TR200102801T2 - Solid tümörlerin tedavisine yönelik yöntem ve bileşimler - Google Patents
Solid tümörlerin tedavisine yönelik yöntem ve bileşimlerInfo
- Publication number
- TR200102801T2 TR200102801T2 TR2001/02801T TR200102801T TR200102801T2 TR 200102801 T2 TR200102801 T2 TR 200102801T2 TR 2001/02801 T TR2001/02801 T TR 2001/02801T TR 200102801 T TR200102801 T TR 200102801T TR 200102801 T2 TR200102801 T2 TR 200102801T2
- Authority
- TR
- Turkey
- Prior art keywords
- compositions
- treatment
- methods
- solid tumors
- tumor
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title abstract 4
- 239000000203 mixture Substances 0.000 title abstract 2
- 241000124008 Mammalia Species 0.000 abstract 1
- 229940034982 antineoplastic agent Drugs 0.000 abstract 1
- 239000002246 antineoplastic agent Substances 0.000 abstract 1
- 229920002988 biodegradable polymer Polymers 0.000 abstract 1
- 239000004621 biodegradable polymer Substances 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
- A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Inorganic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Materials For Medical Uses (AREA)
- Compositions Of Macromolecular Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/276,866 US6537585B1 (en) | 1999-03-26 | 1999-03-26 | Methods and compositions for treating solid tumors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TR200102801T2 true TR200102801T2 (tr) | 2002-04-22 |
Family
ID=23058398
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR2001/02801T TR200102801T2 (tr) | 1999-03-26 | 2000-03-20 | Solid tümörlerin tedavisine yönelik yöntem ve bileşimler |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US6537585B1 (https=) |
| EP (1) | EP1185249B1 (https=) |
| JP (2) | JP2002540137A (https=) |
| KR (1) | KR20010111578A (https=) |
| CN (1) | CN1367684A (https=) |
| AT (1) | ATE306251T1 (https=) |
| AU (1) | AU778279B2 (https=) |
| BR (1) | BR0009213A (https=) |
| CA (1) | CA2368621C (https=) |
| CZ (1) | CZ20013260A3 (https=) |
| DE (1) | DE60023138T2 (https=) |
| HU (1) | HUP0201436A3 (https=) |
| IL (1) | IL145492A0 (https=) |
| NO (1) | NO20014662L (https=) |
| PL (1) | PL351280A1 (https=) |
| TR (1) | TR200102801T2 (https=) |
| WO (1) | WO2000057852A2 (https=) |
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|---|---|---|---|---|
| US6350464B1 (en) * | 1999-01-11 | 2002-02-26 | Guilford Pharmaceuticals, Inc. | Methods for treating ovarian cancer, poly (phosphoester) compositions, and biodegradable articles for same |
| US6537585B1 (en) | 1999-03-26 | 2003-03-25 | Guilford Pharmaceuticals, Inc. | Methods and compositions for treating solid tumors |
| AU2001270310A1 (en) * | 2000-07-07 | 2002-01-21 | Guilford Pharmaceuticals Inc. | Compositions for sustained release of antineoplastic taxanes, and methods of making and using the same |
| AU2001280597A1 (en) * | 2000-07-17 | 2002-01-30 | Guilford Pharmaceuticals Inc. | Compositions for sustained release of analgesic agents, and methods of making and using the same |
| US20020198135A1 (en) * | 2000-10-12 | 2002-12-26 | Wenbin Dang | Compositions for release of radiosensitizers, and methods of making and using the same |
| US20020141966A1 (en) * | 2000-11-16 | 2002-10-03 | Wenbin Dang | Compositions for treatment of malignant effusions, and methods of making and using the same |
| US20020081339A1 (en) * | 2000-12-22 | 2002-06-27 | Philippe Menei | Treatment of inoperable tumors by stereotactic injection of microspheres |
