BR9812753A - Combinação farmacêutica, uso da mesma, processo para tratamento de uma doença inflamatória, e, composição farmacêutica - Google Patents
Combinação farmacêutica, uso da mesma, processo para tratamento de uma doença inflamatória, e, composição farmacêuticaInfo
- Publication number
- BR9812753A BR9812753A BR9812753-5A BR9812753A BR9812753A BR 9812753 A BR9812753 A BR 9812753A BR 9812753 A BR9812753 A BR 9812753A BR 9812753 A BR9812753 A BR 9812753A
- Authority
- BR
- Brazil
- Prior art keywords
- treating
- inflammatory disease
- pharmaceutical composition
- pharmaceutical
- pharmaceutical combination
- Prior art date
Links
- 208000027866 inflammatory disease Diseases 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- MWUXSHHQAYIFBG-UHFFFAOYSA-N Nitric oxide Chemical compound O=[N] MWUXSHHQAYIFBG-UHFFFAOYSA-N 0.000 abstract 2
- 229940093444 Cyclooxygenase 2 inhibitor Drugs 0.000 abstract 1
- 206010061218 Inflammation Diseases 0.000 abstract 1
- 238000011260 co-administration Methods 0.000 abstract 1
- 239000003255 cyclooxygenase 2 inhibitor Substances 0.000 abstract 1
- 230000004054 inflammatory process Effects 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Rheumatology (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Engineering & Computer Science (AREA)
- Physical Education & Sports Medicine (AREA)
- Pain & Pain Management (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Abstract
''COMBINAçãO FARMACêUTICA, USO DA MESMA, PROCESSO PARA TRATAMENTO DE UMA DOENçA INFLAMATóRIA, E, COMPOSIçãO FARMACêUTICA'' A invenção se relaciona com a co-administração de um inibidor de sintase induzida de óxido nítrico e um inibidor de ciclooxigenase-2 para o tratamento de inflamação e distúrbios inflamatórios.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9703693A SE9703693D0 (sv) | 1997-10-10 | 1997-10-10 | Novel combination |
PCT/SE1998/001792 WO1999018960A1 (en) | 1997-10-10 | 1998-10-05 | Novel combination |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9812753A true BR9812753A (pt) | 2000-08-29 |
Family
ID=20408563
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9812753-5A BR9812753A (pt) | 1997-10-10 | 1998-10-05 | Combinação farmacêutica, uso da mesma, processo para tratamento de uma doença inflamatória, e, composição farmacêutica |
Country Status (20)
Country | Link |
---|---|
US (1) | US6046191A (pt) |
EP (1) | EP1027052A1 (pt) |
JP (1) | JP2001519391A (pt) |
KR (1) | KR20010031017A (pt) |
CN (1) | CN1281362A (pt) |
AU (1) | AU9469398A (pt) |
BR (1) | BR9812753A (pt) |
CA (1) | CA2305141A1 (pt) |
CZ (1) | CZ20001272A3 (pt) |
EE (1) | EE200000192A (pt) |
HU (1) | HUP0003874A2 (pt) |
IL (1) | IL135248A0 (pt) |
IS (1) | IS5430A (pt) |
MX (1) | MXPA00003445A (pt) |
NO (1) | NO20001830L (pt) |
PL (1) | PL339769A1 (pt) |
SE (1) | SE9703693D0 (pt) |
SK (1) | SK4282000A3 (pt) |
TR (1) | TR200000928T2 (pt) |
WO (1) | WO1999018960A1 (pt) |
