TR199802163T2 - 4'-Triflorometilbifenil-2-karboksilik asit - Google Patents

4'-Triflorometilbifenil-2-karboksilik asit

Info

Publication number
TR199802163T2
TR199802163T2 TR1998/02163T TR9802163T TR199802163T2 TR 199802163 T2 TR199802163 T2 TR 199802163T2 TR 1998/02163 T TR1998/02163 T TR 1998/02163T TR 9802163 T TR9802163 T TR 9802163T TR 199802163 T2 TR199802163 T2 TR 199802163T2
Authority
TR
Turkey
Prior art keywords
trifluoromethylbiphenyl
carboxylic acid
compound
formula
aryl groups
Prior art date
Application number
TR1998/02163T
Other languages
English (en)
Inventor
John Urban Frank
Original Assignee
Pfizer Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc. filed Critical Pfizer Inc.
Publication of TR199802163T2 publication Critical patent/TR199802163T2/tr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)

Abstract

Isbu bulus(I) formülüne sahip bir bilesim hazirlamak için bir yöntem ile ilgilidir.Bahsedilen yöntemde içinde R, H ya da R olan ve R , içinde ikameler bir ila üç (C6-C10) aril gruplari ihtiva eden aril ya da bir ikame edilmis metil grubundan seçilen bir formül (III) bilesimi -ki aril gruplari nitro ve (C1-C6) alkoksiden seçilen bir ya da daha fazla ikame ile ek olarak ikame edilebilir-takip edenlerden biri ile tepkimeye sokulur.
TR1998/02163T 1996-04-30 1997-03-13 4'-Triflorometilbifenil-2-karboksilik asit TR199802163T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US1649596P 1996-04-30 1996-04-30

Publications (1)

Publication Number Publication Date
TR199802163T2 true TR199802163T2 (tr) 1999-02-22

Family

ID=21777423

Family Applications (1)

Application Number Title Priority Date Filing Date
TR1998/02163T TR199802163T2 (tr) 1996-04-30 1997-03-13 4'-Triflorometilbifenil-2-karboksilik asit

Country Status (23)

Country Link
US (1) US5998623A (tr)
EP (1) EP0902785B1 (tr)
JP (1) JPH11507959A (tr)
KR (1) KR20000065152A (tr)
CN (1) CN1216988A (tr)
AR (1) AR006876A1 (tr)
AT (1) ATE223400T1 (tr)
AU (1) AU711279B2 (tr)
BR (1) BR9709137A (tr)
CA (1) CA2252621C (tr)
CZ (1) CZ346498A3 (tr)
DE (1) DE69715188T2 (tr)
DK (1) DK0902785T3 (tr)
ES (1) ES2180935T3 (tr)
HU (1) HUP9902157A3 (tr)
ID (1) ID17294A (tr)
IL (1) IL126202A0 (tr)
PL (1) PL329739A1 (tr)
PT (1) PT902785E (tr)
TR (1) TR199802163T2 (tr)
WO (1) WO1997041111A1 (tr)
YU (1) YU16297A (tr)
ZA (1) ZA973696B (tr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6197798B1 (en) 1998-07-21 2001-03-06 Novartis Ag Amino-benzocycloalkane derivatives
IL139449A0 (en) * 1999-11-10 2001-11-25 Pfizer Prod Inc Use of apo b secretion/mtp inhibitors
CA2324800A1 (en) * 1999-11-10 2001-05-10 Mary Anne Hickman Use of apo b secretion/mtp inhibitors
IL139450A0 (en) * 1999-11-10 2001-11-25 Pfizer Prod Inc Methods of administering apo b-secretion/mtp inhibitors
CA2324801A1 (en) * 1999-11-10 2001-05-10 Andrew Gordon Swick Use of apo b secretion/mtp inhibitors and anti-obesity agents
US6878707B2 (en) * 2000-01-18 2005-04-12 Novartis Ag Carboxamides useful as inhibitors of microsomal triglyceride transfer protein and of apolipoprotein b secretion
WO2002014277A1 (fr) * 2000-08-10 2002-02-21 Tanabe Seiyaku Co., Ltd. Composes de biphenylcarboxamidoisoindoline, procedes de preparation de ceux-ci et produits intermediaires destines a la synthese de ceux-ci
WO2002014276A1 (fr) * 2000-08-10 2002-02-21 Tanabe Seiyaku Co., Ltd. Composes a base de benzoylaminoisoindoline, leurs procedes de preparation et produits intermediaires utilises dans leur synthese
CA2558766A1 (en) 2004-03-05 2005-09-22 The Trustees Of The University Of Pennsylvania The use of mtp inhibitors for treating disorders or diseases associated with hyperlipidemia and hypercholesterolemia while minimizing side effects
WO2008075949A1 (en) * 2006-12-20 2008-06-26 Friesland Brands B.V. Modulation of human microsomal triglyceride transfer protein (mtp or mttp) gene expression by food-grade/ingested dietary microorganisms

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2091102C (en) * 1992-03-06 2009-05-26 John R. Ii Wetterau Microsomal triglyceride transfer protein
US5595872A (en) * 1992-03-06 1997-01-21 Bristol-Myers Squibb Company Nucleic acids encoding microsomal trigyceride transfer protein
IL110172A (en) * 1993-07-22 2001-10-31 Lilly Co Eli Bicycle compounds and pharmaceuticals containing them
US5919795A (en) * 1995-06-07 1999-07-06 Pfizer Inc. Biphenyl-2-carboxylic acid-tetrahydro-isoquinolin-6-yl amide derivatives, their preparation and their use as inhibitors of microsomal triglyceride transfer protein and/or apolipoprotein B (Apo B) secretion
EP0832069B1 (en) * 1995-06-07 2003-03-05 Pfizer Inc. BIPHENYL-2-CARBOXYLIC ACID-TETRAHYDRO-ISOQUINOLIN-6-YL AMIDE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS INHIBITORS OF MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN AND/OR APOLIPOPROTEIN B (Apo B) SECRETION

Also Published As

Publication number Publication date
HUP9902157A2 (hu) 2000-04-28
HUP9902157A3 (en) 2000-07-28
CA2252621A1 (en) 1997-11-06
KR20000065152A (ko) 2000-11-06
DK0902785T3 (da) 2002-10-07
EP0902785A1 (en) 1999-03-24
CN1216988A (zh) 1999-05-19
DE69715188D1 (de) 2002-10-10
PT902785E (pt) 2002-12-31
ATE223400T1 (de) 2002-09-15
AU2226697A (en) 1997-11-19
ES2180935T3 (es) 2003-02-16
WO1997041111A1 (en) 1997-11-06
PL329739A1 (en) 1999-04-12
BR9709137A (pt) 1999-08-03
AU711279B2 (en) 1999-10-07
EP0902785B1 (en) 2002-09-04
YU16297A (sh) 1999-09-27
CA2252621C (en) 2002-09-03
US5998623A (en) 1999-12-07
IL126202A0 (en) 1999-05-09
AR006876A1 (es) 1999-09-29
ID17294A (id) 1997-12-18
ZA973696B (en) 1998-10-29
JPH11507959A (ja) 1999-07-13
CZ346498A3 (cs) 1999-09-15
DE69715188T2 (de) 2003-01-02

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