| WO2003000776A1 (en) * | 2001-05-14 | 2003-01-03 | Johns Hopkins Singapore Pte Ltd | Biodegradable polyphosphoramidates for controlled release of bioactive substances |
| US7345138B2 (en) * | 2001-05-14 | 2008-03-18 | Johns Hopkins Singapore Pte Ltd. | Biodegradable polyphosphates for controlled release of bioactive substances |
| WO2003007914A2 (en) * | 2001-07-19 | 2003-01-30 | Guilford Pharmaceuticals, Inc. | Biocompatible polymer containing composition for treatment of prostate cancers |
| US20030134892A1 (en) * | 2001-07-19 | 2003-07-17 | Wenbin Dang | Compositions for treatment of head and neck cancers, and methods of making and using the same |
| AU2003202255A1 (en) * | 2002-01-09 | 2003-07-30 | Guilford Pharmaceuticals, Inc. | Compositions for treatment of central nervous system neoplasms, and methods of making and using the same |
| AU2003216424A1 (en) | 2002-02-25 | 2003-10-08 | Guilford Pharmaceuticals, Inc. | Phosphorus-containing compounds with polymeric chains, and methods of making and using the same |
| GB0223379D0 (en) * | 2002-10-09 | 2002-11-13 | Angiogene Pharm Ltd | Combination therapy |
| SI1677828T1 (sl) * | 2003-10-21 | 2013-04-30 | Psimedica Limited | Kompozitni material, ki vsebuje porozen polprevodnik impregniran z organsko substanco |
| US7795205B2 (en) * | 2004-04-12 | 2010-09-14 | Canyon Pharmaceuticals, Inc. | Methods for effecting regression of tumor mass and size in a metastasized pancreatic tumor |
| WO2006002366A2 (en) * | 2004-06-24 | 2006-01-05 | Surmodics, Inc. | Biodegradable ocular devices, methods and systems |
| WO2006002399A2 (en) * | 2004-06-24 | 2006-01-05 | Surmodics, Inc. | Biodegradable implantable medical devices, methods and systems |
| US20080124400A1 (en) * | 2004-06-24 | 2008-05-29 | Angiotech International Ag | Microparticles With High Loadings Of A Bioactive Agent |
| EP1835931A4 (en) * | 2004-12-06 | 2008-12-17 | Sciclone Pharmaceuticals Inc | ALPHA THYMOSINE PEPTIDES AS CANCER VACCINE ADJUVANTIES |
| SI1853250T1 (sl) | 2005-02-18 | 2012-01-31 | Abraxis Bioscience Llc | Kombinacije in reĹľimi dajanja terapevtskih sredstev in kombinirana terapija |
| US8735394B2 (en) * | 2005-02-18 | 2014-05-27 | Abraxis Bioscience, Llc | Combinations and modes of administration of therapeutic agents and combination therapy |
| CA2618807C (en) * | 2005-08-12 | 2015-01-06 | University Health Network | Methods and devices for lymphatic targeting |
| GB0525864D0 (en) * | 2005-12-20 | 2006-02-01 | Novartis Ag | Organic compounds |
| EP3047860B1 (en) | 2006-07-20 | 2024-08-28 | OrbusNeich Medical Pte. Ltd. | Bioabsorbable polymeric composition for a medical device |
| US7959942B2 (en) | 2006-10-20 | 2011-06-14 | Orbusneich Medical, Inc. | Bioabsorbable medical device with coating |
| US8691321B2 (en) | 2006-10-20 | 2014-04-08 | Orbusneich Medical, Inc. | Bioabsorbable polymeric composition and medical device background |
| CN101390828B (zh) * | 2007-02-12 | 2010-06-09 | 济南康泉医药科技有限公司 | 同载抗代谢类药物和增效剂的抗癌组合物 |
| US11020363B2 (en) | 2009-05-29 | 2021-06-01 | Cydex Pharmaceuticals, Inc. | Injectable nitrogen mustard compositions comprising a cyclodextrin derivative and methods of making and using the same |
| CA2763365C (en) | 2009-05-29 | 2016-09-13 | Cydex Pharmaceuticals, Inc. | Injectable melphalan compositions comprising a cyclodextrin derivative and methods of making and using the same |
