TR199500884A2 - Biyolojik sun'i hücre-disi matris bilesimi ve yöntemleri. - Google Patents

Biyolojik sun'i hücre-disi matris bilesimi ve yöntemleri.

Info

Publication number
TR199500884A2
TR199500884A2 TR95/00884A TR9500884A TR199500884A2 TR 199500884 A2 TR199500884 A2 TR 199500884A2 TR 95/00884 A TR95/00884 A TR 95/00884A TR 9500884 A TR9500884 A TR 9500884A TR 199500884 A2 TR199500884 A2 TR 199500884A2
Authority
TR
Turkey
Prior art keywords
matrix
peptide fragment
nerve
cell adhesive
adhesive peptide
Prior art date
Application number
TR95/00884A
Other languages
English (en)
Inventor
Patrick Aebischer
Ravi Bellamkonda
John P Ranieri
Original Assignee
Cytotherapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cytotherapeutics Inc filed Critical Cytotherapeutics Inc
Publication of TR199500884A2 publication Critical patent/TR199500884A2/tr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/20—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/227—Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/52—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/005—Ingredients of undetermined constitution or reaction products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/043—Proteins; Polypeptides; Degradation products thereof
    • A61L31/047—Other specific proteins or polypeptides not covered by A61L31/044 - A61L31/046
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/32—Materials or treatment for tissue regeneration for nerve reconstruction
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/81—Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier
    • Y10S530/812—Peptides or proteins is immobilized on, or in, an organic carrier
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/81—Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier
    • Y10S530/812—Peptides or proteins is immobilized on, or in, an organic carrier
    • Y10S530/813—Carrier is a saccharide
TR95/00884A 1994-07-20 1995-08-20 Biyolojik sun'i hücre-disi matris bilesimi ve yöntemleri. TR199500884A2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/280,646 US5834029A (en) 1994-07-20 1994-07-20 Nerve guidance channel containing bioartificial three-dimensional hydrogel extracellular matrix derivatized with cell adhesive peptide fragment

Publications (1)

Publication Number Publication Date
TR199500884A2 true TR199500884A2 (tr) 1996-06-21

Family

ID=23073997

Family Applications (2)

Application Number Title Priority Date Filing Date
TR95/00883A TR199500883A2 (tr) 1994-07-20 1995-07-20 Biyolojik sun'i hücre-disi matris bilesimi ve yöntemleri.
TR95/00884A TR199500884A2 (tr) 1994-07-20 1995-08-20 Biyolojik sun'i hücre-disi matris bilesimi ve yöntemleri.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
TR95/00883A TR199500883A2 (tr) 1994-07-20 1995-07-20 Biyolojik sun'i hücre-disi matris bilesimi ve yöntemleri.

Country Status (14)

Country Link
US (2) US5834029A (tr)
EP (1) EP0772466B1 (tr)
JP (1) JPH10503098A (tr)
KR (1) KR970704481A (tr)
AT (1) ATE255425T1 (tr)
AU (1) AU3142395A (tr)
CA (1) CA2194493A1 (tr)
DE (1) DE69532240D1 (tr)
FI (1) FI970218A (tr)
IL (1) IL114672A (tr)
NO (1) NO970155L (tr)
TR (2) TR199500883A2 (tr)
WO (1) WO1996002286A1 (tr)
ZA (1) ZA956033B (tr)

