ATE216712T1 - Zweistufige lösungspolymerisation von hochmolekularen poly(phosphorestern) - Google Patents
Zweistufige lösungspolymerisation von hochmolekularen poly(phosphorestern)Info
- Publication number
- ATE216712T1 ATE216712T1 AT98930301T AT98930301T ATE216712T1 AT E216712 T1 ATE216712 T1 AT E216712T1 AT 98930301 T AT98930301 T AT 98930301T AT 98930301 T AT98930301 T AT 98930301T AT E216712 T1 ATE216712 T1 AT E216712T1
- Authority
- AT
- Austria
- Prior art keywords
- formula
- polymer
- solvent
- compound
- phosphoresters
- Prior art date
Links
- 238000010528 free radical solution polymerization reaction Methods 0.000 title 1
- 229920000642 polymer Polymers 0.000 abstract 4
- 239000002904 solvent Substances 0.000 abstract 4
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 230000000379 polymerizing effect Effects 0.000 abstract 2
- 239000011541 reaction mixture Substances 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000004104 aryloxy group Chemical group 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G79/00—Macromolecular compounds obtained by reactions forming a linkage containing atoms other than silicon, sulfur, nitrogen, oxygen, and carbon with or without the latter elements in the main chain of the macromolecule
- C08G79/02—Macromolecular compounds obtained by reactions forming a linkage containing atoms other than silicon, sulfur, nitrogen, oxygen, and carbon with or without the latter elements in the main chain of the macromolecule a linkage containing phosphorus
- C08G79/04—Phosphorus linked to oxygen or to oxygen and carbon
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
- Polyesters Or Polycarbonates (AREA)
- Manufacture Of Macromolecular Shaped Articles (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US87762497A | 1997-06-18 | 1997-06-18 | |
| PCT/US1998/012553 WO1998058012A1 (en) | 1997-06-18 | 1998-06-17 | Two-stage solution polymerization of high molecular weight poly(phosphoesters) |
| US09/098,620 US6008318A (en) | 1997-06-18 | 1998-06-17 | Two-stage solution polymerization of high molecular weight poly(phosphoesters) |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE216712T1 true ATE216712T1 (de) | 2002-05-15 |
Family
ID=25370360
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98930301T ATE216712T1 (de) | 1997-06-18 | 1998-06-17 | Zweistufige lösungspolymerisation von hochmolekularen poly(phosphorestern) |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6008318A (de) |
| EP (1) | EP0991699B1 (de) |
| JP (1) | JP2002515939A (de) |
| AT (1) | ATE216712T1 (de) |
| AU (1) | AU746351B2 (de) |
| CA (1) | CA2295209A1 (de) |
| DE (1) | DE69805071T2 (de) |
| WO (1) | WO1998058012A1 (de) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20010006026A (ko) | 1997-04-03 | 2001-01-15 | 존스 홉킨스 유니버시티 스쿨 오브 메디슨 | 생물분해성 테레프탈레이트 폴리에스테르-폴리(포스페이트) 중합체, 조성물, 약품 및 그의 제조방법과 이용방법 |
| UA54505C2 (uk) | 1997-04-03 | 2003-03-17 | Гілфорд Фармасьютікалз Інк. | Полімери, що біологічно розкладаються, зшиті фосфатами, композиції, вироби і способи для їх виготовлення і використання |
| EP1096957A1 (de) | 1998-06-18 | 2001-05-09 | Johns Hopkins University School of Medicine | Verfahren und reagentien zur intramuskulären zufuhr von nukleinsäuren |
| US6153212A (en) | 1998-10-02 | 2000-11-28 | Guilford Pharmaceuticals Inc. | Biodegradable terephthalate polyester-poly (phosphonate) compositions, articles, and methods of using the same |
| US6419709B1 (en) | 1998-10-02 | 2002-07-16 | Guilford Pharmaceuticals, Inc. | Biodegradable terephthalate polyester-poly(Phosphite) compositions, articles, and methods of using the same |
| US6350464B1 (en) | 1999-01-11 | 2002-02-26 | Guilford Pharmaceuticals, Inc. | Methods for treating ovarian cancer, poly (phosphoester) compositions, and biodegradable articles for same |
| US6537585B1 (en) | 1999-03-26 | 2003-03-25 | Guilford Pharmaceuticals, Inc. | Methods and compositions for treating solid tumors |
| WO2002004544A2 (en) | 2000-07-06 | 2002-01-17 | Guilford Pharmaceuticals | Polymers and polymerization processes |
| SG125885A1 (en) * | 2000-12-05 | 2006-10-30 | Univ Singapore | A polymer and nerve guide conduits formed thereof |
| US6555581B1 (en) | 2001-02-15 | 2003-04-29 | Jones Pharma, Inc. | Levothyroxine compositions and methods |
