TW201111781A - Novel anti-cMET antibody and its use for the detection and the diagnostic of cancer - Google Patents
Novel anti-cMET antibody and its use for the detection and the diagnostic of cancer Download PDFInfo
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| EP09305777A EP2287197A1 (en) | 2009-08-21 | 2009-08-21 | Anti-cMET antibody and its use for the detection and the diagnosis of cancer |
| US34800510P | 2010-05-25 | 2010-05-25 |
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| EP2287197A1 (en) * | 2009-08-21 | 2011-02-23 | Pierre Fabre Medicament | Anti-cMET antibody and its use for the detection and the diagnosis of cancer |
| EP3264089A1 (en) | 2010-08-31 | 2018-01-03 | Genentech, Inc. | Biomarkers and methods of treatment |
| KR101444837B1 (ko) * | 2011-06-03 | 2014-09-30 | 한국생명공학연구원 | ＨＧＦ 활성을 가지는 ｃ-Ｍｅｔ에 대한 인간항체 및 이의 용도 |
| KR20140064971A (ko) | 2011-09-19 | 2014-05-28 | 제넨테크, 인크. | c-met 길항제 및 B-raf 길항제를 포함하는 조합 치료 |
| KR20130036993A (ko) * | 2011-10-05 | 2013-04-15 | 삼성전자주식회사 | ｃ-Ｍｅｔ의 ＳＥＭＡ 도메인 내의 에피토프에 특이적으로 결합하는 항체 |
| AU2012340826A1 (en) | 2011-11-21 | 2014-05-29 | Genentech, Inc. | Purification of anti-c-met antibodies |
| WO2013078145A1 (en) * | 2011-11-21 | 2013-05-30 | Taivex Therapeutics Corporation | Biomarkers for cancers responsive to modulators of hec1 activity |
| GB201121914D0 (en) | 2011-12-20 | 2012-02-01 | Ge Healthcare Ltd | Method for patient selection |
| EP2870178B1 (en) * | 2012-05-09 | 2017-07-12 | Eli Lilly and Company | Anti-c-met antibodies |
| WO2013192594A2 (en) * | 2012-06-21 | 2013-12-27 | Sorrento Therapeutics Inc. | Antigen binding proteins that bind c-met |
| CN104994879A (zh) | 2013-02-22 | 2015-10-21 | 霍夫曼-拉罗奇有限公司 | 治疗癌症和预防药物抗性的方法 |
| US10214593B2 (en) | 2013-04-02 | 2019-02-26 | Samsung Electronics Co., Ltd. | Anti-idiotype antibody against anti-c-MET antibody |
| GB201314936D0 (en) | 2013-08-21 | 2013-10-02 | Ge Healthcare Ltd | Radiolabelling method |
| WO2015031614A1 (en) * | 2013-08-28 | 2015-03-05 | Abbvie Inc. | Soluble cmet assay |
| WO2015031626A1 (en) * | 2013-08-28 | 2015-03-05 | Abbvie Inc. | Soluble cmet assay |
| WO2015032695A1 (en) * | 2013-09-09 | 2015-03-12 | Ventana Medical Systems, Inc. | Scoring method for mesothelin protein expression |
| GB201322456D0 (en) | 2013-12-18 | 2014-02-05 | Ge Healthcare Ltd | Radiotracer compositions and methods |
| EP3122900A1 (en) * | 2014-03-24 | 2017-02-01 | F. Hoffmann-La Roche AG | Cancer treatment with c-met antagonists and correlation of the latter with hgf expression |
| JP2017524371A (ja) | 2014-05-23 | 2017-08-31 | ジェネンテック， インコーポレイテッド | Ｍｉｔバイオマーカーとその使用方法 |
| ES2764299T3 (es) | 2014-12-09 | 2020-06-02 | Inst Nat Sante Rech Med | Anticuerpos monoclonales humanos contra AXL |
| WO2016124568A1 (en) * | 2015-02-03 | 2016-08-11 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Anti-rho gtpase conformational single domain antibodies and uses thereof |
| WO2016135041A1 (en) | 2015-02-26 | 2016-09-01 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Fusion proteins and antibodies comprising thereof for promoting apoptosis |
| DK3270965T3 (da) * | 2015-03-18 | 2020-06-08 | Seattle Genetics Inc | Cd48-antistoffer og konjugater deraf |
| ES2896709T3 (es) | 2016-02-05 | 2022-02-25 | Helixmith Co Ltd | Anticuerpos anti-c-Met y usos de los mismos |
| KR20230028574A (ko) | 2016-05-17 | 2023-02-28 | 애브비 바이오테라퓨틱스 인크. | 항-cMet 항체 약물 컨쥬게이트 및 그들의 이용 방법 |
| TWI782930B (zh) | 2016-11-16 | 2022-11-11 | 美商再生元醫藥公司 | 抗ｍｅｔ抗體，結合ｍｅｔ之雙特異性抗原結合分子及其使用方法 |
| RU2735918C2 (ru) * | 2018-06-07 | 2020-11-10 | Общество с ограниченной ответственностью "ДЖЕЙВИС ДИАГНОСТИКС" | Набор реагентов для выявления маркера эпителиальных карцином |
| WO2020001526A1 (zh) * | 2018-06-29 | 2020-01-02 | 苏州智核生物医药科技有限公司 | Pd-l1结合多肽及其用途 |
| KR102396194B1 (ko) * | 2018-12-07 | 2022-05-10 | 서울대학교 산학협력단 | 항 c-Met 아고니스트 항체 및 이의 용도 |
| JP2022535880A (ja) * | 2019-06-06 | 2022-08-10 | アポロミクス インコーポレイテッド（ハンジョウ） | ｃ－ＭＥＴ阻害剤を使用して癌患者を処置するための方法 |