| ES2362525B8 (es) | 2009-10-08 | 2013-01-03 | Azurebio, S.L. | Formulación de medicamentos en forma de agujas percutaneas penetrantes. |
| TWI438009B (zh) * | 2010-02-19 | 2014-05-21 | Teikoku Pharma Usa Inc | 紫杉烷前-乳劑調配物及其製造與使用之方法 |
| NZ717490A (en) | 2010-03-29 | 2017-12-22 | Abraxis Bioscience Llc | Methods of treating cancer |
| KR20130028727A (ko) | 2010-03-29 | 2013-03-19 | 아브락시스 바이오사이언스, 엘엘씨 | 치료제의 약물 전달 및 유효성 향상 방법 |
| EA027666B1 (ru) | 2010-05-03 | 2017-08-31 | ТЕИКОКУ ФАРМА ЮСЭй, ИНК. | Неводные лекарственные средства в форме проэмульсии на основе таксанов и способы их приготовления и использования |
| BR112012030909A2 (pt) | 2010-06-04 | 2020-08-18 | Abraxis Bioscience, Llc | métodos de tratamento de câncer pancreático |
| CN104884065B (zh) | 2012-09-21 | 2019-01-01 | 强烈治疗剂公司 | 治疗癌症的方法 |
| JO3685B1 (ar) | 2012-10-01 | 2020-08-27 | Teikoku Pharma Usa Inc | صيغ التشتيت الجسيمي للتاكسين غير المائي وطرق استخدامها |
| US9545447B2 (en) | 2013-01-04 | 2017-01-17 | The Texas A&M University System | Polymer-drug systems |
| EP3302423B1 (en) | 2015-06-04 | 2022-05-25 | Crititech, Inc. | Particle production system and particle collection device |
| BR112018069628A2 (pt) | 2016-04-04 | 2019-02-12 | Crititech, Inc. | métodos para tratamento de tumor sólido |
| EP3615145B1 (en) | 2017-06-09 | 2024-05-15 | Crititech, Inc. | Compositions for use in the treatment of epithelial cysts by intracystic injection of antineoplastic particles |
| WO2018231908A1 (en) | 2017-06-14 | 2018-12-20 | Crititech, Inc. | Methods for treating lung disorders |
| KR20250057947A (ko) | 2017-10-03 | 2025-04-29 | 크리티테크, 인크. | 암의 치료를 위한 면역치료제의 전신 전달과 조합된 항신생물성 입자의 국소 전달 |
| WO2020072090A1 (en) * | 2018-10-03 | 2020-04-09 | Crititech, Inc. | Use of antineoplastic agents to stimulate the immune system for production of tertiary lymphoid structures (tls) |
| JP2022508807A (ja) | 2018-10-16 | 2022-01-19 | ユーエス・ナノ・フード・アンド・ドラッグ・インコーポレーテッド | 腫瘍内注射製剤 |
| US11752165B2 (en) | 2020-04-13 | 2023-09-12 | US Nano Food & Drug, Inc | Basic chemotherapeutic intratumour injection formulation |
| GB2623319A (en) | 2022-10-11 | 2024-04-17 | Af Chempharm Ltd | Method of synthesis of chloro-oxo-dioxaphospholane oxides and derivates |
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| US3271329A (en) | 1958-09-19 | 1966-09-06 | Eastman Kodak Co | Method for producing polymers derived from phosphites and glycols |
| US3442982A (en) | 1965-10-15 | 1969-05-06 | Weston Chemical Corp | Polyphosphites of 2,2-dimethyl-3-hydroxypropyl - 2 - dimethyl - 3-hydroxypropionate |
| FR2219193B1 (https=) | 1973-02-28 | 1976-05-21 | Rhone Poulenc Sa | |
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| DE2925206A1 (de) | 1979-06-22 | 1981-01-29 | Bayer Ag | Aromatische polyesterphosphonate, verfahren zu ihrer herstellung und ihre verwendung zur herstellung thermoplastischer formkoerper |
| FR2498612A1 (fr) | 1981-01-26 | 1982-07-30 | Peters Ligatures | Nouveaux polymeres insolubles a biodegradabilite reglable a volonte, leurs procedes de preparation et leur application en tant que biomateriaux |
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| US6350464B1 (en) | 1999-01-11 | 2002-02-26 | Guilford Pharmaceuticals, Inc. | Methods for treating ovarian cancer, poly (phosphoester) compositions, and biodegradable articles for same |
| US6537585B1 (en) | 1999-03-26 | 2003-03-25 | Guilford Pharmaceuticals, Inc. | Methods and compositions for treating solid tumors |
