JP2005535644A - 安定な非経口パレコキシブ液体製剤 - Google Patents

安定な非経口パレコキシブ液体製剤 Download PDF

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JP2005535644A
JP2005535644A JP2004518239A JP2004518239A JP2005535644A JP 2005535644 A JP2005535644 A JP 2005535644A JP 2004518239 A JP2004518239 A JP 2004518239A JP 2004518239 A JP2004518239 A JP 2004518239A JP 2005535644 A JP2005535644 A JP 2005535644A
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parecoxib
composition
liquid solvent
salt
component
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JP2005535644A5 (enExample
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アール． ゴカーン，ヤティン
チャートマン，リチャード
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ファルマシア コーポレイション
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
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    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
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    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Ophthalmology & Optometry (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Hospice & Palliative Care (AREA)
  • Reproductive Health (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Oncology (AREA)
  • Obesity (AREA)
  • Gynecology & Obstetrics (AREA)
JP2004518239A 2002-06-26 2003-06-18 安定な非経口パレコキシブ液体製剤 Withdrawn JP2005535644A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US39171402P 2002-06-26 2002-06-26
PCT/US2003/021028 WO2004002533A1 (en) 2002-06-26 2003-06-18 Stable liquid parenteral parecoxib formulation

Publications (2)

Publication Number Publication Date
JP2005535644A true JP2005535644A (ja) 2005-11-24
JP2005535644A5 JP2005535644A5 (enExample) 2006-08-03

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ID=30000741

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JP2004518239A Withdrawn JP2005535644A (ja) 2002-06-26 2003-06-18 安定な非経口パレコキシブ液体製剤

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US (1) US20040127537A1 (enExample)
EP (1) EP1524997A1 (enExample)
JP (1) JP2005535644A (enExample)
AR (1) AR039747A1 (enExample)
AU (1) AU2003247793A1 (enExample)
BR (1) BR0312111A (enExample)
CA (1) CA2488526A1 (enExample)
MX (1) MXPA05000011A (enExample)
PA (1) PA8576601A1 (enExample)
PE (1) PE20040303A1 (enExample)
TW (1) TW200409645A (enExample)
WO (1) WO2004002533A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006517527A (ja) * 2002-12-30 2006-07-27 トランスフォーム・ファーマシューティカルズ・インコーポレイテッド 改善された溶解性を有する医薬組成物

Families Citing this family (9)

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CA2551523A1 (en) * 2003-12-24 2005-07-21 Pharmacia Corporation Metal salts of parecoxib as prodrugs of the cox-2 inhibitor valdecoxib for the treatment of inflammation, pain and/or fever
NZ568488A (en) 2005-12-22 2011-07-29 High Point Pharmaceuticals Llc Phenoxy acetic acids as PPAR delta activators
GB0612749D0 (en) * 2006-06-27 2006-08-09 Univ College London Hospitals Treatment and/or prevention of pain
DE102014115951A1 (de) * 2014-11-03 2016-05-04 Merlion Pharmaceuticals Pte Ltd. Zusammensetzungen, die Finafloxacin und Tris enthalten
CN104965041B (zh) * 2015-06-11 2016-06-29 成都克莱蒙医药科技有限公司 一种帕瑞昔布钠异构体的高效液相色谱检测方法
CN109568277B (zh) * 2019-01-30 2022-06-21 成都欣捷高新技术开发股份有限公司 枸橼酸在制备帕瑞昔布钠冻干制剂组合物中的应用及其组合物和制备方法
CN112409283A (zh) * 2020-11-24 2021-02-26 苏州璞正医药有限公司 一种帕瑞昔布衍生物及其制备方法和应用
WO2023214433A1 (en) * 2022-05-05 2023-11-09 Inventia Healthcare Limited Stable parenteral compositions of parecoxib
CN117003769B (zh) * 2023-07-11 2024-11-22 中国科学院宁波材料技术与工程研究所 氯诺昔康复合物、氯诺昔康-小檗碱共晶及其制备方法和应用

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Publication number Priority date Publication date Assignee Title
US5430057A (en) * 1993-09-30 1995-07-04 Board Of Regents, The University Of Texas System Parenteral busulfan for treatment of malignant disease
SE9501189D0 (sv) * 1995-03-31 1995-03-31 Pharmacia Ab Protein formulation
NZ320545A (en) * 1995-12-21 2000-03-27 Pfizer Injectable quinolone formulations
BR9708574A (pt) * 1996-04-12 1999-08-03 Searle & Co Derivados benzeno sulfonamida substituídos como pródrogas de inibidores cox-2
US6413965B1 (en) * 1999-06-30 2002-07-02 Pfizer Inc. Compositions and treatment for diabetic complications
CN1679556A (zh) * 1999-12-08 2005-10-12 法马西亚公司 维得克西组合物
JP2003523958A (ja) * 1999-12-23 2003-08-12 ニトロメド インコーポレーテッド ニトロソ化およびニトロシル化されたシクロオキシゲナーゼ−２の阻害剤、組成物ならびに使用法
GB0002336D0 (en) * 2000-02-01 2000-03-22 Glaxo Group Ltd Medicaments
US20020077328A1 (en) * 2000-07-13 2002-06-20 Fred Hassan Selective cyclooxygenase-2 inhibitors and vasomodulator compounds for generalized pain and headache pain
US20030105144A1 (en) * 2001-04-17 2003-06-05 Ping Gao Stabilized oral pharmaceutical composition

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006517527A (ja) * 2002-12-30 2006-07-27 トランスフォーム・ファーマシューティカルズ・インコーポレイテッド 改善された溶解性を有する医薬組成物

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PE20040303A1 (es) 2004-08-13
BR0312111A (pt) 2005-03-29
CA2488526A1 (en) 2004-01-08
WO2004002533A1 (en) 2004-01-08
MXPA05000011A (es) 2005-04-08
US20040127537A1 (en) 2004-07-01
AU2003247793A1 (en) 2004-01-19
PA8576601A1 (es) 2005-03-28
EP1524997A1 (en) 2005-04-27
TW200409645A (en) 2004-06-16
AR039747A1 (es) 2005-03-09

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