Families Citing this family (46)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE9701304D0 (sv) * | 1997-04-09 | 1997-04-09 | Astra Pharma Prod | Compounds |
CN1323211A (zh) * | 1998-08-11 | 2001-11-21 | 辉瑞产品公司 | Nos抑制剂的新药学用途 |
NZ519781A (en) * | 1999-12-23 | 2004-04-30 | Nitromed Inc | Nitrosated and nitrosylated cyclooxygenase-2 inhibitors, compositions and methods of use |
GB0004153D0 (en) * | 2000-02-23 | 2000-04-12 | Astrazeneca Uk Ltd | Novel use |
US6800297B2 (en) * | 2000-06-15 | 2004-10-05 | Acusphere, Inc. | Porous COX-2 inhibitor matrices and methods of manufacture thereof |
US6589557B2 (en) * | 2000-06-15 | 2003-07-08 | Acusphere, Inc. | Porous celecoxib matrices and methods of manufacture thereof |
US20020035107A1 (en) * | 2000-06-20 | 2002-03-21 | Stefan Henke | Highly concentrated stable meloxicam solutions |
WO2002017896A2 (en) * | 2000-08-29 | 2002-03-07 | Peter Van Patten | Combination for the treatment of migraine comprising a cyclooxygenase-2 inhibitor and acetylsalicylic acid |
IN191090B (pt) * | 2000-08-29 | 2003-09-20 | Ranbanx Lab Ltd | |
US7012098B2 (en) * | 2001-03-23 | 2006-03-14 | Pharmacia Corporation | Inhibitors of inducible nitric oxide synthase for chemoprevention and treatment of cancers |
US20030035795A1 (en) * | 2001-04-13 | 2003-02-20 | Gardell Stephen J. | Methods for treating or reducing the risk of pain and inflammatory disorders by administering inhibitors of activated thrombin activatable fibrinolysis inhibitor |
US20020187187A1 (en) * | 2001-04-21 | 2002-12-12 | Toshimitsu Ohki | Fast disintegrating meloxicam tablet |
AR035700A1 (es) * | 2001-05-08 | 2004-06-23 | Astrazeneca Ab | Derivados de arilheteroalquilamina, composicion farmaceutica, usos de estos derivados para la fabricacion de medicamentos, metodos de tratamiento, y proceso para la preparacion de estos derivados |
US20030114418A1 (en) * | 2001-08-14 | 2003-06-19 | Pharmacia Corporation | Method for the treatment and prevention of pain and inflammation with glucosamine and a cyclooxygenase-2 selective inhibitor and compositions therefor |
US20050049291A1 (en) * | 2001-10-23 | 2005-03-03 | Mukesh Kumar | Process for the preparation of pharmaceutical compositions for topical delivery of cyclooxygenase-2-enzyme inhibitors |
AR037356A1 (es) * | 2001-11-13 | 2004-11-03 | Pharmacia Corp | Forma de dosificacion oral de una prodroga de sulfonamida |
DE10161077A1 (de) * | 2001-12-12 | 2003-06-18 | Boehringer Ingelheim Vetmed | Hochkonzentrierte stabile Meloxicamlösungen zur nadellosen Injektion |
PL372395A1 (en) * | 2002-02-19 | 2005-07-25 | Pharmacia Corporation | Use of cyclooxygenase inhibitors and antimuscarinic agents for the treatment of incontinence |
AU2003248642A1 (en) | 2002-06-11 | 2003-12-22 | Nitromed, Inc. | Nitrosated and/or nitrosylated cyclooxygenase-2 selective inhibitors, compositions and methods of use |
AU2003261281A1 (en) * | 2002-07-29 | 2004-02-16 | Nicox S.A. | Cyclooxygenase- 2 selective inhibitors, compositions and methods of use |
