TR201802689T4 - Glukagon benzeri peptit-2 (glp-2) analogları. - Google Patents
Glukagon benzeri peptit-2 (glp-2) analogları. Download PDFInfo
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- TR201802689T4 TR201802689T4 TR2018/02689T TR201802689T TR201802689T4 TR 201802689 T4 TR201802689 T4 TR 201802689T4 TR 2018/02689 T TR2018/02689 T TR 2018/02689T TR 201802689 T TR201802689 T TR 201802689T TR 201802689 T4 TR201802689 T4 TR 201802689T4
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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| UA116217C2 (uk) | 2012-10-09 | 2018-02-26 | Санофі | Пептидна сполука як подвійний агоніст рецепторів glp1-1 та глюкагону |
| RU2652783C2 (ru) | 2012-12-21 | 2018-05-03 | Санофи | Двойные агонисты glp1/gip или тройные агонисты glp1/gip/глюкагона |
| KR102394515B1 (ko) | 2013-10-17 | 2022-05-09 | 질랜드 파마 에이/에스 | 아실화된 글루카곤 유사체 |
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| KR102310392B1 (ko) | 2013-11-06 | 2021-10-13 | 질랜드 파마 에이/에스 | 글루카곤-ｇｌｐ-1-ｇｉｐ 삼원 효능제 화합물 |
| EP3080150B1 (en) | 2013-12-13 | 2018-08-01 | Sanofi | Exendin-4 peptide analogues as dual glp-1/gip receptor agonists |
| WO2015086730A1 (en) | 2013-12-13 | 2015-06-18 | Sanofi | Non-acylated exendin-4 peptide analogues |
| EP3080149A1 (en) | 2013-12-13 | 2016-10-19 | Sanofi | Dual glp-1/glucagon receptor agonists |
| EP3080154B1 (en) | 2013-12-13 | 2018-02-07 | Sanofi | Dual glp-1/gip receptor agonists |
| EP3080155A1 (en) * | 2013-12-13 | 2016-10-19 | Sanofi | Exendin-4 peptide analogues as dual glp-1/glucagon receptor agonists |
| TW201625669A (zh) | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | 衍生自艾塞那肽－４（Ｅｘｅｎｄｉｎ－４）之肽類雙重ＧＬＰ－１／升糖素受體促效劑 |
| TW201625670A (zh) | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | 衍生自ｅｘｅｎｄｉｎ－４之雙重ｇｌｐ－１／升糖素受體促效劑 |
| TW201625668A (zh) | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | 作為胜肽性雙重ｇｌｐ－１／昇糖素受體激動劑之艾塞那肽－４衍生物 |
| US9932381B2 (en) | 2014-06-18 | 2018-04-03 | Sanofi | Exendin-4 derivatives as selective glucagon receptor agonists |
| DK3212218T3 (da) | 2014-10-29 | 2021-08-30 | Zealand Pharma As | GIP-agonistforbindelser og fremgangsmåder |
| US20180280480A1 (en) * | 2014-10-31 | 2018-10-04 | Gubra Aps | Compositions and peptides having dual glp-1r and glp-2r agonist activity |
| EP3283507B8 (en) | 2015-04-16 | 2019-11-13 | Zealand Pharma A/S | Acylated glucagon analogue |
| AR105319A1 (es) | 2015-06-05 | 2017-09-27 | Sanofi Sa | Profármacos que comprenden un conjugado agonista dual de glp-1 / glucagón conector ácido hialurónico |
| AR105284A1 (es) | 2015-07-10 | 2017-09-20 | Sanofi Sa | Derivados de exendina-4 como agonistas peptídicos duales específicos de los receptores de glp-1 / glucagón |
| LT3393496T (lt) | 2015-12-23 | 2023-12-11 | The Johns Hopkins University | Ilgo veikimo glp-1r agonistas, kaip neurologinių ir neurodegeneracinių būklių terapija |
| JP6700150B2 (ja) * | 2016-10-03 | 2020-05-27 | 東京エレクトロン株式会社 | パーティクル捕集装置、パーティクル捕集方法、およびパーティクル捕集システム |
| BR112019010624A2 (pt) * | 2016-12-09 | 2019-10-22 | Zealand Pharma As | agonistas duplos de glp-1/glp-2 acilados e composição |
| WO2018104558A1 (en) | 2016-12-09 | 2018-06-14 | Zealand Pharma A/S | Acylated glp-1/glp-2 dual agonists |
| RU2756011C2 (ru) * | 2016-12-09 | 2021-09-24 | Зилэнд Фарма А/С | Glp-1/glp-2 двойные агонисты |
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| WO2018104559A1 (en) | 2016-12-09 | 2018-06-14 | Zealand Pharma A/S | Glp-1/glp-2 dual agonists |