Families Citing this family (143)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5834029A (en) * 1994-07-20 1998-11-10 Cytotherapeutics, Inc. Nerve guidance channel containing bioartificial three-dimensional hydrogel extracellular matrix derivatized with cell adhesive peptide fragment
US6294202B1 (en) * 1994-10-06 2001-09-25 Genzyme Corporation Compositions containing polyanionic polysaccharides and hydrophobic bioabsorbable polymers
US20050152950A1 (en) * 1995-11-13 2005-07-14 Saffran Bruce N. Method and apparatus for macromolecular delivery using a coated membrane
SE9601243D0 (sv) * 1996-03-29 1996-03-29 Hans Arne Hansson Promotion of regeneration of organized tissues
IL118376A0 (en) * 1996-05-22 1996-09-12 Univ Ben Gurion Polysaccharide sponges for cell culture and transplantation
SE9602879D0 (sv) * 1996-07-26 1996-07-26 Henrich Cheng Medical device
US6238429B1 (en) * 1997-05-05 2001-05-29 Medtronic, Inc. Biologic cabling
JP4988076B2 (ja) * 1997-05-22 2012-08-01 マイヤー，ヤールク ペプチド被覆インプラントおよびその調製方法
AU3097999A (en) * 1998-03-18 1999-10-11 University Of Pittsburgh Chitosan-based composite materials containing glycosaminoglycan for cartilage repair
US6171610B1 (en) 1998-04-24 2001-01-09 University Of Massachusetts Guided development and support of hydrogel-cell compositions
US6027744A (en) * 1998-04-24 2000-02-22 University Of Massachusetts Medical Center Guided development and support of hydrogel-cell compositions
US6593133B1 (en) * 1998-07-06 2003-07-15 Nsgene A/S Neurotrophic factors
US6592623B1 (en) 1999-08-31 2003-07-15 Virginia Commonwealth University Intellectual Property Foundation Engineered muscle
US6903244B1 (en) 1999-02-26 2005-06-07 University Of Utah Research Foundation Mice which are +/− or −/− for the elastin gene as models for vascular disease
US7560275B2 (en) * 1999-12-30 2009-07-14 Vbi Technologies, L.L.C. Compositions and methods for generating skin
US7575921B2 (en) * 1999-12-30 2009-08-18 Vbi Technologies, L.L.C. Spore-like cells and uses thereof
DE20019809U1 (de) * 2000-05-31 2001-07-12 Fraunhofer Ges Forschung Knorpelersatz und Biomatrix zur Kultivierung von Zellen
JP2002078792A (ja) * 2000-09-07 2002-03-19 Kuraray Co Ltd 神経再生用材料
DE10053611A1 (de) * 2000-10-28 2002-05-02 Inst Textil & Faserforschung Bioresorbierbare Nervenleitschiene
WO2002057428A1 (en) * 2000-10-30 2002-07-25 University Of Massachusetts Isolation of spore-like cells from tissues exposed to extreme conditions
AU2399502A (en) * 2000-11-14 2002-05-27 R Labs Bvi Nv Cross-linked hyaluronic acid-laminin gels and use thereof in cell culture and medical implants
US7442370B2 (en) * 2001-02-01 2008-10-28 Biogen Idec Ma Inc. Polymer conjugates of mutated neublastin
DE10105040A1 (de) * 2001-02-05 2002-08-14 Tell Pharm Ag Hergiswil Tripeptid-Derivate für die Behandlung von postläsionalen Krankheiten des Nervensystems
DE10105041A1 (de) * 2001-02-05 2002-08-14 Tell Pharm Ag Hergiswil Tripeptide und Tripeptid-Derivate für die Behandlung neurodegenerativer Krankheiten
US20050192228A1 (en) * 2001-02-05 2005-09-01 Jean Rapin Tripeptide derivatives for the treatment of neurodegenerative diseases
DE10105038B4 (de) * 2001-02-05 2005-07-07 Neurotell Ag Tripeptid-Derivate für die Behandlung von postläsionalen Krankheiten des Nervensystems
WO2002062961A2 (en) * 2001-02-06 2002-08-15 Massachusetts Institute Of Technology Peptide scaffold encapsulation of tissue cells and uses thereof
US7276580B2 (en) 2001-03-12 2007-10-02 Biogen Idec Ma Inc. Neurotrophic factors