| KR20220063185A (ko) | 2019-09-16 | 2022-05-17 | 리제너론 파마슈티칼스 인코포레이티드 | 면역-pet 영상화를 위한 방사성 표지된 met 결합 단백질 |
| CA3161919A1 (en) | 2020-09-01 | 2022-03-10 | Remegen Co., Ltd. | Anti-c-met antibody-drug conjugate and applications thereof |
| EP4210704A4 (en) * | 2020-09-08 | 2024-08-28 | Ideaya Biosciences, Inc. | PHARMACEUTICAL COMBINATION AND ANTITUMOR TREATMENT |
| AU2023283550A1 (en) * | 2022-06-09 | 2024-11-21 | Santa Ana Bio, Inc. | Antibodies targeting c-kit and/or siglec and uses thereof |
| MA71625A (fr) | 2022-07-30 | 2025-05-30 | Pinetree Therapeutics, Inc. | Compositions pour la dégradation lysosomale ciblée et leurs procédés d'utilisation |
| WO2025036355A1 (zh) * | 2023-08-14 | 2025-02-20 | 明慧医药（杭州）有限公司 | 抗c-MET纳米抗体及其用途 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6214344B1 (en) * | 1995-06-02 | 2001-04-10 | Genetech, Inc. | Hepatocyte growth factor receptor antagonists and uses thereof |
| CA2472383A1 (en) * | 2001-12-27 | 2003-07-17 | Van Andel Research Institute | Monoclonal antibody imaging and therapy of tumors that express met and bind hepatocyte growth factor |
| US20040208876A1 (en) * | 2003-04-18 | 2004-10-21 | Kim Kyung Jin | Monoclonal antibodies to hepatocyte growth factor |
| WO2007056523A2 (en) * | 2005-11-08 | 2007-05-18 | The Government Of The United States Of America As Represented By The Secretary, Department Of Health And Human Services | Methods for diagnosing and monitoring the progression of cancer |
| KR101429297B1 (ko) * | 2006-02-06 | 2014-08-12 | 메테레시스 트랜스레이셔날 리서치 에스.에이. | 종양 치료를 위한 항-Ｍｅｔ 단클론 항체, 이의 단편과벡터 및 상응하는 산물 |
| EP2014681A1 (en) * | 2007-07-12 | 2009-01-14 | Pierre Fabre Medicament | Novel antibodies inhibiting c-met dimerization, and uses thereof |
| US7892770B2 (en) * | 2007-08-24 | 2011-02-22 | Van Andel Research Institute | Monoclonal antibody which binds cMet (HGFR) in formalin-fixed and paraffin-embedded tissues and related methods |
| AR074439A1 (es) * | 2008-12-02 | 2011-01-19 | Pf Medicament | Anticuerpo anti-cmet (receptor c-met) |
| US8545839B2 (en) * | 2008-12-02 | 2013-10-01 | Pierre Fabre Medicament | Anti-c-Met antibody |
| EP2287197A1 (en) * | 2009-08-21 | 2011-02-23 | Pierre Fabre Medicament | Anti-cMET antibody and its use for the detection and the diagnosis of cancer |
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- 2010-08-23 JP JP2012525183A patent/JP5951486B2/ja active Active
- 2010-08-23 AU AU2010284944A patent/AU2010284944B2/en active Active
- 2010-08-23 WO PCT/EP2010/062271 patent/WO2011020925A1/en not_active Ceased
- 2010-08-23 NZ NZ598194A patent/NZ598194A/en unknown
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- 2010-08-23 RU RU2012109004/10A patent/RU2582265C2/ru active
- 2010-08-23 SG SG2012009106A patent/SG178339A1/en unknown
- 2010-08-23 KR KR1020127005757A patent/KR20120051734A/ko not_active Withdrawn
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| EP2467402A1 (en) | 2012-06-27 |
| CN102639564A (zh) | 2012-08-15 |
| IL218202A (en) | 2017-07-31 |
| EP2287197A1 (en) | 2011-02-23 |
| RU2582265C2 (ru) | 2016-04-20 |
| ZA201202076B (en) | 2012-11-28 |
| NZ700437A (en) | 2016-04-29 |
| AU2010284944A1 (en) | 2012-03-08 |
| CA2769427A1 (en) | 2011-02-24 |
| IL218202A0 (en) | 2012-04-30 |
| AR077901A1 (es) | 2011-09-28 |
| NZ598194A (en) | 2015-05-29 |
| US20120149031A1 (en) | 2012-06-14 |
| WO2011020925A1 (en) | 2011-02-24 |
| JP2013502213A (ja) | 2013-01-24 |
| CN102639564B (zh) | 2015-01-07 |
| AU2010284944B2 (en) | 2016-01-28 |
| US8673302B2 (en) | 2014-03-18 |
| KR20120051734A (ko) | 2012-05-22 |
| ES2692522T3 (es) | 2018-12-04 |
| RU2012109004A (ru) | 2013-09-27 |
| EP2467402B1 (en) | 2018-08-01 |
| MX2012002139A (es) | 2012-03-07 |
| BR112012003759A2 (pt) | 2017-07-11 |
| US20140295452A1 (en) | 2014-10-02 |
| JP5951486B2 (ja) | 2016-07-13 |
| SG178339A1 (en) | 2012-03-29 |
| IN2012DN01322A (enExample) | 2015-06-05 |
| CA2769427C (en) | 2020-03-10 |
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