TR200603833T2 - 7-karboksimetiloksi-3',4',5-trimetoksi flavon-monohidrat, hazırlama metodu ve kullanılması - Google Patents
7-karboksimetiloksi-3',4',5-trimetoksi flavon-monohidrat, hazırlama metodu ve kullanılmasıInfo
- Publication number
- TR200603833T2 TR200603833T2 TR2006/03833T TR200603833T TR200603833T2 TR 200603833 T2 TR200603833 T2 TR 200603833T2 TR 2006/03833 T TR2006/03833 T TR 2006/03833T TR 200603833 T TR200603833 T TR 200603833T TR 200603833 T2 TR200603833 T2 TR 200603833T2
- Authority
- TR
- Turkey
- Prior art keywords
- carboxymethyloxy
- preparation
- monohydrate
- trimethoxy
- flavon
- Prior art date
Links
- 238000002360 preparation method Methods 0.000 title abstract 3
- QPRWFGRYMWXLPH-UHFFFAOYSA-N 2-phenylchromen-4-one;hydrate Chemical compound O.O1C2=CC=CC=C2C(=O)C=C1C1=CC=CC=C1 QPRWFGRYMWXLPH-UHFFFAOYSA-N 0.000 title 1
- FVVKFCKXYJWGDM-UHFFFAOYSA-N 2-[2-(3,4-dimethoxyphenyl)-5-methoxy-4-oxochromen-7-yl]oxyacetic acid;hydrate Chemical compound O.C1=C(OC)C(OC)=CC=C1C1=CC(=O)C2=C(OC)C=C(OCC(O)=O)C=C2O1 FVVKFCKXYJWGDM-UHFFFAOYSA-N 0.000 abstract 1
- 210000001072 colon Anatomy 0.000 abstract 1
- 210000001035 gastrointestinal tract Anatomy 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000001681 protective effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
- C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
- C07D311/28—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only
- C07D311/30—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only not hydrogenated in the hetero ring, e.g. flavones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrane Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Saccharide Compounds (AREA)
Abstract
Bu buluş kolon dahil gastroentestınal yol için koruyucu bir faaliyete sahip ölçülü dozda 7-karboksimetiloksi-3'4'5-trimetoksi flavon hazırlanması için uygun bir higroskopik olmayan ürün olan 7-karboksimetiloksi-3',4',5-trimetoksi flavon.monohidrat ile ve bunun hazırlanma metodu ve kullanımları ile ilgilidir.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1020030061938A KR20050024121A (ko) | 2003-09-04 | 2003-09-04 | 7-카르복시메틸옥시-3',4',5-트리메톡시 플라본.일수화물, 이의 제조방법 및 용도 |
Publications (1)
Publication Number | Publication Date |
---|---|
TR200603833T2 true TR200603833T2 (tr) | 2006-11-21 |
Family
ID=36087516
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR2006/00987T TR200600987T1 (tr) | 2003-09-04 | 2004-09-04 | 7-karboksimetiloksi-3',4',5-trimetoksi flavon-monohidrat, hazırlama metodu ve kullanılması |
TR2006/03833T TR200603833T2 (tr) | 2003-09-04 | 2004-09-04 | 7-karboksimetiloksi-3',4',5-trimetoksi flavon-monohidrat, hazırlama metodu ve kullanılması |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR2006/00987T TR200600987T1 (tr) | 2003-09-04 | 2004-09-04 | 7-karboksimetiloksi-3',4',5-trimetoksi flavon-monohidrat, hazırlama metodu ve kullanılması |
Country Status (20)
Country | Link |
---|---|
US (1) | US7371775B2 (tr) |
EP (2) | EP2065375A1 (tr) |
JP (2) | JP2007504217A (tr) |
KR (2) | KR20050024121A (tr) |
CN (2) | CN100591332C (tr) |
AT (1) | ATE451918T1 (tr) |
AU (1) | AU2004270065B2 (tr) |
BR (1) | BRPI0413163A (tr) |
CA (1) | CA2533301C (tr) |
DE (1) | DE602004024687D1 (tr) |
DK (1) | DK1660074T3 (tr) |
ES (1) | ES2336000T3 (tr) |
HK (1) | HK1089962A1 (tr) |
MX (1) | MXPA06002383A (tr) |
NZ (2) | NZ575796A (tr) |
PT (1) | PT1660074E (tr) |
RU (1) | RU2302416C2 (tr) |
SG (1) | SG136960A1 (tr) |
TR (2) | TR200600987T1 (tr) |
WO (1) | WO2005023244A1 (tr) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100930467B1 (ko) * | 2007-06-07 | 2009-12-08 | 동아제약주식회사 | 점액분비를 촉진시키는 3',4',5-트리메톡시 플라본 유도체화합물, 그의 제조방법 및 약학적 용도 |
KR101381999B1 (ko) * | 2007-07-06 | 2014-04-14 | 동아에스티 주식회사 | 위염 치료제의 효력을 극대화시키기 위한 가용화 위체류시스템 매트릭스 제제 |
KR20110010753A (ko) * | 2008-05-08 | 2011-02-07 | 유나이티드 세러퓨틱스 코오포레이션 | 트레프로스티닐 일수화물 |
JP7121986B2 (ja) * | 2018-08-16 | 2022-08-19 | 株式会社常磐植物化学研究所 | アルコキシフラボン誘導体の製造方法 |
JP2024528234A (ja) | 2021-08-05 | 2024-07-26 | ジーエル・ファームテック・コーポレイション | レコフラボン(recoflavone)を含有するドライアイ症候群を処置するための点眼組成物及びそれを製造するための方法 |
KR102583151B1 (ko) | 2021-08-05 | 2023-09-26 | 지엘팜텍주식회사 | 안구건조증 치료를 위한 레코플라본 함유 점안 조성물 및 이의 제조방법 |
KR102356603B1 (ko) | 2021-08-05 | 2022-02-08 | 지엘팜텍주식회사 | 안구건조증 치료를 위한 레코플라본 함유 점안 조성물 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2623808B1 (fr) * | 1987-12-01 | 1990-03-09 | Adir | Nouveaux derives flavonoides (benzyl-4 piperazinyl-1)-2 oxo-2 ethylene substitues, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent |
IT1245371B (it) * | 1991-03-28 | 1994-09-20 | Geymonat Spa | Derivati di flavoni, procedimento per la loro preparazione e composizioni farmaceutiche che li contengono |
US5399584A (en) * | 1992-05-05 | 1995-03-21 | The Procter & Gamble Company | Use of flavone derivatives for gastroprotection |
US5525072A (en) | 1995-01-10 | 1996-06-11 | Molex Incorporated | Electrical connector assembly for interconnecting a flat cable to a circuit board |
KR100447918B1 (ko) * | 1996-07-25 | 2005-09-28 | 동아제약주식회사 | 대장을포함한위장관보호작용을갖는플라본및플라바논화합물 |
KR19990041205A (ko) | 1997-11-21 | 1999-06-15 | 이종수 | 전자 브레이크장치 |
KR100327621B1 (ko) * | 1999-09-22 | 2002-03-15 | 유충식 | 7-카르복시메틸옥시-3',4',5-트리메톡시플라본의 제조방법 |
-
2003
- 2003-09-04 KR KR1020030061938A patent/KR20050024121A/ko not_active Application Discontinuation
-
2004
- 2004-09-04 PT PT04774508T patent/PT1660074E/pt unknown
- 2004-09-04 KR KR1020057016164A patent/KR100644928B1/ko active IP Right Grant
- 2004-09-04 ES ES04774508T patent/ES2336000T3/es not_active Expired - Lifetime
- 2004-09-04 AU AU2004270065A patent/AU2004270065B2/en not_active Ceased
- 2004-09-04 RU RU2006102956/04A patent/RU2302416C2/ru not_active IP Right Cessation
- 2004-09-04 NZ NZ575796A patent/NZ575796A/en not_active IP Right Cessation
- 2004-09-04 CA CA2533301A patent/CA2533301C/en not_active Expired - Fee Related
- 2004-09-04 NZ NZ544761A patent/NZ544761A/en not_active IP Right Cessation
- 2004-09-04 AT AT04774508T patent/ATE451918T1/de active
- 2004-09-04 JP JP2006525281A patent/JP2007504217A/ja active Pending
- 2004-09-04 BR BRPI0413163-0A patent/BRPI0413163A/pt not_active IP Right Cessation
- 2004-09-04 CN CN200480020608A patent/CN100591332C/zh not_active Expired - Fee Related
- 2004-09-04 WO PCT/KR2004/002247 patent/WO2005023244A1/en active IP Right Grant
- 2004-09-04 MX MXPA06002383A patent/MXPA06002383A/es active IP Right Grant
- 2004-09-04 DE DE602004024687T patent/DE602004024687D1/de not_active Expired - Lifetime
- 2004-09-04 DK DK04774508.8T patent/DK1660074T3/da active
- 2004-09-04 US US10/564,128 patent/US7371775B2/en not_active Expired - Fee Related
- 2004-09-04 EP EP08019101A patent/EP2065375A1/en not_active Withdrawn
- 2004-09-04 EP EP04774508A patent/EP1660074B1/en not_active Expired - Lifetime
- 2004-09-04 CN CN2009102043829A patent/CN101684113B/zh not_active Expired - Fee Related
- 2004-09-04 TR TR2006/00987T patent/TR200600987T1/tr unknown
- 2004-09-04 TR TR2006/03833T patent/TR200603833T2/tr unknown
- 2004-09-04 SG SG200717035-0A patent/SG136960A1/en unknown
-
2006
- 2006-09-26 HK HK06110706.8A patent/HK1089962A1/xx not_active IP Right Cessation
-
2010
- 2010-03-08 JP JP2010051121A patent/JP2010138193A/ja active Pending
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