US20040151705A1 (en) * 2002-03-22 2004-08-05 Shuichi Mizuno Neo-cartilage constructs and a method for preparation thereof
JP3871525B2 (ja) * 2001-04-26 2007-01-24 ニプロ株式会社 生体組織または器官再生用器具
US20030049839A1 (en) * 2001-08-01 2003-03-13 The University Of Texas System Transparent multi-channel cell scaffold that creates a cellular and/or molecular gradient
US6716225B2 (en) * 2001-08-02 2004-04-06 Collagen Matrix, Inc. Implant devices for nerve repair
WO2003030836A2 (en) * 2001-10-12 2003-04-17 Case Western Reserve University Neuronal regeneration
US7041506B2 (en) * 2001-11-19 2006-05-09 Becton Dickinson And Company Peptides promoting cell adherence, growth and secretion
AU2002351164A1 (en) * 2001-11-26 2003-06-10 Molecular Reflections, Inc. Microscale immobilization of molecules using a hydrogel and methods of use thereof
US7429267B2 (en) * 2001-12-04 2008-09-30 The Trustees Of The University Of Pennsylvania Device and method using integrated neuronal cells and an electronic device
KR100493461B1 (ko) * 2002-02-27 2005-06-07 재단법인서울대학교산학협력재단 접착분자가 부착된 천연고분자, 그의 제조방법 및 그의 용도
US8298606B2 (en) 2002-03-08 2012-10-30 The Regents Of The University Of California Methods and compositions for stabilizing the myocardium
US6932833B1 (en) * 2002-04-01 2005-08-23 Bobby W. Presley Method and barrier for limiting fluid movement through a tissue rent
US20070100358A2 (en) * 2002-08-01 2007-05-03 Texas Scottish Rite Hospital For Children A Biomimetic Synthetic Nerve Implant
WO2005046457A2 (en) * 2003-11-05 2005-05-26 Texas Scottish Rite Hospital For Children A biomimetic biosynthetic nerve implant
US20060034807A1 (en) * 2002-08-09 2006-02-16 Ottawa Health Research Institute Innervated artificial tissues and uses thereof
JP4571776B2 (ja) * 2002-11-05 2010-10-27 Ｊｘ日鉱日石エネルギー株式会社 潤滑油組成物
AU2002952993A0 (en) 2002-11-29 2002-12-12 The Corporation Of The Trustees Of The Order Of The Sisters Of Mercy In Queensland Therapeutic and diagnostic agents
JP4605985B2 (ja) * 2002-12-27 2011-01-05 ニプロ株式会社 神経再生誘導管
SI1594436T1 (sl) 2003-01-31 2011-01-31 Biogen Idec Inc Mutirani neoblastin
US20040156878A1 (en) * 2003-02-11 2004-08-12 Alireza Rezania Implantable medical device seeded with mammalian cells and methods of treatment
EP1618179B1 (en) 2003-04-18 2014-05-07 Biogen Idec MA Inc. Polymer-conjugated glycosylated neublastin
WO2005014784A2 (en) * 2003-06-20 2005-02-17 Tumer Tumay O System for molecular imaging
US8545386B2 (en) * 2003-08-14 2013-10-01 Boston Scientific Scimed, Inc. Surgical slings
WO2005020677A1 (en) 2003-08-29 2005-03-10 The Walter And Eliza Hall Institute Of Medical Research Method of selecting animal models from animals which have been subject to mutagenesis, and the use of myb transcription factors for screening
NZ547767A (en) 2003-12-24 2010-05-28 Inst Medical W & E Hall Therapeutic agents and uses therefor
US7709439B2 (en) * 2004-02-20 2010-05-04 Boston Scientific Scimed, Inc. Biomaterials for enhanced healing
US7840263B2 (en) 2004-02-27 2010-11-23 Cardiac Pacemakers, Inc. Method and apparatus for device controlled gene expression
GB0405045D0 (en) * 2004-03-05 2004-04-07 Spinox Ltd Composite materials
US20060134779A1 (en) * 2004-03-10 2006-06-22 Banes Albert J Modulation of cell intrinsic strain to control cell modulus, matrix synthesis, secretion, organization, material properties and remodeling of tissue engineered constructs
WO2005099758A2 (en) * 2004-04-17 2005-10-27 The Board Of Trustees The Leland Standford Junior University Injectable bioartificial tissue matrix
WO2005108981A1 (en) 2004-05-12 2005-11-17 The Walter And Eliza Hall Institute Of Medical Research A method of cell isolation
