251L (fi) | 1993-09-25 |
| JPH0625246A (ja) | 1994-02-01 |
| AU3542993A (en) | 1993-09-30 |
| CA2091978A1 (en) | 1993-09-25 |
| IL105100A0 (en) | 1993-12-28 |
| NO931008D0 (no) | 1993-03-19 |
| HU9300804D0 (en) | 1993-06-28 |
| BR9301273A (pt) | 1993-09-28 |
| NO931008L (no) | 1993-09-27 |
| KR930019676A (ko) | 1993-10-18 |
| EP0567223A1 (en) | 1993-10-27 |
| FI931251A0 (fi) | 1993-03-22 |
| NZ247193A (en) | 1995-05-26 |
| ZA931944B (en) | 1994-09-18 |
| MY131322A (en) | 2007-08-30 |
| FI931251A7 (fi) | 1993-09-25 |
| US5196424A (en) | 1993-03-23 |