TR200101241T2 - Yeni makrolit antibiyotikler - Google Patents

Yeni makrolit antibiyotikler

Info

Publication number
TR200101241T2
TR200101241T2 TR2001/01241T TR200101241T TR200101241T2 TR 200101241 T2 TR200101241 T2 TR 200101241T2 TR 2001/01241 T TR2001/01241 T TR 2001/01241T TR 200101241 T TR200101241 T TR 200101241T TR 200101241 T2 TR200101241 T2 TR 200101241T2
Authority
TR
Turkey
Prior art keywords
formula
macrolide antibiotics
compounds
infections
relates
Prior art date
Application number
TR2001/01241T
Other languages
English (en)
Inventor
Kaneko Takushi
Original Assignee
Pfizer Products Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Products Inc. filed Critical Pfizer Products Inc.
Publication of TR200101241T2 publication Critical patent/TR200101241T2/tr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08Hetero rings containing eight or more ring members, e.g. erythromycins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/14Antitussive agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Pulmonology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Oncology (AREA)
  • Cardiology (AREA)
  • Communicable Diseases (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Vascular Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

Bu bulus, a, R1, R2, R3, R4, R5, R6 ve X'ten her birinin yukarida tanimlandigi gibi oldugu formül (I)'e ait bilesiklerle, ve bunlarin, çesitli bakteriyel ve protozoal enfeksiyonlari ve bu enfeksiyonlara bagli bozukluklari tedavi etmek için kullanilabilen potansiyel antibakteriyel ve antiprotozoal maddeler olarak faydali farmasötik açidan kabul gören tuzlari ile ilgilidir. Bulus ayrica formül (I)'e ait bilesikleri ihtiva eden farmasötik kompozisyonlarla ve formül (I)'e ait bilesiklerin uygulanmasi suretiyle bakteriyel ve protozoal enfeksiyonlarin tedavi edilmesine yönelik metotlarla da ilgilidir.
TR2001/01241T 1998-11-03 1999-10-18 Yeni makrolit antibiyotikler TR200101241T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10683698P 1998-11-03 1998-11-03

Publications (1)

Publication Number Publication Date
TR200101241T2 true TR200101241T2 (tr) 2001-09-21

Family

ID=22313524

Family Applications (4)

Application Number Title Priority Date Filing Date
TR2002/00436T TR200200436T2 (tr) 1998-11-03 1999-10-18 Yeni makrolit antibiyotikler
TR2002/00435T TR200200435T2 (tr) 1998-11-03 1999-10-18 Yeni makrolit antibiyotikler.
TR2002/00434T TR200200434T2 (tr) 1998-11-03 1999-10-18 Yeni makrolit antibiyotikler.
TR2001/01241T TR200101241T2 (tr) 1998-11-03 1999-10-18 Yeni makrolit antibiyotikler

Family Applications Before (3)

Application Number Title Priority Date Filing Date
TR2002/00436T TR200200436T2 (tr) 1998-11-03 1999-10-18 Yeni makrolit antibiyotikler
TR2002/00435T TR200200435T2 (tr) 1998-11-03 1999-10-18 Yeni makrolit antibiyotikler.
TR2002/00434T TR200200434T2 (tr) 1998-11-03 1999-10-18 Yeni makrolit antibiyotikler.

Country Status (34)

Country Link
US (3) US20020040007A1 (tr)
EP (1) EP1124837A2 (tr)
JP (1) JP4043191B2 (tr)
KR (1) KR20010083944A (tr)
CN (1) CN1376160A (tr)
AP (1) AP2001002131A0 (tr)
AU (1) AU5995299A (tr)
BG (1) BG105543A (tr)
BR (1) BR9914998A (tr)
CA (1) CA2349338C (tr)
CO (1) CO5140110A1 (tr)
CZ (1) CZ20011512A3 (tr)
EA (1) EA200100396A1 (tr)
EE (1) EE200100245A (tr)
GT (1) GT199900192A (tr)
HK (1) HK1049010A1 (tr)
HR (1) HRP20010306A2 (tr)
HU (1) HUP0104192A3 (tr)
ID (1) ID28286A (tr)
IL (1) IL142628A0 (tr)
IS (1) IS5919A (tr)
MA (1) MA26703A1 (tr)
NO (1) NO20012155L (tr)
OA (1) OA11670A (tr)
PA (1) PA8485101A1 (tr)
PE (1) PE20001289A1 (tr)
PL (1) PL348114A1 (tr)
SK (1) SK5812001A3 (tr)
SV (1) SV1999000188A (tr)
TN (1) TNSN99205A1 (tr)
TR (4) TR200200436T2 (tr)
UY (1) UY25780A1 (tr)
WO (1) WO2000026224A2 (tr)
ZA (1) ZA200103289B (tr)

