TW200813095A - N-terminally modified GLP-1 receptor modulators - Google Patents
N-terminally modified GLP-1 receptor modulators Download PDFInfo
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- TW200813095A TW200813095A TW096118798A TW96118798A TW200813095A TW 200813095 A TW200813095 A TW 200813095A TW 096118798 A TW096118798 A TW 096118798A TW 96118798 A TW96118798 A TW 96118798A TW 200813095 A TW200813095 A TW 200813095A
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- 108010086246 Glucagon-Like Peptide-1 Receptor Proteins 0.000 title claims abstract description 7
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- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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Landscapes
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| EP2021014A1 (en) | 2006-05-26 | 2009-02-11 | Brystol-Myers Squibb Company | Sustained release glp-1 receptor modulators |
| JO2945B1 (en) | 2006-09-13 | 2016-03-15 | سميث كلاين بيتشام كوربوريشن | Methods of giving prolonged hypoglycemic agents |
| CA2707448C (en) * | 2007-12-11 | 2014-10-14 | Cadila Healthcare Limited | Peptidomimetics with glucagon antagonistic and glp-1 agonistic activities |
| SMT201700189T1 (it) | 2008-12-10 | 2017-05-08 | Glaxosmithkline Llc | Composizioni farmaceutiche di albiglutide |
| JP2012528847A (ja) * | 2009-06-05 | 2012-11-15 | ファイザー・インク | Ｇｐｒ１１９調節因子としてのｌ−（ピペリジン−４−イル）−ピラゾール誘導体 |
| WO2011063414A1 (en) | 2009-11-23 | 2011-05-26 | Amylin Pharmaceuticals, Inc. | Polypeptide conjugate |
| WO2011140176A1 (en) | 2010-05-04 | 2011-11-10 | Glaxosmithkline Llc | Methods for treating or preventing cardiovascular disorders and providing cardiovascular protection |
| EA024507B1 (ru) | 2010-09-28 | 2016-09-30 | Амилин Фармасьютикалс, Ллк | Хорошо растворимые лептины |
| EP3028720A1 (en) | 2010-09-28 | 2016-06-08 | Amylin Pharmaceuticals, LLC | Engineered polypeptides having enhanced duration of action |
| MX347014B (es) * | 2010-11-24 | 2017-04-07 | Durect Corp | Composición para administración de fármaco biodegradable. |
| WO2012098188A1 (en) * | 2011-01-19 | 2012-07-26 | Novo Nordisk A/S | Glp-1 particles and compositions |
| EP2714069A4 (en) | 2011-05-25 | 2015-06-24 | Amylin Pharmaceuticals Llc | LONG-TERM CONJUGATES WITH TWO HORMONES |
| DK2729160T3 (da) | 2011-07-08 | 2019-07-01 | Aegerion Pharmaceuticals Inc | Manipulerede polypeptider, der har forbedret virkningstid og reduceret immunogenicitet |
| CN104271588B (zh) | 2011-07-08 | 2017-10-10 | 安米林药品有限责任公司 | 具有增强的作用持续时间和降低的免疫原性的工程改造的多肽 |
| DK2776055T3 (en) * | 2011-08-17 | 2017-03-06 | Ironwood Pharmaceuticals Inc | TREATMENTS FOR GASTROINTESTINAL DISORDERS |
| CN102363633B (zh) * | 2011-11-16 | 2013-11-20 | 天津拓飞生物科技有限公司 | 胰高血糖素样肽-1突变体多肽及其制备方法、药物组合物和其应用 |
