KR20220164748A - 게놈 개변 방법 및 게놈 개변 키트 - Google Patents
게놈 개변 방법 및 게놈 개변 키트 Download PDFInfo
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- KR20220164748A KR20220164748A KR1020227038024A KR20227038024A KR20220164748A KR 20220164748 A KR20220164748 A KR 20220164748A KR 1020227038024 A KR1020227038024 A KR 1020227038024A KR 20227038024 A KR20227038024 A KR 20227038024A KR 20220164748 A KR20220164748 A KR 20220164748A
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
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- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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- C12N15/09—Recombinant DNA-technology
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- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1135—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against oncogenes or tumor suppressor genes
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- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1138—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against receptors or cell surface proteins
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- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
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- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/90—Stable introduction of foreign DNA into chromosome
- C12N15/902—Stable introduction of foreign DNA into chromosome using homologous recombination
- C12N15/905—Stable introduction of foreign DNA into chromosome using homologous recombination in yeast
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/90—Stable introduction of foreign DNA into chromosome
- C12N15/902—Stable introduction of foreign DNA into chromosome using homologous recombination
- C12N15/907—Stable introduction of foreign DNA into chromosome using homologous recombination in mammalian cells
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- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
- C12N9/22—Ribonucleases [RNase]; Deoxyribonucleases [DNase]
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- C12Y201/00—Transferases transferring one-carbon groups (2.1)
- C12Y201/01—Methyltransferases (2.1.1)
- C12Y201/01107—Uroporphyrinogen-III C-methyltransferase (2.1.1.107)
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- C12N2310/00—Structure or type of the nucleic acid
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- C12N2310/20—Type of nucleic acid involving clustered regularly interspaced short palindromic repeats [CRISPR]
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- C12N2800/00—Nucleic acids vectors
- C12N2800/80—Vectors containing sites for inducing double-stranded breaks, e.g. meganuclease restriction sites
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- Wood Science & Technology (AREA)
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- Plant Pathology (AREA)
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- Cell Biology (AREA)
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- Crystallography & Structural Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
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- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2020068266 | 2020-04-06 | ||
| JPJP-P-2020-068266 | 2020-04-06 | ||
| JPJP-P-2020-141335 | 2020-08-25 | ||
| JP2020141335 | 2020-08-25 | ||
| PCT/JP2021/014495 WO2021206054A1 (ja) | 2020-04-06 | 2021-04-05 | ゲノム改変方法及びゲノム改変キット |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20220164748A true KR20220164748A (ko) | 2022-12-13 |
Family
ID=78022517
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020227038024A Pending KR20220164748A (ko) | 2020-04-06 | 2021-04-05 | 게놈 개변 방법 및 게놈 개변 키트 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20230147287A1 (https=) |
| EP (1) | EP4134431A4 (https=) |
| JP (1) | JP7825830B2 (https=) |
| KR (1) | KR20220164748A (https=) |
| CN (1) | CN115552002A (https=) |
| AU (1) | AU2021254373A1 (https=) |
| CA (1) | CA3179410A1 (https=) |
| IL (1) | IL297078A (https=) |
| TW (1) | TW202204611A (https=) |
| WO (1) | WO2021206054A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN119072544A (zh) | 2022-04-01 | 2024-12-03 | 株式会社标志融合 | 适合于基因工程、细胞工程和细胞药物的细胞及其制造方法 |
| JP7212982B1 (ja) | 2022-10-05 | 2023-01-26 | 株式会社Logomix | 細胞ライブラリおよびその製造方法 |
| WO2024219474A1 (ja) * | 2023-04-21 | 2024-10-24 | 株式会社Logomix | Kir遺伝子クラスター領域、lilr遺伝子クラスター領域およびklr遺伝子クラスター領域のいずれか1以上の領域において欠失を有する細胞およびその製造方法 |
| WO2025033445A1 (ja) | 2023-08-07 | 2025-02-13 | 株式会社Logomix | 遺伝子をコンディショナルに不活化させる方法、およびそのための細胞 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014093661A2 (en) | 2012-12-12 | 2014-06-19 | The Broad Institute, Inc. | Crispr-cas systems and methods for altering expression of gene products |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102094036A (zh) * | 2010-12-13 | 2011-06-15 | 西北农林科技大学 | 一种等位基因双敲除打靶载体系统及其构建方法 |
| CN105263312A (zh) * | 2013-04-05 | 2016-01-20 | 美国陶氏益农公司 | 用于在植物基因组内整合外源序列的方法和组合物 |
| US10787684B2 (en) * | 2013-11-19 | 2020-09-29 | President And Fellows Of Harvard College | Large gene excision and insertion |
| KR102170502B1 (ko) * | 2013-12-11 | 2020-10-28 | 리제너론 파마슈티칼스 인코포레이티드 | 게놈의 표적화된 변형을 위한 방법 및 조성물 |
| WO2017191503A1 (en) * | 2016-05-05 | 2017-11-09 | Crispr Therapeutics Ag | Materials and methods for treatment of hemoglobinopathies |
| CN106520829B (zh) * | 2016-10-17 | 2019-12-17 | 扬州大学 | 一种终止双等位基因转录的方法 |
| JP7466905B2 (ja) * | 2017-07-18 | 2024-04-15 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | 二段階相同組換え修復によるスカーレスゲノム編集 |
| WO2019216338A1 (ja) * | 2018-05-08 | 2019-11-14 | 国立大学法人大阪大学 | ホモ接合型細胞の作製方法 |
-
2021
- 2021-04-05 CN CN202180026858.3A patent/CN115552002A/zh active Pending
- 2021-04-05 JP JP2022514064A patent/JP7825830B2/ja active Active
- 2021-04-05 EP EP21785350.6A patent/EP4134431A4/en active Pending
- 2021-04-05 WO PCT/JP2021/014495 patent/WO2021206054A1/ja not_active Ceased
- 2021-04-05 IL IL297078A patent/IL297078A/en unknown
- 2021-04-05 AU AU2021254373A patent/AU2021254373A1/en active Pending
- 2021-04-05 US US17/917,188 patent/US20230147287A1/en active Pending
- 2021-04-05 KR KR1020227038024A patent/KR20220164748A/ko active Pending
- 2021-04-05 CA CA3179410A patent/CA3179410A1/en active Pending
- 2021-04-06 TW TW110112407A patent/TW202204611A/zh unknown
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014093661A2 (en) | 2012-12-12 | 2014-06-19 | The Broad Institute, Inc. | Crispr-cas systems and methods for altering expression of gene products |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2021254373A1 (en) | 2022-11-03 |
| TW202204611A (zh) | 2022-02-01 |
| EP4134431A4 (en) | 2024-06-05 |
| US20230147287A1 (en) | 2023-05-11 |
| CN115552002A (zh) | 2022-12-30 |
| JP7825830B2 (ja) | 2026-03-09 |
| EP4134431A1 (en) | 2023-02-15 |
| IL297078A (en) | 2022-12-01 |
| JPWO2021206054A1 (https=) | 2021-10-14 |
| WO2021206054A1 (ja) | 2021-10-14 |
| CA3179410A1 (en) | 2021-10-14 |
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