US8992980B2 (en) * | 2002-10-25 | 2015-03-31 | Boehringer Ingelheim Vetmedica Gmbh | Water-soluble meloxicam granules |
AU2004237438B2 (en) * | 2003-05-07 | 2011-01-20 | Osteologix A/S | Strontium combinations for prophylaxis/treatment of cartilage and/or bone conditions |
CA2519189C (en) | 2003-05-07 | 2012-07-17 | Osteologix A/S | Water-soluble strontium salts for use in treatment of cartilage and/or bone conditions |
EP1568369A1 (en) * | 2004-02-23 | 2005-08-31 | Boehringer Ingelheim Vetmedica Gmbh | Use of meloxicam for the treatment of respiratory diseases in pigs |
DE102004021281A1 (de) * | 2004-04-29 | 2005-11-24 | Boehringer Ingelheim Vetmedica Gmbh | Verwendung von Meloxicam-Formulierungen in der Veterinärmedizin |
AU2005254154A1 (en) * | 2004-06-17 | 2005-12-29 | Osteologix A/S | Improving pain treatment with strontium combinations |
DE102004030409A1 (de) * | 2004-06-23 | 2006-01-26 | Boehringer Ingelheim Vetmedica Gmbh | Neue Verwendung von Meloxicam in der Veterinärmedizin |
WO2007039417A1 (en) * | 2005-09-30 | 2007-04-12 | Boehringer Ingelheim Vetmedica Gmbh | Pharmaceutical preparation containing meloxicam |
ES2572263T3 (es) | 2005-10-25 | 2016-05-31 | Shionogi & Co | Derivados de dihidrooxazina y tetrahidropirimidina como inhibidores de BACE 1 |
JP2007275193A (ja) * | 2006-04-04 | 2007-10-25 | Fujifilm Corp | 光プローブおよび光断層画像化装置 |
GB0712287D0 (en) * | 2007-06-22 | 2007-08-01 | Ucl Business Plc | Antimicrobial Conjugates |
WO2008015445A2 (en) * | 2006-08-04 | 2008-02-07 | Ucl Business Plc | Computer devices and accessories |
US20100111858A1 (en) * | 2007-01-19 | 2010-05-06 | Howard Carol P | Diangostic and Therapeutic Cyclooxygenase-2 Binding Ligands |
EP2151435A4 (en) | 2007-04-24 | 2011-09-14 | Shionogi & Co | PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF ALZHEIMER'S DISEASE |
EP2147914B1 (en) | 2007-04-24 | 2014-06-04 | Shionogi&Co., Ltd. | Aminodihydrothiazine derivatives substituted with cyclic groups |
DE102007049612A1 (de) * | 2007-10-17 | 2009-06-10 | Evonik Goldschmidt Gmbh | Bioaktive Zusammensetzung für kosmetische Anwendungen |
KR101324426B1 (ko) | 2008-06-13 | 2013-10-31 | 시오노기세야쿠 가부시키가이샤 | β 세크레타제 저해 작용을 갖는 황 함유 복소환 유도체 |
EP2360155A4 (en) | 2008-10-22 | 2012-06-20 | Shionogi & Co | 2-AMINOPYRIDIN-4-ON AND 2-AMINOPYRIDINE DERIVATIVE WITH BACE1-HEMDERING EFFECT |
CN102647971B (zh) | 2009-10-12 | 2016-03-16 | 贝林格尔.英格海姆维特梅迪卡有限公司 | 用于包含美洛昔康的组合物的容器 |
CN102834384A (zh) | 2009-12-11 | 2012-12-19 | 盐野义制药株式会社 | *嗪衍生物 |
WO2011107150A1 (en) | 2010-03-03 | 2011-09-09 | Boehringer Ingelheim Vetmedica Gmbh | Use of meloxicam for the long-term treatment of musculoskeletal disorders in cats |
US9795568B2 (en) | 2010-05-05 | 2017-10-24 | Boehringer Ingelheim Vetmedica Gmbh | Low concentration meloxicam tablets |
US9018219B2 (en) | 2010-10-29 | 2015-04-28 | Shionogi & Co., Ltd. | Fused aminodihydropyrimidine derivative |
WO2012057248A1 (ja) | 2010-10-29 | 2012-05-03 | 塩野義製薬株式会社 | ナフチリジン誘導体 |
EP2703399A4 (en) | 2011-04-26 | 2014-10-15 | Shionogi & Co | OXAZINE DERIVATIVE AND BACE-1 HEMMER THEREOF |
