ZA201008451B - Hydroxy substituted thieno pyrimidinones as melanin concentrating hormone receptor-1 antagonists - Google Patents

Hydroxy substituted thieno pyrimidinones as melanin concentrating hormone receptor-1 antagonists

Info

Publication number
ZA201008451B
ZA201008451B ZA2010/08451A ZA201008451A ZA201008451B ZA 201008451 B ZA201008451 B ZA 201008451B ZA 2010/08451 A ZA2010/08451 A ZA 2010/08451A ZA 201008451 A ZA201008451 A ZA 201008451A ZA 201008451 B ZA201008451 B ZA 201008451B
Authority
ZA
South Africa
Prior art keywords
pyrimidinones
antagonists
hormone receptor
hydroxy substituted
concentrating hormone
Prior art date
Application number
ZA2010/08451A
Other languages
English (en)
Inventor
William N Washburn
Saleem Ahmad
Pratik Devasthale
Jeffrey A Robl
Animesh Goswami
Zhiheng Guo
Ramesh N Patel
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of ZA201008451B publication Critical patent/ZA201008451B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Neurology (AREA)
  • Hematology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Rheumatology (AREA)
  • Psychiatry (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
ZA2010/08451A 2008-05-29 2010-11-24 Hydroxy substituted thieno pyrimidinones as melanin concentrating hormone receptor-1 antagonists ZA201008451B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5694908P 2008-05-29 2008-05-29
PCT/US2009/045452 WO2009146365A1 (en) 2008-05-29 2009-05-28 Hydroxy substituted thieno pyrimidinones as melanin concentrating hormone receptor-1 antagonists

Publications (1)

Publication Number Publication Date
ZA201008451B true ZA201008451B (en) 2012-04-25

Family

ID=41017166

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA2010/08451A ZA201008451B (en) 2008-05-29 2010-11-24 Hydroxy substituted thieno pyrimidinones as melanin concentrating hormone receptor-1 antagonists

Country Status (17)

Country Link
US (1) US7989433B2 (enExample)
EP (1) EP2310394A1 (enExample)
JP (1) JP2011521962A (enExample)
KR (1) KR20110021988A (enExample)
CN (1) CN102099360A (enExample)
AR (1) AR075260A1 (enExample)
AU (1) AU2009251331A1 (enExample)
BR (1) BRPI0913197A2 (enExample)
CA (1) CA2726264A1 (enExample)
CO (1) CO6280492A2 (enExample)
EA (1) EA201001882A1 (enExample)
IL (1) IL209354A0 (enExample)
MX (1) MX2010012803A (enExample)
PE (1) PE20091928A1 (enExample)
TW (1) TW201000487A (enExample)
WO (1) WO2009146365A1 (enExample)
ZA (1) ZA201008451B (enExample)

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JP2010525077A (ja) * 2007-04-25 2010-07-22 ブリストル−マイヤーズ スクイブ カンパニー 非塩基性メラニン凝集ホルモン受容体−１アンタゴニスト
MX353500B (es) 2010-02-17 2018-01-16 Takeda Pharmaceuticals Co Compuesto heterociclico.
WO2013083431A1 (en) 2011-12-06 2013-06-13 Unilever Plc Skin anti-ageing composition
IL225900A0 (en) * 2013-04-22 2014-03-31 Perrigo Api Ltd A process for the preparation of nicotine that includes the enzymatic reduction of 4-(methylamino)-1-(3-pyridinyl)-1-butanone
EP2921856B1 (en) * 2014-03-18 2016-09-14 Serum Institute Of India Private Limited A quantitative assay for 4-pyrrolidinopyridine (4-ppy) in polysaccharide-protein conjugate vaccines
EP3240413B1 (en) * 2014-12-30 2020-05-13 Dow Agrosciences LLC Picolinamide compounds with fungicidal activity
RU2708392C2 (ru) 2014-12-30 2019-12-06 ДАУ АГРОСАЙЕНСИЗ ЭлЭлСи Соединения пиколинамида с фунгицидной активностью
WO2021142395A1 (en) * 2020-01-10 2021-07-15 Consynance Therapeutics, Inc. Therapeutic combinations of drugs and methods of using them
HUP2200222A1 (hu) 2022-06-17 2023-12-28 Richter Gedeon Nyrt MCHR1 antagonisták a Prader-Willi szindróma kezelésére

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Also Published As

Publication number Publication date
TW201000487A (en) 2010-01-01
IL209354A0 (en) 2011-01-31
JP2011521962A (ja) 2011-07-28
AU2009251331A1 (en) 2009-12-03
CO6280492A2 (es) 2011-05-20
EA201001882A1 (ru) 2011-06-30
EP2310394A1 (en) 2011-04-20
AR075260A1 (es) 2011-03-23
MX2010012803A (es) 2010-12-07
US20090298794A1 (en) 2009-12-03
BRPI0913197A2 (pt) 2016-01-12
PE20091928A1 (es) 2009-12-31
WO2009146365A1 (en) 2009-12-03
CN102099360A (zh) 2011-06-15
CA2726264A1 (en) 2009-12-03
KR20110021988A (ko) 2011-03-04
US7989433B2 (en) 2011-08-02

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