AU2013305895B2 - Antibodies to olanzapine haptens and use thereof - Google Patents

Antibodies to olanzapine haptens and use thereof Download PDF

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Publication number
AU2013305895B2
AU2013305895B2 AU2013305895A AU2013305895A AU2013305895B2 AU 2013305895 B2 AU2013305895 B2 AU 2013305895B2 AU 2013305895 A AU2013305895 A AU 2013305895A AU 2013305895 A AU2013305895 A AU 2013305895A AU 2013305895 B2 AU2013305895 B2 AU 2013305895B2
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Prior art keywords
olanzapine
antibody
group
sample
labeled
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AU2013305895A
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AU2013305895A1 (en
Inventor
Linda COLT
Thomas R. DECORY
Matthew Garrett DONAHUE
Yong Gong
Eric Hryhorenko
Bart M. REMMERIE
Rhys Salter
Banumathi Sankaran
Theresa TUBBS
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Saladax Biomedical Inc
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Saladax Biomedical Inc
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Publication of AU2013305895A1 publication Critical patent/AU2013305895A1/en
Assigned to JANSSEN PHARMACEUTICA NV reassignment JANSSEN PHARMACEUTICA NV Request for Assignment Assignors: JANSSEN PHARMACEUTICA NV, ORTHO-CLINICAL DIAGNOSTICS, INC
Application granted granted Critical
Publication of AU2013305895B2 publication Critical patent/AU2013305895B2/en
Priority to AU2018200435A priority Critical patent/AU2018200435B2/en
Priority to AU2019283807A priority patent/AU2019283807B2/en
Assigned to SALADAX BIOMEDICAL INC. reassignment SALADAX BIOMEDICAL INC. Request for Assignment Assignors: JANSSEN PHARMACEUTICA NV
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • G01N33/948—Sedatives, e.g. cannabinoids, barbiturates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/44—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/02—Preparation of hybrid cells by fusion of two or more cells, e.g. protoplast fusion
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C12N5/12—Fused cells, e.g. hybridomas
    • C12N5/16—Animal cells
    • C12N5/163—Animal cells one of the fusion partners being a B or a T lymphocyte
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/30—Psychoses; Psychiatry
    • G01N2800/302—Schizophrenia

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Plant Pathology (AREA)
  • Anesthesiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
AU2013305895A 2012-08-21 2013-08-20 Antibodies to olanzapine haptens and use thereof Active AU2013305895B2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU2018200435A AU2018200435B2 (en) 2012-08-21 2018-01-19 Antibodies to olanzapine haptens and use thereof
AU2019283807A AU2019283807B2 (en) 2012-08-21 2019-12-17 Antibodies to olanzapine haptens and use thereof

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261691572P 2012-08-21 2012-08-21
US61/691,572 2012-08-21
PCT/US2013/055817 WO2014031656A1 (en) 2012-08-21 2013-08-20 Antibodies to olanzapine haptens and use thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2018200435A Division AU2018200435B2 (en) 2012-08-21 2018-01-19 Antibodies to olanzapine haptens and use thereof

Publications (2)

Publication Number Publication Date
AU2013305895A1 AU2013305895A1 (en) 2015-03-05
AU2013305895B2 true AU2013305895B2 (en) 2017-10-19

Family

ID=50148310

Family Applications (3)

Application Number Title Priority Date Filing Date
AU2013305895A Active AU2013305895B2 (en) 2012-08-21 2013-08-20 Antibodies to olanzapine haptens and use thereof
AU2018200435A Active AU2018200435B2 (en) 2012-08-21 2018-01-19 Antibodies to olanzapine haptens and use thereof
AU2019283807A Active AU2019283807B2 (en) 2012-08-21 2019-12-17 Antibodies to olanzapine haptens and use thereof

Family Applications After (2)

Application Number Title Priority Date Filing Date
AU2018200435A Active AU2018200435B2 (en) 2012-08-21 2018-01-19 Antibodies to olanzapine haptens and use thereof
AU2019283807A Active AU2019283807B2 (en) 2012-08-21 2019-12-17 Antibodies to olanzapine haptens and use thereof

Country Status (11)

Country Link
US (3) US20140057303A1 (enExample)
EP (2) EP2887952B1 (enExample)
JP (2) JP6389177B2 (enExample)
CN (2) CN104755093B (enExample)
AU (3) AU2013305895B2 (enExample)
CA (1) CA2882595C (enExample)
ES (2) ES3057437T3 (enExample)
PL (1) PL2887952T3 (enExample)
PT (1) PT2887952T (enExample)
TR (1) TR201910347T4 (enExample)
WO (1) WO2014031656A1 (enExample)

Families Citing this family (18)

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JP2015529199A (ja) 2012-08-21 2015-10-05 オルソ−クリニカル ダイアグノスティクス，インコーポレイティド パリペリドンハプテンに対する抗体及びその使用
EP2888284B1 (en) 2012-08-21 2022-07-06 Janssen Pharmaceutica NV Antibodies to risperidone haptens and use thereof
PL2888592T3 (pl) 2012-08-21 2018-03-30 Janssen Pharmaceutica Nv Przeciwciała względem kwetiapiny i ich zastosowania
JP6131414B2 (ja) 2012-08-21 2017-05-24 ヤンセン ファーマシューティカ エヌ．ベー． アリピプラゾールのハプテン及びイムノアッセイにおけるそれらの使用
CA2882596C (en) 2012-08-21 2019-05-14 Ortho-Clinical Diagnostics, Inc. Antibodies to olanzapine and use thereof
WO2014031656A1 (en) 2012-08-21 2014-02-27 Ortho-Clinical Diagnostics, Inc Antibodies to olanzapine haptens and use thereof
CA2882562C (en) 2012-08-21 2019-08-27 Eric Hryhorenko Antibodies to aripiprazole and use thereof
ES2691092T3 (es) 2012-08-21 2018-11-23 Janssen Pharmaceutica Nv Anticuerpos contra la risperidona y uso de los mismos
JP2015527365A (ja) 2012-08-21 2015-09-17 オルソ−クリニカル ダイアグノスティクス，インコーポレイティド パリペリドンに対する抗体及びその使用
JP6389176B2 (ja) 2012-08-21 2018-09-12 ヤンセン ファーマシューティカ エヌ．ベー． アリピプラゾールハプテンに対する抗体及びその使用
JP6450314B2 (ja) 2012-08-21 2019-01-09 ヤンセン ファーマシューティカ エヌ．ベー． クエチアピンハプテンに対する抗体及びその使用
CN105601730A (zh) * 2014-10-30 2016-05-25 北京维德维康生物技术有限公司 呋喃妥因半抗原和抗原的制备方法及其在化学发光免疫试剂盒中的应用
EP3390449A1 (en) 2015-12-17 2018-10-24 Janssen Pharmaceutica N.V. Antibodies to risperidone and use thereof
US10435478B2 (en) 2015-12-17 2019-10-08 Janssen Pharmaceutica Nv Antibodies to quetiapine and use thereof
CN110938082A (zh) * 2019-10-30 2020-03-31 杭州博拓生物科技股份有限公司 一种奥氮平人工抗原及其制备方法
CN114685527B (zh) * 2020-12-25 2024-03-05 长沙博源医疗科技有限公司 一种奥氮平衍生物、免疫原、抗奥氮平特异性抗体及其制备方法与应用
CN115073492B (zh) * 2022-08-22 2022-11-18 北京丹大生物技术有限公司 一种奥氮平衍生物抗原、奥氮平抗体及其应用
CN119662553B (zh) * 2024-11-26 2025-11-28 江南大学 一种分泌奥氮平类化合物单克隆抗体的杂交瘤细胞株

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EP2888284B1 (en) 2012-08-21 2022-07-06 Janssen Pharmaceutica NV Antibodies to risperidone haptens and use thereof
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