TW202011029A - 偵測及定量fgf21之方法 - Google Patents

偵測及定量fgf21之方法 Download PDF

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Publication number
TW202011029A
TW202011029A TW108112039A TW108112039A TW202011029A TW 202011029 A TW202011029 A TW 202011029A TW 108112039 A TW108112039 A TW 108112039A TW 108112039 A TW108112039 A TW 108112039A TW 202011029 A TW202011029 A TW 202011029A
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amino acid
seq
acid sequence
conservative substitutions
antibody
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TW108112039A
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English (en)
Chinese (zh)
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約翰 學 寧 劉
純一郎 園田
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美商建南德克公司
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/577—Immunoassay; Biospecific binding assay; Materials therefor involving monoclonal antibodies binding reaction mechanisms characterised by the use of monoclonal antibodies
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/26—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/557—Immunoassay; Biospecific binding assay; Materials therefor using kinetic measurement, i.e. time rate of progress of an antigen-antibody interaction
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/475—Assays involving growth factors
    • G01N2333/50—Fibroblast growth factors [FGF]

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Endocrinology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
TW108112039A 2018-04-04 2019-04-03 偵測及定量fgf21之方法 TW202011029A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862652701P 2018-04-04 2018-04-04
US62/652,701 2018-04-04

Publications (1)

Publication Number Publication Date
TW202011029A true TW202011029A (zh) 2020-03-16

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ID=66248681

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TW108112039A TW202011029A (zh) 2018-04-04 2019-04-03 偵測及定量fgf21之方法

Country Status (12)

Country Link
US (1) US20210025890A1 (https=)
EP (1) EP3775930A1 (https=)
JP (1) JP2021520492A (https=)
KR (1) KR20200140852A (https=)
CN (1) CN112005119A (https=)
AU (1) AU2019247778A1 (https=)
BR (1) BR112020019756A2 (https=)
CA (1) CA3092388A1 (https=)
IL (1) IL277726A (https=)
MX (1) MX2020010387A (https=)
TW (1) TW202011029A (https=)
WO (1) WO2019195514A1 (https=)

Families Citing this family (10)

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WO2013006486A2 (en) 2011-07-01 2013-01-10 Ngm Biopharmaceuticals, Inc. Compositions, uses and methods for treatment of metabolic disorders and diseases
US9290557B2 (en) 2012-11-28 2016-03-22 Ngm Biopharmaceuticals, Inc. Compositions comprising variants and fusions of FGF19 polypeptides
US9273107B2 (en) 2012-12-27 2016-03-01 Ngm Biopharmaceuticals, Inc. Uses and methods for modulating bile acid homeostasis and treatment of bile acid disorders and diseases
EP3503882A4 (en) 2016-08-26 2020-07-29 NGM Biopharmaceuticals, Inc. METHOD FOR TREATING FIBROBLAST GROWTH FACTOR-19-MEDIATED CARCINOMAS AND TUMORS
WO2021092140A1 (en) * 2019-11-06 2021-05-14 Ngm Biopharmaceuticals, Inc. Methods of reducing lactate in liver disease patients using variants and fusions of fgf19/fgf21 polypeptides
CN110954693A (zh) * 2019-11-29 2020-04-03 郑州大学 一种肿瘤标志物Cyfra21-1的Simoa试剂盒及其应用
CN112255415A (zh) * 2020-09-10 2021-01-22 温州医科大学 食蟹猴血清中fgf-21浓度的检测方法
CN113030469B (zh) * 2021-03-18 2024-04-09 贵州省分析测试研究院 一种新型冠状病毒检测方法
WO2022218277A1 (zh) * 2021-04-13 2022-10-20 广东东阳光药业有限公司 一种抗fgf21羧基末端的抗体及其应用
CN118294677A (zh) * 2024-04-12 2024-07-05 杭州戴格生物技术有限公司 一种检测成纤维细胞生长因子21的方法

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Publication number Publication date
MX2020010387A (es) 2020-10-22
CN112005119A (zh) 2020-11-27
IL277726A (en) 2020-11-30
WO2019195514A1 (en) 2019-10-10
KR20200140852A (ko) 2020-12-16
JP2021520492A (ja) 2021-08-19
BR112020019756A2 (pt) 2021-01-26
CA3092388A1 (en) 2019-10-10
US20210025890A1 (en) 2021-01-28
EP3775930A1 (en) 2021-02-17
AU2019247778A1 (en) 2020-11-19

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