TR200102012T2 - Yumurtalık kanserinin tedavi yöntemleri, poli (fosfoester) bileşimler ile bunlara ait biyolojik olarak parçalanabilir maddeler. - Google Patents
Yumurtalık kanserinin tedavi yöntemleri, poli (fosfoester) bileşimler ile bunlara ait biyolojik olarak parçalanabilir maddeler.Info
- Publication number
- TR200102012T2 TR200102012T2 TR2001/02012T TR200102012T TR200102012T2 TR 200102012 T2 TR200102012 T2 TR 200102012T2 TR 2001/02012 T TR2001/02012 T TR 2001/02012T TR 200102012 T TR200102012 T TR 200102012T TR 200102012 T2 TR200102012 T2 TR 200102012T2
- Authority
- TR
- Turkey
- Prior art keywords
- experiment
- phosphoester
- ovarian cancer
- antineoplastic agent
- poly
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 4
- 206010033128 Ovarian cancer Diseases 0.000 title abstract 2
- 206010061535 Ovarian neoplasm Diseases 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 239000000126 substance Substances 0.000 title abstract 2
- 229940034982 antineoplastic agent Drugs 0.000 abstract 4
- 239000002246 antineoplastic agent Substances 0.000 abstract 4
- 229920000642 polymer Polymers 0.000 abstract 3
- 229920002988 biodegradable polymer Polymers 0.000 abstract 2
- 239000004621 biodegradable polymer Substances 0.000 abstract 2
- 241000124008 Mammalia Species 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000011534 incubation Methods 0.000 abstract 1
- 210000004303 peritoneum Anatomy 0.000 abstract 1
- 230000004083 survival effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
- A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7007—Drug-containing films, membranes or sheets
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/902—Specified use of nanostructure
- Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
- Y10S977/908—Mechanical repair performed/surgical
- Y10S977/911—Cancer cell destruction
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/902—Specified use of nanostructure
- Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
- Y10S977/908—Mechanical repair performed/surgical
- Y10S977/912—Cancer cell repair
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Biological Depolymerization Polymers (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Yumurtalik kanseri memeli deneyin tedavisinde pertion içine verilmeye elverisli biyolojik olarak parçalanabilir polimer bilesimleri açiklanmaktadir. Bilesim (a) en azindan bir antineoplastik ajan ile (b) biyolojik olarak parçalanabilir bir fosfoester polimeri ihtiva eder. Burada polimer bilesimi antineoplastik ajanin deneyin peritonu içine uzatilmis süre ile verilebilmesini saglar. Deneye antineoplastik ajanla birlikte verilen polimer bilesimi, ayni dozaja sahip ancak bulusa konu biyolojik olarak parçalanabilir polimer olmaksizin deneye verilen antineoplastik ajanin sagladigi hayatta kalma oranini en azindan %10 arttirmaktadir. Yumurtalik kanserinin tedavisiyle ilgili kati madde ve yöntemler de tariflenmektedir.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/227,852 US6350464B1 (en) | 1999-01-11 | 1999-01-11 | Methods for treating ovarian cancer, poly (phosphoester) compositions, and biodegradable articles for same |
Publications (1)
Publication Number | Publication Date |
---|---|
TR200102012T2 true TR200102012T2 (tr) | 2002-01-21 |
Family
ID=22854735
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR2001/02012T TR200102012T2 (tr) | 1999-01-11 | 1999-12-23 | Yumurtalık kanserinin tedavi yöntemleri, poli (fosfoester) bileşimler ile bunlara ait biyolojik olarak parçalanabilir maddeler. |
Country Status (20)
Country | Link |
---|---|
US (4) | US6350464B1 (tr) |
EP (1) | EP1140028B1 (tr) |
JP (1) | JP2002534456A (tr) |
KR (1) | KR20010101472A (tr) |
CN (1) | CN1337878A (tr) |
AT (1) | ATE310506T1 (tr) |
AU (1) | AU779182B2 (tr) |
BR (1) | BR9916881A (tr) |