US7764995B2 (en) 2004-06-07 2010-07-27 Cardiac Pacemakers, Inc. Method and apparatus to modulate cellular regeneration post myocardial infarct
EP1778120A4 (en) * 2004-07-15 2009-07-08 Dentigenix Inc MINERALIZING COMPOSITE MATERIALS FOR RECONSTITUTION OF TEETH
CN101043899B (zh) * 2004-08-19 2011-03-30 比奥根艾迪克Ma公司 重折叠转化型生长因子beta家族蛋白
MX2007002029A (es) * 2004-08-19 2007-03-28 Biogen Idec Inc Variantes de neublastina.
DE602005013979D1 (de) * 2004-09-14 2009-05-28 Neurotex Ltd Verfahren und gerät für verstärktes wachstum von peripheren nerven und nervengewebe
US20060079927A1 (en) * 2004-10-08 2006-04-13 Medtronic Vascular, Inc., A Delaware Corporation Detachable joint catheter and method
US7235592B2 (en) 2004-10-12 2007-06-26 Zimmer Gmbh PVA hydrogel
CN102772824A (zh) * 2004-12-08 2012-11-14 渗透治疗有限公司 增强血管通路的方法和组合物
US8060219B2 (en) 2004-12-20 2011-11-15 Cardiac Pacemakers, Inc. Epicardial patch including isolated extracellular matrix with pacing electrodes
US7981065B2 (en) 2004-12-20 2011-07-19 Cardiac Pacemakers, Inc. Lead electrode incorporating extracellular matrix
US8874204B2 (en) 2004-12-20 2014-10-28 Cardiac Pacemakers, Inc. Implantable medical devices comprising isolated extracellular matrix
US9050393B2 (en) 2005-02-08 2015-06-09 Bruce N. Saffran Medical devices and methods for modulation of physiology using device-based surface chemistry
EP1848470A2 (en) * 2005-02-17 2007-10-31 Abbott Cardiovascular Systems, Inc. Coatings for implantable medical devices containing attractants for endothelial cells
WO2006091706A1 (en) 2005-02-23 2006-08-31 Zimmer Technology, Inc. Blend hydrogels and methods of making
US7851189B2 (en) * 2005-03-07 2010-12-14 Boston Scientific Scimed, Inc. Microencapsulated compositions for endoluminal tissue engineering
DE602006014814D1 (de) * 2005-04-21 2010-07-22 Massachusetts Inst Technology Materialien und verfahren zur änderung einer immunreaktion auf exogene und endogene immunogene, einschliesslich genidentischer und nicht-genidentischer zellen, gewebe oder organe
EP1901680B1 (en) * 2005-06-21 2015-04-15 Shire Regenerative Medicine, Inc. Crypreservation of biocompatible material
DK2407484T3 (en) 2005-06-24 2016-09-05 The Walter And Eliza Hall Inst Of Medical Res Therapeutic pro-apoptotic BH3-like molecules, and methods of generating and / or selecting those
US20070048383A1 (en) * 2005-08-25 2007-03-01 Helmus Michael N Self-assembled endovascular structures
DE102005040816A1 (de) * 2005-08-29 2007-03-15 Skh-Gmbh Leitschiene für die Regeneration von degeneriertem neuronalen Gewebe
EP1926459B1 (en) 2005-09-19 2015-01-07 Histogenics Corporation Cell-support matrix having narrowly defined uniformly vertically and non-randomly organized porosity and pore density and a method for preparation thereof
US20070190165A1 (en) * 2005-10-21 2007-08-16 Brey Eric M Tissue-specific basement membrane gels
US20100204783A1 (en) * 2005-12-06 2010-08-12 Helen Marie Nugent Methods and compositions for enhancing vascular access
EP1957124A2 (en) 2005-12-07 2008-08-20 Zimmer Inc. Methods of bonding or modifying hydrogels using irradiation
US8017107B2 (en) 2005-12-22 2011-09-13 Zimmer, Inc. Perfluorocyclobutane crosslinked hydrogels
TWI501774B (zh) 2006-02-27 2015-10-01 Biogen Idec Inc 神經性病症之治療
ES2450065T3 (es) * 2006-03-01 2014-03-21 Biogen Idec Ma Inc. Composiciones y métodos para la administración de proteínas de la familia de ligandos del GDNF
US8110242B2 (en) 2006-03-24 2012-02-07 Zimmer, Inc. Methods of preparing hydrogel coatings
