HUP9902157A3 - Process and intermediates for preparing 4'trifluoromethylbiphenyl-2-carboxylic acid [2-(2h-[1,2,4]triazol-3-ylmethyl)-1,2,3,4-tetrahydro-isoquinolin-6-yl]-amide - Google Patents

Process and intermediates for preparing 4'trifluoromethylbiphenyl-2-carboxylic acid [2-(2h-[1,2,4]triazol-3-ylmethyl)-1,2,3,4-tetrahydro-isoquinolin-6-yl]-amide

Info

Publication number
HUP9902157A3
HUP9902157A3 HU9902157A HUP9902157A HUP9902157A3 HU P9902157 A3 HUP9902157 A3 HU P9902157A3 HU 9902157 A HU9902157 A HU 9902157A HU P9902157 A HUP9902157 A HU P9902157A HU P9902157 A3 HUP9902157 A3 HU P9902157A3
Authority
HU
Hungary
Prior art keywords
trifluoromethylbiphenyl
isoquinolin
triazol
ylmethyl
tetrahydro
Prior art date
Application number
HU9902157A
Other languages
English (en)
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of HUP9902157A2 publication Critical patent/HUP9902157A2/hu
Publication of HUP9902157A3 publication Critical patent/HUP9902157A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
HU9902157A 1996-04-30 1997-03-13 Process and intermediates for preparing 4'trifluoromethylbiphenyl-2-carboxylic acid [2-(2h-[1,2,4]triazol-3-ylmethyl)-1,2,3,4-tetrahydro-isoquinolin-6-yl]-amide HUP9902157A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US1649596P 1996-04-30 1996-04-30

Publications (2)

Publication Number Publication Date
HUP9902157A2 HUP9902157A2 (hu) 2000-04-28
HUP9902157A3 true HUP9902157A3 (en) 2000-07-28

Family

ID=21777423

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9902157A HUP9902157A3 (en) 1996-04-30 1997-03-13 Process and intermediates for preparing 4'trifluoromethylbiphenyl-2-carboxylic acid [2-(2h-[1,2,4]triazol-3-ylmethyl)-1,2,3,4-tetrahydro-isoquinolin-6-yl]-amide

Country Status (23)

Country Link
US (1) US5998623A (hu)
EP (1) EP0902785B1 (hu)
JP (1) JPH11507959A (hu)
KR (1) KR20000065152A (hu)
CN (1) CN1216988A (hu)
AR (1) AR006876A1 (hu)
AT (1) ATE223400T1 (hu)
AU (1) AU711279B2 (hu)
BR (1) BR9709137A (hu)
CA (1) CA2252621C (hu)
CZ (1) CZ346498A3 (hu)
DE (1) DE69715188T2 (hu)
DK (1) DK0902785T3 (hu)
ES (1) ES2180935T3 (hu)
HU (1) HUP9902157A3 (hu)
ID (1) ID17294A (hu)
IL (1) IL126202A0 (hu)
PL (1) PL329739A1 (hu)
PT (1) PT902785E (hu)
TR (1) TR199802163T2 (hu)
WO (1) WO1997041111A1 (hu)
YU (1) YU16297A (hu)
ZA (1) ZA973696B (hu)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6197798B1 (en) 1998-07-21 2001-03-06 Novartis Ag Amino-benzocycloalkane derivatives
IL139450A0 (en) * 1999-11-10 2001-11-25 Pfizer Prod Inc Methods of administering apo b-secretion/mtp inhibitors
CA2324801A1 (en) * 1999-11-10 2001-05-10 Andrew Gordon Swick Use of apo b secretion/mtp inhibitors and anti-obesity agents
IL139449A0 (en) * 1999-11-10 2001-11-25 Pfizer Prod Inc Use of apo b secretion/mtp inhibitors
CA2324800A1 (en) * 1999-11-10 2001-05-10 Mary Anne Hickman Use of apo b secretion/mtp inhibitors
PT1259484E (pt) * 2000-01-18 2005-09-30 Novartis Ag Carboxamidas uteis como inibidores de proteina de transferencia de triglicerido microsomal e de secrecao de apolipoproteina b
AU2001277728A1 (en) * 2000-08-10 2002-02-25 Tanabe Seiyaku Co., Ltd. Biphenylcarboxamidoisoindoline compounds, processes for the preparation of the same and intermediates for the synthesis thereof
AU2001277727A1 (en) * 2000-08-10 2002-02-25 Tanabe Seiyaku Co., Ltd. Benzoylaminoisoindoline compounds, processes for the preparation of the same andintermediates for the synthesis thereof
ES2399721T5 (es) 2004-03-05 2016-05-25 Univ Pennsylvania Métodos para tratar trastornos o enfermedades asociados a la hiperlipidemia e hipercolesterolemia minimizando los efectos adversos
WO2008075949A1 (en) * 2006-12-20 2008-06-26 Friesland Brands B.V. Modulation of human microsomal triglyceride transfer protein (mtp or mttp) gene expression by food-grade/ingested dietary microorganisms

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU218419B (hu) * 1992-03-06 2000-08-28 E.R. Squibb And Sons, Inc. Mikroszomális triglicerid transzfer protein (MTP) nagy molekulatömegű alegységének rekombináns úton történő előállítására és a protein és inhibitorainak kimutatására szolgáló eljárások
US5595872A (en) * 1992-03-06 1997-01-21 Bristol-Myers Squibb Company Nucleic acids encoding microsomal trigyceride transfer protein
IL110172A (en) * 1993-07-22 2001-10-31 Lilly Co Eli Bicycle compounds and pharmaceuticals containing them
DK0832069T3 (da) * 1995-06-07 2003-04-22 Pfizer Biphenyl-2-carboxylsyre-tetrahydroisoquinolin-6-ylamidderivater, deres fremstilling og deres anvendelse som inhibitorer af sekretion af mikrosomalt triglyceridoverførselsprotein og/eller apolipoprotein B (Apo B)
EP0832069B1 (en) * 1995-06-07 2003-03-05 Pfizer Inc. BIPHENYL-2-CARBOXYLIC ACID-TETRAHYDRO-ISOQUINOLIN-6-YL AMIDE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS INHIBITORS OF MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN AND/OR APOLIPOPROTEIN B (Apo B) SECRETION

Also Published As

Publication number Publication date
PT902785E (pt) 2002-12-31
IL126202A0 (en) 1999-05-09
JPH11507959A (ja) 1999-07-13
AR006876A1 (es) 1999-09-29
ID17294A (id) 1997-12-18
EP0902785A1 (en) 1999-03-24
DK0902785T3 (da) 2002-10-07
YU16297A (sh) 1999-09-27
HUP9902157A2 (hu) 2000-04-28
BR9709137A (pt) 1999-08-03
DE69715188T2 (de) 2003-01-02
ES2180935T3 (es) 2003-02-16
CN1216988A (zh) 1999-05-19
CZ346498A3 (cs) 1999-09-15
KR20000065152A (ko) 2000-11-06
ZA973696B (en) 1998-10-29
PL329739A1 (en) 1999-04-12
CA2252621A1 (en) 1997-11-06
TR199802163T2 (xx) 1999-02-22
DE69715188D1 (de) 2002-10-10
US5998623A (en) 1999-12-07
AU2226697A (en) 1997-11-19
AU711279B2 (en) 1999-10-07
CA2252621C (en) 2002-09-03
EP0902785B1 (en) 2002-09-04
ATE223400T1 (de) 2002-09-15
WO1997041111A1 (en) 1997-11-06

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