TR199701647A3 - Ikame edilmis purin türevleri,bunlarin imalat usulü - Google Patents

Ikame edilmis purin türevleri,bunlarin imalat usulü

Info

Publication number
TR199701647A3
TR199701647A3 TR97/01647A TR9701647A TR199701647A3 TR 199701647 A3 TR199701647 A3 TR 199701647A3 TR 97/01647 A TR97/01647 A TR 97/01647A TR 9701647 A TR9701647 A TR 9701647A TR 199701647 A3 TR199701647 A3 TR 199701647A3
Authority
TR
Turkey
Prior art keywords
manufacture
purine derivatives
substituted purine
substituted
derivatives
Prior art date
Application number
TR97/01647A
Other languages
English (en)
Other versions
TR199701647A2 (tr
Inventor
Peyman Dr.Anuschirwan
Knolle Dr.Jochen
Wehner Dr.Volkmar
Breipohl Dr.Gerhard
Gourvest Dr.Jean-Francois
Carniato Dr.Denis
Richard Gadek Dr.Thomas
Original Assignee
Hoechst Aktiengesellschaft
Genentech,Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Aktiengesellschaft, Genentech,Inc. filed Critical Hoechst Aktiengesellschaft
Publication of TR199701647A3 publication Critical patent/TR199701647A3/tr
Publication of TR199701647A2 publication Critical patent/TR199701647A2/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
    • C07D473/34—Nitrogen atom attached in position 6, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
TR97/01647A 1996-12-20 1997-12-18 Ikame edilmis purin türevleri,bunlarin imalat usulü TR199701647A2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19653646A DE19653646A1 (de) 1996-12-20 1996-12-20 Substituierte Purinderivate, Verfahren zu deren Herstellung, sie enthaltende Mittel und deren Verwendung

Publications (2)

Publication Number Publication Date
TR199701647A3 true TR199701647A3 (tr) 1998-07-21
TR199701647A2 TR199701647A2 (tr) 1998-07-21

Family

ID=7815761

Family Applications (1)

Application Number Title Priority Date Filing Date
TR97/01647A TR199701647A2 (tr) 1996-12-20 1997-12-18 Ikame edilmis purin türevleri,bunlarin imalat usulü

Country Status (22)

Country Link
EP (1) EP0853084B1 (tr)
JP (1) JP4620190B2 (tr)
KR (1) KR19980064655A (tr)
CN (2) CN1495184A (tr)
AR (1) AR010700A1 (tr)
AT (1) ATE404562T1 (tr)
AU (1) AU728865B2 (tr)
BR (1) BR9706387A (tr)
CA (1) CA2225366C (tr)
CZ (1) CZ294437B6 (tr)
DE (2) DE19653646A1 (tr)
HK (1) HK1012190A1 (tr)
HU (1) HUP9702507A3 (tr)
ID (1) ID19254A (tr)
IL (1) IL122642A0 (tr)
NO (1) NO314583B1 (tr)
NZ (1) NZ329431A (tr)
PL (1) PL323969A1 (tr)
RU (1) RU2228335C2 (tr)
TR (1) TR199701647A2 (tr)
TW (1) TW523515B (tr)
ZA (1) ZA9711317B (tr)