US8092818B2 (en) * 2006-05-17 2012-01-10 Boston Scientific Scimed, Inc. Medical devices having bioactive surfaces
US7625552B2 (en) * 2006-05-30 2009-12-01 Boston Scientific Scimed, Inc. Bioactive polymers for imparting bioactive character to hydrophobic medical article surfaces
WO2007147014A2 (en) * 2006-06-13 2007-12-21 Fmc Biopolymer As Method and systems for using biopolymer-based beads and hydrogels
AU2007275764B2 (en) 2006-07-18 2013-11-14 University Of Utah Research Foundation Methods for treating pain and screening analgesic compounds
JP4569543B2 (ja) * 2006-08-18 2010-10-27 ニプロ株式会社 膨潤可能な棒状体を備えた組織再生器具の前駆体
EP2468314A1 (en) * 2006-09-06 2012-06-27 Boston Scientific Limited Medical devices having a coating for promoting endothelial cell adhesion
WO2008063878A2 (en) * 2006-11-06 2008-05-29 Bonwrx, Inc. Nerve regeneration device
WO2008057580A2 (en) * 2006-11-07 2008-05-15 Pervasis Therapeutics, Inc. Materials and methods for treating and managing angiogenesis-mediated diseases
WO2008103744A1 (en) * 2007-02-20 2008-08-28 Rutgers, The State University Of New Jersey Nerve guidance tubes
WO2008112163A1 (en) * 2007-03-09 2008-09-18 Corning Incorporated Gum coatings for cell culture, methods of manufacture and methods of use
US8080418B2 (en) * 2007-03-09 2011-12-20 Corning Incorporated Method of making a three dimensional cell culture matrix
WO2008113005A2 (en) * 2007-03-15 2008-09-18 Boston Scientific Scimed, Inc. Methods to improve the stability of cellular adhesive proteins and peptides
WO2008121331A1 (en) * 2007-03-30 2008-10-09 Pervasis Therapeutics, Inc. Materials and methods for treating nerve damage and promoting nerve repair and regeneration
WO2008122044A2 (en) * 2007-04-02 2008-10-09 Georgia Tech Research Corporation Implantable device for communicating with biological tissue
TWI445544B (zh) * 2007-05-01 2014-07-21 Biogen Idec Inc 增進血管形成之組合物及方法
ATE545441T1 (de) * 2007-06-13 2012-03-15 Pervasis Therapeutics Inc Verfahren und vorrichtungen zur minimal invasiven abgabe von zellhaltigen fliessfähigen zusammensetzungen
US8685107B2 (en) 2007-07-03 2014-04-01 Histogenics Corporation Double-structured tissue implant and a method for preparation and use thereof
US20090054984A1 (en) 2007-08-20 2009-02-26 Histogenics Corporation Method For Use Of A Double-Structured Tissue Implant For Treatment Of Tissue Defects
US7731988B2 (en) 2007-08-03 2010-06-08 Zimmer, Inc. Multi-polymer hydrogels
US20110135648A1 (en) * 2007-08-08 2011-06-09 Biogen Idec Ma Inc. Anti-neublastin antibodies and uses thereof
EP2182887B1 (en) 2007-08-20 2016-12-14 Histogenics Corporation A method for improvement of differentiation of mesenchymal stem cells using a double-structured tissue implant
US8062739B2 (en) 2007-08-31 2011-11-22 Zimmer, Inc. Hydrogels with gradient
ATE537857T1 (de) * 2007-09-21 2012-01-15 Boston Scient Scimed Inc Medizinische vorrichtungen mit oberflächen mit nanofaser-struktur
US20090104244A1 (en) * 2007-09-21 2009-04-23 Boston Scientific Scimed, Inc. Therapeutic agent-eluting medical devices having textured polymeric surfaces
WO2009043052A1 (en) * 2007-09-27 2009-04-02 Columbia University Methods and systems for forming biocompatible materials
US7947784B2 (en) 2007-11-16 2011-05-24 Zimmer, Inc. Reactive compounding of hydrogels
WO2009086535A2 (en) * 2007-12-27 2009-07-09 The Trustees Of Columbia University In The City Of New York Systems and methods for forming patterned extracellular matrix materials
US8034362B2 (en) 2008-01-04 2011-10-11 Zimmer, Inc. Chemical composition of hydrogels for use as articulating surfaces
