CN1367684A - 治疗实体瘤的方法和组合物 - Google Patents

治疗实体瘤的方法和组合物 Download PDF

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Publication number
CN1367684A
CN1367684A CN00806972A CN00806972A CN1367684A CN 1367684 A CN1367684 A CN 1367684A CN 00806972 A CN00806972 A CN 00806972A CN 00806972 A CN00806972 A CN 00806972A CN 1367684 A CN1367684 A CN 1367684A
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CN
China
Prior art keywords
tumor
compositions
poly
antitumor agent
paclitaxel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN00806972A
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English (en)
Chinese (zh)
Inventor
党文兵
R·I·小加弗
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eisai Corp of North America
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Guilford Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Guilford Pharmaceuticals Inc filed Critical Guilford Pharmaceuticals Inc
Publication of CN1367684A publication Critical patent/CN1367684A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Dermatology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Materials For Medical Uses (AREA)
CN00806972A 1999-03-26 2000-03-20 治疗实体瘤的方法和组合物 Pending CN1367684A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/276,866 1999-03-26
US09/276,866 US6537585B1 (en) 1999-03-26 1999-03-26 Methods and compositions for treating solid tumors

Publications (1)

Publication Number Publication Date
CN1367684A true CN1367684A (zh) 2002-09-04

Family

ID=23058398

Family Applications (1)

Application Number Title Priority Date Filing Date
CN00806972A Pending CN1367684A (zh) 1999-03-26 2000-03-20 治疗实体瘤的方法和组合物

Country Status (17)

Country Link
US (2) US6537585B1 (https=)
EP (1) EP1185249B1 (https=)
JP (2) JP2002540137A (https=)
KR (1) KR20010111578A (https=)
CN (1) CN1367684A (https=)
AT (1) ATE306251T1 (https=)
AU (1) AU778279B2 (https=)
BR (1) BR0009213A (https=)
CA (1) CA2368621C (https=)
CZ (1) CZ20013260A3 (https=)
DE (1) DE60023138T2 (https=)
HU (1) HUP0201436A3 (https=)
IL (1) IL145492A0 (https=)
NO (1) NO20014662L (https=)
PL (1) PL351280A1 (https=)
TR (1) TR200102801T2 (https=)
WO (1) WO2000057852A2 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101390828B (zh) * 2007-02-12 2010-06-09 济南康泉医药科技有限公司 同载抗代谢类药物和增效剂的抗癌组合物

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101390828B (zh) * 2007-02-12 2010-06-09 济南康泉医药科技有限公司 同载抗代谢类药物和增效剂的抗癌组合物

Also Published As

Publication number Publication date
CZ20013260A3 (cs) 2002-01-16
BR0009213A (pt) 2002-04-16
CA2368621A1 (en) 2000-10-05
DE60023138T2 (de) 2006-08-17
US20030203033A1 (en) 2003-10-30
AU3762500A (en) 2000-10-16
CA2368621C (en) 2010-05-25
NO20014662L (no) 2001-11-20
NO20014662D0 (no) 2001-09-25
EP1185249B1 (en) 2005-10-12
US6537585B1 (en) 2003-03-25
EP1185249A2 (en) 2002-03-13
DE60023138D1 (de) 2006-02-23
US7101568B2 (en) 2006-09-05
AU778279B2 (en) 2004-11-25
IL145492A0 (en) 2002-06-30
WO2000057852A3 (en) 2001-02-15
PL351280A1 (en) 2003-04-07
ATE306251T1 (de) 2005-10-15
JP2002540137A (ja) 2002-11-26
TR200102801T2 (tr) 2002-04-22
WO2000057852A2 (en) 2000-10-05
HUP0201436A3 (en) 2003-04-28
HUP0201436A2 (en) 2002-09-28
JP2011219483A (ja) 2011-11-04
KR20010111578A (ko) 2001-12-19

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