TW201000487A - Hydroxy substituted thieno pyrimidinones as melanin concentrating hormone receptor-1 antagonists - Google Patents
Hydroxy substituted thieno pyrimidinones as melanin concentrating hormone receptor-1 antagonists Download PDFInfo
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- TW201000487A TW201000487A TW098118073A TW98118073A TW201000487A TW 201000487 A TW201000487 A TW 201000487A TW 098118073 A TW098118073 A TW 098118073A TW 98118073 A TW98118073 A TW 98118073A TW 201000487 A TW201000487 A TW 201000487A
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- 125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
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- 150000003509 tertiary alcohols Chemical class 0.000 description 1
- 229950004704 tesaglitazar Drugs 0.000 description 1
- DAZSLCYGSKMFLB-UHFFFAOYSA-B tetrabismuth;phosphonato phosphate Chemical compound [Bi+3].[Bi+3].[Bi+3].[Bi+3].[O-]P([O-])(=O)OP([O-])([O-])=O.[O-]P([O-])(=O)OP([O-])([O-])=O.[O-]P([O-])(=O)OP([O-])([O-])=O DAZSLCYGSKMFLB-UHFFFAOYSA-B 0.000 description 1
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Classifications
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- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
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- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
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- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
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- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
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- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
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- Psychiatry (AREA)
- Emergency Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
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| US12/473,346 US7989433B2 (en) | 2008-05-29 | 2009-05-28 | Substituted thieno[3,2-D]pyrimidines as melanin concentrating hormone receptor-1 antagonists |
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| TW098118073A TW201000487A (en) | 2008-05-29 | 2009-06-01 | Hydroxy substituted thieno pyrimidinones as melanin concentrating hormone receptor-1 antagonists |
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| JP (1) | JP2011521962A (enExample) |
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| AU (1) | AU2009251331A1 (enExample) |
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| EA (1) | EA201001882A1 (enExample) |
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| MX (1) | MX2010012803A (enExample) |
| PE (1) | PE20091928A1 (enExample) |
| TW (1) | TW201000487A (enExample) |
| WO (1) | WO2009146365A1 (enExample) |
| ZA (1) | ZA201008451B (enExample) |
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| JP2010525077A (ja) * | 2007-04-25 | 2010-07-22 | ブリストル−マイヤーズ スクイブ カンパニー | 非塩基性メラニン凝集ホルモン受容体−１アンタゴニスト |
| CA2790284C (en) | 2010-02-17 | 2019-01-08 | Takeda Pharmaceutical Company Limited | Thieno-pyrimidine compounds having cdc7 inhibitory activity |
| CN103957998B (zh) | 2011-12-06 | 2018-06-12 | 荷兰联合利华有限公司 | 皮肤抗老化组合物 |
| IL225900A0 (en) * | 2013-04-22 | 2014-03-31 | Perrigo Api Ltd | A process for the preparation of nicotine that includes the enzymatic reduction of 4-(methylamino)-1-(3-pyridinyl)-1-butanone |
| EP2921856B1 (en) * | 2014-03-18 | 2016-09-14 | Serum Institute Of India Private Limited | A quantitative assay for 4-pyrrolidinopyridine (4-ppy) in polysaccharide-protein conjugate vaccines |
| US20170290333A1 (en) | 2014-12-30 | 2017-10-12 | Dow Agrosciences Llc | Picolinamide compounds with fungicidal activity |
| EP3240412A4 (en) * | 2014-12-30 | 2018-04-25 | Dow Agrosciences LLC | Use of picolinamide compounds with fungicidal activity |
| CN115350184A (zh) * | 2020-01-10 | 2022-11-18 | 康圣博施医药有限公司 | 药物的治疗组合以及其使用方法 |
| HUP2200222A1 (hu) | 2022-06-17 | 2023-12-28 | Richter Gedeon Nyrt | MCHR1 antagonisták a Prader-Willi szindróma kezelésére |
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| US3674836A (en) * | 1968-05-21 | 1972-07-04 | Parke Davis & Co | 2,2-dimethyl-{11 -aryloxy-alkanoic acids and salts and esters thereof |
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| JPS5612114B2 (enExample) * | 1974-06-07 | 1981-03-18 | ||
| JPS5432794A (en) | 1977-08-18 | 1979-03-10 | Omron Tateisi Electronics Co | Manufacturing method of terminal rack |
| NO154918C (no) * | 1977-08-27 | 1987-01-14 | Bayer Ag | Analogifremgangsmaate til fremstilling av terapeutisk aktive derivater av 3,4,5-trihydroksypiperidin. |
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-
2009
- 2009-05-27 PE PE2009000744A patent/PE20091928A1/es not_active Application Discontinuation
- 2009-05-28 US US12/473,346 patent/US7989433B2/en active Active
- 2009-05-28 MX MX2010012803A patent/MX2010012803A/es not_active Application Discontinuation
- 2009-05-28 AR ARP090101925A patent/AR075260A1/es unknown
- 2009-05-28 WO PCT/US2009/045452 patent/WO2009146365A1/en not_active Ceased
- 2009-05-28 KR KR1020107029384A patent/KR20110021988A/ko not_active Withdrawn
- 2009-05-28 EP EP09755726A patent/EP2310394A1/en not_active Withdrawn
- 2009-05-28 JP JP2011511814A patent/JP2011521962A/ja not_active Withdrawn
- 2009-05-28 CN CN2009801280666A patent/CN102099360A/zh active Pending
- 2009-05-28 AU AU2009251331A patent/AU2009251331A1/en not_active Abandoned
- 2009-05-28 EA EA201001882A patent/EA201001882A1/ru unknown
- 2009-05-28 BR BRPI0913197A patent/BRPI0913197A2/pt not_active Application Discontinuation
- 2009-05-28 CA CA2726264A patent/CA2726264A1/en not_active Abandoned
- 2009-06-01 TW TW098118073A patent/TW201000487A/zh unknown
-
2010
- 2010-11-16 IL IL209354A patent/IL209354A0/en unknown
- 2010-11-24 ZA ZA2010/08451A patent/ZA201008451B/en unknown
- 2010-11-30 CO CO10151012A patent/CO6280492A2/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP2310394A1 (en) | 2011-04-20 |
| JP2011521962A (ja) | 2011-07-28 |
| BRPI0913197A2 (pt) | 2016-01-12 |
| AU2009251331A1 (en) | 2009-12-03 |
| MX2010012803A (es) | 2010-12-07 |
| US7989433B2 (en) | 2011-08-02 |
| EA201001882A1 (ru) | 2011-06-30 |
| IL209354A0 (en) | 2011-01-31 |
| ZA201008451B (en) | 2012-04-25 |
| CN102099360A (zh) | 2011-06-15 |
| CA2726264A1 (en) | 2009-12-03 |
| KR20110021988A (ko) | 2011-03-04 |
| US20090298794A1 (en) | 2009-12-03 |
| CO6280492A2 (es) | 2011-05-20 |
| PE20091928A1 (es) | 2009-12-31 |
| WO2009146365A1 (en) | 2009-12-03 |
| AR075260A1 (es) | 2011-03-23 |
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