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CN1140511C (zh) 1998-04-09 2004-03-03 明治制果株式会社 作为整合素αvβ3拮抗剂的氨基哌啶衍生物
PL349216A1 (en) 1998-12-23 2002-07-01 Searle & Co Method of using a cyclooxygenase-2 inhibitor and a matrix metalloproteinase inhibitor as a combination therapy in the treatment of neoplasia
JP3270834B2 (ja) 1999-01-27 2002-04-02 ファイザー・プロダクツ・インク 抗がん剤として有用なヘテロ芳香族二環式誘導体
UA71945C2 (en) 1999-01-27 2005-01-17 Pfizer Prod Inc Substituted bicyclic derivatives being used as anticancer agents
EP1065207A1 (en) * 1999-07-02 2001-01-03 Aventis Pharma Deutschland GmbH Naphthyridine derivatives, processes for their preparation, their use, and pharmaceutical compositions comprising them
EP1065208A1 (en) * 1999-07-02 2001-01-03 Aventis Pharma Deutschland GmbH Substituted purine derivatives as inhibitors of cell adhesion
AU6316900A (en) 1999-08-05 2001-03-05 Meiji Seika Kaisha Ltd. Omega-amino-alpha-hydroxycarboxylic acid derivatives having integrin alphavbeta3antagonism
EP1176145A1 (en) * 2000-07-28 2002-01-30 Aventis Pharma Deutschland GmbH Novel guanidino derivatives as inhibitors of cell adhesion
DE10042655A1 (de) 2000-08-31 2002-03-14 Aventis Pharma Gmbh Verfahren zur Herstellung von Inhibitoren der Zell-Adhäsion
KR100438820B1 (ko) * 2001-03-05 2004-07-05 삼성코닝 주식회사 Ιιι-ⅴ족 화합물 반도체 기판의 제조 방법
CN1247258C (zh) 2001-04-24 2006-03-29 默克专利有限公司 使用抗血管生成剂和TNFα的联合疗法
FR2847254B1 (fr) * 2002-11-19 2005-01-28 Aventis Pharma Sa Nouveaux derives antagonistes du recepteur de la vitronectine, leur procede de preparation, leur application comme medicaments et les compositions pharmaceutiques les refermant
FR2870541B1 (fr) * 2004-05-18 2006-07-14 Proskelia Sas Derives de pyrimidines antigonistes du recepteur de la vitronectine
UA87854C2 (en) 2004-06-07 2009-08-25 Мерк Энд Ко., Инк. N-(2-benzyl)-2-phenylbutanamides as androgen receptor modulators
US20090130098A1 (en) 2006-01-18 2009-05-21 Merck Patent Gmbh Specific therapy using integrin ligands for treating cancer
ES2399159T3 (es) 2007-01-18 2013-03-26 Merck Patent Gmbh Terapia y medicamento específicos usando ligandos de integrinas para el tratamiento del cáncer
SI2206727T1 (sl) 2007-10-11 2015-06-30 Daiichi Sankyo Company, Limited Protitelo, ki cilja osteoklast - soroden protein Siglec-15
CN101909440A (zh) * 2007-11-14 2010-12-08 瑞科西有限公司 治疗用化合物及其在治疗疾病和障碍中的用途
NZ605450A (en) 2009-04-09 2014-07-25 Daiichi Sankyo Co Ltd Anti-siglec-15 antibody
SG176103A1 (en) 2009-05-25 2011-12-29 Merck Patent Gmbh Continuous administration of cilengitide in cancer treatments
MX2013003828A (es) 2010-10-05 2013-06-28 Daiichi Sankyo Co Ltd Anticuerpo dirigido a la proteina lectina tipo inmunoglobulina de union a acido sialico-15 relacionada con osteoclastos.
EP2832857B1 (en) 2012-03-30 2018-01-03 Daiichi Sankyo Company, Limited Cdr-modified anti-siglec-15 antibody
CN103665043B (zh) 2012-08-30 2017-11-10 江苏豪森药业集团有限公司 一种替诺福韦前药及其在医药上的应用
EP3148587B1 (en) 2014-05-30 2021-02-24 Pfizer Inc Carbonitrile derivatives as selective androgen receptor modulators
WO2023275715A1 (en) 2021-06-30 2023-01-05 Pfizer Inc. Metabolites of selective androgen receptor modulators