| CA2369740A1 (en) | 1999-04-22 | 2000-11-02 | American Biosciences, Inc. | Long term administration of pharmacologically active agents |
| AU2001270310A1 (en) | 2000-07-07 | 2002-01-21 | Guilford Pharmaceuticals Inc. | Compositions for sustained release of antineoplastic taxanes, and methods of making and using the same |
| AU2001280597A1 (en) * | 2000-07-17 | 2002-01-30 | Guilford Pharmaceuticals Inc. | Compositions for sustained release of analgesic agents, and methods of making and using the same |
| US20020198135A1 (en) * | 2000-10-12 | 2002-12-26 | Wenbin Dang | Compositions for release of radiosensitizers, and methods of making and using the same |
| WO2003007914A2 (en) * | 2001-07-19 | 2003-01-30 | Guilford Pharmaceuticals, Inc. | Biocompatible polymer containing composition for treatment of prostate cancers |
| US20030134892A1 (en) * | 2001-07-19 | 2003-07-17 | Wenbin Dang | Compositions for treatment of head and neck cancers, and methods of making and using the same |
-
1999
- 1999-03-26 US US09/276,866 patent/US6537585B1/en not_active Expired - Fee Related
-
2000
- 2000-03-20 AU AU37625/00A patent/AU778279B2/en not_active Ceased
- 2000-03-20 CA CA2368621A patent/CA2368621C/en not_active Expired - Fee Related
- 2000-03-20 IL IL14549200A patent/IL145492A0/xx unknown
- 2000-03-20 WO PCT/US2000/007304 patent/WO2000057852A2/en not_active Ceased
- 2000-03-20 CZ CZ20013260A patent/CZ20013260A3/cs unknown
- 2000-03-20 JP JP2000607603A patent/JP2002540137A/ja active Pending
- 2000-03-20 EP EP00916536A patent/EP1185249B1/en not_active Expired - Lifetime
- 2000-03-20 TR TR2001/02801T patent/TR200102801T2/xx unknown
- 2000-03-20 HU HU0201436A patent/HUP0201436A3/hu unknown
- 2000-03-20 CN CN00806972A patent/CN1367684A/zh active Pending
- 2000-03-20 AT AT00916536T patent/ATE306251T1/de not_active IP Right Cessation
- 2000-03-20 BR BR0009213-4A patent/BR0009213A/pt not_active Application Discontinuation
- 2000-03-20 DE DE60023138T patent/DE60023138T2/de not_active Expired - Lifetime
- 2000-03-20 PL PL00351280A patent/PL351280A1/xx not_active Application Discontinuation
- 2000-03-20 KR KR1020017012256A patent/KR20010111578A/ko not_active Withdrawn
-
2001
- 2001-09-25 NO NO20014662A patent/NO20014662L/no not_active Application Discontinuation
-
2003
- 2003-02-03 US US10/357,292 patent/US7101568B2/en not_active Expired - Fee Related
-
2011
- 2011-06-15 JP JP2011132938A patent/JP2011219483A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AU3762500A (en) | 2000-10-16 |
| BR0009213A (pt) | 2002-04-16 |
| CN1367684A (zh) | 2002-09-04 |
| US7101568B2 (en) | 2006-09-05 |
| NO20014662D0 (no) | 2001-09-25 |
| DE60023138D1 (de) | 2006-02-23 |
| PL351280A1 (en) | 2003-04-07 |
| CA2368621A1 (en) | 2000-10-05 |
| US6537585B1 (en) | 2003-03-25 |
| US20030203033A1 (en) | 2003-10-30 |
| WO2000057852A2 (en) | 2000-10-05 |
| ATE306251T1 (de) | 2005-10-15 |
| CZ20013260A3 (cs) | 2002-01-16 |
| KR20010111578A (ko) | 2001-12-19 |
| HUP0201436A2 (en) | 2002-09-28 |
| CA2368621C (en) | 2010-05-25 |
| DE60023138T2 (de) | 2006-08-17 |
| IL145492A0 (en) | 2002-06-30 |
| AU778279B2 (en) | 2004-11-25 |
| EP1185249B1 (en) | 2005-10-12 |
| JP2011219483A (ja) | 2011-11-04 |
| NO20014662L (no) | 2001-11-20 |
| HUP0201436A3 (en) | 2003-04-28 |
| WO2000057852A3 (en) | 2001-02-15 |
| EP1185249A2 (en) | 2002-03-13 |
| JP2002540137A (ja) | 2002-11-26 |
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