| ES2663869T3 (es) * | 2011-12-23 | 2018-04-17 | Ipsen Manufacturing Ireland Limited | Procedimiento para la síntesis de análogos de la grelina |
| KR20150093647A (ko) * | 2012-07-06 | 2015-08-18 | 블루 워터 테크놀로지스, 인크. | 회전 벨트 스크린 및 필터를 위한 운동량이 향상된 클리닝 장치 |
| UA116217C2 (uk) | 2012-10-09 | 2018-02-26 | Санофі | Пептидна сполука як подвійний агоніст рецепторів glp1-1 та глюкагону |
| PT2934568T (pt) | 2012-12-21 | 2018-01-04 | Sanofi Sa | Agonistas duplos de glp1/gip ou trigonais de glp1/gip/glucagina |
| SG11201506885UA (en) | 2013-03-21 | 2015-09-29 | Sanofi Aventis Deutschland | Synthesis of cyclic imide containing peptide products |
| HK1219477A1 (zh) | 2013-03-21 | 2017-04-07 | Sanofi-Aventis Deutschland Gmbh | 合成含有乙内酰脲的肽产物 |
| CN104548096B (zh) * | 2013-10-09 | 2019-09-10 | 深圳翰宇药业股份有限公司 | 一种含有glp-1类似物和dpp-4抑制剂的药物组合物及其制备方法 |
| CN105764491A (zh) | 2013-12-09 | 2016-07-13 | 度瑞公司 | 药物活性剂复合物、聚合物复合物，以及包括其的组合物和方法 |
| TW201609796A (zh) | 2013-12-13 | 2016-03-16 | 賽諾菲公司 | 非醯化之艾塞那肽－４（ｅｘｅｎｄｉｎ－４）胜肽類似物 |
| TW201609797A (zh) | 2013-12-13 | 2016-03-16 | 賽諾菲公司 | 雙重ｇｌｐ－１／升糖素受體促效劑 |
| TW201609799A (zh) | 2013-12-13 | 2016-03-16 | 賽諾菲公司 | 雙重ｇｌｐ－１／ｇｉｐ受體促效劑 |
| TW201609795A (zh) | 2013-12-13 | 2016-03-16 | 賽諾菲公司 | 作為雙重ｇｌｐ－１／ｇｉｐ受體促效劑的艾塞那肽－４（ｅｘｅｎｄｉｎ－４）胜肽類似物 |
| SG10201805039UA (en) * | 2013-12-13 | 2018-07-30 | Medimmune Ltd | Protease resistant peptides |
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-
2006
- 2006-11-08 EP EP06839759A patent/EP2021014A1/en not_active Withdrawn
- 2006-11-08 WO PCT/US2006/060644 patent/WO2007139589A1/en not_active Ceased
- 2006-11-08 US US12/227,780 patent/US20100022457A1/en not_active Abandoned
-
2007
- 2007-05-25 TW TW096118798A patent/TW200813095A/zh unknown
- 2007-05-25 JP JP2009513397A patent/JP2009538360A/ja active Pending
- 2007-05-25 US US11/753,616 patent/US7960349B2/en active Active
- 2007-05-25 CN CNA2007800281605A patent/CN101495502A/zh active Pending
- 2007-05-25 EP EP07797751A patent/EP2021354A2/en not_active Withdrawn
- 2007-05-25 PE PE2007000653A patent/PE20080709A1/es not_active Application Discontinuation
- 2007-05-25 WO PCT/US2007/069703 patent/WO2007140284A2/en not_active Ceased
- 2007-05-28 AR ARP070102288A patent/AR061203A1/es unknown
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| WO2007140284A2 (en) | 2007-12-06 |
| EP2021014A1 (en) | 2009-02-11 |
| US20080045461A1 (en) | 2008-02-21 |
| PE20080709A1 (es) | 2008-06-14 |
| US7960349B2 (en) | 2011-06-14 |
| WO2007140284A4 (en) | 2009-03-05 |
| CN101495502A (zh) | 2009-07-29 |
| WO2007139589A1 (en) | 2007-12-06 |
| US20100022457A1 (en) | 2010-01-28 |
| JP2009538360A (ja) | 2009-11-05 |
| AR061203A1 (es) | 2008-08-13 |
| WO2007140284A3 (en) | 2008-12-31 |
| EP2021354A2 (en) | 2009-02-11 |
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