IL126202A0 - Processes and intermediates for preparing 4'-trifluoromethylbiphenyl-2-carboxylic acid [2-(2H-[1,2,4]triazol-3-ylmethyl)-1,2,3,4-tetrahydro-isoquinolin-6-yl]-amide - Google Patents

Processes and intermediates for preparing 4'-trifluoromethylbiphenyl-2-carboxylic acid [2-(2H-[1,2,4]triazol-3-ylmethyl)-1,2,3,4-tetrahydro-isoquinolin-6-yl]-amide

Info

Publication number
IL126202A0
IL126202A0 IL12620297A IL12620297A IL126202A0 IL 126202 A0 IL126202 A0 IL 126202A0 IL 12620297 A IL12620297 A IL 12620297A IL 12620297 A IL12620297 A IL 12620297A IL 126202 A0 IL126202 A0 IL 126202A0
Authority
IL
Israel
Prior art keywords
trifluoromethylbiphenyl
isoquinolin
triazol
ylmethyl
tetrahydro
Prior art date
Application number
IL12620297A
Other languages
English (en)
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of IL126202A0 publication Critical patent/IL126202A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
IL12620297A 1996-04-30 1997-03-13 Processes and intermediates for preparing 4'-trifluoromethylbiphenyl-2-carboxylic acid [2-(2H-[1,2,4]triazol-3-ylmethyl)-1,2,3,4-tetrahydro-isoquinolin-6-yl]-amide IL126202A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1649596P 1996-04-30 1996-04-30
PCT/IB1997/000254 WO1997041111A1 (en) 1996-04-30 1997-03-13 Processes and intermediates for preparing 4'-trifluoromethylbiphenyl-2-carboxylic acid [2-(2h-[1,2,4]triazol-3-ylmethyl)-1,2,3,4-tetrahydro-isoquinolin-6-yl]-amide

Publications (1)

Publication Number Publication Date
IL126202A0 true IL126202A0 (en) 1999-05-09

Family

ID=21777423

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12620297A IL126202A0 (en) 1996-04-30 1997-03-13 Processes and intermediates for preparing 4'-trifluoromethylbiphenyl-2-carboxylic acid [2-(2H-[1,2,4]triazol-3-ylmethyl)-1,2,3,4-tetrahydro-isoquinolin-6-yl]-amide

Country Status (23)

Country Link
US (1) US5998623A (xx)
EP (1) EP0902785B1 (xx)
JP (1) JPH11507959A (xx)
KR (1) KR20000065152A (xx)
CN (1) CN1216988A (xx)
AR (1) AR006876A1 (xx)
AT (1) ATE223400T1 (xx)
AU (1) AU711279B2 (xx)
BR (1) BR9709137A (xx)
CA (1) CA2252621C (xx)
CZ (1) CZ346498A3 (xx)
DE (1) DE69715188T2 (xx)
DK (1) DK0902785T3 (xx)
ES (1) ES2180935T3 (xx)
HU (1) HUP9902157A3 (xx)
ID (1) ID17294A (xx)
IL (1) IL126202A0 (xx)
PL (1) PL329739A1 (xx)
PT (1) PT902785E (xx)
TR (1) TR199802163T2 (xx)
WO (1) WO1997041111A1 (xx)
YU (1) YU16297A (xx)
ZA (1) ZA973696B (xx)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6197798B1 (en) 1998-07-21 2001-03-06 Novartis Ag Amino-benzocycloalkane derivatives
IL139450A0 (en) * 1999-11-10 2001-11-25 Pfizer Prod Inc Methods of administering apo b-secretion/mtp inhibitors
CA2324801A1 (en) * 1999-11-10 2001-05-10 Andrew Gordon Swick Use of apo b secretion/mtp inhibitors and anti-obesity agents
IL139449A0 (en) * 1999-11-10 2001-11-25 Pfizer Prod Inc Use of apo b secretion/mtp inhibitors
CA2324800A1 (en) * 1999-11-10 2001-05-10 Mary Anne Hickman Use of apo b secretion/mtp inhibitors
PT1259484E (pt) * 2000-01-18 2005-09-30 Novartis Ag Carboxamidas uteis como inibidores de proteina de transferencia de triglicerido microsomal e de secrecao de apolipoproteina b
AU2001277728A1 (en) * 2000-08-10 2002-02-25 Tanabe Seiyaku Co., Ltd. Biphenylcarboxamidoisoindoline compounds, processes for the preparation of the same and intermediates for the synthesis thereof
AU2001277727A1 (en) * 2000-08-10 2002-02-25 Tanabe Seiyaku Co., Ltd. Benzoylaminoisoindoline compounds, processes for the preparation of the same andintermediates for the synthesis thereof
ES2399721T5 (es) 2004-03-05 2016-05-25 Univ Pennsylvania Métodos para tratar trastornos o enfermedades asociados a la hiperlipidemia e hipercolesterolemia minimizando los efectos adversos
WO2008075949A1 (en) * 2006-12-20 2008-06-26 Friesland Brands B.V. Modulation of human microsomal triglyceride transfer protein (mtp or mttp) gene expression by food-grade/ingested dietary microorganisms