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AP9801420A0 (en) * 1998-01-02 1998-12-31 Pfizer Prod Inc Novel macrolides.
HUP0104192A3 (en) 1998-11-03 2003-12-29 Pfizer Prod Inc Novel macrolide antibiotics
BR9916969A (pt) 1999-01-27 2001-11-06 Pfizer Prod Inc Antibióticos cetólidos
US6451768B1 (en) 1999-04-16 2002-09-17 Kosan Biosciences, Inc. Macrolide antiinfective agents
US6590083B1 (en) 1999-04-16 2003-07-08 Ortho-Mcneil Pharmaceutical, Inc. Ketolide antibacterials
US6939861B2 (en) 1999-04-16 2005-09-06 Kosan Biosciences, Inc. Amido macrolides
US6514944B2 (en) 1999-04-16 2003-02-04 Kosan Biosciences, Inc. Macrolide antiinfective agents
US6458771B1 (en) 1999-04-16 2002-10-01 Ortho-Mcneil Pharmaceutical, Inc. Ketolide antibacterials
WO2000063224A2 (en) 1999-04-16 2000-10-26 Kosan Biosciences, Inc. Macrolide antiinfective agents
IL145739A0 (en) 1999-05-24 2002-07-25 Pfizer Prod Inc 13-methyl-erythromycin derivatives
EP1114826A3 (en) * 1999-12-29 2001-10-31 Pfizer Products Inc. Novel antibacterial and prokinetic macrolides
EP1146051A3 (en) * 2000-04-10 2001-10-31 Pfizer Products Inc. Erythromycin A derivatives
DE60104240T2 (de) 2000-06-30 2005-08-04 Pfizer Products Inc., Groton Makrolid-Antibiotika
JP2008508322A (ja) * 2004-07-28 2008-03-21 ランバクシー ラボラトリーズ リミテッド 抗菌剤としてのケトライド誘導体
EP1807439A2 (en) * 2004-10-25 2007-07-18 Ranbaxy Laboratories Limited Ketolide derivatives as antibacterial agents
EA011281B1 (ru) * 2004-12-21 2009-02-27 Пфайзер Продактс Инк. Макролиды
US20090005325A1 (en) * 2005-11-23 2009-01-01 Biswajit Bas Ketolide Derivatives as Antibacterial Agents
WO2007060618A2 (en) * 2005-11-23 2007-05-31 Ranbaxy Laboratories Limited Macrolides derivatives as antibacterial agents
US7801502B2 (en) * 2006-12-18 2010-09-21 Aai Corporation Method for implementing continuous radio frequency (RF) alignment in advanced electronic warfare (EW) signal stimulation systems
US8409628B2 (en) 2010-02-04 2013-04-02 Penguin IP Holdings, Inc. Methods and compositions for oxygenation of skin to treat skin disorders
WO2011123619A2 (en) 2010-03-31 2011-10-06 Penguin Ip Holdings Inc. Permeable mixtures, methods and compositions for the skin
US9539223B2 (en) * 2013-05-01 2017-01-10 Neoculi Pty Ltd Methods for treating bacterial infections
RU2537143C1 (ru) * 2013-11-08 2014-12-27 Государственное научное учреждение Ставропольский научно-исследовательский институт животноводства и кормопроизводства РАСХН Препарат для лечения и профилактики мастита у коров
WO2018080072A2 (ko) * 2016-10-27 2018-05-03 한국생명공학연구원 신규한 매크로라이드계 화합물, 이의 제조방법 및 이를 유효성분으로 함유하는 말라리아의 예방 또는 치료용 약학적 조성물

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HUP0104192A3 (en) 1998-11-03 2003-12-29 Pfizer Prod Inc Novel macrolide antibiotics
IL145739A0 (en) 1999-05-24 2002-07-25 Pfizer Prod Inc 13-methyl-erythromycin derivatives
EP1114826A3 (en) 1999-12-29 2001-10-31 Pfizer Products Inc. Novel antibacterial and prokinetic macrolides
EP1122261A3 (en) 2000-01-31 2001-09-26 Pfizer Products Inc. 13 and 14-membered antibacterial macrolides
DE60104240T2 (de) 2000-06-30 2005-08-04 Pfizer Products Inc., Groton Makrolid-Antibiotika
CA2451391A1 (en) 2001-07-03 2003-01-16 Chiron Corporation C12 modified erythromycin macrolides and ketolides having antibacterial activity

Also Published As

Publication number Publication date
CN1376160A (zh) 2002-10-23
OA11670A (en) 2005-01-12
TR200200434T2 (tr) 2002-09-23
TR200200435T2 (tr) 2002-07-22
SK5812001A3 (en) 2001-12-03
PA8485101A1 (es) 2002-08-26
EA200100396A1 (ru) 2001-10-22
US20020040007A1 (en) 2002-04-04
CA2349338A1 (en) 2000-05-11
BR9914998A (pt) 2001-07-10
WO2000026224A3 (en) 2000-11-16
IL142628A0 (en) 2002-03-10
ZA200103289B (en) 2002-08-28
HUP0104192A2 (hu) 2002-02-28
PE20001289A1 (es) 2000-11-22
MA26703A1 (fr) 2004-12-20
ID28286A (id) 2001-05-10
SV1999000188A (es) 2000-10-16
JP4043191B2 (ja) 2008-02-06
CZ20011512A3 (cs) 2001-09-12
US7071170B2 (en) 2006-07-04
CA2349338C (en) 2005-12-06
US6835716B2 (en) 2004-12-28
PL348114A1 (en) 2002-05-06
NO20012155D0 (no) 2001-05-02
TR200200436T2 (tr) 2002-06-21
AU5995299A (en) 2000-05-22
IS5919A (is) 2001-04-17
KR20010083944A (ko) 2001-09-03
EP1124837A2 (en) 2001-08-22
HUP0104192A3 (en) 2003-12-29
JP2002528553A (ja) 2002-09-03
TNSN99205A1 (fr) 2005-11-10
CO5140110A1 (es) 2002-03-22
WO2000026224A2 (en) 2000-05-11
HK1049010A1 (zh) 2003-04-25
GT199900192A (es) 2001-04-26
UY25780A1 (es) 2001-08-27
NO20012155L (no) 2001-07-02
AP2001002131A0 (en) 2001-06-30
US20050004047A1 (en) 2005-01-06
US20030013665A1 (en) 2003-01-16
BG105543A (en) 2001-12-29
EE200100245A (et) 2002-10-15
HRP20010306A2 (en) 2002-06-30

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