CA (1) | CA2359109C (tr) |
CZ (1) | CZ20012416A3 (tr) |
DE (1) | DE69928567T2 (tr) |
HU (1) | HUP0202670A3 (tr) |
IL (2) | IL145087A0 (tr) |
IN (1) | IN2001CH01053A (tr) |
MX (1) | MX236541B (tr) |
NO (1) | NO20013402L (tr) |
RU (1) | RU2001122708A (tr) |
TR (1) | TR200102012T2 (tr) |
WO (1) | WO2000041678A1 (tr) |
ZA (1) | ZA200106499B (tr) |
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US6537585B1 (en) * | 1999-03-26 | 2003-03-25 | Guilford Pharmaceuticals, Inc. | Methods and compositions for treating solid tumors |
AU6536400A (en) * | 1999-08-11 | 2001-03-05 | Alkermes Controlled Therapeutics, Inc. | Method of delivering a chemotherapeutic agent to a solid tumor |
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WO2002005800A2 (en) * | 2000-07-17 | 2002-01-24 | Guilford Pharmaceuticals, Inc. | Compositions for sustained release of analgesic agents, and methods of making and using the same |
AU2001296800A1 (en) * | 2000-10-06 | 2002-04-15 | Johns Hopkins University | Systemic delivery of compounds through non-invasive bladder administration |
AU2002215333A1 (en) * | 2000-10-12 | 2002-04-22 | Guilford Pharmaceuticals Inc. | Compositions for release of radiosensitizers, and methods of making and using the same |
US20020141966A1 (en) * | 2000-11-16 | 2002-10-03 | Wenbin Dang | Compositions for treatment of malignant effusions, and methods of making and using the same |
US20030133903A1 (en) * | 2001-07-19 | 2003-07-17 | Wenbin Dang | Compositions for treatment of prostate cancers and methods of making and using the same |
WO2003007915A2 (en) * | 2001-07-19 | 2003-01-30 | Guilford Pharmaceuticals, Inc. | Compositions for treatment of head and neck cancers, and methods of making and using the same |
WO2003060799A2 (en) * | 2002-01-09 | 2003-07-24 | Guilford Pharmaceuticals, Inc. | Compositions for treatment of central nervous system neoplasms, and methods of making and using the same |
ITMI20020680A1 (it) * | 2002-03-29 | 2003-09-29 | Acs Dobfar Spa | Composizione antitumorale migliorata a base di paclitaxel e metodo per il suo ottenimento |
US20050244402A1 (en) * | 2004-04-30 | 2005-11-03 | Villanueva Julie M | Absorption of pain-causing agents |
US20080124400A1 (en) * | 2004-06-24 | 2008-05-29 | Angiotech International Ag | Microparticles With High Loadings Of A Bioactive Agent |
US7871573B2 (en) * | 2004-07-26 | 2011-01-18 | University Of Louisville Research Foundation, Inc. | Enhancement of sensitivity of fluorophore mediated biosensing and bioimaging |
US8563328B2 (en) * | 2004-07-26 | 2013-10-22 | University Of Louisville Research Foundation, Inc. | Fiber-optic biosensor and biosensing methods |
US7517914B2 (en) * | 2005-04-04 | 2009-04-14 | Boston Scientificscimed, Inc. | Controlled degradation materials for therapeutic agent delivery |
US8580814B2 (en) * | 2006-04-03 | 2013-11-12 | Sunesis Pharmaceuticals, Inc. | Methods of using (+)-1,4-dihydro-7-[(3S,4S)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4- oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid for treatment of cancer |
GB0525864D0 (en) * | 2005-12-20 | 2006-02-01 | Novartis Ag | Organic compounds |
EP3061791B1 (en) | 2006-07-20 | 2019-01-16 | OrbusNeich Medical, Inc. | Bioabsorbable polymeric composition for a medical device |
US20090169628A1 (en) | 2006-10-17 | 2009-07-02 | Armark Authentication Technologies, Llc | Article and method for focused delivery of therapeutic and/or diagnostic materials |
US7959942B2 (en) | 2006-10-20 | 2011-06-14 | Orbusneich Medical, Inc. | Bioabsorbable medical device with coating |
CN101631513B (zh) | 2006-10-20 | 2013-06-05 | 奥巴斯尼茨医学公司 | 可生物吸收的聚合物组合物和医疗设备 |
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CA2708514A1 (en) * | 2007-12-31 | 2009-07-16 | Armark Authentication Technologies, Llc | Article and method for focused delivery of therapeutic and/or diagnostic materials |
WO2010037021A2 (en) * | 2008-09-29 | 2010-04-01 | Armark Authentication Technologies, Llc | Spinneret and method of spinning fiber |
US20100291214A1 (en) * | 2008-12-23 | 2010-11-18 | Armark Authentication Technologies, Llc | Three-dimensional microfiber extrudate structure and process for forming three-dimensional microfiber extrudate structure |
WO2010132763A1 (en) * | 2009-05-15 | 2010-11-18 | Armark Authentication Technologies, Llc | Fiber having non-uniform composition and method for making same |
CN103917224A (zh) * | 2011-07-19 | 2014-07-09 | Stc·Unm公司 | 基于在癌症的炎症环境释放治疗性负载的腹膜内给药的纳米载体 |
US10058688B2 (en) * | 2012-05-09 | 2018-08-28 | Massachusetts Institute Of Technology | Medicament, method, and drug delivery device for treatment of ovarian cancer |
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-
1999
- 1999-01-11 US US09/227,852 patent/US6350464B1/en not_active Expired - Fee Related
- 1999-02-25 IL IL14508799A patent/IL145087A0/xx unknown
- 1999-12-23 AT AT99964321T patent/ATE310506T1/de not_active IP Right Cessation
- 1999-12-23 DE DE69928567T patent/DE69928567T2/de not_active Expired - Lifetime
- 1999-12-23 CA CA2359109A patent/CA2359109C/en not_active Expired - Fee Related
- 1999-12-23 TR TR2001/02012T patent/TR200102012T2/tr unknown
- 1999-12-23 CZ CZ20012416A patent/CZ20012416A3/cs unknown
- 1999-12-23 IL IL14408799A patent/IL144087A0/xx unknown
- 1999-12-23 EP EP99964321A patent/EP1140028B1/en not_active Expired - Lifetime
- 1999-12-23 BR BR9916881-2A patent/BR9916881A/pt not_active Application Discontinuation
- 1999-12-23 AU AU20591/00A patent/AU779182B2/en not_active Expired - Fee Related
- 1999-12-23 KR KR1020017008774A patent/KR20010101472A/ko not_active Application Discontinuation
- 1999-12-23 CN CN99816287A patent/CN1337878A/zh active Pending
- 1999-12-23 MX MXPA01007018 patent/MX236541B/es not_active IP Right Cessation
- 1999-12-23 WO PCT/US1999/030814 patent/WO2000041678A1/en active IP Right Grant
- 1999-12-23 HU HU0202670A patent/HUP0202670A3/hu unknown
- 1999-12-23 JP JP2000593290A patent/JP2002534456A/ja active Pending
- 1999-12-23 RU RU2001122708/15A patent/RU2001122708A/ru unknown
-
2001
- 2001-03-28 US US09/819,376 patent/US6479067B2/en not_active Expired - Fee Related
- 2001-07-09 NO NO20013402A patent/NO20013402L/no not_active Application Discontinuation
- 2001-07-25 IN IN1053CH2001 patent/IN2001CH01053A/xx unknown
- 2001-08-07 ZA ZA200106499A patent/ZA200106499B/xx unknown
-
2002
- 2002-10-04 US US10/264,793 patent/US6641833B2/en not_active Expired - Fee Related
-
2003
- 2003-08-14 US US10/641,301 patent/US20040071774A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US20040071774A1 (en) | 2004-04-15 |
MX236541B (es) | 2006-05-04 |
AU779182B2 (en) | 2005-01-13 |
JP2002534456A (ja) | 2002-10-15 |
CZ20012416A3 (cs) | 2001-11-14 |
CA2359109A1 (en) | 2000-07-20 |
KR20010101472A (ko) | 2001-11-14 |
US20030138493A1 (en) | 2003-07-24 |
EP1140028B1 (en) | 2005-11-23 |
DE69928567T2 (de) | 2006-08-17 |
US6479067B2 (en) | 2002-11-12 |
US6641833B2 (en) | 2003-11-04 |
IL144087A0 (en) | 2002-05-23 |
IN2001CH01053A (en) | 2005-03-04 |
HUP0202670A3 (en) | 2003-02-28 |
NO20013402D0 (no) | 2001-07-09 |
BR9916881A (pt) | 2002-05-07 |
EP1140028A1 (en) | 2001-10-10 |
MXPA01007018A (es) | 2005-07-01 |
WO2000041678A1 (en) | 2000-07-20 |
DE69928567D1 (de) | 2005-12-29 |
US20010038849A1 (en) | 2001-11-08 |
US6350464B1 (en) | 2002-02-26 |
ZA200106499B (en) | 2002-11-07 |
CN1337878A (zh) | 2002-02-27 |
ATE310506T1 (de) | 2005-12-15 |
CA2359109C (en) | 2011-02-22 |
HUP0202670A2 (hu) | 2002-11-28 |
NO20013402L (no) | 2001-09-11 |
RU2001122708A (ru) | 2004-02-20 |
AU2059100A (en) | 2000-08-01 |
IL145087A0 (en) | 2002-06-30 |
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