JP2005535644A - 安定な非経口パレコキシブ液体製剤 - Google Patents

安定な非経口パレコキシブ液体製剤 Download PDF

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JP2005535644A
JP2005535644A JP2004518239A JP2004518239A JP2005535644A JP 2005535644 A JP2005535644 A JP 2005535644A JP 2004518239 A JP2004518239 A JP 2004518239A JP 2004518239 A JP2004518239 A JP 2004518239A JP 2005535644 A JP2005535644 A JP 2005535644A
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parecoxib
composition
liquid solvent
salt
component
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JP2005535644A5 (enExample
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アール． ゴカーン，ヤティン
チャートマン，リチャード
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ファルマシア コーポレイション
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Reproductive Health (AREA)
  • Emergency Medicine (AREA)
  • Toxicology (AREA)
JP2004518239A 2002-06-26 2003-06-18 安定な非経口パレコキシブ液体製剤 Withdrawn JP2005535644A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US39171402P 2002-06-26 2002-06-26
PCT/US2003/021028 WO2004002533A1 (en) 2002-06-26 2003-06-18 Stable liquid parenteral parecoxib formulation

Publications (2)

Publication Number Publication Date
JP2005535644A true JP2005535644A (ja) 2005-11-24
JP2005535644A5 JP2005535644A5 (enExample) 2006-08-03

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ID=30000741

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Application Number Title Priority Date Filing Date
JP2004518239A Withdrawn JP2005535644A (ja) 2002-06-26 2003-06-18 安定な非経口パレコキシブ液体製剤

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US (1) US20040127537A1 (enExample)
EP (1) EP1524997A1 (enExample)
JP (1) JP2005535644A (enExample)
AR (1) AR039747A1 (enExample)
AU (1) AU2003247793A1 (enExample)
BR (1) BR0312111A (enExample)
CA (1) CA2488526A1 (enExample)
MX (1) MXPA05000011A (enExample)
PA (1) PA8576601A1 (enExample)
PE (1) PE20040303A1 (enExample)
TW (1) TW200409645A (enExample)
WO (1) WO2004002533A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006517527A (ja) * 2002-12-30 2006-07-27 トランスフォーム・ファーマシューティカルズ・インコーポレイテッド 改善された溶解性を有する医薬組成物

Families Citing this family (9)

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Publication number Priority date Publication date Assignee Title
CA2551523A1 (en) * 2003-12-24 2005-07-21 Pharmacia Corporation Metal salts of parecoxib as prodrugs of the cox-2 inhibitor valdecoxib for the treatment of inflammation, pain and/or fever
EA201101085A1 (ru) 2005-12-22 2012-05-30 ХАЙ ПОЙНТ ФАРМАСЬЮТИКАЛЗ, ЭлЭлСи Феноксиуксусные кислоты в качестве активаторов ppar дельта
GB0612749D0 (en) * 2006-06-27 2006-08-09 Univ College London Hospitals Treatment and/or prevention of pain
DE102014115951A1 (de) * 2014-11-03 2016-05-04 Merlion Pharmaceuticals Pte Ltd. Zusammensetzungen, die Finafloxacin und Tris enthalten
CN104965041B (zh) * 2015-06-11 2016-06-29 成都克莱蒙医药科技有限公司 一种帕瑞昔布钠异构体的高效液相色谱检测方法
CN109568277B (zh) * 2019-01-30 2022-06-21 成都欣捷高新技术开发股份有限公司 枸橼酸在制备帕瑞昔布钠冻干制剂组合物中的应用及其组合物和制备方法
CN112409283A (zh) * 2020-11-24 2021-02-26 苏州璞正医药有限公司 一种帕瑞昔布衍生物及其制备方法和应用
WO2023214433A1 (en) * 2022-05-05 2023-11-09 Inventia Healthcare Limited Stable parenteral compositions of parecoxib
CN117003769B (zh) * 2023-07-11 2024-11-22 中国科学院宁波材料技术与工程研究所 氯诺昔康复合物、氯诺昔康-小檗碱共晶及其制备方法和应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5430057A (en) * 1993-09-30 1995-07-04 Board Of Regents, The University Of Texas System Parenteral busulfan for treatment of malignant disease
SE9501189D0 (sv) * 1995-03-31 1995-03-31 Pharmacia Ab Protein formulation
CZ293747B6 (cs) * 1995-12-21 2004-07-14 Pfizer Inc. Vodný farmaceutický roztok vhodný pro injekční podávání hostiteli a jeho použití
GEP20032998B (en) * 1996-04-12 2003-06-25 Searle & Co Substituted Benzenesulfonamide Derivatives as Prodrugs of Cox-2 Inhibitors
US6413965B1 (en) * 1999-06-30 2002-07-02 Pfizer Inc. Compositions and treatment for diabetic complications
HRP20010582A2 (en) * 1999-12-08 2002-08-31 Pharmacia Corp Valdecoxib compositions
JP2003523958A (ja) * 1999-12-23 2003-08-12 ニトロメド インコーポレーテッド ニトロソ化およびニトロシル化されたシクロオキシゲナーゼ−２の阻害剤、組成物ならびに使用法
GB0002336D0 (en) * 2000-02-01 2000-03-22 Glaxo Group Ltd Medicaments
CA2415697A1 (en) * 2000-07-13 2002-01-24 James C. Forbes Combination of a cox-2 inhibitor and a vasomodulator for treating pain and headache pain
US20030105144A1 (en) * 2001-04-17 2003-06-05 Ping Gao Stabilized oral pharmaceutical composition

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006517527A (ja) * 2002-12-30 2006-07-27 トランスフォーム・ファーマシューティカルズ・インコーポレイテッド 改善された溶解性を有する医薬組成物

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CA2488526A1 (en) 2004-01-08
EP1524997A1 (en) 2005-04-27
US20040127537A1 (en) 2004-07-01
WO2004002533A1 (en) 2004-01-08
TW200409645A (en) 2004-06-16
PE20040303A1 (es) 2004-08-13
AR039747A1 (es) 2005-03-09
PA8576601A1 (es) 2005-03-28
AU2003247793A1 (en) 2004-01-19
BR0312111A (pt) 2005-03-29
MXPA05000011A (es) 2005-04-08

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