TW200409645A

TW200409645A - Stable liquid parenteral PARECOXIB formulation

Stable liquid parenteral PARECOXIB formulation Download PDF

Info

Publication number: TW200409645A
Authority: TW; Taiwan
Prior art keywords: parecoxib; composition; salt; solvent; patent application
Prior art date: 2002-06-26

Application number

TW092117433A

Other languages

English (en)

Chinese (zh)

Inventor

Yatin R Gokarn

Richard Schartman

Original Assignee

Pharmacia Corp

Priority date

2002-06-26

Filing date

2003-06-26

Publication date

2004-06-16

2003-06-26 Application filed by Pharmacia Corp filed Critical Pharmacia Corp

2004-06-16 Publication of TW200409645A publication Critical patent/TW200409645A/zh

Links

239000000203 mixture Substances 0.000 title claims abstract description 215
TZRHLKRLEZJVIJ-UHFFFAOYSA-N parecoxib Chemical compound C1=CC(S(=O)(=O)NC(=O)CC)=CC=C1C1=C(C)ON=C1C1=CC=CC=C1 TZRHLKRLEZJVIJ-UHFFFAOYSA-N 0.000 title claims abstract description 145
229960004662 parecoxib Drugs 0.000 title claims abstract description 104
239000007788 liquid Substances 0.000 title claims abstract description 79
238000009472 formulation Methods 0.000 title description 45
239000002904 solvent Substances 0.000 claims abstract description 80
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239000002253 acid Substances 0.000 claims abstract description 40
238000006243 chemical reaction Methods 0.000 claims abstract description 17
238000007911 parenteral administration Methods 0.000 claims abstract description 11
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