TR201910347T4 - Olanzapin haptenlerine yönelik antikorlar ve bunların kullanımı. - Google Patents

Olanzapin haptenlerine yönelik antikorlar ve bunların kullanımı. Download PDF

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Publication number
TR201910347T4
TR201910347T4 TR2019/10347T TR201910347T TR201910347T4 TR 201910347 T4 TR201910347 T4 TR 201910347T4 TR 2019/10347 T TR2019/10347 T TR 2019/10347T TR 201910347 T TR201910347 T TR 201910347T TR 201910347 T4 TR201910347 T4 TR 201910347T4
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TR
Turkey
Prior art keywords
antibody
olanzapine
reaction
sample
group
Prior art date
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TR2019/10347T
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English (en)
Turkish (tr)
Inventor
Hryhorenko Eric
Sankaran Banumathi
R Decory Thomas
Tubbs Theresa
Colt Linda
M Remmerie Bart
Salter Rhys
Garrett Donahue Matthew
Gong Yong
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Janssen Pharmaceutica Nv
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Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of TR201910347T4 publication Critical patent/TR201910347T4/tr

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • G01N33/948Sedatives, e.g. cannabinoids, barbiturates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/44Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/02Preparation of hybrid cells by fusion of two or more cells, e.g. protoplast fusion
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10Cells modified by introduction of foreign genetic material
    • C12N5/12Fused cells, e.g. hybridomas
    • C12N5/16Animal cells
    • C12N5/163Animal cells one of the fusion partners being a B or a T lymphocyte
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/30Psychoses; Psychiatry
    • G01N2800/302Schizophrenia

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Plant Pathology (AREA)
  • Anesthesiology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
TR2019/10347T 2012-08-21 2013-08-20 Olanzapin haptenlerine yönelik antikorlar ve bunların kullanımı. TR201910347T4 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201261691572P 2012-08-21 2012-08-21

Publications (1)

Publication Number Publication Date
TR201910347T4 true TR201910347T4 (tr) 2019-07-22

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TR2019/10347T TR201910347T4 (tr) 2012-08-21 2013-08-20 Olanzapin haptenlerine yönelik antikorlar ve bunların kullanımı.

Country Status (11)

Country Link
US (3) US20140057303A1 (enExample)
EP (2) EP3581195B1 (enExample)
JP (2) JP6389177B2 (enExample)
CN (2) CN109400708A (enExample)
AU (3) AU2013305895B2 (enExample)
CA (1) CA2882595C (enExample)
ES (1) ES2733963T3 (enExample)
PL (1) PL2887952T3 (enExample)
PT (1) PT2887952T (enExample)
TR (1) TR201910347T4 (enExample)
WO (1) WO2014031656A1 (enExample)

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EP2888277A4 (en) 2012-08-21 2016-05-18 Ortho Clinical Diagnostics Inc ANTIBODIES AGAINST PALIPERIDONE AND USE THEREOF
PT2888593T (pt) 2012-08-21 2018-12-12 Janssen Pharmaceutica Nv Anticorpos contra risperidona e utilizações dos mesmos
CA2882489A1 (en) 2012-08-21 2014-02-27 Ortho-Clinical Diagnostics, Inc. Antibodies to paliperidone haptens and use thereof
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CN105601730A (zh) * 2014-10-30 2016-05-25 北京维德维康生物技术有限公司 呋喃妥因半抗原和抗原的制备方法及其在化学发光免疫试剂盒中的应用
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CN110938082A (zh) * 2019-10-30 2020-03-31 杭州博拓生物科技股份有限公司 一种奥氮平人工抗原及其制备方法
CN114685527B (zh) * 2020-12-25 2024-03-05 长沙博源医疗科技有限公司 一种奥氮平衍生物、免疫原、抗奥氮平特异性抗体及其制备方法与应用
CN115073492B (zh) * 2022-08-22 2022-11-18 北京丹大生物技术有限公司 一种奥氮平衍生物抗原、奥氮平抗体及其应用
CN119662553B (zh) * 2024-11-26 2025-11-28 江南大学 一种分泌奥氮平类化合物单克隆抗体的杂交瘤细胞株

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JP2019004889A (ja) 2019-01-17
AU2013305895A1 (en) 2015-03-05
HK1211857A1 (en) 2016-06-03
AU2018200435A1 (en) 2018-02-08
US20170240653A1 (en) 2017-08-24
AU2019283807A1 (en) 2020-01-16
US20170343569A1 (en) 2017-11-30
CN109400708A (zh) 2019-03-01
AU2018200435B2 (en) 2019-09-19
WO2014031656A1 (en) 2014-02-27
CN104755093B (zh) 2018-11-16
US10712353B2 (en) 2020-07-14
JP6721641B2 (ja) 2020-07-15
CA2882595C (en) 2019-06-04
EP2887952A1 (en) 2015-07-01
CA2882595A1 (en) 2014-02-27
JP6389177B2 (ja) 2018-09-12
US20140057303A1 (en) 2014-02-27
JP2015529201A (ja) 2015-10-05
US11226345B2 (en) 2022-01-18
AU2013305895B2 (en) 2017-10-19
EP3581195B1 (en) 2025-10-01
PL2887952T3 (pl) 2019-11-29
EP3581195A1 (en) 2019-12-18
CN104755093A (zh) 2015-07-01
EP2887952A4 (en) 2016-04-13
AU2019283807B2 (en) 2021-04-29
EP2887952B1 (en) 2019-05-15
PT2887952T (pt) 2019-08-30
ES2733963T3 (es) 2019-12-03

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