US8668863B2 (en) * 2008-02-26 2014-03-11 Board Of Regents, The University Of Texas System Dendritic macroporous hydrogels prepared by crystal templating
US20090297581A1 (en) * 2008-05-28 2009-12-03 Boston Scientific Scimed, Inc. Medical devices having electrodeposited coatings
WO2009158325A2 (en) * 2008-06-25 2009-12-30 Boston Scientific Scimed, Inc. Medical devices having surface coatings
JP2011526186A (ja) * 2008-06-26 2011-10-06 ボストン サイエンティフィック サイムド，インコーポレイテッド 荷電材料を含む医療機器コーティング
US11090387B2 (en) * 2008-12-22 2021-08-17 The Trustees Of The University Of Pennsylvania Hydrolytically degradable polysaccharide hydrogels
US8574612B2 (en) * 2009-03-04 2013-11-05 Boston Scientific Scimed, Inc. Medical devices having a coating of biologic macromolecules
ES2644599T3 (es) * 2009-09-02 2017-11-29 Lifecell Corporation Injertos vasculares procedentes de matrices de tejido acelular
WO2011041478A1 (en) 2009-10-02 2011-04-07 Baxter International Inc. Hematopoietic stem cells for use in the treatment of a kidney injury
AU2010314994B2 (en) 2009-11-09 2016-10-06 Spotlight Technology Partners Llc Fragmented hydrogels
CN102695500A (zh) 2009-11-09 2012-09-26 聚光灯技术合伙有限责任公司 多糖基水凝胶
KR102173873B1 (ko) 2009-11-12 2020-11-04 브이셀 세라퓨틱스 인코포레이티드 포자를 닮은 세포들의 계군 및 그 용도
WO2011068778A1 (en) * 2009-12-03 2011-06-09 Lifecell Corporation Nerve treatment devices and methods
WO2011151832A1 (en) 2010-06-03 2011-12-08 Ramot At Tel-Aviv University Ltd. Malleable hydrogel hybrids made of self-assembled peptides and biocompatible polymers and uses thereof
EP2624874A4 (en) 2010-10-08 2014-04-02 Univ Texas ADHESIVE MEMBRANE WITH ALGINATE AND HYALURONIC ACID FOR BIOMEDICAL APPLICATIONS
WO2012048283A1 (en) 2010-10-08 2012-04-12 Board Of Regents, The University Of Texas System One-step processing of hydrogels for mechanically robust and chemically desired features
US9486404B2 (en) 2011-03-28 2016-11-08 The Trustees Of The University Of Pennsylvania Infarction treatment compositions and methods
EP2793966B1 (en) 2011-12-22 2018-03-28 Centre Hospitalier Universitaire Vaudois (CHUV) Selective plasma activation for medical implants and wound healing devices
EP2817014A2 (en) 2012-02-21 2014-12-31 Baxter International Inc Pharmaceutical composition comprising cd34+ cells
CN103542082B (zh) * 2012-07-16 2016-04-27 鸿富锦精密工业（深圳）有限公司 齿轮传动机构及机械臂连接结构
US11565027B2 (en) 2012-12-11 2023-01-31 Board Of Regents, The University Of Texas System Hydrogel membrane for adhesion prevention
TWI686205B (zh) 2013-05-31 2020-03-01 美國猶他大學研究基金會 芋螺毒素（ｃｏｎｏｔｏｘｉｎ）肽，其醫藥組合物及用途
AU2014324459B2 (en) 2013-09-30 2018-10-11 Bioactive Regenerative Therapeutics, Inc. Biomimetic hybrid gel compositions and methods of use
EP3038521B1 (en) * 2013-10-12 2019-05-01 Innovative Surface Technologies, Inc. Tissue scaffolds for electrically excitable cells
US20150141786A1 (en) * 2013-11-15 2015-05-21 Case Western Reserve University Interfacing With The Peripheral Nervous System (PNS) Using Targeted Fascicular Interface Device
CN105979978A (zh) 2013-12-30 2016-09-28 波士顿科学国际有限公司 功能化的光滑医疗器械涂层
US10077420B2 (en) 2014-12-02 2018-09-18 Histogenics Corporation Cell and tissue culture container
CN108884135B (zh) 2015-10-27 2024-03-26 昆士兰大学 治疗方法以及可用于其中的药剂
AU2017301511B2 (en) 2016-07-25 2023-05-18 Cerapedics, Inc. Peptide-coated calcium phosphate particles
US11150251B2 (en) 2016-10-07 2021-10-19 Clemson University Research Foundation Bi-functional arginine-glycine-aspartic acid (RGD) peptides and methods to promote angiogenesis

