JP2011521962A - メラニン凝集ホルモン受容体−１アンタゴニストとしてのヒドロキシ置換チエノピリミジノン - Google Patents

メラニン凝集ホルモン受容体−１アンタゴニストとしてのヒドロキシ置換チエノピリミジノン Download PDF

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Publication number
JP2011521962A
JP2011521962A JP2011511814A JP2011511814A JP2011521962A JP 2011521962 A JP2011521962 A JP 2011521962A JP 2011511814 A JP2011511814 A JP 2011511814A JP 2011511814 A JP2011511814 A JP 2011511814A JP 2011521962 A JP2011521962 A JP 2011521962A
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compound
prodrug
mmol
agent
alkyl
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Japanese (ja)
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JP2011521962A5 (enExample
Inventor
ウィリアム・エヌ・ウォッシュバーン
サリーム・アフマド
プラティック・デバスセイル
ジェフリー・エイ・ロブル
アニメシュ・ゴズワミ
ジウェイ・グオ
ラメシュ・エヌ・ペイテル
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Bristol Myers Squibb Co
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Bristol Myers Squibb Co
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Publication of JP2011521962A publication Critical patent/JP2011521962A/ja
Publication of JP2011521962A5 publication Critical patent/JP2011521962A5/ja
Withdrawn legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Neurosurgery (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Endocrinology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Psychiatry (AREA)
  • Rheumatology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
JP2011511814A 2008-05-29 2009-05-28 メラニン凝集ホルモン受容体−１アンタゴニストとしてのヒドロキシ置換チエノピリミジノン Withdrawn JP2011521962A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US5694908P 2008-05-29 2008-05-29
US61/056,949 2008-05-29
PCT/US2009/045452 WO2009146365A1 (en) 2008-05-29 2009-05-28 Hydroxy substituted thieno pyrimidinones as melanin concentrating hormone receptor-1 antagonists

Publications (2)

Publication Number Publication Date
JP2011521962A true JP2011521962A (ja) 2011-07-28
JP2011521962A5 JP2011521962A5 (enExample) 2011-10-06

Family

ID=41017166

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2011511814A Withdrawn JP2011521962A (ja) 2008-05-29 2009-05-28 メラニン凝集ホルモン受容体−１アンタゴニストとしてのヒドロキシ置換チエノピリミジノン

Country Status (17)

Country Link
US (1) US7989433B2 (enExample)
EP (1) EP2310394A1 (enExample)
JP (1) JP2011521962A (enExample)
KR (1) KR20110021988A (enExample)
CN (1) CN102099360A (enExample)
AR (1) AR075260A1 (enExample)
AU (1) AU2009251331A1 (enExample)
BR (1) BRPI0913197A2 (enExample)
CA (1) CA2726264A1 (enExample)
CO (1) CO6280492A2 (enExample)
EA (1) EA201001882A1 (enExample)
IL (1) IL209354A0 (enExample)
MX (1) MX2010012803A (enExample)
PE (1) PE20091928A1 (enExample)
TW (1) TW201000487A (enExample)
WO (1) WO2009146365A1 (enExample)
ZA (1) ZA201008451B (enExample)

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* Cited by examiner, † Cited by third party
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WO2008134480A1 (en) * 2007-04-25 2008-11-06 Bristol-Myers Squibb Company Non-basic melanin concentrating hormone receptor-1 antagonists
US8722660B2 (en) 2010-02-17 2014-05-13 Takeda Pharmaceutical Company Limited Heterocyclic compound
EP2788088B1 (en) 2011-12-06 2019-06-19 Unilever Plc. Skin anti-ageing composition
IL225900A0 (en) * 2013-04-22 2014-03-31 Perrigo Api Ltd A process for the preparation of nicotine that includes the enzymatic reduction of 4-(methylamino)-1-(3-pyridinyl)-1-butanone
EP2921856B1 (en) * 2014-03-18 2016-09-14 Serum Institute Of India Private Limited A quantitative assay for 4-pyrrolidinopyridine (4-ppy) in polysaccharide-protein conjugate vaccines
BR112017013758B1 (pt) * 2014-12-30 2021-11-23 Dow Agrosciences Llc Compostos de picolinamida com atividade fungicida
CA2972401C (en) 2014-12-30 2023-09-05 Dow Agrosciences Llc Picolinamide compounds with fungicidal activity
EP4151210A3 (en) * 2020-01-10 2023-06-14 Harmony Biosciences, LLC Pyridine-carboline derivatives as mchr1 antagonists for use in therapy
HUP2200222A1 (hu) 2022-06-17 2023-12-28 Richter Gedeon Nyrt MCHR1 antagonisták a Prader-Willi szindróma kezelésére

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Also Published As

Publication number Publication date
AR075260A1 (es) 2011-03-23
AU2009251331A1 (en) 2009-12-03
IL209354A0 (en) 2011-01-31
EA201001882A1 (ru) 2011-06-30
CO6280492A2 (es) 2011-05-20
US20090298794A1 (en) 2009-12-03
BRPI0913197A2 (pt) 2016-01-12
WO2009146365A1 (en) 2009-12-03
ZA201008451B (en) 2012-04-25
CA2726264A1 (en) 2009-12-03
US7989433B2 (en) 2011-08-02
MX2010012803A (es) 2010-12-07
PE20091928A1 (es) 2009-12-31
CN102099360A (zh) 2011-06-15
KR20110021988A (ko) 2011-03-04
EP2310394A1 (en) 2011-04-20
TW201000487A (en) 2010-01-01

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