TW200934784A - Therapeutic cancer treatments - Google Patents
Therapeutic cancer treatments Download PDFInfo
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- TW200934784A TW200934784A TW097151085A TW97151085A TW200934784A TW 200934784 A TW200934784 A TW 200934784A TW 097151085 A TW097151085 A TW 097151085A TW 97151085 A TW97151085 A TW 97151085A TW 200934784 A TW200934784 A TW 200934784A
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- cancer
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- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
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- A61K33/243—Platinum; Compounds thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- Health & Medical Sciences (AREA)
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Steroid Compounds (AREA)
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| TWI433674B (zh) | 2006-12-28 | 2014-04-11 | Infinity Discovery Inc | 環杷明（ｃｙｃｌｏｐａｍｉｎｅ）類似物類 |
| ES2610130T3 (es) | 2007-12-27 | 2017-04-26 | Infinity Pharmaceuticals, Inc. | Métodos para reducción estereoselectiva |
| US20100297118A1 (en) * | 2007-12-27 | 2010-11-25 | Macdougall John | Therapeutic Cancer Treatments |
| JP2012515792A (ja) * | 2009-01-23 | 2012-07-12 | キャンサー・リサーチ・テクノロジー・リミテッド | ヘッジホッグ経路阻害剤 |
| EP2462115B1 (en) | 2009-08-05 | 2016-01-06 | Infinity Pharmaceuticals, Inc. | Enzymatic transamination of cyclopamine analogs |
| KR20120053052A (ko) * | 2009-08-25 | 2012-05-24 | 아브락시스 바이오사이언스, 엘엘씨 | 헤지호그 억제제 및 탁산의 나노입자 조성물로의 조합 요법 |
| WO2011088404A1 (en) * | 2010-01-15 | 2011-07-21 | Infinity Pharmaceuticals , Inc | Treatment of fibrotic conditions using hedgehog inhibitors |
| US20120010230A1 (en) * | 2010-07-08 | 2012-01-12 | Macdougall John R | Methods and compositions for identification, assessment and treatment of cancers associated with hedgehog signaling |
| US20120010229A1 (en) * | 2010-07-08 | 2012-01-12 | Macdougall John R | Therapeutic regimens for hedgehog-associated cancers |
| US9394313B2 (en) | 2010-09-14 | 2016-07-19 | Infinity Pharmaceuticals, Inc. | Transfer hydrogenation of cyclopamine analogs |
| RU2492855C2 (ru) * | 2011-02-15 | 2013-09-20 | Федеральное государственное бюджетное учреждение "Научно-исследовательский институт онкологии" СО РАМН (ФГБУ "НИИ онкологии" СО РАМН) | Способ комбинированного лечения немелкоклеточного рака легкого ii и iii стадии с пред- и послеоперационной химиотерапией |
| CA2752008A1 (en) | 2011-09-13 | 2013-03-13 | Universite De Montreal | Combination therapy using ribavirin as elf4e inhibitor |
| BR112017000800A8 (pt) * | 2014-07-17 | 2023-04-25 | Biocurity Holdings Inc | Tratamento do câncer com uma combinação de radiação, nanoparticulas de óxido de cério, e um agente quimioterápico |
| JP6815331B2 (ja) * | 2015-04-21 | 2021-01-20 | ジェネンテック， インコーポレイテッド | 前立腺がんの分析のための組成物及び方法 |
| CA2988289C (en) | 2015-06-04 | 2023-12-05 | PellePharm, Inc. | Topical formulations for delivery of hedgehog inhibitor compounds and use thereof |
| CN107137406B (zh) * | 2016-03-01 | 2021-07-02 | 江苏恒瑞医药股份有限公司 | 一种Hedgehog信号通路抑制剂在制备治疗EGFR过度表达的癌症的药物中的用途 |
| ES2972741T3 (es) * | 2016-08-10 | 2024-06-14 | Celgene Quanticel Res Inc | Tratamiento del carcinoma de células de Merkel |
| KR102667951B1 (ko) | 2017-04-03 | 2024-05-22 | 에프. 호프만-라 로슈 아게 | Steap-1에 결합하는 항체 |
| CN110776507B (zh) * | 2018-07-31 | 2020-12-18 | 苏州亚盛药业有限公司 | Bcl-2抑制剂与化疗药的组合产品及其在预防和/或治疗疾病中的用途 |