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU218419B (hu) * 1992-03-06 2000-08-28 E.R. Squibb And Sons, Inc. Mikroszomális triglicerid transzfer protein (MTP) nagy molekulatömegű alegységének rekombináns úton történő előállítására és a protein és inhibitorainak kimutatására szolgáló eljárások
US5595872A (en) * 1992-03-06 1997-01-21 Bristol-Myers Squibb Company Nucleic acids encoding microsomal trigyceride transfer protein
IL110172A (en) * 1993-07-22 2001-10-31 Lilly Co Eli Bicycle compounds and pharmaceuticals containing them
DK0832069T3 (da) * 1995-06-07 2003-04-22 Pfizer Biphenyl-2-carboxylsyre-tetrahydroisoquinolin-6-ylamidderivater, deres fremstilling og deres anvendelse som inhibitorer af sekretion af mikrosomalt triglyceridoverførselsprotein og/eller apolipoprotein B (Apo B)
EP0832069B1 (en) * 1995-06-07 2003-03-05 Pfizer Inc. BIPHENYL-2-CARBOXYLIC ACID-TETRAHYDRO-ISOQUINOLIN-6-YL AMIDE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS INHIBITORS OF MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN AND/OR APOLIPOPROTEIN B (Apo B) SECRETION

Also Published As

Publication number Publication date
PT902785E (pt) 2002-12-31
JPH11507959A (ja) 1999-07-13
AR006876A1 (es) 1999-09-29
ID17294A (id) 1997-12-18
EP0902785A1 (en) 1999-03-24
DK0902785T3 (da) 2002-10-07
YU16297A (sh) 1999-09-27
HUP9902157A2 (hu) 2000-04-28
HUP9902157A3 (en) 2000-07-28
BR9709137A (pt) 1999-08-03
DE69715188T2 (de) 2003-01-02
ES2180935T3 (es) 2003-02-16
CN1216988A (zh) 1999-05-19
CZ346498A3 (cs) 1999-09-15
KR20000065152A (ko) 2000-11-06
ZA973696B (en) 1998-10-29
PL329739A1 (en) 1999-04-12
CA2252621A1 (en) 1997-11-06
TR199802163T2 (xx) 1999-02-22
DE69715188D1 (de) 2002-10-10
US5998623A (en) 1999-12-07
AU2226697A (en) 1997-11-19
AU711279B2 (en) 1999-10-07
CA2252621C (en) 2002-09-03
EP0902785B1 (en) 2002-09-04
ATE223400T1 (de) 2002-09-15
WO1997041111A1 (en) 1997-11-06

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