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4495288A (en) * 1981-03-13 1985-01-22 Damon Biotech, Inc. Method of culturing anchorage dependent cells
US4829000A (en) * 1985-08-30 1989-05-09 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Reconstituted basement membrane complex with biological activity
US5019087A (en) * 1986-10-06 1991-05-28 American Biomaterials Corporation Nerve regeneration conduit
US5092871A (en) * 1987-03-13 1992-03-03 Brown University Research Foundation Electrically-charged nerve guidance channels
US5030225A (en) * 1987-03-13 1991-07-09 Brown University Research Foundation Electrically-charged nerve guidance channels
FR2616318A1 (fr) * 1987-06-15 1988-12-16 Centre Nat Rech Scient Peau artificielle et son procede de preparation
US5147797A (en) * 1987-08-25 1992-09-15 Regents Of The University Of Minnesota Polypeptides with fibronectin activity
US5171271A (en) * 1987-08-25 1992-12-15 Regents Of The University Of Minnesota Polypeptides with fibronectin activity
US5294551A (en) * 1987-08-25 1994-03-15 Regents Of The University Of Minnesota Cell culture substrate coated with polypeptides having fibronectin activity
US5202120A (en) * 1987-09-11 1993-04-13 Case Western Reserve University Methods of reducing glial scar formation and promoting axon and blood vessel growth and/or regeneration through the use of activated immature astrocytes
SE8703625D0 (sv) * 1987-09-18 1987-09-18 Kabivitrum Ab New medical use
US5158881A (en) * 1987-11-17 1992-10-27 Brown University Research Foundation Method and system for encapsulating cells in a tubular extrudate in separate cell compartments
US5106627A (en) * 1987-11-17 1992-04-21 Brown University Research Foundation Neurological therapy devices
US5156844A (en) * 1987-11-17 1992-10-20 Brown University Research Foundation Neurological therapy system
US5283187A (en) * 1987-11-17 1994-02-01 Brown University Research Foundation Cell culture-containing tubular capsule produced by co-extrusion
US5250414A (en) * 1988-11-04 1993-10-05 Erziehungsdirektion Of The Canton Zurich Diagnostic methods using neurite growth regulatory factors
US5011486A (en) * 1988-11-18 1991-04-30 Brown University Research Foundation Composite nerve guidance channels
US5082670A (en) * 1988-12-15 1992-01-21 The Regents Of The University Of California Method of grafting genetically modified cells to treat defects, disease or damage or the central nervous system
US5026381A (en) * 1989-04-20 1991-06-25 Colla-Tec, Incorporated Multi-layered, semi-permeable conduit for nerve regeneration comprised of type 1 collagen, its method of manufacture and a method of nerve regeneration using said conduit
US4963146A (en) * 1989-04-20 1990-10-16 Colla-Tec Incorporated Multi-layered, semi-permeable conduit for nerve regeneration
US5354736A (en) * 1989-08-14 1994-10-11 Regents Of The University Of California Synthetic compounds and compositions with enhanced cell binding
US5330911A (en) * 1989-09-28 1994-07-19 Board Of Regents, The University Of Texas System Surfaces having desirable cell adhesive effects
US5081031A (en) * 1989-12-14 1992-01-14 Regents Of The University Of Minnesota Synthetic polypeptide with type iv collagen activity
US5082926A (en) * 1989-12-14 1992-01-21 Regents Of The University Of Minnesota Polypeptide with type iv collagen cell adhesion, spreading and motility activity
AU8649391A (en) * 1990-08-15 1992-03-17 University Of Miami Autotransplantation of schwann cells to promote nervous system repair
ES2107537T3 (es) * 1991-04-25 1997-12-01 Univ Brown Res Found Vehiculo inmunoaislante biocompatible implantable para suministrar productos terapeuticos seleccionados.
CA2113118C (en) * 1991-07-08 2002-09-17 Samuel Weiss Novel growth factor-responsive progenitor cells which can be proliferated in vitro
WO1993010722A2 (en) * 1991-11-26 1993-06-10 Research Development Foundation Fetal membrane tubes for nerve and vessel grafts
JPH07503467A (ja) * 1992-01-23 1995-04-13 ニューヨーク ユニヴァーシティー 細胞を脳に移植する方法及びその治療使用
US5279966A (en) * 1992-04-02 1994-01-18 The Trustees Of Columbia University In The City Of New York Cloning, expression and uses of a novel secreted protein, F-spondin
US5834029A (en) * 1994-07-20 1998-11-10 Cytotherapeutics, Inc. Nerve guidance channel containing bioartificial three-dimensional hydrogel extracellular matrix derivatized with cell adhesive peptide fragment

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US5834029A (en) 1998-11-10
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AU3142395A (en) 1996-02-16

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