WO2014065434A1 (en) | 2012-10-24 | 2014-05-01 | Shionogi & Co., Ltd. | Dihydrooxazine or oxazepine derivatives having bace1 inhibitory activity |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0833622B8 (en) * | 1995-06-12 | 2005-10-12 | G.D. Searle & Co. | Compositions comprising a cyclooxygenase-2 inhibitor and a 5-lipoxygenase inhibitor |
CA2224563A1 (en) * | 1995-06-12 | 1996-12-27 | G.D. Searle & Co. | Combination of a cyclooxygenase-2 inhibitor and a leukotriene b4 receptor antagonist for the treatment of inflammations |
WO1997029774A1 (en) * | 1996-02-13 | 1997-08-21 | G.D. Searle & Co. | Combinations, having immunosuppressive effects, containing a cyclooxygenase-2 inhibitor and a leukotriene a4 hydrolase inhibitor |
-
1997
- 1997-10-10 SE SE9703693A patent/SE9703693D0/xx unknown
-
1998
- 1998-10-05 PL PL98339769A patent/PL339769A1/xx unknown
- 1998-10-05 EE EEP200000192A patent/EE200000192A/xx unknown
- 1998-10-05 MX MXPA00003445 patent/MXPA00003445A/es unknown
- 1998-10-05 CN CN98812081A patent/CN1281362A/zh active Pending
- 1998-10-05 IL IL13524898A patent/IL135248A0/xx unknown
- 1998-10-05 BR BR9812753-5A patent/BR9812753A/pt not_active IP Right Cessation
- 1998-10-05 TR TR2000/00928T patent/TR200000928T2/xx unknown
- 1998-10-05 JP JP2000515595A patent/JP2001519391A/ja active Pending
- 1998-10-05 SK SK428-2000A patent/SK4282000A3/sk unknown
- 1998-10-05 EP EP98948031A patent/EP1027052A1/en not_active Withdrawn
- 1998-10-05 KR KR1020007003824A patent/KR20010031017A/ko not_active Application Discontinuation
- 1998-10-05 WO PCT/SE1998/001792 patent/WO1999018960A1/en not_active Application Discontinuation
- 1998-10-05 US US09/171,801 patent/US6046191A/en not_active Expired - Fee Related
- 1998-10-05 CZ CZ20001272A patent/CZ20001272A3/cs unknown
- 1998-10-05 CA CA002305141A patent/CA2305141A1/en not_active Abandoned
- 1998-10-05 AU AU94693/98A patent/AU9469398A/en not_active Abandoned
- 1998-10-05 HU HU0003874A patent/HUP0003874A2/hu unknown
-
2000
- 2000-04-06 IS IS5430A patent/IS5430A/is unknown
- 2000-04-07 NO NO20001830A patent/NO20001830L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
IL135248A0 (en) | 2001-05-20 |
NO20001830L (no) | 2000-05-10 |
MXPA00003445A (es) | 2001-06-01 |
HUP0003874A2 (hu) | 2001-05-28 |
EP1027052A1 (en) | 2000-08-16 |
NO20001830D0 (no) | 2000-04-07 |
JP2001519391A (ja) | 2001-10-23 |
KR20010031017A (ko) | 2001-04-16 |
CZ20001272A3 (cs) | 2000-09-13 |
IS5430A (is) | 2000-04-06 |
TR200000928T2 (tr) | 2000-11-21 |
SE9703693D0 (sv) | 1997-10-10 |
PL339769A1 (en) | 2001-01-02 |
CN1281362A (zh) | 2001-01-24 |
CA2305141A1 (en) | 1999-04-22 |
US6046191A (en) | 2000-04-04 |
EE200000192A (et) | 2001-04-16 |
WO1999018960A1 (en) | 1999-04-22 |
AU9469398A (en) | 1999-05-03 |
SK4282000A3 (en) | 2001-01-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 5O,6O,7O,8O E 9O ANUIDADES |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1909 DE 07/08/2007. |