TW202107067A - 併合光學系統 - Google Patents

併合光學系統 Download PDF

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Publication number
TW202107067A
TW202107067A TW109113755A TW109113755A TW202107067A TW 202107067 A TW202107067 A TW 202107067A TW 109113755 A TW109113755 A TW 109113755A TW 109113755 A TW109113755 A TW 109113755A TW 202107067 A TW202107067 A TW 202107067A
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TW
Taiwan
Prior art keywords
light
wavelength range
cars
target
optical
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TW109113755A
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English (en)
Chinese (zh)
Inventor
盧卡斯 布魯克納
大衛 安德森
普拉卡什史帝德哈爾 穆爾帝
Original Assignee
日商亞多納富有限公司
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Publication of TW202107067A publication Critical patent/TW202107067A/zh

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/65—Raman scattering
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/02—Details
    • G01J3/0205—Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0062—Arrangements for scanning
    • A61B5/0066—Optical coherence imaging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0073—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by tomography, i.e. reconstruction of 3D images from 2D projections
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0075—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by spectroscopy, i.e. measuring spectra, e.g. Raman spectroscopy, infrared absorption spectroscopy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/14551—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01B—MEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
    • G01B9/00—Measuring instruments characterised by the use of optical techniques
    • G01B9/02—Interferometers
    • G01B9/0209—Low-coherence interferometers
    • G01B9/02091—Tomographic interferometers, e.g. based on optical coherence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/02—Details
    • G01J3/10—Arrangements of light sources specially adapted for spectrometry or colorimetry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/28—Investigating the spectrum
    • G01J3/44—Raman spectrometry; Scattering spectrometry ; Fluorescence spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G01N21/4795—Scattering, i.e. diffuse reflection spatially resolved investigating of object in scattering medium
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/06—Means for illuminating specimens
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/16—Microscopes adapted for ultraviolet illumination ; Fluorescence microscopes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/65—Raman scattering
    • G01N2021/653—Coherent methods [CARS]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/06—Illumination; Optics
    • G01N2201/061—Sources
    • G01N2201/06113—Coherent sources; lasers

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  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Pathology (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Surgery (AREA)
  • Optics & Photonics (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Radiology & Medical Imaging (AREA)
  • Emergency Medicine (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
TW109113755A 2019-04-29 2020-04-24 併合光學系統 TW202107067A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962840001P 2019-04-29 2019-04-29
US62/840,001 2019-04-29

Publications (1)

Publication Number Publication Date
TW202107067A true TW202107067A (zh) 2021-02-16

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
TW109113755A TW202107067A (zh) 2019-04-29 2020-04-24 併合光學系統

Country Status (6)

Country Link
US (2) US11944407B2 (enExample)
JP (3) JP6887708B1 (enExample)
KR (1) KR20220005449A (enExample)
CN (1) CN113631897B (enExample)
TW (1) TW202107067A (enExample)
WO (1) WO2020222300A1 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20220005449A (ko) * 2019-04-29 2022-01-13 아토나프 가부시키가이샤 하이브리드 광학 시스템
JP7565554B2 (ja) * 2020-05-22 2024-10-11 国立大学法人山梨大学 分光計、分析システム及び分析方法
US20240167958A1 (en) * 2021-04-22 2024-05-23 Atonarp Inc. Method and system for acquiring cars spectrum
JP7577388B2 (ja) * 2021-08-20 2024-11-05 アトナープ株式会社 Ｃａｒｓスペクトルを取得するための方法およびシステム
CN117881957A (zh) * 2021-08-31 2024-04-12 株式会社岛津制作所 拉曼分光装置
WO2023058710A1 (en) * 2021-10-06 2023-04-13 Atonarp Inc. Method and system for acquiring cars spectrum
WO2023063415A1 (en) * 2021-10-14 2023-04-20 Atonarp Inc. System including a laser module
CN114795120B (zh) * 2021-11-22 2025-10-31 北京航空航天大学 一种多模态成像装置
KR102753085B1 (ko) * 2021-12-27 2025-01-10 고려대학교 산학협력단 광대역 비표지 분자 이미징 시스템
KR20240169663A (ko) * 2022-03-31 2024-12-03 온투 이노베이션 아이엔씨. 다중 파장 레이저 음향을 사용하여 샘플의 특성화를 수행하기 위한 시스템 및 방법
GB202212043D0 (en) * 2022-08-18 2022-10-05 Univ Of Lancaster Glucose concentration measuring device

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EP1754033B1 (en) * 2004-05-27 2011-06-22 Yeda Research And Development Co., Ltd. Coherently controlled nonlinear raman spectroscopy
JP5100461B2 (ja) 2008-03-14 2012-12-19 英明 加納 非線形分光計測システム用の光源装置、非線形分光計測システム及び方法
JP2009258071A (ja) * 2008-03-28 2009-11-05 Fujifilm Corp 粒子分析装置および粒子分析方法
JP2010002256A (ja) 2008-06-19 2010-01-07 Fujifilm Corp 非線形ラマン散乱光測定装置
US9285575B2 (en) * 2009-01-26 2016-03-15 President And Fellows Of Harvard College Systems and methods for selective detection and imaging in coherent Raman microscopy by spectral excitation shaping
GB0904739D0 (en) 2009-03-19 2009-05-06 Univ Cardiff Coherent anti-stokes raman spectroscopy
JP5444457B2 (ja) * 2009-05-11 2014-03-19 コリア リサーチ インスティテュート オブ スタンダーズ アンド サイエンス 非線形光学顕微鏡を用いた血管内脂質の非破壊的病理的変化診断プログラム
US8553219B2 (en) * 2011-01-24 2013-10-08 Vanderbilt University Common detector for combined raman spectroscopy-optical coherence tomography
WO2013047698A1 (ja) * 2011-09-30 2013-04-04 学校法人東京理科大学 光干渉計、情報取得装置、及び情報取得方法
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JP5996665B2 (ja) 2012-10-19 2016-09-21 株式会社日立製作所 Ｃａｒｓ顕微鏡
WO2014180986A1 (en) * 2013-05-10 2014-11-13 Ludwig-Maximilians-Universität München A system and method for stimulated raman spectroscopy
EP2806263A1 (en) 2013-05-24 2014-11-26 Nederlandse Organisatie voor toegepast -natuurwetenschappelijk onderzoek TNO Method and detector for detecting an analyte
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Also Published As

Publication number Publication date
JP6887708B1 (ja) 2021-06-16
JP2021519437A (ja) 2021-08-10
US20220087530A1 (en) 2022-03-24
WO2020222300A1 (en) 2020-11-05
US11944407B2 (en) 2024-04-02
KR20220005449A (ko) 2022-01-13
JP2024079850A (ja) 2024-06-11
US12343113B2 (en) 2025-07-01
CN113631897B (zh) 2024-07-16
JP2021113831A (ja) 2021-08-05
CN113631897A (zh) 2021-11-09
JP7477882B2 (ja) 2024-05-02
US20240197182A1 (en) 2024-06-20

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