TR200000928T2 - Yeni kombinasyon. - Google Patents
Yeni kombinasyon.Info
- Publication number
- TR200000928T2 TR200000928T2 TR2000/00928T TR200000928T TR200000928T2 TR 200000928 T2 TR200000928 T2 TR 200000928T2 TR 2000/00928 T TR2000/00928 T TR 2000/00928T TR 200000928 T TR200000928 T TR 200000928T TR 200000928 T2 TR200000928 T2 TR 200000928T2
- Authority
- TR
- Turkey
- Prior art keywords
- new combination
- inhibitor
- inflammatory
- cyclooxygenase
- administration
- Prior art date
Links
- 239000003112 inhibitor Substances 0.000 abstract 2
- 102000010907 Cyclooxygenase 2 Human genes 0.000 abstract 1
- 108010037462 Cyclooxygenase 2 Proteins 0.000 abstract 1
- 102000008299 Nitric Oxide Synthase Human genes 0.000 abstract 1
- 108010021487 Nitric Oxide Synthase Proteins 0.000 abstract 1
- 238000011260 co-administration Methods 0.000 abstract 1
- 208000027866 inflammatory disease Diseases 0.000 abstract 1
- 230000002757 inflammatory effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Abstract
Bulus, uyarilmis nitrik oksit sintazinin bir önleyicisi ile siklooksigenaz-2'nin bir önleyicisinin iltihap ve iltihabik bozukluklarin tedavisi için birlikte uygulanmasiyla ilgilidir.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9703693A SE9703693D0 (sv) | 1997-10-10 | 1997-10-10 | Novel combination |
Publications (1)
Publication Number | Publication Date |
---|---|
TR200000928T2 true TR200000928T2 (tr) | 2000-11-21 |
Family
ID=20408563
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR2000/00928T TR200000928T2 (tr) | 1997-10-10 | 1998-10-05 | Yeni kombinasyon. |
Country Status (20)
Country | Link |
---|---|
US (1) | US6046191A (tr) |
EP (1) | EP1027052A1 (tr) |
JP (1) | JP2001519391A (tr) |
KR (1) | KR20010031017A (tr) |
CN (1) | CN1281362A (tr) |
AU (1) | AU9469398A (tr) |
BR (1) | BR9812753A (tr) |
CA (1) | CA2305141A1 (tr) |
CZ (1) | CZ20001272A3 (tr) |
EE (1) | EE200000192A (tr) |
HU (1) | HUP0003874A2 (tr) |
IL (1) | IL135248A0 (tr) |
IS (1) | IS5430A (tr) |
MX (1) | MXPA00003445A (tr) |
NO (1) | NO20001830L (tr) |
PL (1) | PL339769A1 (tr) |
SE (1) | SE9703693D0 (tr) |
SK (1) | SK4282000A3 (tr) |
TR (1) | TR200000928T2 (tr) |
WO (1) | WO1999018960A1 (tr) |
Families Citing this family (46)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE9701304D0 (sv) * | 1997-04-09 | 1997-04-09 | Astra Pharma Prod | Compounds |
EE200100084A (xx) * | 1998-08-11 | 2002-08-15 | Pfizer Products Inc. | NOS inhibiitorite uued farmatseutilised kasutusv�imalused |
MXPA02006312A (es) | 1999-12-23 | 2004-06-21 | Nitromed Inc | Inhibidores de ciclooxigenasa-2 nitrosilatados y nitrosados, composiciones y metodos para utilizarse. |
GB0004153D0 (en) * | 2000-02-23 | 2000-04-12 | Astrazeneca Uk Ltd | Novel use |
US6800297B2 (en) * | 2000-06-15 | 2004-10-05 | Acusphere, Inc. | Porous COX-2 inhibitor matrices and methods of manufacture thereof |
US6589557B2 (en) * | 2000-06-15 | 2003-07-08 | Acusphere, Inc. | Porous celecoxib matrices and methods of manufacture thereof |
US20020035107A1 (en) | 2000-06-20 | 2002-03-21 | Stefan Henke | Highly concentrated stable meloxicam solutions |
IN191090B (tr) * | 2000-08-29 | 2003-09-20 | Ranbanx Lab Ltd | |
WO2002017896A2 (en) * | 2000-08-29 | 2002-03-07 | Peter Van Patten | Combination for the treatment of migraine comprising a cyclooxygenase-2 inhibitor and acetylsalicylic acid |
US7012098B2 (en) * | 2001-03-23 | 2006-03-14 | Pharmacia Corporation | Inhibitors of inducible nitric oxide synthase for chemoprevention and treatment of cancers |
US20030035795A1 (en) * | 2001-04-13 | 2003-02-20 | Gardell Stephen J. | Methods for treating or reducing the risk of pain and inflammatory disorders by administering inhibitors of activated thrombin activatable fibrinolysis inhibitor |
US20020187187A1 (en) * | 2001-04-21 | 2002-12-12 | Toshimitsu Ohki | Fast disintegrating meloxicam tablet |
AR035700A1 (es) * | 2001-05-08 | 2004-06-23 | Astrazeneca Ab | Derivados de arilheteroalquilamina, composicion farmaceutica, usos de estos derivados para la fabricacion de medicamentos, metodos de tratamiento, y proceso para la preparacion de estos derivados |
US20030114418A1 (en) * | 2001-08-14 | 2003-06-19 | Pharmacia Corporation | Method for the treatment and prevention of pain and inflammation with glucosamine and a cyclooxygenase-2 selective inhibitor and compositions therefor |
WO2003035080A2 (en) * | 2001-08-28 | 2003-05-01 | Ranbaxy Laboratories Limited | A process for the preparation of pharmaceutical compositions for topical delivery of cyclooxygenase-2 enzyme inhibitors |
KR20050044459A (ko) * | 2001-11-13 | 2005-05-12 | 파마시아 코포레이션 | 파레콕시브 등의 설폰아미드 선구약물의 경구 투여 형태 |
DE10161077A1 (de) | 2001-12-12 | 2003-06-18 | Boehringer Ingelheim Vetmed | Hochkonzentrierte stabile Meloxicamlösungen zur nadellosen Injektion |
KR20050005410A (ko) * | 2002-02-19 | 2005-01-13 | 파마시아 코포레이션 | 요실금 치료용으로서의 시클로옥시게나제 저해제 및항무스카린제의 용도 |
US7220749B2 (en) | 2002-06-11 | 2007-05-22 | Nitromed, Inc. | Nitrosated and/or nitrosylated cyclooxygenase-2 selective inhibitors, compositions and methods of use |
CA2493156A1 (en) * | 2002-07-29 | 2004-02-05 | Nitromed, Inc. | Cyclooxygenase-2 selective inhibitors, compositions and methods of use |
US8992980B2 (en) | 2002-10-25 | 2015-03-31 | Boehringer Ingelheim Vetmedica Gmbh | Water-soluble meloxicam granules |
SI1622630T1 (sl) * | 2003-05-07 | 2012-12-31 | Osteologix A/S | Stroncijeva kombinacije za profilakso/zdravljenje patologij hrustanca in/ali kosti |
JP4354984B2 (ja) * | 2003-05-07 | 2009-10-28 | オステオロジックス エイ/エス | 水溶性ストロンチウム塩を用いる軟骨/骨症状の治療 |
EP1568369A1 (en) | 2004-02-23 | 2005-08-31 | Boehringer Ingelheim Vetmedica Gmbh | Use of meloxicam for the treatment of respiratory diseases in pigs |
DE102004021281A1 (de) * | 2004-04-29 | 2005-11-24 | Boehringer Ingelheim Vetmedica Gmbh | Verwendung von Meloxicam-Formulierungen in der Veterinärmedizin |
CA2570503A1 (en) * | 2004-06-17 | 2005-12-29 | Osteologix A/S | A method of improving the medical treatment of pain |
DE102004030409A1 (de) * | 2004-06-23 | 2006-01-26 | Boehringer Ingelheim Vetmedica Gmbh | Neue Verwendung von Meloxicam in der Veterinärmedizin |
JP2009510007A (ja) * | 2005-09-30 | 2009-03-12 | ベーリンガー インゲルハイム フェトメディカ ゲゼルシャフト ミット ベシュレンクテル ハフツング | メロキシカムを含む医薬調製 |
ES2537898T3 (es) | 2005-10-25 | 2015-06-15 | Shionogi & Co., Ltd. | Derivados de aminotiazolidina y aminotetrahidrotiazepina como inhibidores de BACE 1 |
JP2007275193A (ja) * | 2006-04-04 | 2007-10-25 | Fujifilm Corp | 光プローブおよび光断層画像化装置 |
GB0712287D0 (en) * | 2007-06-22 | 2007-08-01 | Ucl Business Plc | Antimicrobial Conjugates |
US20090317436A1 (en) * | 2006-08-04 | 2009-12-24 | Mike Wilson | Computer devices and accessories |
JP2010516679A (ja) * | 2007-01-19 | 2010-05-20 | マリンクロット インコーポレイテッド | 診断用および治療用シクロオキシゲナーゼ−2結合リガンド |
JP5383484B2 (ja) | 2007-04-24 | 2014-01-08 | 塩野義製薬株式会社 | 環式基で置換されたアミノジヒドロチアジン誘導体 |
JP5383483B2 (ja) | 2007-04-24 | 2014-01-08 | 塩野義製薬株式会社 | アルツハイマー症治療用医薬組成物 |
DE102007049612A1 (de) * | 2007-10-17 | 2009-06-10 | Evonik Goldschmidt Gmbh | Bioaktive Zusammensetzung für kosmetische Anwendungen |
US8637504B2 (en) | 2008-06-13 | 2014-01-28 | Shionogi & Co., Ltd. | Sulfur-containing heterocyclic derivative having beta secretase inhibitory activity |