| JP2004525109A (ja) | 2001-02-15 | 2004-08-19 | キング・ファーマシューティカルズ・インコーポレイティッド | 安定化された甲状腺ホルモン医薬組成物、及びその製法 |
| WO2003007915A2 (en) * | 2001-07-19 | 2003-01-30 | Guilford Pharmaceuticals, Inc. | Compositions for treatment of head and neck cancers, and methods of making and using the same |
| WO2003007914A2 (en) * | 2001-07-19 | 2003-01-30 | Guilford Pharmaceuticals, Inc. | Biocompatible polymer containing composition for treatment of prostate cancers |
| US7101569B2 (en) | 2001-08-14 | 2006-09-05 | Franz G Andrew | Methods of administering levothyroxine pharmaceutical compositions |
| US20040043066A1 (en) * | 2001-10-29 | 2004-03-04 | Franz G. Andrew | Levothyroxine compositions having unique triiodothyronine Tmax properties |
| AU2003216424A1 (en) * | 2002-02-25 | 2003-10-08 | Guilford Pharmaceuticals, Inc. | Phosphorus-containing compounds with polymeric chains, and methods of making and using the same |
| US20040197301A1 (en) * | 2003-02-18 | 2004-10-07 | Zhong Zhao | Hybrid polymers and methods of making the same |
| WO2006020616A1 (en) * | 2004-08-13 | 2006-02-23 | Reva Medical, Inc. | Inherently radiopaque bioresorbable polymers for multiple uses |
| CA2669846C (en) * | 2006-11-16 | 2015-02-10 | The University Of Akron | Materials and methods for introducing genetic material into living cells |
| EP2995303A1 (de) | 2009-07-10 | 2016-03-16 | President and Fellows of Harvard College | Permanent geladene natrium- und calciumkanalblocker als entzündungshemmende mittel |
| CN105984147B (zh) | 2015-02-04 | 2018-11-30 | 三纬国际立体列印科技股份有限公司 | 立体打印装置 |
| WO2017024037A1 (en) | 2015-08-03 | 2017-02-09 | President And Fellows Of Harvard College | Charged ion channel blockers and methods for use |
| BR112021017809A2 (pt) | 2019-03-11 | 2021-11-23 | Nocion Therapeutics Inc | Bloqueadores de canais iônicos substituídos por éster e métodos para uso |
| US10780083B1 (en) | 2019-03-11 | 2020-09-22 | Nocion Therapeutics, Inc. | Charged ion channel blockers and methods for use |
| EP3937945A4 (de) | 2019-03-11 | 2023-01-04 | Nocion Therapeutics, Inc. | Geladene ionenkanalblocker und verfahren zur verwendung |
| MA55307A (fr) | 2019-03-11 | 2022-01-19 | Nocion Therapeutics Inc | Bloqueurs de canaux ioniques chargés et procédés d'utilisation |
| US10786485B1 (en) | 2019-03-11 | 2020-09-29 | Nocion Therapeutics, Inc. | Charged ion channel blockers and methods for use |
| WO2021091585A1 (en) | 2019-11-06 | 2021-05-14 | Nocion Therapeutics, Inc. | Charged ion channel blockers and methods for use |
| US10933055B1 (en) | 2019-11-06 | 2021-03-02 | Nocion Therapeutics, Inc. | Charged ion channel blockers and methods for use |
| US12162851B2 (en) | 2020-03-11 | 2024-12-10 | Nocion Therapeutics, Inc. | Charged ion channel blockers and methods for use |
| JP7708777B2 (ja) | 2020-03-11 | 2025-07-15 | ノシオン セラピューティクス，インコーポレイテッド | 荷電したイオンチャンネル遮断薬および使用方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5750812B2 (de) * | 1973-06-25 | 1982-10-29 | ||
| US5265265A (en) * | 1990-02-09 | 1993-11-23 | Seiko Epson Corporation | Wristwatch radio communication device having an improved noise shielding structure |
| US5194581A (en) * | 1989-03-09 | 1993-03-16 | Leong Kam W | Biodegradable poly(phosphoesters) |
| US5256265A (en) * | 1991-03-18 | 1993-10-26 | Cha Chang Y | Process for oxide reactions by radiofrequency-char catalysis |
-
1998
- 1998-06-17 WO PCT/US1998/012553 patent/WO1998058012A1/en not_active Ceased
- 1998-06-17 AU AU79721/98A patent/AU746351B2/en not_active Ceased
- 1998-06-17 DE DE69805071T patent/DE69805071T2/de not_active Expired - Fee Related
- 1998-06-17 AT AT98930301T patent/ATE216712T1/de not_active IP Right Cessation
- 1998-06-17 US US09/098,620 patent/US6008318A/en not_active Expired - Lifetime
- 1998-06-17 EP EP98930301A patent/EP0991699B1/de not_active Expired - Lifetime
- 1998-06-17 CA CA002295209A patent/CA2295209A1/en not_active Withdrawn
- 1998-06-17 JP JP50470699A patent/JP2002515939A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| DE69805071T2 (de) | 2002-11-14 |
| EP0991699A1 (de) | 2000-04-12 |
| WO1998058012A1 (en) | 1998-12-23 |
| AU746351B2 (en) | 2002-04-18 |
| DE69805071D1 (de) | 2002-05-29 |
| CA2295209A1 (en) | 1998-12-23 |
| JP2002515939A (ja) | 2002-05-28 |
| US6008318A (en) | 1999-12-28 |
| EP0991699B1 (de) | 2002-04-24 |
| AU7972198A (en) | 1999-01-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |