TR200200435T2 - Yeni makrolit antibiyotikler. - Google Patents

Yeni makrolit antibiyotikler.

Info

Publication number
TR200200435T2
TR200200435T2 TR2002/00435T TR200200435T TR200200435T2 TR 200200435 T2 TR200200435 T2 TR 200200435T2 TR 2002/00435 T TR2002/00435 T TR 2002/00435T TR 200200435 T TR200200435 T TR 200200435T TR 200200435 T2 TR200200435 T2 TR 200200435T2
Authority
TR
Turkey
Prior art keywords
formula
macrolide antibiotics
compounds
infections
relates
Prior art date
Application number
TR2002/00435T
Other languages
English (en)
Inventor
Kaneko Takushi
Original Assignee
Pfizer Products Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Products Inc. filed Critical Pfizer Products Inc.
Publication of TR200200435T2 publication Critical patent/TR200200435T2/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

Bu bulus, a, R1, R2, R3, R4, R5, R6 veX' ten her birinin yukarida tanimlandigi gibi oldugu formül (I)' e ait bilesiklerle, ve bunlarin, çesitli bakteriyel ve protozoal enfeksiyonlari ve bu enfeksiyonlara bagli bozukluklari tedavi etmek için kullanilabilen potansiyel antibakteriyel ve antiprotozoal maddeler olarak faydali farmasötik açidan kabul gören tuzlari ile ilgilidir. Bulus ayrica formül (I)' e ait bilesikleri ihtiva eden farmasötik kompozisyonlarla ve formül (I)' e ait bilesiklerin uygulanmasi suretiyle bakteriyel ve protozoal enfeksiyonlarin tedavi edilmesine yönelik metotlarla da ilgilidir.
TR2002/00435T 1998-11-03 1999-10-18 Yeni makrolit antibiyotikler. TR200200435T2 (tr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10683698P 1998-11-03 1998-11-03
PCT/IB1999/001701 WO2000026224A2 (en) 1998-11-03 1999-10-18 Novel macrolide antibiotics

Publications (1)

Publication Number Publication Date
TR200200435T2 true TR200200435T2 (tr) 2002-07-22

Family

ID=22313524

Family Applications (4)

Application Number Title Priority Date Filing Date
TR2001/01241T TR200101241T2 (tr) 1998-11-03 1999-10-18 Yeni makrolit antibiyotikler
TR2002/00435T TR200200435T2 (tr) 1998-11-03 1999-10-18 Yeni makrolit antibiyotikler.
TR2002/00436T TR200200436T2 (tr) 1998-11-03 1999-10-18 Yeni makrolit antibiyotikler
TR2002/00434T TR200200434T2 (tr) 1998-11-03 1999-10-18 Yeni makrolit antibiyotikler.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
TR2001/01241T TR200101241T2 (tr) 1998-11-03 1999-10-18 Yeni makrolit antibiyotikler

Family Applications After (2)

Application Number Title Priority Date Filing Date
TR2002/00436T TR200200436T2 (tr) 1998-11-03 1999-10-18 Yeni makrolit antibiyotikler
TR2002/00434T TR200200434T2 (tr) 1998-11-03 1999-10-18 Yeni makrolit antibiyotikler.

Country Status (34)

Country Link
US (3) US20020040007A1 (tr)
EP (1) EP1124837A2 (tr)
JP (1) JP4043191B2 (tr)
KR (1) KR20010083944A (tr)
CN (1) CN1376160A (tr)
AP (1) AP2001002131A0 (tr)
AU (1) AU5995299A (tr)
BG (1) BG105543A (tr)
BR (1) BR9914998A (tr)
CA (1) CA2349338C (tr)
CO (1) CO5140110A1 (tr)
CZ (1) CZ20011512A3 (tr)
EA (1) EA200100396A1 (tr)
EE (1) EE200100245A (tr)
GT (1) GT199900192A (tr)
HK (1) HK1049010A1 (tr)
HR (1) HRP20010306A2 (tr)
HU (1) HUP0104192A3 (tr)
ID (1) ID28286A (tr)
IL (1) IL142628A0 (tr)
IS (1) IS5919A (tr)
MA (1) MA26703A1 (tr)
NO (1) NO20012155L (tr)
OA (1) OA11670A (tr)
PA (1) PA8485101A1 (tr)
PE (1) PE20001289A1 (tr)
PL (1) PL348114A1 (tr)
SK (1) SK5812001A3 (tr)
SV (1) SV1999000188A (tr)
TN (1) TNSN99205A1 (tr)
TR (4) TR200101241T2 (tr)
UY (1) UY25780A1 (tr)
WO (1) WO2000026224A2 (tr)
ZA (1) ZA200103289B (tr)

Families Citing this family (24)