JPWO2010047372A1 (ja) | 2008-10-22 | 2012-03-22 | 塩野義製薬株式会社 | Bace1阻害活性を有する2−アミノピリミジン−4−オンおよび2−アミノピリジン誘導体 |
CN102647971B (zh) | 2009-10-12 | 2016-03-16 | 贝林格尔.英格海姆维特梅迪卡有限公司 | 用于包含美洛昔康的组合物的容器 |
BR112012013854A2 (pt) | 2009-12-11 | 2019-09-24 | Shionogi & Co | derivados de oxazina. |
AU2010347598B2 (en) | 2010-03-03 | 2014-11-27 | Boehringer Ingelheim Vetmedica Gmbh | Use of meloxicam for the long-term treatment of musculoskeletal disorders in cats |
US9795568B2 (en) | 2010-05-05 | 2017-10-24 | Boehringer Ingelheim Vetmedica Gmbh | Low concentration meloxicam tablets |
JP5816630B2 (ja) | 2010-10-29 | 2015-11-18 | 塩野義製薬株式会社 | ナフチリジン誘導体 |
WO2012057247A1 (ja) | 2010-10-29 | 2012-05-03 | 塩野義製薬株式会社 | 縮合アミノジヒドロピリミジン誘導体 |
WO2012147763A1 (ja) | 2011-04-26 | 2012-11-01 | 塩野義製薬株式会社 | オキサジン誘導体およびそれを含有するbace1阻害剤 |
WO2014065434A1 (en) | 2012-10-24 | 2014-05-01 | Shionogi & Co., Ltd. | Dihydrooxazine or oxazepine derivatives having bace1 inhibitory activity |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2224563A1 (en) * | 1995-06-12 | 1996-12-27 | G.D. Searle & Co. | Combination of a cyclooxygenase-2 inhibitor and a leukotriene b4 receptor antagonist for the treatment of inflammations |
DE69635048T2 (de) * | 1995-06-12 | 2006-02-16 | G.D. Searle & Co. | Mittel, enthaltend einen cyclooxygenase-2 inhibitor und einen 5-lipoxygenase inhibitor |
ES2183140T3 (es) * | 1996-02-13 | 2003-03-16 | Searle & Co | Combinaciones, que tienen efectos inmunosupresores, que contienen un inhibidor de ciclooxigenasa-2 y un inhibidor de leucotrieno a4 hidrolasa. |
-
1997
- 1997-10-10 SE SE9703693A patent/SE9703693D0/xx unknown
-
1998
- 1998-10-05 MX MXPA00003445 patent/MXPA00003445A/es unknown
- 1998-10-05 EP EP98948031A patent/EP1027052A1/en not_active Withdrawn
- 1998-10-05 HU HU0003874A patent/HUP0003874A2/hu unknown
- 1998-10-05 TR TR2000/00928T patent/TR200000928T2/tr unknown
- 1998-10-05 CN CN98812081A patent/CN1281362A/zh active Pending
- 1998-10-05 KR KR1020007003824A patent/KR20010031017A/ko not_active Application Discontinuation
- 1998-10-05 EE EEP200000192A patent/EE200000192A/xx unknown
- 1998-10-05 CA CA002305141A patent/CA2305141A1/en not_active Abandoned
- 1998-10-05 JP JP2000515595A patent/JP2001519391A/ja active Pending
- 1998-10-05 SK SK428-2000A patent/SK4282000A3/sk unknown
- 1998-10-05 PL PL98339769A patent/PL339769A1/xx unknown
- 1998-10-05 BR BR9812753-5A patent/BR9812753A/pt not_active IP Right Cessation
- 1998-10-05 WO PCT/SE1998/001792 patent/WO1999018960A1/en not_active Application Discontinuation
- 1998-10-05 CZ CZ20001272A patent/CZ20001272A3/cs unknown
- 1998-10-05 US US09/171,801 patent/US6046191A/en not_active Expired - Fee Related
- 1998-10-05 IL IL13524898A patent/IL135248A0/xx unknown
- 1998-10-05 AU AU94693/98A patent/AU9469398A/en not_active Abandoned
-
2000
- 2000-04-06 IS IS5430A patent/IS5430A/is unknown
- 2000-04-07 NO NO20001830A patent/NO20001830L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
IS5430A (is) | 2000-04-06 |
NO20001830D0 (no) | 2000-04-07 |
PL339769A1 (en) | 2001-01-02 |
SE9703693D0 (sv) | 1997-10-10 |
CZ20001272A3 (cs) | 2000-09-13 |
NO20001830L (no) | 2000-05-10 |
WO1999018960A1 (en) | 1999-04-22 |
CA2305141A1 (en) | 1999-04-22 |
JP2001519391A (ja) | 2001-10-23 |
AU9469398A (en) | 1999-05-03 |
IL135248A0 (en) | 2001-05-20 |
SK4282000A3 (en) | 2001-01-18 |
EE200000192A (et) | 2001-04-16 |
BR9812753A (pt) | 2000-08-29 |
US6046191A (en) | 2000-04-04 |
MXPA00003445A (es) | 2001-06-01 |
CN1281362A (zh) | 2001-01-24 |
EP1027052A1 (en) | 2000-08-16 |
HUP0003874A2 (hu) | 2001-05-28 |
KR20010031017A (ko) | 2001-04-16 |
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