| IL299864B2 (en) * | 2017-06-16 | 2024-06-01 | Zealand Pharma As | Dosage regimes for the administration of glucagon-like-peptide-2 (glp-2) analogues |
| GB201710822D0 (en) * | 2017-07-05 | 2017-08-16 | Zealand Pharma As | Methods and medical uses relating to the treatment of hypoglycaemia |
| WO2019090209A1 (en) | 2017-11-06 | 2019-05-09 | Shire-Nps Pharmaceuticals, Inc. | Glp-2 analogs and peptibodies for administration before during, or after surgery |
| WO2020020904A1 (en) | 2018-07-23 | 2020-01-30 | Zealand Pharma A/S | Therapeutic uses of glp-2 agonists |
| KR20210126088A (ko) | 2019-02-11 | 2021-10-19 | 옵코 바이오로직스 리미티드 | 지속성 glp-2 유사체 |
| AU2020293576B2 (en) | 2019-06-14 | 2025-04-10 | Zealand Pharma A/S | Pharmaceutical parenteral composition of dual GLP1/2 agonist |
| CA3156985A1 (en) | 2019-10-07 | 2021-04-15 | Kallyope, Inc. | Gpr119 agonists |
| CN111329995B (zh) * | 2020-02-18 | 2022-11-11 | 河南中医药大学 | Glp-2类似物在制备防治pd药物中的应用及防治pd的药物 |
| JP7745559B2 (ja) | 2020-02-28 | 2025-09-29 | キャリーオペ，インク． | Ｇｐｒ４０アゴニスト |
| JP2023520498A (ja) * | 2020-04-03 | 2023-05-17 | ハンミ ファーマシューティカル カンパニー リミテッド | Ｇｌｐ－２誘導体またはその持続型結合体を含む放射線療法、化学療法、またはこれらの組合わせにより誘発された粘膜炎の予防または治療用薬学的組成物 |
| CA3178994A1 (en) | 2020-05-19 | 2021-11-25 | Iyassu Sebhat | Ampk activators |
| CN116157413A (zh) | 2020-06-09 | 2023-05-23 | 维克蒂生物股份有限公司 | 阿普拉鲁肽的制造、配制和给药 |
| CN116390925A (zh) | 2020-06-26 | 2023-07-04 | 卡尔优普公司 | Ampk活化剂 |
| AU2023346836A1 (en) | 2022-09-19 | 2025-03-20 | Zealand Pharma A/S | Combination therapy |
| CN116478269A (zh) * | 2023-04-28 | 2023-07-25 | 成都奥达生物科技有限公司 | 一种长效替度鲁肽化合物 |
| CN118146350B (zh) * | 2024-03-13 | 2024-10-22 | 北京泽勤生物医药有限公司 | Glp-2肽类似物的制备方法及应用 |
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| KR101242951B1 (ko) | 2005-05-04 | 2013-03-13 | 질랜드 파마 에이/에스 | 글루카곤 유사 펩티드-2(ｇｌｐ-2) 유사체 |
| AU2007319066B2 (en) | 2006-11-08 | 2013-09-19 | Zealand Pharma A/S | Selective glucagon-like-peptide-2 (GLP-2) analogues |
| UA104605C2 (uk) * | 2008-12-15 | 2014-02-25 | Зіленд Фарма А/С | Аналоги глюкагону |
| AR081975A1 (es) * | 2010-06-23 | 2012-10-31 | Zealand Pharma As | Analogos de glucagon |
| WO2012158965A2 (en) * | 2011-05-18 | 2012-11-22 | Mederis Diabetes, Llc | Improved peptide pharmaceuticals for insulin resistance |
| AU2013255752B2 (en) | 2012-05-03 | 2017-11-09 | Zealand Pharma A/S | Glucagon-like-peptide-2 (GLP-2) analogues |
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| AU2013255752A1 (en) | 2014-12-18 |
| BR112014027345A2 (pt) | 2019-09-03 |
| US9453064B2 (en) | 2016-09-27 |
| AU2013255752B2 (en) | 2017-11-09 |
| KR20150006052A (ko) | 2015-01-15 |
| JP2015517299A (ja) | 2015-06-22 |
| JP6298044B2 (ja) | 2018-03-20 |
| US9969787B2 (en) | 2018-05-15 |
| EP2844670B1 (en) | 2017-12-06 |
| MX2014013319A (es) | 2015-07-06 |
| CN104540850A (zh) | 2015-04-22 |
| CN104540850B (zh) | 2018-05-18 |
| CA2872315A1 (en) | 2013-11-07 |
| HK1208238A1 (en) | 2016-02-26 |
| EA028929B1 (ru) | 2018-01-31 |
| US20150125431A1 (en) | 2015-05-07 |
| WO2013164484A1 (en) | 2013-11-07 |
| US10253080B2 (en) | 2019-04-09 |
| IN2014DN09782A (enExample) | 2015-07-31 |
| EA201491934A1 (ru) | 2015-07-30 |
| US20180298077A1 (en) | 2018-10-18 |
| US20160355563A1 (en) | 2016-12-08 |
| EP2844670A1 (en) | 2015-03-11 |
| MX356958B (es) | 2018-06-20 |
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