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JPS4730696Y1 (tr) * 1966-12-10 1972-09-13
JPS6396663A (ja) * 1986-10-13 1988-04-27 Mita Ind Co Ltd 静電荷像現像用トナ−
JPS6396553A (ja) * 1986-10-14 1988-04-27 Sekisui Chem Co Ltd 充填剤
DE4129603A1 (de) * 1991-09-06 1993-03-11 Thomae Gmbh Dr K Kondensierte 5-gliedrige heterocyclen, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
MX9207334A (es) * 1991-12-18 1993-08-01 Glaxo Inc Acidos nucleicos peptidicos y formulacion farma- ceutica que los contiene
FR2700337B1 (fr) * 1993-01-11 1995-04-14 Lafon Labor Dérivés d'imidazopyridine-2-one, leur procédé de préparation et leur utilisation en thérapeutique.
US6133444A (en) * 1993-12-22 2000-10-17 Perseptive Biosystems, Inc. Synthons for the synthesis and deprotection of peptide nucleic acids under mild conditions
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US5929046A (en) * 1994-06-08 1999-07-27 Cancer Research Campaign Technology Limited Pyrimidine and purine derivatives and their use in treating tumour cells
US5994361A (en) * 1994-06-22 1999-11-30 Biochem Pharma Substituted purinyl derivatives with immunomodulating activity
CA2193966A1 (en) * 1994-06-29 1996-01-11 Fadia El-Fehail Ali Vitronectin receptor antagonists
US5525606A (en) * 1994-08-01 1996-06-11 The United States Of America As Represented By The Department Of Health And Human Services Substituted 06-benzylguanines and 6(4)-benzyloxypyrimidines
WO1996020212A2 (en) * 1994-12-28 1996-07-04 Buchardt, Dorte Peptide nucleic acid incorporating a chiral backbone
US5977061A (en) * 1995-04-21 1999-11-02 Institute Of Organic Chemistry And Biochemistry Of The Academy Of Sciences Of The Czech Republic N6 - substituted nucleotide analagues and their use
DE69632324T2 (de) * 1995-06-07 2005-06-16 PerSeptive Biosystems, Inc., Framingham Pna-dna-chimäre und pna-synthone zu deren herstellung
JPH1025294A (ja) * 1996-03-26 1998-01-27 Akira Matsuda 縮合ヘテロ環誘導体、その製造法及びそれを含有する悪性腫瘍治療剤
CA2249598A1 (en) * 1996-03-26 1997-10-02 Paul Joseph Gilligan Aryloxy- and arylthio-fused pyridines and pyrimidines and derivatives
GB9613021D0 (en) * 1996-06-21 1996-08-28 Pharmacia Spa Bicyclic 4-aralkylaminopyrimidine derivatives as tyrosine kinase inhibitors
ATE311402T1 (de) * 1996-07-24 2005-12-15 Buchardt Dorte Peptidnukleinsäuren mit erhöhter bindungsaffinität, sequenzspezifität und löslichkeit
US5866702A (en) * 1996-08-02 1999-02-02 Cv Therapeutics, Incorporation Purine inhibitors of cyclin dependent kinase 2

Also Published As

Publication number Publication date
HUP9702507A3 (en) 1999-12-28
CZ294437B6 (cs) 2005-01-12
ATE404562T1 (de) 2008-08-15
IL122642A0 (en) 1998-08-16
JP4620190B2 (ja) 2011-01-26
JPH10182645A (ja) 1998-07-07
BR9706387A (pt) 2000-03-14
EP0853084A2 (de) 1998-07-15
CZ411497A3 (cs) 1998-07-15
AU4846697A (en) 1998-06-25
TW523515B (en) 2003-03-11
HUP9702507A2 (hu) 1999-05-28
CA2225366A1 (en) 1998-06-20
CA2225366C (en) 2006-10-10
CN1495184A (zh) 2004-05-12
EP0853084B1 (de) 2008-08-13
NZ329431A (en) 2000-01-28
ZA9711317B (en) 1998-06-22
PL323969A1 (en) 1998-06-22
HK1012190A1 (en) 1999-07-30
TR199701647A2 (tr) 1998-07-21
CN1193623A (zh) 1998-09-23
HU9702507D0 (en) 1998-03-02
NO314583B1 (no) 2003-04-14
NO975977D0 (no) 1997-12-19
DE19653646A1 (de) 1998-06-25
NO975977L (no) 1998-06-22
EP0853084A3 (de) 1998-09-09
MX9710277A (es) 1998-10-31
KR19980064655A (ko) 1998-10-07
AU728865B2 (en) 2001-01-18
RU2228335C2 (ru) 2004-05-10
DE59712958D1 (de) 2008-09-25
CN1101816C (zh) 2003-02-19
AR010700A1 (es) 2000-06-28
ID19254A (id) 1998-06-28

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