TW202204611A - 基因組修飾方法及基因組修飾套組 - Google Patents

基因組修飾方法及基因組修飾套組 Download PDF

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TW202204611A
TW202204611A TW110112407A TW110112407A TW202204611A TW 202204611 A TW202204611 A TW 202204611A TW 110112407 A TW110112407 A TW 110112407A TW 110112407 A TW110112407 A TW 110112407A TW 202204611 A TW202204611 A TW 202204611A
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sequence
homology arm
genes
selectable marker
nucleotide sequence
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TW110112407A
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Chinese (zh)
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相澤康則
大野知幸
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日商羅格米克斯股份有限公司
國立大學法人東京工業大學
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Publication of TW202204611A publication Critical patent/TW202204611A/zh

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TW110112407A 2020-04-06 2021-04-06 基因組修飾方法及基因組修飾套組 TW202204611A (zh)

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JP2020068266 2020-04-06
JP2020-068266 2020-04-06
JP2020141335 2020-08-25
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US (1) US20230147287A1 (https=)
EP (1) EP4134431A4 (https=)
JP (1) JP7825830B2 (https=)
KR (1) KR20220164748A (https=)
CN (1) CN115552002A (https=)
AU (1) AU2021254373A1 (https=)
CA (1) CA3179410A1 (https=)
IL (1) IL297078A (https=)
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CN119072544A (zh) 2022-04-01 2024-12-03 株式会社标志融合 适合于基因工程、细胞工程和细胞药物的细胞及其制造方法
JP7212982B1 (ja) 2022-10-05 2023-01-26 株式会社Logomix 細胞ライブラリおよびその製造方法
WO2024219474A1 (ja) * 2023-04-21 2024-10-24 株式会社Logomix Ｋｉｒ遺伝子クラスター領域、ｌｉｌｒ遺伝子クラスター領域およびｋｌｒ遺伝子クラスター領域のいずれか１以上の領域において欠失を有する細胞およびその製造方法
WO2025033445A1 (ja) 2023-08-07 2025-02-13 株式会社Logomix 遺伝子をコンディショナルに不活化させる方法、およびそのための細胞

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CN102094036A (zh) * 2010-12-13 2011-06-15 西北农林科技大学 一种等位基因双敲除打靶载体系统及其构建方法
US8697359B1 (en) 2012-12-12 2014-04-15 The Broad Institute, Inc. CRISPR-Cas systems and methods for altering expression of gene products
CN105263312A (zh) * 2013-04-05 2016-01-20 美国陶氏益农公司 用于在植物基因组内整合外源序列的方法和组合物
US10787684B2 (en) * 2013-11-19 2020-09-29 President And Fellows Of Harvard College Large gene excision and insertion
KR102170502B1 (ko) * 2013-12-11 2020-10-28 리제너론 파마슈티칼스 인코포레이티드 게놈의 표적화된 변형을 위한 방법 및 조성물
WO2017191503A1 (en) * 2016-05-05 2017-11-09 Crispr Therapeutics Ag Materials and methods for treatment of hemoglobinopathies
CN106520829B (zh) * 2016-10-17 2019-12-17 扬州大学 一种终止双等位基因转录的方法
JP7466905B2 (ja) * 2017-07-18 2024-04-15 ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー 二段階相同組換え修復によるスカーレスゲノム編集
WO2019216338A1 (ja) * 2018-05-08 2019-11-14 国立大学法人大阪大学 ホモ接合型細胞の作製方法

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AU2021254373A1 (en) 2022-11-03
EP4134431A4 (en) 2024-06-05
US20230147287A1 (en) 2023-05-11
CN115552002A (zh) 2022-12-30
JP7825830B2 (ja) 2026-03-09
EP4134431A1 (en) 2023-02-15
IL297078A (en) 2022-12-01
JPWO2021206054A1 (https=) 2021-10-14
WO2021206054A1 (ja) 2021-10-14
CA3179410A1 (en) 2021-10-14
KR20220164748A (ko) 2022-12-13

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