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Publication number Priority date Publication date Assignee Title
AP9801420A0 (en) * 1998-01-02 1998-12-31 Pfizer Prod Inc Novel macrolides.
CA2349338C (en) 1998-11-03 2005-12-06 Pfizer Products Inc. Novel macrolide antibiotics
BR9916969A (pt) 1999-01-27 2001-11-06 Pfizer Prod Inc Antibióticos cetólidos
AU4354900A (en) 1999-04-16 2000-11-02 Kosan Biosciences, Inc. Ketolide antibacterials
US6590083B1 (en) 1999-04-16 2003-07-08 Ortho-Mcneil Pharmaceutical, Inc. Ketolide antibacterials
US6451768B1 (en) 1999-04-16 2002-09-17 Kosan Biosciences, Inc. Macrolide antiinfective agents
US6939861B2 (en) 1999-04-16 2005-09-06 Kosan Biosciences, Inc. Amido macrolides
ES2272273T3 (es) 1999-04-16 2007-05-01 Kosan Biosciences, Inc. Agentes antiinfecciosos macrolidos.
US6514944B2 (en) 1999-04-16 2003-02-04 Kosan Biosciences, Inc. Macrolide antiinfective agents
WO2000071557A1 (en) 1999-05-24 2000-11-30 Pfizer Products Inc. 13-methyl-erythromycin derivatives
EP1114826A3 (en) * 1999-12-29 2001-10-31 Pfizer Products Inc. Novel antibacterial and prokinetic macrolides
EP1146051A3 (en) * 2000-04-10 2001-10-31 Pfizer Products Inc. Erythromycin A derivatives
DK1167376T3 (da) 2000-06-30 2004-10-25 Pfizer Prod Inc Makrolidantibiotika
JP2008508322A (ja) * 2004-07-28 2008-03-21 ランバクシー ラボラトリーズ リミテッド 抗菌剤としてのケトライド誘導体
WO2006046112A2 (en) * 2004-10-25 2006-05-04 Ranbaxy Laboratories Limited Ketolide derivatives as antibacterial agents
EP1836211B1 (en) * 2004-12-21 2010-03-03 Pfizer Products Inc. Macrolides
US20090130225A1 (en) * 2005-11-23 2009-05-21 Anjan Chakrabarti Macrolides derivatives as antibacterial agents
EP1957508A2 (en) * 2005-11-23 2008-08-20 Ranbaxy Laboratories Limited Ketolide derivatives as antibacterial agents
US7801502B2 (en) * 2006-12-18 2010-09-21 Aai Corporation Method for implementing continuous radio frequency (RF) alignment in advanced electronic warfare (EW) signal stimulation systems
US8409628B2 (en) 2010-02-04 2013-04-02 Penguin IP Holdings, Inc. Methods and compositions for oxygenation of skin to treat skin disorders
US8900601B2 (en) 2010-03-31 2014-12-02 Jennifer Bartels Permeable mixtures, methods and compositions for the skin
CN105358141A (zh) * 2013-05-01 2016-02-24 尼奥酷里私人有限公司 治疗细菌感染的方法
RU2537143C1 (ru) * 2013-11-08 2014-12-27 Государственное научное учреждение Ставропольский научно-исследовательский институт животноводства и кормопроизводства РАСХН Препарат для лечения и профилактики мастита у коров
WO2018080072A2 (ko) * 2016-10-27 2018-05-03 한국생명공학연구원 신규한 매크로라이드계 화합물, 이의 제조방법 및 이를 유효성분으로 함유하는 말라리아의 예방 또는 치료용 약학적 조성물

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DE69919769T2 (de) 1998-03-03 2005-01-27 Pfizer Products Inc., Groton 3,6-Ketal-Makrolidantibiotika
CA2349338C (en) 1998-11-03 2005-12-06 Pfizer Products Inc. Novel macrolide antibiotics
WO2000071557A1 (en) 1999-05-24 2000-11-30 Pfizer Products Inc. 13-methyl-erythromycin derivatives
EP1114826A3 (en) 1999-12-29 2001-10-31 Pfizer Products Inc. Novel antibacterial and prokinetic macrolides
EP1122261A3 (en) 2000-01-31 2001-09-26 Pfizer Products Inc. 13 and 14-membered antibacterial macrolides
DK1167376T3 (da) 2000-06-30 2004-10-25 Pfizer Prod Inc Makrolidantibiotika
WO2003004509A2 (en) 2001-07-03 2003-01-16 Chiron Corporation C12 modified erythromycin macrolides and ketolides having antibacterial activity

Also Published As

Publication number Publication date
CA2349338C (en) 2005-12-06
OA11670A (en) 2005-01-12
AU5995299A (en) 2000-05-22
US6835716B2 (en) 2004-12-28
BR9914998A (pt) 2001-07-10
US20030013665A1 (en) 2003-01-16
IL142628A0 (en) 2002-03-10
WO2000026224A3 (en) 2000-11-16
TR200200434T2 (tr) 2002-09-23
US7071170B2 (en) 2006-07-04
NO20012155L (no) 2001-07-02
MA26703A1 (fr) 2004-12-20
UY25780A1 (es) 2001-08-27
SV1999000188A (es) 2000-10-16
WO2000026224A2 (en) 2000-05-11
CO5140110A1 (es) 2002-03-22
HRP20010306A2 (en) 2002-06-30
US20020040007A1 (en) 2002-04-04
TR200200436T2 (tr) 2002-06-21
HUP0104192A2 (hu) 2002-02-28
GT199900192A (es) 2001-04-26
PA8485101A1 (es) 2002-08-26
TNSN99205A1 (fr) 2005-11-10
PL348114A1 (en) 2002-05-06
HK1049010A1 (zh) 2003-04-25
CN1376160A (zh) 2002-10-23
CZ20011512A3 (cs) 2001-09-12
SK5812001A3 (en) 2001-12-03
EA200100396A1 (ru) 2001-10-22
AP2001002131A0 (en) 2001-06-30
CA2349338A1 (en) 2000-05-11
PE20001289A1 (es) 2000-11-22
ZA200103289B (en) 2002-08-28
ID28286A (id) 2001-05-10
BG105543A (en) 2001-12-29
JP2002528553A (ja) 2002-09-03
JP4043191B2 (ja) 2008-02-06
KR20010083944A (ko) 2001-09-03
US20050004047A1 (en) 2005-01-06
NO20012155D0 (no) 2001-05-02
HUP0104192A3 (en) 2003-12-29
EP1124837A2 (en) 2001-08-22
TR200101241T2 (tr) 2001-09-21
EE200100245A (et) 2002-10-15
IS5919A (is) 2001-04-17

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