TW200744623A - Compositions and methods for eliciting an immune response to escape mutants of targeted therapies - Google Patents

Compositions and methods for eliciting an immune response to escape mutants of targeted therapies

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Publication number
TW200744623A
TW200744623A TW095125273A TW95125273A TW200744623A TW 200744623 A TW200744623 A TW 200744623A TW 095125273 A TW095125273 A TW 095125273A TW 95125273 A TW95125273 A TW 95125273A TW 200744623 A TW200744623 A TW 200744623A
Authority
TW
Taiwan
Prior art keywords
immune response
eliciting
compositions
methods
targeted therapies
Prior art date
Application number
TW095125273A
Other languages
English (en)
Inventor
David Apelian
Alex Franzusoff
Timothy C Rodell
Original Assignee
Globeimmune Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Globeimmune Inc filed Critical Globeimmune Inc
Publication of TW200744623A publication Critical patent/TW200744623A/zh

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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
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    • A—HUMAN NECESSITIES
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    • A61K2039/523—Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
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    • C12N2730/00—Reverse transcribing DNA viruses
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    • C12N2730/10011—Hepadnaviridae
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    • C12N2730/00—Reverse transcribing DNA viruses
    • C12N2730/00011—Details
    • C12N2730/10011—Hepadnaviridae
    • C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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    • C12N2740/00—Reverse transcribing RNA viruses
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    • C12N2740/16011—Human Immunodeficiency Virus, HIV
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    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16211—Human Immunodeficiency Virus, HIV concerning HIV gagpol
    • C12N2740/16234—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
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    • C12N2770/24011—Flaviviridae
    • C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
    • C12N2770/24234—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

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  • Health & Medical Sciences (AREA)
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  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Genetics & Genomics (AREA)
  • Communicable Diseases (AREA)
  • Organic Chemistry (AREA)
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  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Gynecology & Obstetrics (AREA)
  • Vascular Medicine (AREA)
  • Reproductive Health (AREA)
  • Pregnancy & Childbirth (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
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  • Biochemistry (AREA)
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  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Hematology (AREA)
TW095125273A 2005-07-11 2006-07-11 Compositions and methods for eliciting an immune response to escape mutants of targeted therapies TW200744623A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US69838105P 2005-07-11 2005-07-11

Publications (1)

Publication Number Publication Date
TW200744623A true TW200744623A (en) 2007-12-16

Family

ID=37568336

Family Applications (1)

Application Number Title Priority Date Filing Date
TW095125273A TW200744623A (en) 2005-07-11 2006-07-11 Compositions and methods for eliciting an immune response to escape mutants of targeted therapies

Country Status (12)

Country Link
US (2) US20100034840A1 (zh)
EP (2) EP2371381A3 (zh)
JP (1) JP2009500454A (zh)
KR (1) KR20080043775A (zh)
CN (1) CN101262883A (zh)
AU (1) AU2006268333B2 (zh)
BR (1) BRPI0613025A2 (zh)
CA (1) CA2614884A1 (zh)
IL (1) IL188717A0 (zh)
SG (1) SG163572A1 (zh)
TW (1) TW200744623A (zh)
WO (1) WO2007008780A2 (zh)

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TW200806789A (en) * 2006-03-27 2008-02-01 Globeimmune Inc RAS mutation and compositions and methods related thereto
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TWI478720B (zh) * 2007-03-20 2015-04-01 Globeimmune Inc 對癌症標的療法之脫逃突變種誘發免疫反應之組合物與方法
ES2725450T3 (es) 2007-07-02 2019-09-24 Etubics Corp Métodos y composiciones para la producción de un vector adenoviral para su uso en vacunaciones múltiples
WO2009046738A1 (en) * 2007-10-09 2009-04-16 Curevac Gmbh Composition for treating lung cancer, particularly of non-small lung cancers (nsclc)
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JP5759980B2 (ja) 2009-04-17 2015-08-05 グローブイミューン，インコーポレイテッド 癌および感染症に対する免疫療法組成物の組み合わせ
EP2477647B1 (en) 2009-09-14 2016-01-13 The Regents of the University of Colorado Modulation of yeast-based immunotherapy products and responses
JP2013522302A (ja) * 2010-03-14 2013-06-13 グローブイミューン，インコーポレイテッド 酵母系免疫療法を使用した感染症の薬理ゲノミクス及び治療反応性ガイド治療
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ES2696551T3 (es) 2010-12-17 2019-01-16 Globeimmune Inc Composiciones y métodos para el tratamiento o la prevención de la infección por adenovirus-36 humano
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SG163572A1 (en) 2010-08-30
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WO2007008780A3 (en) 2007-03-22
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CA2614884A1 (en) 2007-01-18
EP1906997A2 (en) 2008-04-09
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