| BR112020018978A2 (pt) | 2018-07-31 | 2021-03-02 | Ascentage Pharma (Suzhou) Co., Ltd. | produto de combinação que compreende um inibidor de bcl-2 e um inibidor de mdm2 e uso dos ditos inibidores na prevenção e/ou tratamento de câncer |
| CN114522167A (zh) | 2018-07-31 | 2022-05-24 | 苏州亚盛药业有限公司 | Bcl-2抑制剂或Bcl-2/Bcl-xL抑制剂与BTK抑制剂的组合产品及其用途 |
| EP3672591B1 (en) | 2018-07-31 | 2024-02-14 | Ascentage Pharma (Suzhou) Co., Ltd. | Synergistic antitumor effect of bcl-2 inhibitor combined with rituximab and/or bendamustine or bcl-2 inhibitor combined with chop |
| CN115282133A (zh) * | 2021-12-06 | 2022-11-04 | 温州医科大学 | 竹红菌乙素在制备抗结肠癌药物中的应用 |
| KR20250130413A (ko) * | 2023-01-12 | 2025-09-01 | 솔-겔 테크놀로지스 리미티드 | 파티데깁을 포함하는 국소 조성물을 이용한 기저 세포 암종의 치료 및 예방 |
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| US7709454B2 (en) * | 1997-06-20 | 2010-05-04 | New York University | Methods and compositions for inhibiting tumorigenesis |
| US6238876B1 (en) * | 1997-06-20 | 2001-05-29 | New York University | Methods and materials for the diagnosis and treatment of sporadic basal cell carcinoma |
| US7741298B2 (en) * | 1997-06-20 | 2010-06-22 | New York University | Method and compositions for inhibiting tumorigenesis |
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| US7291626B1 (en) * | 1998-04-09 | 2007-11-06 | John Hopkins University School Of Medicine | Inhibitors of hedgehog signaling pathways, compositions and uses related thereto |
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| CA2339330A1 (en) * | 1998-08-13 | 2000-02-24 | University Of Southern California | Methods to increase blood flow to ischemic tissue |
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| US20060252073A1 (en) * | 2005-04-18 | 2006-11-09 | Regents Of The University Of Michigan | Compositions and methods for the treatment of cancer |
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| US20100222287A1 (en) * | 2007-12-27 | 2010-09-02 | Mcgovern Karen J | Therapeutic Cancer Treatments |
| US20100297118A1 (en) * | 2007-12-27 | 2010-11-25 | Macdougall John | Therapeutic Cancer Treatments |
| CL2009001479A1 (es) * | 2008-07-02 | 2010-01-04 | Infinity Pharmaceuticals Inc | Metodo para aislar un alcaloide del veratrum desglicosilado que comprende proporcionar un material de planta veratrum, poner en contacto con una solucion acuosa y extraer el material de la planta veratrum con un solvente para proporcionar un extracto que comprende dicho alcaloide. |
| WO2011088404A1 (en) * | 2010-01-15 | 2011-07-21 | Infinity Pharmaceuticals , Inc | Treatment of fibrotic conditions using hedgehog inhibitors |
| US20120010230A1 (en) * | 2010-07-08 | 2012-01-12 | Macdougall John R | Methods and compositions for identification, assessment and treatment of cancers associated with hedgehog signaling |
| US20120010229A1 (en) * | 2010-07-08 | 2012-01-12 | Macdougall John R | Therapeutic regimens for hedgehog-associated cancers |
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| AU2008345151A1 (en) | 2009-07-09 |
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| BRPI0821779A2 (pt) | 2019-09-24 |
| AR070047A1 (es) | 2010-03-10 |
| EP2225254A4 (en) | 2011-03-30 |
| JP2011522773A (ja) | 2011-08-04 |
| CL2008003901A1 (es) | 2009-07-24 |
| WO2009086416A1 (en) | 2009-07-09 |
| EP2225254A1 (en) | 2010-09-08 |
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