DK0852580T3 - Fremgangsmåde til fremstilling af dihydroxypyrimidin-derivater - Google Patents
Fremgangsmåde til fremstilling af dihydroxypyrimidin-derivaterInfo
- Publication number
- DK0852580T3 DK0852580T3 DK96930988T DK96930988T DK0852580T3 DK 0852580 T3 DK0852580 T3 DK 0852580T3 DK 96930988 T DK96930988 T DK 96930988T DK 96930988 T DK96930988 T DK 96930988T DK 0852580 T3 DK0852580 T3 DK 0852580T3
- Authority
- DK
- Denmark
- Prior art keywords
- preparation
- dihydroxypyrimidine
- derivatives
- dihydroxypyrimidine derivatives
- general formula
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/52—Two oxygen atoms
- C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/02—Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH247495 | 1995-08-31 | ||
| PCT/EP1996/003826 WO1997008152A1 (de) | 1995-08-31 | 1996-08-30 | Verfahren zur herstellung von dihydroxypyrimidin-derivaten |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0852580T3 true DK0852580T3 (da) | 2000-11-20 |
Family
ID=4234620
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK96930988T DK0852580T3 (da) | 1995-08-31 | 1996-08-30 | Fremgangsmåde til fremstilling af dihydroxypyrimidin-derivater |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US6248571B1 (da) |
| EP (1) | EP0852580B1 (da) |
| JP (1) | JP2000507911A (da) |
| AT (1) | ATE197150T1 (da) |
| AU (1) | AU6985796A (da) |
| CA (1) | CA2227949A1 (da) |
| DE (1) | DE59606057D1 (da) |
| DK (1) | DK0852580T3 (da) |
| ES (1) | ES2152563T3 (da) |
| PT (1) | PT852580E (da) |
| WO (1) | WO1997008152A1 (da) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10140269A1 (de) | 2001-08-16 | 2003-02-27 | Degussa | Verfahren zur Herstellung von 4,6-Dihydroxypyrimidin |
| US7405192B2 (en) | 2001-10-31 | 2008-07-29 | Alcon, Inc. | Bone morphogenic proteins (BMP), BMP receptors and BMP binding proteins and their use in the diagnosis and treatment of glaucoma |
| US20030143601A1 (en) * | 2001-11-16 | 2003-07-31 | Hansen Thomas R. | Methods and compositions for the detection of bovine pregnancy which utilize members of the 1-8 family of interferon inducible genes |
| RS20050532A (en) | 2003-01-14 | 2007-12-31 | Arena Pharmaceuticals Inc., | 1,2,3-trisubstituted aryl and heteroaryl derivatives as modulators of metabolism and the prpphylaxis and treatment of disorders related thereto such as diabetes and hyperglycemia |
| AR045047A1 (es) | 2003-07-11 | 2005-10-12 | Arena Pharm Inc | Derivados arilo y heteroarilo trisustituidos como moduladores del metabolismo y de la profilaxis y tratamiento de desordenes relacionados con los mismos |
| US7854756B2 (en) | 2004-01-22 | 2010-12-21 | Boston Scientific Scimed, Inc. | Medical devices |
| SG188548A1 (en) | 2010-09-22 | 2013-04-30 | Arena Pharm Inc | Modulators of the gpr119 receptor and the treatment of disorders related thereto |
| CZ305457B6 (cs) | 2011-02-28 | 2015-09-30 | Ústav organické chemie a biochemie, Akademie věd ČR v. v. i. | Pyrimidinové sloučeniny inhibující tvorbu oxidu dusnatého a prostaglandinu E2, způsob výroby a použití |
| CN102442954B (zh) * | 2011-09-06 | 2014-01-08 | 淄博万昌科技股份有限公司 | 利用丙烯腈副产氢氰酸制备4，6-二羟基嘧啶的方法 |
| NZ734220A (en) | 2015-01-06 | 2022-01-28 | Arena Pharm Inc | Methods of treating conditions related to the s1p1 receptor |
| CN108349891B (zh) | 2015-06-22 | 2022-04-05 | 艾尼纳制药公司 | 用于s1p1受体相关病症的化合物的结晶l-精氨酸盐 |
| EP3902790B1 (de) * | 2018-12-28 | 2024-04-03 | Saltigo GmbH | Verbessertes verfahren zur herstellung von 4,6-dihydroxypyrimidin |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3306900A (en) * | 1964-02-21 | 1967-02-28 | Kyowa Hakko Kogyo Kk | Method for producing 4,6-dihydroxy-pyrimidine |
| FR1424940A (fr) * | 1964-02-21 | 1966-01-14 | Kyowa Hakko Kogyo Kk | Procédé de production de la 4, 6-dihydroxypyrimidine |
| JPH06256278A (ja) * | 1993-03-03 | 1994-09-13 | Nissan Chem Ind Ltd | 光学活性α−カルバモイルアルカン酸誘導体およびその製法 |
| JPH0799983A (ja) * | 1993-10-05 | 1995-04-18 | Nippon Kayaku Co Ltd | 微生物によるｐ−ニトロベンジルアルコールマロン酸モノエステルの製造方法 |
-
1996
- 1996-08-30 ES ES96930988T patent/ES2152563T3/es not_active Expired - Lifetime
- 1996-08-30 DE DE59606057T patent/DE59606057D1/de not_active Expired - Fee Related
- 1996-08-30 AU AU69857/96A patent/AU6985796A/en not_active Abandoned
- 1996-08-30 DK DK96930988T patent/DK0852580T3/da active
- 1996-08-30 JP JP9509864A patent/JP2000507911A/ja active Pending
- 1996-08-30 PT PT96930988T patent/PT852580E/pt unknown
- 1996-08-30 AT AT96930988T patent/ATE197150T1/de not_active IP Right Cessation
- 1996-08-30 WO PCT/EP1996/003826 patent/WO1997008152A1/de active IP Right Grant
- 1996-08-30 CA CA002227949A patent/CA2227949A1/en not_active Abandoned
- 1996-08-30 US US09/029,230 patent/US6248571B1/en not_active Expired - Fee Related
- 1996-08-30 EP EP96930988A patent/EP0852580B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| AU6985796A (en) | 1997-03-19 |
| EP0852580B1 (de) | 2000-10-25 |
| CA2227949A1 (en) | 1997-03-06 |
| ATE197150T1 (de) | 2000-11-15 |
| PT852580E (pt) | 2001-02-28 |
| US6248571B1 (en) | 2001-06-19 |
| EP0852580A1 (de) | 1998-07-15 |
| DE59606057D1 (de) | 2000-11-30 |
| WO1997008152A1 (de) | 1997-03-06 |
| ES2152563T3 (es) | 2001-02-01 |
| JP2000507911A (ja) | 2000-06-27 |
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